Operative Dentistry, ISSN 0361-7734, 05/2009, Volume 34, Issue 3, pp. 280 - 287
This study evaluated the influence of surface treatments and metal primers on the bond strength of resin cements to a yttrium-stabilized tetragonal zirconia...
FLEXURAL STRENGTH | DURABILITY | LUTING CEMENTS | FRACTURE-TOUGHNESS | OXIDE | ADHESIVE RESIN | IN-VITRO EVALUATION | DENTISTRY, ORAL SURGERY & MEDICINE | NOBLE-METAL | PRIMERS | DENTAL CERAMICS | Bisphenol A-Glycidyl Methacrylate - chemistry | Microscopy, Electron, Scanning | Shear Strength | Thiouracil - chemistry | Thiouracil - analogs & derivatives | Dental Porcelain - chemistry | Humans | Resin Cements - chemistry | Thiones - chemistry | Dental Cements - chemistry | Stress, Mechanical | Dentin - ultrastructure | Materials Testing | Organophosphorus Compounds - chemistry | Methacrylates - chemistry | Dental Etching | Lasers, Solid-State | Surface Properties | Zirconium - chemistry | Dental Bonding | Aluminum Oxide - chemistry | Yttrium - chemistry
FLEXURAL STRENGTH | DURABILITY | LUTING CEMENTS | FRACTURE-TOUGHNESS | OXIDE | ADHESIVE RESIN | IN-VITRO EVALUATION | DENTISTRY, ORAL SURGERY & MEDICINE | NOBLE-METAL | PRIMERS | DENTAL CERAMICS | Bisphenol A-Glycidyl Methacrylate - chemistry | Microscopy, Electron, Scanning | Shear Strength | Thiouracil - chemistry | Thiouracil - analogs & derivatives | Dental Porcelain - chemistry | Humans | Resin Cements - chemistry | Thiones - chemistry | Dental Cements - chemistry | Stress, Mechanical | Dentin - ultrastructure | Materials Testing | Organophosphorus Compounds - chemistry | Methacrylates - chemistry | Dental Etching | Lasers, Solid-State | Surface Properties | Zirconium - chemistry | Dental Bonding | Aluminum Oxide - chemistry | Yttrium - chemistry
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 02/2017, Volume 127, pp. 159 - 165
A series of novel thiouracil derivatives containing a triazolo-thiadiazole moiety ( ) have been synthesized by structural modifications on a lead SecA...
SecA inhibitors | Molecular simulation | Antibacterial activity | Triazolo-thiadiazole | Thiouracil | INSERTION | CHEMISTRY, MEDICINAL | CONFORMER GENERATION | ANALOGS | IDENTIFICATION | COLI PREPROTEIN TRANSLOCASE | PROTEIN SECRETION | BACTERIAL-RESISTANCE | Staphylococcus aureus - enzymology | Triazoles - chemistry | Bacterial Proteins - chemistry | Enzyme Inhibitors - chemical synthesis | Thiadiazoles - chemistry | Anti-Bacterial Agents - chemistry | Enzyme Inhibitors - chemistry | Drug Design | SEC Translocation Channels - chemistry | Thiouracil - chemical synthesis | SEC Translocation Channels - metabolism | SEC Translocation Channels - antagonists & inhibitors | Bacterial Proteins - antagonists & inhibitors | Thiouracil - chemistry | Chemistry Techniques, Synthetic | Enzyme Inhibitors - metabolism | Enzyme Inhibitors - pharmacology | Adenosine Triphosphatases - metabolism | Anti-Bacterial Agents - metabolism | Bacillus subtilis - enzymology | Anti-Bacterial Agents - chemical synthesis | Adenosine Triphosphatases - antagonists & inhibitors | Thiouracil - metabolism | Adenosine Triphosphatases - chemistry | Bacterial Proteins - metabolism | Protein Conformation | Anti-Bacterial Agents - pharmacology | Molecular Docking Simulation | Staphylococcus aureus - drug effects | Thiouracil - pharmacology | Bacillus subtilis - drug effects | Adenosine triphosphatase | Triazoles | Antibacterial agents
SecA inhibitors | Molecular simulation | Antibacterial activity | Triazolo-thiadiazole | Thiouracil | INSERTION | CHEMISTRY, MEDICINAL | CONFORMER GENERATION | ANALOGS | IDENTIFICATION | COLI PREPROTEIN TRANSLOCASE | PROTEIN SECRETION | BACTERIAL-RESISTANCE | Staphylococcus aureus - enzymology | Triazoles - chemistry | Bacterial Proteins - chemistry | Enzyme Inhibitors - chemical synthesis | Thiadiazoles - chemistry | Anti-Bacterial Agents - chemistry | Enzyme Inhibitors - chemistry | Drug Design | SEC Translocation Channels - chemistry | Thiouracil - chemical synthesis | SEC Translocation Channels - metabolism | SEC Translocation Channels - antagonists & inhibitors | Bacterial Proteins - antagonists & inhibitors | Thiouracil - chemistry | Chemistry Techniques, Synthetic | Enzyme Inhibitors - metabolism | Enzyme Inhibitors - pharmacology | Adenosine Triphosphatases - metabolism | Anti-Bacterial Agents - metabolism | Bacillus subtilis - enzymology | Anti-Bacterial Agents - chemical synthesis | Adenosine Triphosphatases - antagonists & inhibitors | Thiouracil - metabolism | Adenosine Triphosphatases - chemistry | Bacterial Proteins - metabolism | Protein Conformation | Anti-Bacterial Agents - pharmacology | Molecular Docking Simulation | Staphylococcus aureus - drug effects | Thiouracil - pharmacology | Bacillus subtilis - drug effects | Adenosine triphosphatase | Triazoles | Antibacterial agents
Journal Article
Acta Odontologica Scandinavica, ISSN 0001-6357, 01/2013, Volume 71, Issue 1, pp. 196 - 204
Abstract Objective. The purpose of the current study was to evaluate the effect of thione-based metal priming agents on the adhesive behavior of a Ag-Pd-Cu-Au...
thiol | thiouracil | thione | tri-n-butylborane | OPAQUE RESIN | MONOMERS | DENTISTRY, ORAL SURGERY & MEDICINE | PRIMERS | DENTURE | RAMAN | Boron Compounds - chemistry | Gold - chemistry | Shear Strength | Thiouracil - chemistry | Methylmethacrylates - chemistry | Thiouracil - analogs & derivatives | Resin Cements - chemistry | Thiones - chemistry | Silver - chemistry | Materials Testing | Dental Alloys - chemistry | Hot Temperature | Methacrylates - chemistry | Acrylic Resins - chemistry | Copper - chemistry | X-Ray Diffraction | Dental Stress Analysis | Statistics, Nonparametric | Sulfhydryl Compounds - chemistry | Triazines - chemistry | Dental Bonding | Sulfur Compounds - chemistry | Palladium - chemistry | Dentin-Bonding Agents - chemistry | Tri-n-butylborane | Thiol | Thione | Thiouracil
thiol | thiouracil | thione | tri-n-butylborane | OPAQUE RESIN | MONOMERS | DENTISTRY, ORAL SURGERY & MEDICINE | PRIMERS | DENTURE | RAMAN | Boron Compounds - chemistry | Gold - chemistry | Shear Strength | Thiouracil - chemistry | Methylmethacrylates - chemistry | Thiouracil - analogs & derivatives | Resin Cements - chemistry | Thiones - chemistry | Silver - chemistry | Materials Testing | Dental Alloys - chemistry | Hot Temperature | Methacrylates - chemistry | Acrylic Resins - chemistry | Copper - chemistry | X-Ray Diffraction | Dental Stress Analysis | Statistics, Nonparametric | Sulfhydryl Compounds - chemistry | Triazines - chemistry | Dental Bonding | Sulfur Compounds - chemistry | Palladium - chemistry | Dentin-Bonding Agents - chemistry | Tri-n-butylborane | Thiol | Thione | Thiouracil
Journal Article
Journal of Prosthetic Dentistry, ISSN 0022-3913, 2011, Volume 106, Issue 6, pp. 378 - 385
Statement of problem Although the effectiveness of primers for resin bonding to noble alloys has been demonstrated, no effective clinical technique for bonding...
Dentistry | MONOMERS | ENAMEL | DENTISTRY, ORAL SURGERY & MEDICINE | SURFACE-TREATMENT | RESISTANCE | FOLLOW-UP | PROSTHESES | GOLD ALLOY | FIXED PARTIAL DENTURES | STRENGTHS | PROSTHODONTICS | Boron Compounds - chemistry | Shear Strength | Temperature | Thiouracil - chemistry | Methylmethacrylates - chemistry | Thiouracil - analogs & derivatives | Humans | Resin Cements - chemistry | Silver - chemistry | Dental Cements - chemistry | Silicon Compounds - chemistry | Stress, Mechanical | Materials Testing | Metal Ceramic Alloys - chemistry | Methacrylates - chemistry | Gold Alloys - chemistry | Carbon Compounds, Inorganic - chemistry | Copper - chemistry | Dental Etching - methods | Surface Properties | Triazines - chemistry | Dental Bonding | Aluminum Oxide - chemistry | Palladium - chemistry | Implants, Artificial | Prosthesis | Analysis | Alloys | Gums and resins industry | College teachers | Universities and colleges
Dentistry | MONOMERS | ENAMEL | DENTISTRY, ORAL SURGERY & MEDICINE | SURFACE-TREATMENT | RESISTANCE | FOLLOW-UP | PROSTHESES | GOLD ALLOY | FIXED PARTIAL DENTURES | STRENGTHS | PROSTHODONTICS | Boron Compounds - chemistry | Shear Strength | Temperature | Thiouracil - chemistry | Methylmethacrylates - chemistry | Thiouracil - analogs & derivatives | Humans | Resin Cements - chemistry | Silver - chemistry | Dental Cements - chemistry | Silicon Compounds - chemistry | Stress, Mechanical | Materials Testing | Metal Ceramic Alloys - chemistry | Methacrylates - chemistry | Gold Alloys - chemistry | Carbon Compounds, Inorganic - chemistry | Copper - chemistry | Dental Etching - methods | Surface Properties | Triazines - chemistry | Dental Bonding | Aluminum Oxide - chemistry | Palladium - chemistry | Implants, Artificial | Prosthesis | Analysis | Alloys | Gums and resins industry | College teachers | Universities and colleges
Journal Article
5.
Full Text
Effects of primers containing sulfur and phosphate monomers on bonding type IV gold alloy
Journal of Dentistry, ISSN 0300-5712, 2008, Volume 36, Issue 8, pp. 595 - 599
Abstract Objective The purpose of the present study was to evaluate the effect of five primers (two sulfur, one phosphate, and two sulfur–phosphate...
Dentistry | Primer | Adhesion | Surface treatment | Metal alloy | metal alloy | RESIN | surface treatment | primer | DENTISTRY, ORAL SURGERY & MEDICINE | METAL PRIMER | STRENGTH | adhesion | FIXED PARTIAL DENTURES | SURFACE CHARACTERIZATION | Temperature | Thiouracil - analogs & derivatives | Humans | Oxides - chemistry | Resin Cements - chemistry | Phosphates - chemistry | Composite Resins - chemistry | Dental Cements - chemistry | Methacrylates - chemistry | Carbon - chemistry | Copper - chemistry | Oxygen - chemistry | Triazines - chemistry | Sulfur - chemistry | Boron Compounds - chemistry | Shear Strength | Thiouracil - chemistry | Aluminum - chemistry | Thiones - chemistry | Electron Probe Microanalysis | Silver - chemistry | Materials Testing | Dental Etching | Gold Alloys - chemistry | Dental Bonding | Aluminum Oxide - chemistry | Studies | Gold | Bond strength | Curing | Adhesive bonding | Standard deviation | Alumina
Dentistry | Primer | Adhesion | Surface treatment | Metal alloy | metal alloy | RESIN | surface treatment | primer | DENTISTRY, ORAL SURGERY & MEDICINE | METAL PRIMER | STRENGTH | adhesion | FIXED PARTIAL DENTURES | SURFACE CHARACTERIZATION | Temperature | Thiouracil - analogs & derivatives | Humans | Oxides - chemistry | Resin Cements - chemistry | Phosphates - chemistry | Composite Resins - chemistry | Dental Cements - chemistry | Methacrylates - chemistry | Carbon - chemistry | Copper - chemistry | Oxygen - chemistry | Triazines - chemistry | Sulfur - chemistry | Boron Compounds - chemistry | Shear Strength | Thiouracil - chemistry | Aluminum - chemistry | Thiones - chemistry | Electron Probe Microanalysis | Silver - chemistry | Materials Testing | Dental Etching | Gold Alloys - chemistry | Dental Bonding | Aluminum Oxide - chemistry | Studies | Gold | Bond strength | Curing | Adhesive bonding | Standard deviation | Alumina
Journal Article
Molecular Diversity, ISSN 1381-1991, 11/2017, Volume 21, Issue 4, pp. 967 - 983
Thymidylate synthase (TS), one of folate-dependent enzymes, is a key and well-recognized target for anticancer agents. In this study, a series of...
Life Sciences | Biochemistry, general | Polymer Sciences | Pharmacy | Docking | 6-Aryl-5-cyano thiouracil | Anticancer | Thymidylate synthase | Organic Chemistry | DNA-BINDING | DESIGN | LEUCOVORIN | CHEMISTRY, MEDICINAL | COMPLEXES | FLUOROURACIL | CHEMISTRY, MULTIDISCIPLINARY | CHEMOTHERAPY | BIOLOGICAL EVALUATION | IRINOTECAN | CANCER STATISTICS | CHEMISTRY, APPLIED | Thiouracil - chemistry | Chemistry Techniques, Synthetic | Enzyme Inhibitors - metabolism | Antineoplastic Agents - chemical synthesis | Humans | Enzyme Inhibitors - pharmacology | Thymidylate Synthase - metabolism | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Enzyme Inhibitors - chemical synthesis | Antineoplastic Agents - metabolism | Thiouracil - metabolism | Enzyme Inhibitors - chemistry | Cell Line, Tumor | Thymidylate Synthase - chemistry | Protein Conformation | Antineoplastic Agents - pharmacology | Molecular Docking Simulation | Thymidylate Synthase - antagonists & inhibitors | Thiouracil - chemical synthesis | Thiouracil - pharmacology | Drug Screening Assays, Antitumor | Antimitotic agents | Nitriles | Antineoplastic agents | Folic acid | Resveratrol | Cytotoxicity | Chemical reactions | Inhibitors | Chemical synthesis | Chemical compounds | Cancer
Life Sciences | Biochemistry, general | Polymer Sciences | Pharmacy | Docking | 6-Aryl-5-cyano thiouracil | Anticancer | Thymidylate synthase | Organic Chemistry | DNA-BINDING | DESIGN | LEUCOVORIN | CHEMISTRY, MEDICINAL | COMPLEXES | FLUOROURACIL | CHEMISTRY, MULTIDISCIPLINARY | CHEMOTHERAPY | BIOLOGICAL EVALUATION | IRINOTECAN | CANCER STATISTICS | CHEMISTRY, APPLIED | Thiouracil - chemistry | Chemistry Techniques, Synthetic | Enzyme Inhibitors - metabolism | Antineoplastic Agents - chemical synthesis | Humans | Enzyme Inhibitors - pharmacology | Thymidylate Synthase - metabolism | Structure-Activity Relationship | Antineoplastic Agents - chemistry | Enzyme Inhibitors - chemical synthesis | Antineoplastic Agents - metabolism | Thiouracil - metabolism | Enzyme Inhibitors - chemistry | Cell Line, Tumor | Thymidylate Synthase - chemistry | Protein Conformation | Antineoplastic Agents - pharmacology | Molecular Docking Simulation | Thymidylate Synthase - antagonists & inhibitors | Thiouracil - chemical synthesis | Thiouracil - pharmacology | Drug Screening Assays, Antitumor | Antimitotic agents | Nitriles | Antineoplastic agents | Folic acid | Resveratrol | Cytotoxicity | Chemical reactions | Inhibitors | Chemical synthesis | Chemical compounds | Cancer
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 03/2015, Volume 43, Issue 5, pp. 2499 - 2512
2-Thiouracil-containing nucleosides are essential modified units of natural and synthetic nucleic acids. In particular, the 5-substituted-2-thiouridines (S2Us)...
WATSON-CRICK | OLIGODEOXYNUCLEOTIDES | THYMIDINE ANALOGS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MODIFIED NUCLEOSIDE | WOBBLE CODON BINDING | ANTICODON | 2-THIOURIDINE | MODIFIED NUCLEOTIDES | NUCLEIC-ACIDS | Nucleic Acid Denaturation | Thiouracil - chemistry | Nucleic Acid Heteroduplexes - genetics | Thiouridine - analogs & derivatives | Models, Chemical | Models, Molecular | Thiouridine - chemistry | RNA - chemistry | Adenine - chemistry | Nucleic Acid Heteroduplexes - chemistry | RNA - genetics | DNA - genetics | Thermodynamics | DNA - chemistry | Base Pairing | Guanine - chemistry | Nucleic Acid Conformation | Circular Dichroism | Chemical Biology and Nucleic Acid Chemistry
WATSON-CRICK | OLIGODEOXYNUCLEOTIDES | THYMIDINE ANALOGS | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MODIFIED NUCLEOSIDE | WOBBLE CODON BINDING | ANTICODON | 2-THIOURIDINE | MODIFIED NUCLEOTIDES | NUCLEIC-ACIDS | Nucleic Acid Denaturation | Thiouracil - chemistry | Nucleic Acid Heteroduplexes - genetics | Thiouridine - analogs & derivatives | Models, Chemical | Models, Molecular | Thiouridine - chemistry | RNA - chemistry | Adenine - chemistry | Nucleic Acid Heteroduplexes - chemistry | RNA - genetics | DNA - genetics | Thermodynamics | DNA - chemistry | Base Pairing | Guanine - chemistry | Nucleic Acid Conformation | Circular Dichroism | Chemical Biology and Nucleic Acid Chemistry
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 01/2010, Volume 16, Issue 4, pp. 1175 - 1185
In this paper, the effect of some commonly used antithyroid drugs and their analogues on peroxynitrite‐mediated nitration of proteins is described. The...
protein nitration | antithyroid drugs | peroxynitrite | selenium | antioxidants | SYNTHETIC ORGANOSELENIUM COMPOUNDS | TRACE-ELEMENT SELENIUM | LIPID-PEROXIDATION | GLUTATHIONE-PEROXIDASE | TOXIC MULTINODULAR GOITER | CHEMISTRY, MULTIDISCIPLINARY | I IODOTHYRONINE DEIODINASE | CYTOCHROME-C | MANGANESE SUPEROXIDE-DISMUTASE | HYDROGEN-PEROXIDE | THYROID-HORMONE SYNTHESIS | Selenium - chemistry | Thiouracil - chemistry | Methimazole - pharmacology | Thiouracil - analogs & derivatives | Methimazole - chemistry | Cytochromes c - chemistry | Thermodynamics | Animals | Cattle | Serum Albumin, Bovine - chemistry | Peroxynitrous Acid - chemistry | Antithyroid Agents - chemistry | Antithyroid Agents - pharmacology | Thiouracil - pharmacology | Tyrosine - chemistry | Oxidation
protein nitration | antithyroid drugs | peroxynitrite | selenium | antioxidants | SYNTHETIC ORGANOSELENIUM COMPOUNDS | TRACE-ELEMENT SELENIUM | LIPID-PEROXIDATION | GLUTATHIONE-PEROXIDASE | TOXIC MULTINODULAR GOITER | CHEMISTRY, MULTIDISCIPLINARY | I IODOTHYRONINE DEIODINASE | CYTOCHROME-C | MANGANESE SUPEROXIDE-DISMUTASE | HYDROGEN-PEROXIDE | THYROID-HORMONE SYNTHESIS | Selenium - chemistry | Thiouracil - chemistry | Methimazole - pharmacology | Thiouracil - analogs & derivatives | Methimazole - chemistry | Cytochromes c - chemistry | Thermodynamics | Animals | Cattle | Serum Albumin, Bovine - chemistry | Peroxynitrous Acid - chemistry | Antithyroid Agents - chemistry | Antithyroid Agents - pharmacology | Thiouracil - pharmacology | Tyrosine - chemistry | Oxidation
Journal Article
Langmuir, ISSN 0743-7463, 07/2014, Volume 30, Issue 29, pp. 8980 - 8989
We demonstrated a facile one-step synthesis strategy for the preparation of a large-scale reduced graphene oxide multilayered film doped with gold...
LAYER GRAPHENE | THIN-FILMS | FUNCTIONALIZATION | OXIDE | OXYGEN REDUCTION | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | METAL NANOPARTICLES | CHEMISTRY, MULTIDISCIPLINARY | CARBON NANOTUBES | SCATTERING | COMPOSITE | Gold - chemistry | Aniline Compounds - analysis | Limit of Detection | Electrochemical Techniques | Oxidation-Reduction | Metal Nanoparticles - chemistry | Spectrum Analysis, Raman - methods | Thiouracil - analysis | Sulfhydryl Compounds - analysis | Hydrogen Peroxide - analysis | Biosensing Techniques | Oxygen - chemistry | Graphite - chemistry | Metal Nanoparticles - ultrastructure
LAYER GRAPHENE | THIN-FILMS | FUNCTIONALIZATION | OXIDE | OXYGEN REDUCTION | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | METAL NANOPARTICLES | CHEMISTRY, MULTIDISCIPLINARY | CARBON NANOTUBES | SCATTERING | COMPOSITE | Gold - chemistry | Aniline Compounds - analysis | Limit of Detection | Electrochemical Techniques | Oxidation-Reduction | Metal Nanoparticles - chemistry | Spectrum Analysis, Raman - methods | Thiouracil - analysis | Sulfhydryl Compounds - analysis | Hydrogen Peroxide - analysis | Biosensing Techniques | Oxygen - chemistry | Graphite - chemistry | Metal Nanoparticles - ultrastructure
Journal Article
Organic & biomolecular chemistry, ISSN 1477-0520, 08/2014, Volume 12, Issue 30, pp. 5634 - 5644
A general and efficient approach was developed for the introduction of S-functionality at the C-5 position of cytosine and uracil nucleosides and their...
Chemistry, Organic - methods | Thiouracil - chemistry | Cytosine - chemical synthesis | Pyrimidine Nucleosides - chemistry | Disulfides - chemistry | Lamivudine - chemistry | Lamivudine - analogs & derivatives | Cytosine - chemistry | Pyrimidine Nucleosides - chemical synthesis | Thiouracil - chemical synthesis | Disulfides - chemical synthesis
Chemistry, Organic - methods | Thiouracil - chemistry | Cytosine - chemical synthesis | Pyrimidine Nucleosides - chemistry | Disulfides - chemistry | Lamivudine - chemistry | Lamivudine - analogs & derivatives | Cytosine - chemistry | Pyrimidine Nucleosides - chemical synthesis | Thiouracil - chemical synthesis | Disulfides - chemical synthesis
Journal Article
Molecular Diversity, ISSN 1381-1991, 8/2011, Volume 15, Issue 3, pp. 721 - 731
Reaction of barbituric acid (BA), 1,3-dimethyl barbituric acid (DMBA) and 2-thiobarbituric acid (TBA) with cyanogen bromide and various aldehydes in presence...
Life Sciences | Biochemistry, general | Polymer Sciences | Cyanogen bromide | Pharmacy | Barbituric acid | Spiro[furo[2,3- d ]pyrimidine | Thiouracil | Uracil | Organic Chemistry | Spiro[furo[2,3-d]pyrimidine | OXIDATION | CYANOGEN-BROMIDE | CHEMISTRY, MEDICINAL | BENZYLIC ALCOHOLS | BARBITURIC-ACID DERIVATIVES | CHEMISTRY, APPLIED | CHEMISTRY, MULTIDISCIPLINARY | Barbiturates - metabolism | Magnetic Resonance Spectroscopy | Thiobarbiturates - chemistry | Pentanones - chemistry | Pyrimidines - chemical synthesis | Crystallography, X-Ray | Pyrimidines - chemistry | Barbiturates - chemical synthesis | Barbiturates - chemistry | Spiro Compounds - chemical synthesis | Molecular Structure | Ethylamines - chemistry | Pentanones - chemical synthesis | Cyanogen Bromide - chemistry | Spiro Compounds - chemistry | Aldehydes - chemistry | Sulfur compounds | Nitriles | Pyrimidines | Universities and colleges | Aldehydes | Chemical reactions | Chemical synthesis | Sulfur
Life Sciences | Biochemistry, general | Polymer Sciences | Cyanogen bromide | Pharmacy | Barbituric acid | Spiro[furo[2,3- d ]pyrimidine | Thiouracil | Uracil | Organic Chemistry | Spiro[furo[2,3-d]pyrimidine | OXIDATION | CYANOGEN-BROMIDE | CHEMISTRY, MEDICINAL | BENZYLIC ALCOHOLS | BARBITURIC-ACID DERIVATIVES | CHEMISTRY, APPLIED | CHEMISTRY, MULTIDISCIPLINARY | Barbiturates - metabolism | Magnetic Resonance Spectroscopy | Thiobarbiturates - chemistry | Pentanones - chemistry | Pyrimidines - chemical synthesis | Crystallography, X-Ray | Pyrimidines - chemistry | Barbiturates - chemical synthesis | Barbiturates - chemistry | Spiro Compounds - chemical synthesis | Molecular Structure | Ethylamines - chemistry | Pentanones - chemical synthesis | Cyanogen Bromide - chemistry | Spiro Compounds - chemistry | Aldehydes - chemistry | Sulfur compounds | Nitriles | Pyrimidines | Universities and colleges | Aldehydes | Chemical reactions | Chemical synthesis | Sulfur
Journal Article
Dental Materials Journal, ISSN 0287-4547, 2010, Volume 29, Issue 2, pp. 177 - 187
This study evaluated the effects of metal primers on the bonding of adhesive resin to four pure metals (Au, Pd, Ag, Cu) and two noble alloys for porcelain...
Adhesive resin cement | Noble alloy for porcelain fusing | Metal primer | OPAQUE RESIN | IN-VITRO | MATERIALS SCIENCE, BIOMATERIALS | ENAMEL | DENTISTRY, ORAL SURGERY & MEDICINE | SURFACE-TREATMENT | STRENGTH | NICKEL-CHROMIUM ALLOY | FIXED PARTIAL DENTURES | Boron Compounds - chemistry | Gold - chemistry | Shear Strength | Temperature | Thiouracil - chemistry | Methylmethacrylates - chemistry | Thiouracil - analogs & derivatives | Humans | Resin Cements - chemistry | Silver - chemistry | Silicon Compounds - chemistry | Stress, Mechanical | Materials Testing | Metal Ceramic Alloys - chemistry | Dental Polishing - methods | Methacrylates - chemistry | Gold Alloys - chemistry | Carbon Compounds, Inorganic - chemistry | Copper - chemistry | Time Factors | Surface Properties | Triazines - chemistry | Dental Bonding | Palladium - chemistry
Adhesive resin cement | Noble alloy for porcelain fusing | Metal primer | OPAQUE RESIN | IN-VITRO | MATERIALS SCIENCE, BIOMATERIALS | ENAMEL | DENTISTRY, ORAL SURGERY & MEDICINE | SURFACE-TREATMENT | STRENGTH | NICKEL-CHROMIUM ALLOY | FIXED PARTIAL DENTURES | Boron Compounds - chemistry | Gold - chemistry | Shear Strength | Temperature | Thiouracil - chemistry | Methylmethacrylates - chemistry | Thiouracil - analogs & derivatives | Humans | Resin Cements - chemistry | Silver - chemistry | Silicon Compounds - chemistry | Stress, Mechanical | Materials Testing | Metal Ceramic Alloys - chemistry | Dental Polishing - methods | Methacrylates - chemistry | Gold Alloys - chemistry | Carbon Compounds, Inorganic - chemistry | Copper - chemistry | Time Factors | Surface Properties | Triazines - chemistry | Dental Bonding | Palladium - chemistry
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 02/2018, Volume 28, Issue 4, pp. 787 - 792
Darapladib is one of the most potent Lp-PLA (Lipoprotein-associated phospholipase A ) inhibitor with an IC of 0.25 nM. We demonstrate that a crucial step of...
Darapladib | Regioselectivity | Thiouracil | Lp-PLA2 | Atherosclerosis | Lp-PLA | LP-PLA INHIBITORS | DESIGN | CHEMISTRY, MEDICINAL | TRIAZOLE DERIVATIVES | ANALOGS | CHEMISTRY, ORGANIC | DISCOVERY | POTENT | LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE-A2 | DISEASE | Catalytic Domain | Thiouracil - chemistry | Benzaldehydes - chemistry | Humans | Benzaldehydes - pharmacology | Oximes - chemical synthesis | Isomerism | Alkylation | Phospholipase A2 Inhibitors - pharmacology | Oximes - chemistry | 1-Alkyl-2-acetylglycerophosphocholine Esterase - antagonists & inhibitors | Oximes - pharmacology | Phospholipase A2 Inhibitors - chemistry | Phospholipase A2 Inhibitors - chemical synthesis | Benzaldehydes - chemical synthesis | 1-Alkyl-2-acetylglycerophosphocholine Esterase - chemistry | Enols
Darapladib | Regioselectivity | Thiouracil | Lp-PLA2 | Atherosclerosis | Lp-PLA | LP-PLA INHIBITORS | DESIGN | CHEMISTRY, MEDICINAL | TRIAZOLE DERIVATIVES | ANALOGS | CHEMISTRY, ORGANIC | DISCOVERY | POTENT | LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE-A2 | DISEASE | Catalytic Domain | Thiouracil - chemistry | Benzaldehydes - chemistry | Humans | Benzaldehydes - pharmacology | Oximes - chemical synthesis | Isomerism | Alkylation | Phospholipase A2 Inhibitors - pharmacology | Oximes - chemistry | 1-Alkyl-2-acetylglycerophosphocholine Esterase - antagonists & inhibitors | Oximes - pharmacology | Phospholipase A2 Inhibitors - chemistry | Phospholipase A2 Inhibitors - chemical synthesis | Benzaldehydes - chemical synthesis | 1-Alkyl-2-acetylglycerophosphocholine Esterase - chemistry | Enols
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 11/2013, Volume 69, pp. 591 - 600
A series of 6-aryl-5-cyano thiouracil derivatives ( to ) was synthesized from 6-aryl-4-hydrazino-2-thioxo-1,2-dihydropyrimidine-5-carbonitriles ( ). The...
Synthesis | Antifungal | Antibacterial | 6-Aryl-5-cyano thiouracils | Antioxidant activity | Radical scavenging | PYRIMIDINE-DERIVATIVES | CHEMISTRY, MEDICINAL | ANTITUMOR | BIOLOGICAL EVALUATION | AGENTS | INHIBITORS | 5-CYANO-6-ARYL-2-THIOURACIL | Antifungal Agents - pharmacology | Thiouracil - chemistry | Antioxidants - chemistry | Fungi - drug effects | Free Radical Scavengers - chemistry | Bacteria - drug effects | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Structure-Activity Relationship | Antioxidants - chemical synthesis | Antioxidants - pharmacology | Anti-Bacterial Agents - chemical synthesis | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Anti-Bacterial Agents - chemistry | Picrates - chemistry | Anti-Bacterial Agents - pharmacology | Molecular Structure | Biphenyl Compounds - chemistry | Thiouracil - chemical synthesis | Thiouracil - pharmacology | Drugstores | Organic compounds
Synthesis | Antifungal | Antibacterial | 6-Aryl-5-cyano thiouracils | Antioxidant activity | Radical scavenging | PYRIMIDINE-DERIVATIVES | CHEMISTRY, MEDICINAL | ANTITUMOR | BIOLOGICAL EVALUATION | AGENTS | INHIBITORS | 5-CYANO-6-ARYL-2-THIOURACIL | Antifungal Agents - pharmacology | Thiouracil - chemistry | Antioxidants - chemistry | Fungi - drug effects | Free Radical Scavengers - chemistry | Bacteria - drug effects | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Structure-Activity Relationship | Antioxidants - chemical synthesis | Antioxidants - pharmacology | Anti-Bacterial Agents - chemical synthesis | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Anti-Bacterial Agents - chemistry | Picrates - chemistry | Anti-Bacterial Agents - pharmacology | Molecular Structure | Biphenyl Compounds - chemistry | Thiouracil - chemical synthesis | Thiouracil - pharmacology | Drugstores | Organic compounds
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 01/2015, Volume 23, Issue 1, pp. 105 - 117
SAR summary of 5-cyano-6-aryl-2-thiouracil inhibitors. Protein translocation is essential for bacterial survival and the most important translocation mechanism...
SecA inhibitors | Enzyme inhibitors | Novel drugs | Drug resistance | Antimicrobials | TRANSLOCASE MOTOR | MULTIDRUG-RESISTANT | CHEMISTRY, MEDICINAL | CRYSTAL-STRUCTURE | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | PROTEIN-CONDUCTING CHANNELS | ACINETOBACTER-BAUMANNII | DIMERIC SECA | COLI | ATPASE SECA | KLEBSIELLA-PNEUMONIAE | Bacterial Proteins - antagonists & inhibitors | Thiouracil - chemistry | Anti-Infective Agents - pharmacology | Bacterial Proteins - chemistry | Enzyme Inhibitors - pharmacology | Adenosine Triphosphatases - metabolism | Models, Molecular | Structure-Activity Relationship | Enzyme Inhibitors - chemical synthesis | Anti-Infective Agents - chemical synthesis | Membrane Transport Proteins - chemistry | Protein Transport | SEC Translocation Channels | Adenosine Triphosphatases - antagonists & inhibitors | Anti-Infective Agents - chemistry | Drug Design | Adenosine Triphosphatases - chemistry | Bacterial Proteins - metabolism | Membrane Transport Proteins - metabolism | Molecular Docking Simulation | Thiouracil - chemical synthesis | Nitriles | Analysis
SecA inhibitors | Enzyme inhibitors | Novel drugs | Drug resistance | Antimicrobials | TRANSLOCASE MOTOR | MULTIDRUG-RESISTANT | CHEMISTRY, MEDICINAL | CRYSTAL-STRUCTURE | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | PROTEIN-CONDUCTING CHANNELS | ACINETOBACTER-BAUMANNII | DIMERIC SECA | COLI | ATPASE SECA | KLEBSIELLA-PNEUMONIAE | Bacterial Proteins - antagonists & inhibitors | Thiouracil - chemistry | Anti-Infective Agents - pharmacology | Bacterial Proteins - chemistry | Enzyme Inhibitors - pharmacology | Adenosine Triphosphatases - metabolism | Models, Molecular | Structure-Activity Relationship | Enzyme Inhibitors - chemical synthesis | Anti-Infective Agents - chemical synthesis | Membrane Transport Proteins - chemistry | Protein Transport | SEC Translocation Channels | Adenosine Triphosphatases - antagonists & inhibitors | Anti-Infective Agents - chemistry | Drug Design | Adenosine Triphosphatases - chemistry | Bacterial Proteins - metabolism | Membrane Transport Proteins - metabolism | Molecular Docking Simulation | Thiouracil - chemical synthesis | Nitriles | Analysis
Journal Article