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Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2012, Volume 55, Issue 24, pp. 10948 - 10957
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2007, Volume 50, Issue 22, pp. 5281 - 5292
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 12/2012, Volume 58, pp. 591 - 612
A series of new isoprenyl-thiourea and urea derivatives were synthesized by the reaction of alkyl or aryl isothiocyanate or isocyanate and primary amines. The... 
Isoprenyl-thiourea/urea derivative | Antifungal | Antibacterial | Anticancer | Structural requirements | Farnesyl diphosphate analogue | CANCER-CELLS | CHEMISTRY, MEDICINAL | D-GLUCOSAMINE | DISCOVERY | PROTEIN FARNESYLTRANSFERASE | PACLITAXEL | PYROPHOSPHATE | HYDROGEN-PEROXIDE | ANTICANCER DRUGS | AGENTS | INHIBITORS | Polyisoprenyl Phosphates - chemistry | Gram-Positive Bacteria - drug effects | Antineoplastic Agents - chemical synthesis | Humans | Antifungal Agents - chemical synthesis | Antifungal Agents - chemistry | Sesquiterpenes - chemical synthesis | Structure-Activity Relationship | Candida albicans - growth & development | Urea - chemistry | Dose-Response Relationship, Drug | Microbial Sensitivity Tests | Candida albicans - drug effects | Anti-Bacterial Agents - chemistry | Polyisoprenyl Phosphates - chemical synthesis | Urea - analogs & derivatives | Antineoplastic Agents - pharmacology | Molecular Structure | Gram-Positive Bacteria - growth & development | Antifungal Agents - pharmacology | Sesquiterpenes - chemistry | Antineoplastic Agents - chemistry | Anti-Bacterial Agents - chemical synthesis | HT29 Cells | Gram-Negative Bacteria - drug effects | Gram-Negative Bacteria - growth & development | Anti-Bacterial Agents - pharmacology | Cell Proliferation - drug effects | Polyisoprenyl Phosphates - pharmacology | Sesquiterpenes - pharmacology | Urea - pharmacology | Drug Screening Assays, Antitumor | Isocyanates | Urea | Heterocyclic compounds | Analysis
Journal Article
Tetrahedron, ISSN 0040-4020, 10/2015, Volume 71, Issue 42, pp. 7990 - 7997
The first synthesis of fradcarbazole A ( ) has been accomplished by using a biomimetic intramolecular cyclization/dehydration to construct the... 
Cytotoxicity | PKC-Beta | Fradcarbazole A | Staurosporine | Biomimetic synthesis | THIOUREAS | POTENT | ASSAY | BIOLOGY | CHEMISTRY | CHEMISTRY, ORGANIC | DERIVATIVES | Oxazoles
Journal Article
Journal of Heterocyclic Chemistry, ISSN 0022-152X, 03/2013, Volume 50, Issue 2, pp. 237 - 243
In this study, we have synthesized 1‐(4,6‐disubstitutedpyrimidin‐2‐yl)‐3‐(3,5‐dinitrobenzoyl)‐thiourea derivatives (1a, 1b, 1c, 1d, 1e, 1f, 1g, 1h) and... 
POTENT | MOIETY | SERIES | EFFICACY | 1-AROYL-3-ARYL-4-SUBSTITUTED IMIDAZOLE-2-THIONES | CHEMISTRY, ORGANIC | AGENTS | THIOUREA DERIVATIVES | INHIBITOR | EFFICIENT | Heterocyclic compounds | Nuclear magnetic resonance spectroscopy | Analysis
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 09/2016, Volume 22, Issue 40, pp. 14247 - 14256
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 2008, Volume 43, Issue 9, pp. 2011 - 2015
Journal Article