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threonine-trna ligase - genetics (60) 60
threonine-trna ligase - metabolism (51) 51
index medicus (43) 43
humans (34) 34
molecular sequence data (33) 33
biochemistry & molecular biology (32) 32
escherichia coli - genetics (28) 28
protein biosynthesis (28) 28
threonine-trna ligase - chemistry (27) 27
escherichia coli - enzymology (26) 26
amino acid sequence (24) 24
base sequence (22) 22
transfer rna (22) 22
mutation (21) 21
threonine-trna ligase - immunology (20) 20
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escherichia-coli (18) 18
nucleic acid conformation (18) 18
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threonine-trna ligase (17) 17
trna (17) 17
animals (16) 16
models, molecular (16) 16
amino acids (15) 15
binding sites (15) 15
genes, bacterial (15) 15
rna, messenger - metabolism (15) 15
amino acyl-trna synthetases - genetics (14) 14
male (13) 13
multidisciplinary sciences (13) 13
protein structure, tertiary (13) 13
amino acyl-trna synthetases - metabolism (12) 12
crystallography, x-ray (12) 12
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transfer-rna-synthetase (12) 12
ligases (11) 11
rna editing (11) 11
threonine (11) 11
threonyl-trna synthetase (11) 11
adult (10) 10
gene expression regulation (10) 10
gene expression regulation, bacterial (10) 10
kinetics (10) 10
myositis - immunology (10) 10
rna, messenger - genetics (10) 10
rna, transfer, thr - metabolism (10) 10
threonine - metabolism (10) 10
threonine-trna ligase - antagonists & inhibitors (10) 10
translation (10) 10
zinc ion (10) 10
aminoacyl-trna synthetase (9) 9
aminoacyl-trna synthetases (9) 9
autoantibodies (9) 9
discrimination (9) 9
expression (9) 9
plasmids (9) 9
rna, bacterial - metabolism (9) 9
sequence homology, amino acid (9) 9
transfer rna aminoacylation (9) 9
article (8) 8
bacteria (8) 8
enzymes (8) 8
evolution, molecular (8) 8
genetic aspects (8) 8
phylogeny (8) 8
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rna (8) 8
rna, transfer - metabolism (8) 8
saccharomyces cerevisiae - enzymology (8) 8
saccharomyces cerevisiae - genetics (8) 8
sequence alignment (8) 8
threonine-trna ligase - isolation & purification (8) 8
active-site (7) 7
aminoacylation (7) 7
crystallization (7) 7
dermatomyositis - immunology (7) 7
domain (7) 7
electrophoresis, polyacrylamide gel (7) 7
escherichia coli (7) 7
mechanism (7) 7
messenger rna (7) 7
microbiology (7) 7
mitochondria - enzymology (7) 7
myositis (7) 7
polymyositis (7) 7
protein conformation (7) 7
protein synthesis (7) 7
protein-synthesis (7) 7
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rna, transfer, amino acyl - metabolism (7) 7
amino acyl-trna synthetases - immunology (6) 6
analysis (6) 6
antisynthetase syndrome (6) 6
autoantibodies - analysis (6) 6
bacterial proteins - genetics (6) 6
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PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e81734
Twenty different aminoacyl-tRNA synthetases (ARSs) link each amino acid to their cognate tRNAs. Individual ARSs are also associated with various non-canonical... 
BREAST-CANCER | TARGET | SIGNAL | AIMP2 | PROTEIN INTERACTIONS | FANCD2 | INTERACTS | MULTIDISCIPLINARY SCIENCES | C-MYC | ASSIGNMENT | TRANSLATION | Humans | Molecular Sequence Data | Neoplasm Proteins - metabolism | Cytokines - chemistry | Mass Spectrometry | HEK293 Cells | Carrier Proteins - chemistry | Amino Acyl-tRNA Synthetases - chemistry | Amino Acyl-tRNA Synthetases - metabolism | Amino Acid Sequence | Computational Biology - methods | Threonine-tRNA Ligase - analysis | Cytokines - metabolism | RNA-Binding Proteins - chemistry | Neoplasm Proteins - chemistry | Nuclear Proteins | Protein Interaction Mapping - methods | Algorithms | Carrier Proteins - metabolism | Chromatography, Affinity | Threonine-tRNA Ligase - isolation & purification | Lysine-tRNA Ligase - metabolism | Protein Processing, Post-Translational | RNA-Binding Proteins - metabolism | Threonine-tRNA Ligase - metabolism | Physiological aspects | Usage | Research | Aminoacyl-tRNA synthetases | Mass spectrometry | Multiple sclerosis | Biomedical research | Peptides | Amino acids | Kinases | Proteins | Signal transduction | Cell growth | Tumor necrosis factor-TNF | Life sciences | Spectroscopy | Purification | tRNA | Threonine-tRNA ligase | Cloning | Mass spectroscopy | Topology | Precipitates | Computer science | Contaminants | Affinity | Scientific imaging | Autoimmune diseases | Aminoacyl-tRNA ligase | Cancer | Apoptosis
Journal Article
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 01/1986, Volume 165, Issue 1, pp. 198 - 203
Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
Amino Acyl-tRNA Synthetases - genetics | Threonine-tRNA Ligase - analysis | Escherichia coli - enzymology | Gene Expression Regulation | Homeostasis | RNA, Messenger - analysis | Threonine-tRNA Ligase - genetics | Transcription, Genetic | Chromosome Mapping | Mutation
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 10/1986, Volume 168, Issue 1, pp. 213 - 220
Journal Article
Methods, ISSN 1046-2023, 01/2017, Volume 113, pp. 64 - 71
Differential scanning fluorimetry (DSF) is a fluorescence-based assay to evaluate protein stability by determining protein melting temperatures. Here, we... 
Amino acid | tRNA | Differential scanning fluorimetry | Aminoacyl-tRNA synthetase | Histidyl-tRNA synthetase | SYPRO Orange | CRYSTALLIZATION | CARBONIC-ANHYDRASE | PROTEIN | SPECIFICITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | THERMAL SHIFT ASSAYS | BOMBYX-MORI | INHIBITION | STRUCTURAL BASIS | PURIFICATION | BINDING | Histidine-tRNA Ligase - antagonists & inhibitors | Protein Unfolding | Amino Acids - chemistry | RNA, Transfer, Amino Acid-Specific - metabolism | Substrate Specificity | Fluorometry - methods | Threonine-tRNA Ligase - genetics | Phase Transition | Histidine-tRNA Ligase - genetics | Threonine-tRNA Ligase - antagonists & inhibitors | Benzopyrans - chemistry | Amino Acids - metabolism | Threonine-tRNA Ligase - chemistry | Alanine-tRNA Ligase - genetics | Enzyme Inhibitors - chemistry | Escherichia coli Proteins - antagonists & inhibitors | Alanine-tRNA Ligase - metabolism | Fluorescent Dyes - chemistry | Transfer RNA Aminoacylation | Histidine-tRNA Ligase - metabolism | Escherichia coli - enzymology | Alanine-tRNA Ligase - antagonists & inhibitors | Muramidase - chemistry | Enzyme Stability | RNA, Transfer, Amino Acid-Specific - genetics | Escherichia coli Proteins - metabolism | Muramidase - metabolism | Histidine-tRNA Ligase - chemistry | Alanine-tRNA Ligase - chemistry | Escherichia coli - genetics | Escherichia coli Proteins - genetics | Protein Binding | Escherichia coli Proteins - chemistry | Threonine-tRNA Ligase - metabolism | Ligases | Transfer RNA | Amino acids | Usage | Analysis
Journal Article
Human Mutation, ISSN 1059-7794, 08/2014, Volume 35, Issue 8, pp. 983 - 989
ABSTRACT By way of whole‐exome sequencing, we identified a homozygous missense mutation in VARS2 in one subject with microcephaly and epilepsy associated with... 
aminoacyl tRNA syntethases | TARS2 | encephalomyopathy | VARS2 | OXPHOS defect | mitochondrial disease | Encephalomyopathy | Aminoacyl tRNA syntethases | Mitochondrial disease | CELLS | INVOLVEMENT | BRAIN-STEM | LEUKOENCEPHALOPATHY | GENE | DNA | GENETICS & HEREDITY | Mitochondria - enzymology | Saccharomyces cerevisiae - genetics | Humans | Mitochondrial Encephalomyopathies - enzymology | Infant | Male | Threonine-tRNA Ligase - genetics | HLA Antigens - genetics | RNA, Messenger - metabolism | Electron Transport Complex I - metabolism | Saccharomyces cerevisiae - metabolism | RNA, Transfer, Val - genetics | DNA, Mitochondrial - genetics | Mitochondria - genetics | Electron Transport Complex I - genetics | Isoenzymes - metabolism | Valine-tRNA Ligase - metabolism | Valine-tRNA Ligase - genetics | Child | RNA, Transfer, Thr - genetics | Fibroblasts - metabolism | Cell Line | DNA, Mitochondrial - metabolism | RNA, Transfer, Thr - metabolism | Isoenzymes - genetics | Mitochondrial Encephalomyopathies - genetics | RNA, Messenger - genetics | Mitochondria - pathology | HLA Antigens - metabolism | Polymorphism, Genetic | Mitochondrial Encephalomyopathies - pathology | RNA, Transfer, Val - metabolism | Homozygote | Heterozygote | Fibroblasts - cytology | Mutation | Threonine-tRNA Ligase - metabolism | Proteins | Care and treatment | Analysis | Epilepsy | Genetic aspects | Single nucleotide polymorphisms | Aminoacyl-tRNA synthetases | Transfer RNA
Journal Article
Journal Article
Molecular Biology and Evolution, ISSN 0737-4038, 11/2008, Volume 25, Issue 11, pp. 2369 - 2389
A comparative genomic analysis of 35 cyanobacterial strains has revealed that the gene complement of aminoacyl-tRNA synthetases (AARSs) and routes for... 
Gene duplication | Phylogeny | Aminoacyl-tRNA synthetase | Cyanobacteria | Domain shuffling | Horizontal gene transfer | ASPARAGINE SYNTHETASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | COLI YADB GENE | domain shuffling | MITOCHONDRIAL-DNA | horizontal gene transfer | MULTIPLE SEQUENCE ALIGNMENT | EVOLUTIONARY BIOLOGY | COMPLETE GENOME STRUCTURE | MOLECULAR PHYLOGENETICS | aminoacyl-tRNA synthetase | gene duplication | GLUTAMINYL-TRANSFER-RNA | HISTIDYL-TRANSFER-RNA | cyanobacteria | GENETICS & HEREDITY | phylogeny | HORIZONTAL GENE-TRANSFER | NUCLEOTIDE-SEQUENCE | Cyanobacteria - genetics | Gene Duplication | Cyanobacteria - classification | Threonine-tRNA Ligase - genetics | RNA, Transfer, Gln - metabolism | RNA, Transfer, Asn - metabolism | Histidine-tRNA Ligase - genetics | Genetic Variation | Arginine-tRNA Ligase - genetics | Aspartate-tRNA Ligase - metabolism | RNA, Transfer, Amino Acyl - metabolism | Amino Acyl-tRNA Synthetases - metabolism | RNA, Bacterial - metabolism | Amino Acyl-tRNA Synthetases - genetics | Protein Structure, Tertiary | Genome, Bacterial | Histidine-tRNA Ligase - metabolism | Bacterial Proteins - genetics | Arginine-tRNA Ligase - metabolism | RNA, Transfer, Amino Acyl - genetics | Cyanobacteria - enzymology | Amino Acid Motifs | Aspartate-tRNA Ligase - genetics | Glutamate-tRNA Ligase - metabolism | Glutamate-tRNA Ligase - genetics | Threonine-tRNA Ligase - metabolism | Evolution, Molecular | Proteins | Bacteria | Evolutionary biology | Molecular biology | Genomics
Journal Article
BMC Cancer, ISSN 1471-2407, 08/2014, Volume 14, Issue 1, p. 620
Journal Article
Medicine (United States), ISSN 0025-7974, 07/2012, Volume 91, Issue 4, pp. 206 - 211
Journal Article
Journal Article
Plant Cell Reports, ISSN 0721-7714, 07/2017, Volume 36, Issue 7, pp. 1053 - 1064
Key message An albinic rice is caused by mutation of threonyl-tRNA synthetase, which is essential for plant development by stabilizing of NEP and PEP gene... 
Oryza sativa | Chloroplast development | Plastid-encoded RNA polymerase | Chloroplast protein synthesis | ARABIDOPSIS-THALIANA | MITOCHONDRIA | POLYMERASE | EARLY LEAF DEVELOPMENT | PLANT SCIENCES | EMBRYO DEVELOPMENT | NUCLEUS | GENE-EXPRESSION | CHLOROPLAST RIBOSOME BIOGENESIS | TRANSCRIPTION MACHINERIES | MAIZE | Chloroplast Proteins - genetics | Plants, Genetically Modified - genetics | Oryza - metabolism | Gene Expression Regulation, Plant - genetics | Seedlings - genetics | Threonine-tRNA Ligase - genetics | Seedlings - enzymology | Oryza - enzymology | Chloroplasts - metabolism | Plant Proteins - genetics | Plastids - enzymology | Plants, Genetically Modified - metabolism | Oryza - genetics | Genes, Plant - genetics | Gene Expression Regulation, Plant - physiology | Plastids - genetics | Plastids - metabolism | Plant Proteins - metabolism | Mutation | Chloroplast Proteins - metabolism | Chloroplasts - genetics | Threonine-tRNA Ligase - metabolism | Seedlings - metabolism | Proteins | Chlorophyll | Yuan (China) | Analysis | Genes | Plant genetics | Genetically modified organisms | Protein biosynthesis | Genetic engineering | Aminoacyl-tRNA synthetases | Genetic translation | Transfer RNA | rRNA 16S | Fluorescence | Biosynthesis | Plants (organisms) | Accumulation | Leaves | Chloroplasts | Coding | Evolution | Physiology | Pep gene | Rice | Construction | tRNA | Splicing | Threonine-tRNA ligase | Cloning | rRNA 23S | Gene expression | Ribonucleic acids | Protein synthesis
Journal Article