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Molecular Immunology, ISSN 0161-5890, 2010, Volume 47, Issue 13, pp. 2170 - 2175
Journal Article
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, ISSN 1552-4868, 02/2011, Volume 157, Issue 1, pp. 33 - 44
Derivatives of cobalamin (vitamin B12) are required for activity of two enzymes in humans. Adenosylcobalamin is required for activity of mitochondrial... 
methylmalonic acidemia | vitamin B12 | cobalamin | homocystinuria | transcobalamin | Methylmalonic acidemia | Cobalamin | Transcobalamin | Homocystinuria | Vitamin B12 | HEREDITARY MEGALOBLASTIC-ANEMIA | HOMOCYSTINURIA CBLC | COMBINED METHYLMALONIC ACIDURIA | INTRINSIC-FACTOR GENE | METHIONINE SYNTHASE REDUCTASE | CBLB COMPLEMENTATION GROUP | METHYLCOBALAMIN DEFICIENCY | GENETICS & HEREDITY | TRANSCOBALAMIN-I HAPTOCORRIN | VITAMIN-B-12 METABOLISM | MOUSE GASTRULATION | Malabsorption Syndromes - diagnosis | Methylmalonic Acid - blood | Humans | Vitamin B 12 - analogs & derivatives | Hyperhomocysteinemia - metabolism | Malabsorption Syndromes - metabolism | Neonatal Screening | Amino Acid Metabolism, Inborn Errors - diagnosis | Methylmalonyl-CoA Mutase - metabolism | Amino Acid Metabolism, Inborn Errors - metabolism | Homocysteine - urine | Anemia, Megaloblastic | Proteinuria - diagnosis | Vitamin B 12 Deficiency - metabolism | Infant, Newborn | Methylmalonic Acid - urine | Cobamides - metabolism | Vitamin B 12 Deficiency - diagnosis | Metabolism, Inborn Errors - metabolism | Homocysteine - blood | Proteinuria - metabolism | Methylmalonyl-CoA Mutase - deficiency | Metabolism, Inborn Errors - diagnosis | Vitamin B 12 Deficiency - genetics | Hyperhomocysteinemia - diagnosis | Vitamin B 12 - metabolism | Thrombocytopenia | Urine | homocysteine | Enzymes | 5-Methyltetrahydrofolate-homocysteine S-methyltransferase | Anemia | adenosylcobalamin | Blood | Psychosis | Mitochondria | Dementia disorders | Complementation | Degeneration | Metabolic acidosis | Neutropenia
Journal Article
Circulation Research, ISSN 0009-7330, 03/2008, Volume 102, Issue 6, pp. 669 - 676
Sphingosine 1-phosphate (S1P), an abundant lipid mediator in plasma, regulates vascular and immune cells by activating S1P receptors. In this report, we... 
Plasma S1P gradient | Shear stress | S1P lyase (Sgpl) | Sphingosine 1-phosphate (S1P) | Sphingosine kinase (Sphk) | CELLS | sphingosine kinase (Sphk) | CARDIAC & CARDIOVASCULAR SYSTEMS | EXTRACELLULAR EXPORT | LIPID PHOSPHATE PHOSPHATASES | MECHANISMS | SPHINGOLIPIDS | plasma S1P gradient | KINASE-1 | SPHINGOSINE-1-PHOSPHATE | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | sphingosine 1-phosphate (S1P) | MICE | HEMATOLOGY | BLOOD | Lysophospholipids - metabolism | Whole-Body Irradiation | Liver - enzymology | Anemia - blood | Bone Marrow Cells - enzymology | Humans | Half-Life | Stress, Mechanical | Endothelium, Vascular - enzymology | Leukopenia - blood | RNA Interference | Time Factors | Bone Marrow Transplantation | Adenoviridae - genetics | Membrane Proteins - metabolism | Sphingosine - metabolism | Aldehyde-Lyases - genetics | Disease Models, Animal | Cell Line | Transduction, Genetic | Endothelial Cells - metabolism | Liver - metabolism | Mice, Inbred C57BL | Phosphotransferases (Alcohol Group Acceptor) - deficiency | Thrombocytopenia - immunology | Cells, Cultured | Anemia - chemically induced | Phosphotransferases (Alcohol Group Acceptor) - genetics | Lysophospholipids - blood | Antibodies, Monoclonal | Bone Marrow Cells - radiation effects | Phenylhydrazines | Thrombocytopenia - blood | Mice, Knockout | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Sphingosine - analogs & derivatives | Animals | Endothelium, Vascular - metabolism | Aldehyde-Lyases - metabolism | Cell Line, Tumor | Sphingosine - blood | Mice | Genetic Vectors | Phosphoric Monoester Hydrolases - metabolism | Endothelial Cells - enzymology | Bone Marrow Cells - metabolism | Platelet Glycoprotein GPIb-IX Complex - immunology | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 12/2010, Volume 207, Issue 13, pp. 2817 - 2830
Journal Article
Haematologica, ISSN 0390-6078, 07/2015, Volume 100, Issue 7, pp. 927 - 934
We previously demonstrated vast expansion of hypoxic areas in the leukemic microenvironment and provided a rationale for using hypoxia-activated prodrugs.... 
STEM-CELLS | INHIBITION | PR-104A | ACUTE MYELOGENOUS LEUKEMIA | BONE-MARROW | I TRIAL | KETO REDUCTASE 1C3 | HIF-1-ALPHA | HEMATOLOGY | CANCER-THERAPY | CHEMOTHERAPY | Recurrence | Humans | Middle Aged | Male | Antineoplastic Agents, Alkylating - administration & dosage | Carbonic Anhydrases - metabolism | Thrombocytopenia - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Anemia - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Bone Marrow - metabolism | Enterocolitis - genetics | Antigens, Neoplasm - metabolism | Bone Marrow - drug effects | Biomarkers - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications | Gene Expression | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Leukemia, Myeloid, Acute - pathology | Anemia - chemically induced | Hypoxia - complications | Thrombocytopenia - chemically induced | Thrombocytopenia - pathology | Nitrogen Mustard Compounds - adverse effects | Remission Induction | Hypoxia - pathology | Antineoplastic Agents, Alkylating - adverse effects | Enterocolitis - pathology | Prodrugs - administration & dosage | Hypoxia - drug therapy | Neutropenia - metabolism | Nitrogen Mustard Compounds - administration & dosage | Carbonic Anhydrases - genetics | Anemia - pathology | Leukemia, Myeloid, Acute - complications | Prodrugs - metabolism | Leukemia, Myeloid, Acute - drug therapy | Neutropenia - pathology | Adult | Female | Neutropenia - chemically induced | Neutropenia - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Carbonic Anhydrase IX | Enterocolitis - chemically induced | Antigens, Neoplasm - genetics | Nitroimidazoles - pharmacology | Thrombocytopenia - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Anemia - metabolism | Prodrugs - adverse effects | Hypoxia - genetics | Nitrogen Mustard Compounds - metabolism | Bone Marrow - pathology | Aged | Enterocolitis - metabolism | Antineoplastic Agents, Alkylating - metabolism | Leukemia, Myeloid, Acute - genetics
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 08/2015, Volume 13, Issue 8, pp. 1416 - 1427
Journal Article
Journal Article
Blood, ISSN 0006-4971, 04/2012, Volume 119, Issue 14, pp. 3333 - 3341
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 08/2016, Volume 36, Issue 8, pp. 1517 - 1524
Journal Article