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Blood, ISSN 0006-4971, 04/2006, Volume 107, Issue 8, pp. 3074 - 3080
Chronic graft-versus-host disease (GVHD) is a major limitation of successful allogeneic hematopoietic stem cell transplantation (HSCT). Extracorporeal... 
PREDICTORS | PEDIATRIC-PATIENTS | T-CELL LYMPHOMA | PHOTOPHERESIS THERAPY | MECHANISMS | PARAMETERS | COMBINATION | HEMATOLOGY | VERSUS-HOST-DISEASE | TRANSPLANTATION | LYMPHOCYTES | Anemia, Sickle Cell - pathology | Graft vs Host Disease - therapy | Eye - pathology | Liver - pathology | Immunosuppression - methods | Humans | Middle Aged | Child, Preschool | Male | Hematopoietic Stem Cell Transplantation - mortality | Anemia, Aplastic - therapy | Transplantation, Homologous | Breast Neoplasms - therapy | Immunosuppression - mortality | Anemia, Aplastic - mortality | Graft vs Host Disease - mortality | Immunosuppression - adverse effects | Photopheresis - mortality | Adult | Female | Photopheresis - methods | Retrospective Studies | Steroids - therapeutic use | Mouth Mucosa - pathology | Anemia, Aplastic - complications | Child | Graft vs Host Disease - etiology | Skin - pathology | Anemia, Aplastic - pathology | Steroids - adverse effects | Anemia, Sickle Cell - complications | Treatment Outcome | Drug Resistance - drug effects | Thrombocytopenia - pathology | Lymphoproliferative Disorders - pathology | Graft vs Host Disease - pathology | Anemia, Sickle Cell - therapy | Breast Neoplasms - complications | Disease-Free Survival | Lymphoproliferative Disorders - mortality | Anemia, Sickle Cell - mortality | Breast Neoplasms - pathology | Adolescent | Breast Neoplasms - mortality | Aged | Hematopoietic Stem Cell Transplantation - methods | Chronic Disease
Journal Article
Plastic and Reconstructive Surgery, ISSN 0032-1052, 1997, Volume 100, Issue 6, pp. 1377 - 1386
Children with a large vascular tumor and associated Kasabach-Merritt coagulopathy respond inconsistently to therapy and have a high mortality rate. For this... 
TRANEXAMIC ACID | SURGERY | EPSILON-AMINOCAPROIC ACID | PREDNISONE | THERAPY | SPINDLE-CELL HEMANGIOENDOTHELIOMA | VASCULAR MALFORMATIONS | FIBROBLAST GROWTH-FACTOR | ALPHA-INTERFERON | INFANCY | GIANT HEMANGIOMA | Thoracic Neoplasms - therapy | Hemangioendothelioma - diagnosis | Blood Vessels - pathology | Humans | Retroperitoneal Neoplasms - therapy | Infant | Male | Antineoplastic Agents - therapeutic use | Recombinant Proteins | Ecchymosis - pathology | Basement Membrane - pathology | Retroperitoneal Neoplasms - diagnosis | Thrombocytopenia - complications | Hemangioendothelioma - pathology | Skin Neoplasms - diagnosis | Female | Retrospective Studies | Retroperitoneal Neoplasms - pathology | Infant, Newborn | Skin Neoplasms - pathology | Hemangioendothelioma - therapy | Skin Neoplasms - therapy | Adipose Tissue - pathology | Head and Neck Neoplasms - therapy | Interferon-alpha - therapeutic use | Thoracic Neoplasms - pathology | Retroperitoneal Neoplasms - complications | Hemangioma - diagnosis | Microscopy, Electron | Thrombocytopenia - pathology | Syndrome | Head and Neck Neoplasms - pathology | Skin Neoplasms - complications | Lymphoid Tissue - pathology | Magnetic Resonance Imaging | Purpura, Thrombocytopenic - pathology | Thoracic Neoplasms - diagnosis | Thoracic Neoplasms - complications | Interferon alpha-2 | Endothelium, Vascular - pathology | Head and Neck Neoplasms - complications | Head and Neck Neoplasms - diagnosis | Thrombocytopenia - diagnosis | Hemosiderin - analysis | Edema - pathology | Hemangioendothelioma - complications
Journal Article
Best Practice & Research: Clinical Haematology, ISSN 1521-6926, 2015, Volume 28, Issue 4, pp. 193 - 199
Abstract Unusual clinical manifestations and associations with auto-immunity or other systemic disorders are uncommon clinical features of hairy cell leukemia... 
Hematology, Oncology and Palliative Medicine | Rare manifestations | Clinical features | Hairy cell leukemia (HCL) | DIAGNOSIS | LYMPHADENOPATHY | COMPLICATIONS | HEMATOLOGY | Bone and Bones - pathology | Liver - pathology | Lymph Nodes - pathology | Humans | Male | Behcet Syndrome - pathology | Splenomegaly - pathology | Antiphospholipid Syndrome - complications | Thrombocytopenia - complications | Splenomegaly - complications | Splenomegaly - diagnosis | Liver - immunology | Anemia, Hemolytic, Autoimmune - pathology | Lymphatic Diseases - diagnosis | Anemia, Hemolytic, Autoimmune - diagnosis | Female | B-Lymphocytes - pathology | Leukemia, Hairy Cell - pathology | Skin - pathology | Skin - immunology | Leukemia, Hairy Cell - immunology | Antiphospholipid Syndrome - diagnosis | Lymphatic Diseases - immunology | Splenomegaly - immunology | Thrombocytopenia - immunology | Behcet Syndrome - complications | Lymphatic Diseases - complications | Anemia, Hemolytic, Autoimmune - complications | Lymph Nodes - immunology | Thrombocytopenia - pathology | Leukemia, Hairy Cell - diagnosis | Antiphospholipid Syndrome - immunology | B-Lymphocytes - drug effects | Leukemia, Hairy Cell - complications | Antiphospholipid Syndrome - pathology | Anemia, Hemolytic, Autoimmune - immunology | Sex Factors | Lymphatic Diseases - pathology | Thrombocytopenia - diagnosis | Behcet Syndrome - diagnosis | Bone and Bones - immunology | Behcet Syndrome - immunology | Leukemia, Hairy cell
Journal Article
Toxicon, ISSN 0041-0101, 05/2015, Volume 98, pp. 89 - 97
Though systemic and local manifestations of snakebite are considered serious, the relevance of oxidative stress in viper bite pathology is largely denied.... 
Hyaluronidase | Oxidative stress | Damage associated molecular patterns (DAMPs) | SVMPs | Secondary complications | Viper venom | Damage associated molecular patterns | DAMPs | ACUTE KIDNEY INJURY | AMINOPEPTIDASE ACTIVITIES | SRI-LANKA | RENAL-FUNCTION | DABOIA-RUSSELII | SNAKE-VENOM HYALURONIDASE | PHOSPHOLIPASES A | OVERLOOKED ISSUES | LOCAL TISSUE-DAMAGE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | Damage associated molecular patterns (DAMPS) | DURISSUS-TERRIFICUS ENVENOMATION | Inflammation - pathology | Urogenital Abnormalities - etiology | Kidney - pathology | Humans | Homeostasis | Hemorrhage - prevention & control | Antivenins - therapeutic use | Necrosis - pathology | Snake Bites - pathology | Inflammation - drug therapy | Urogenital Abnormalities - prevention & control | Hemorrhage - etiology | Hypopituitarism - pathology | Hypopituitarism - prevention & control | Snake Bites - complications | Disease Models, Animal | Snake Bites - drug therapy | Thrombocytopenia - etiology | Hypopituitarism - etiology | Thrombocytopenia - pathology | Inflammation - etiology | Necrosis - prevention & control | Viper Venoms - toxicity | Antioxidants - therapeutic use | Urogenital Abnormalities - pathology | Animals | Kidney - abnormalities | Necrosis - etiology | Thrombocytopenia - prevention & control | Oxidative Stress - drug effects | Hemorrhage - pathology | Poisonous snakes | Antioxidants | Enzymes | Inflammation | Index Medicus | Stresses | Pathology | Turbulence | Fluid dynamics | Abnormalities | Disturbances | Exploration | Dampness
Journal Article
Human Mutation, ISSN 1059-7794, 04/2014, Volume 35, Issue 4, pp. 478 - 485
Journal Article
The Journal of Infectious Diseases, ISSN 0022-1899, 6/2013, Volume 207, Issue 12, pp. 1909 - 1921
Crimean-Congo hemorrhagic fever (CCHF) is a widely distributed viral hemorrhagic fever characterized by rapid onset of flu-like symptoms often followed by... 
Pathology | Disease models | Interleukins | Tissue samples | Crimean Congo hemorrhagic fever virus | Viral diseases | Viruses | Infections | Platelets | Dosage | pathology | coagulopathy | proinflammatory response | thrombocytopenia | CCHFV | interferon α/β receptor knockout mice | CELLS | INFECTIOUS DISEASES | PREDICTOR | MICROBIOLOGY | MODEL | IMMUNOLOGY | PATHOGENESIS | TRANSMISSION | REPLICATION | DISSEMINATED INTRAVASCULAR COAGULATION | beta receptor knockout mice | CCHF VIRUS | AFRICAN | interferon alpha | Liver - virology | Spleen - virology | Liver - pathology | Viremia | Hemorrhagic Fever, Crimean - complications | Humans | Liver Failure, Acute - virology | Viral Load | Blood Coagulation Disorders - virology | Hemorrhagic Fever, Crimean - immunology | Receptor, Interferon alpha-beta - genetics | Spleen - pathology | Disease Models, Animal | Hemorrhagic Fever Virus, Crimean-Congo - physiology | Cytokines - metabolism | Lymphoid Tissue - virology | Mice, Inbred C57BL | Thrombocytopenia - immunology | Hemorrhagic Fever Virus, Crimean-Congo - immunology | Thrombocytopenia - pathology | Thrombocytopenia - virology | Disease Progression | Mice, Knockout | Lymphoid Tissue - pathology | Animals | Hemorrhagic Fever, Crimean - pathology | Blood Coagulation Disorders - pathology | Receptor, Interferon alpha-beta - immunology | Blood Coagulation Disorders - immunology | Liver Failure, Acute - immunology | Liver Failure, Acute - pathology | Chemokines - metabolism | Mice | Major and Brief Reports | β receptor knockout mice | interferon α
Journal Article
Haematologica, ISSN 0390-6078, 07/2015, Volume 100, Issue 7, pp. 927 - 934
We previously demonstrated vast expansion of hypoxic areas in the leukemic microenvironment and provided a rationale for using hypoxia-activated prodrugs.... 
STEM-CELLS | INHIBITION | PR-104A | ACUTE MYELOGENOUS LEUKEMIA | BONE-MARROW | I TRIAL | KETO REDUCTASE 1C3 | HIF-1-ALPHA | HEMATOLOGY | CANCER-THERAPY | CHEMOTHERAPY | Recurrence | Humans | Middle Aged | Male | Antineoplastic Agents, Alkylating - administration & dosage | Carbonic Anhydrases - metabolism | Thrombocytopenia - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Anemia - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Bone Marrow - metabolism | Enterocolitis - genetics | Antigens, Neoplasm - metabolism | Bone Marrow - drug effects | Biomarkers - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - complications | Gene Expression | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Leukemia, Myeloid, Acute - pathology | Anemia - chemically induced | Hypoxia - complications | Thrombocytopenia - chemically induced | Thrombocytopenia - pathology | Nitrogen Mustard Compounds - adverse effects | Remission Induction | Hypoxia - pathology | Antineoplastic Agents, Alkylating - adverse effects | Enterocolitis - pathology | Prodrugs - administration & dosage | Hypoxia - drug therapy | Neutropenia - metabolism | Nitrogen Mustard Compounds - administration & dosage | Carbonic Anhydrases - genetics | Anemia - pathology | Leukemia, Myeloid, Acute - complications | Prodrugs - metabolism | Leukemia, Myeloid, Acute - drug therapy | Neutropenia - pathology | Adult | Female | Neutropenia - chemically induced | Neutropenia - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Carbonic Anhydrase IX | Enterocolitis - chemically induced | Antigens, Neoplasm - genetics | Nitroimidazoles - pharmacology | Thrombocytopenia - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Anemia - metabolism | Prodrugs - adverse effects | Hypoxia - genetics | Nitrogen Mustard Compounds - metabolism | Bone Marrow - pathology | Aged | Enterocolitis - metabolism | Antineoplastic Agents, Alkylating - metabolism | Leukemia, Myeloid, Acute - genetics
Journal Article
Journal Article
Blood, ISSN 0006-4971, 08/2006, Volume 108, Issue 4, pp. 1158 - 1164
We present results of 2 similarly designed but separate phase 2 studies involving single-agent lenalidomide (CC-5013, Revlimid) in a total of 68 patients with... 
MULTIPLE-MYELOMA | GROWTH-FACTOR-BETA | LOW-DOSE THALIDOMIDE | CC-5013 | MYELOPROLIFERATIVE-DISORDERS | ANGIOGENESIS | ANALOGS | MUTATION | CELL TRANSPLANTATION | MYELODYSPLASTIC-SYNDROMES | HEMATOLOGY | Humans | Male | Primary Myelofibrosis - pathology | Neovascularization, Pathologic - complications | Primary Myelofibrosis - blood | Thrombocytopenia - genetics | Thalidomide - analogs & derivatives | Anemia - genetics | Anemia - drug therapy | Anemia, Myelophthisic - genetics | Time Factors | Splenomegaly - blood | Neutropenia - blood | Thalidomide - adverse effects | Primary Myelofibrosis - complications | Splenomegaly - genetics | Administration, Oral | Anemia, Myelophthisic - pathology | Thrombocytopenia - chemically induced | Thalidomide - administration & dosage | Thrombocytopenia - pathology | Remission Induction | Neovascularization, Pathologic - drug therapy | Anemia, Myelophthisic - complications | Sequence Deletion | Splenomegaly - drug therapy | Anemia - blood | Anemia - pathology | Splenomegaly - pathology | Anemia, Myelophthisic - blood | Neovascularization, Pathologic - blood | Neovascularization, Pathologic - pathology | Janus Kinase 2 | Splenomegaly - complications | Protein-Tyrosine Kinases - genetics | Thrombocytopenia - drug therapy | Neutropenia - pathology | Adult | Female | Neutropenia - chemically induced | Neutropenia - genetics | Primary Myelofibrosis - drug therapy | Proto-Oncogene Proteins - genetics | Thrombocytopenia - blood | Anemia, Myelophthisic - drug therapy | Point Mutation | Anemia - complications | Primary Myelofibrosis - genetics | Platelet Count | Neovascularization, Pathologic - genetics | Aged | Hemoglobins - analysis
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2010, Volume 5, Issue 2, p. e9441
Hemophagocytic lymphohistiocytosis (HLH) is a hyper-inflammatory clinical syndrome associated with neoplastic disorders especially lymphoma, autoimmune... 
DIAGNOSIS | MUTANT MICE | MACROPHAGES | MALIGNANT HISTIOCYTOSIS | IN-VIVO | GENES | BIOLOGY | SALMONELLA-TYPHIMURIUM | INFECTION | IRON-DEFICIENCY | SPECTRUM | Lymphohistiocytosis, Hemophagocytic - etiology | Inflammation - pathology | Liver - pathology | Lymphohistiocytosis, Hemophagocytic - pathology | Typhoid Fever - complications | Humans | Bone Marrow Diseases - pathology | Splenomegaly - pathology | Mice, Inbred Strains | Thrombocytopenia - pathology | Salmonella Infections, Animal - complications | Host-Pathogen Interactions | Animals | Typhoid Fever - microbiology | Ferritins - blood | Salmonella typhi - physiology | Salmonella Infections, Animal - microbiology | Female | Mice | Chronic Disease | Fever - pathology | Disease Models, Animal | Lymphohistiocytosis, Hemophagocytic - blood | Anemia | Analysis | Typhoid fever | Lymphomas | Macrophages | Health aspects | Diseases | Water-borne diseases | Salmonella | Splenomegaly | Disease | Laboratories | Pathogenesis | Disorders | Chronic infection | Viruses | Iron | Infections | Veterinary medicine | Fungi | Lymphocytes | Rodents | Bone marrow | Bacteria | Spleen | Thrombocytopenia | Protozoa | Lymphatic system | Cytokines | Hematology | Developmental biology | Body temperature | Inflammation | Typhoid | Histiocytosis | Lymphoma | Fever | Pathology | Lipoproteins | Infectious diseases | Mutation | Lymphocytosis | Metabolic disorders | Viral infections
Journal Article
The American Journal of Pathology, ISSN 0002-9440, 2004, Volume 164, Issue 3, pp. 1115 - 1127
Journal Article