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Seminars in immunopathology, ISSN 1863-2300, 2011, Volume 34, Issue 1, pp. 43 - 62
The interaction of coagulation factors with the perivascular environment affects the development of disease in ways that extend beyond their traditional roles... 
Autoimmunity | Complement receptor 3 | Multiple sclerosis | Stroke | Alzheimer’s disease | Internal Medicine | Macrophages | Blood brain barrier | Inflammatory disease | Microglia | Biomedicine | Immunology | Rheumatoid arthritis | CD11b/CD18 | Atherosclerosis | Plasminogen | Anticoagulant therapy | Alzheimer's disease | ALZHEIMERS-DISEASE | IMMUNOLOGY | PATHOLOGY | GAMMA-C-DOMAIN | BINDING-SITE | CENTRAL-NERVOUS-SYSTEM | MULTIPLE-SCLEROSIS LESIONS | CRYSTAL-STRUCTURE | BLOOD-BRAIN-BARRIER | INTEGRIN ALPHA(M)BETA | PROTEASE-ACTIVATED RECEPTORS | PERIPHERAL ARTERIAL-DISEASE | Colitis - genetics | Humans | Brain Injuries - metabolism | Arthritis, Rheumatoid - metabolism | Bacterial Infections - genetics | Inflammation - metabolism | Blood Coagulation - immunology | Muscular Dystrophy, Duchenne - immunology | Alzheimer Disease - immunology | Fibrinogen - immunology | Thromboplastin - immunology | Pulmonary Fibrosis - immunology | Vascular Diseases - genetics | Brain Injuries - genetics | Thrombin - genetics | Kidney Diseases - immunology | Arthritis, Rheumatoid - genetics | Neoplasms - immunology | Colitis - metabolism | Muscular Dystrophy, Duchenne - genetics | Bacterial Infections - metabolism | Neoplasms - metabolism | Pulmonary Fibrosis - genetics | Spinal Cord Injuries - genetics | Kidney Diseases - genetics | Stroke - genetics | Brain Injuries - immunology | Neoplasms - genetics | Bacterial Infections - immunology | Pulmonary Fibrosis - metabolism | Colitis - immunology | Thrombin - immunology | Stroke - immunology | Kidney Diseases - metabolism | Multiple Sclerosis - metabolism | Vascular Diseases - immunology | Spinal Cord Injuries - metabolism | Multiple Sclerosis - genetics | Inflammation - immunology | Fibrinogen - genetics | Stroke - metabolism | Animals | Thromboplastin - genetics | Alzheimer Disease - metabolism | Fibrinogen - metabolism | Inflammation - genetics | Multiple Sclerosis - immunology | Blood Coagulation - genetics | Spinal Cord Injuries - immunology | Muscular Dystrophy, Duchenne - metabolism | Thrombin - metabolism | Thromboplastin - metabolism | Alzheimer Disease - genetics | Arthritis, Rheumatoid - immunology | Vascular Diseases - metabolism | Nervous system diseases | Bacterial infections | Oncology, Experimental | Thrombin | Inflammation | Anticoagulants (Medicine) | Research | Rheumatoid factor | Fibrin | Fibrinogen | Genetic research | Colitis | Cancer | Traumatic brain injury | Coagulation | Tissue factor | hemostasis | Spinal cord injury | Inflammatory diseases | Kidney | Signal transduction | Duchenne's muscular dystrophy | Neurodegenerative diseases | Therapeutic applications | Thrombosis | Coagulation factors | Infection | Molecular modelling | Fibrosis | Brain injury
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 03/2014, Volume 34, Issue 3, pp. 487 - 498
Low-density lipoprotein receptor–related protein-1 (LRP1) is a large endocytic and signaling receptor that is widely expressed. In the liver, LRP1 plays an... 
Extracellular matrix | LRP1 | fVIII | Elastin | Aneurysm | aneurysm | GROWTH-FACTOR-RECEPTOR | FACTOR-VIII | DEPENDENT PHOSPHATIDYLINOSITOL 3-KINASE | MUSCLE-CELL PROLIFERATION | elastin | VON-WILLEBRAND-FACTOR | BLOOD-BRAIN-BARRIER | ALPHA-2-MACROGLOBULIN RECEPTOR | APOLIPOPROTEIN-E | PLASMINOGEN-ACTIVATOR | UROKINASE RECEPTOR | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | extracellular matrix | Muscle, Smooth, Vascular - metabolism | Humans | Low Density Lipoprotein Receptor-Related Protein-1 - chemistry | Extracellular Matrix - metabolism | Low Density Lipoprotein Receptor-Related Protein-1 - physiology | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | Receptors, LDL - deficiency | Models, Animal | Lipoproteins, LDL - metabolism | Peptide Hydrolases - metabolism | von Willebrand Factor - metabolism | Elastin - metabolism | Receptors, LDL - genetics | Signal Transduction | Liver - metabolism | Transforming Growth Factor beta - physiology | Models, Molecular | Organ Specificity | Atherosclerosis - metabolism | Endocytosis - physiology | Mice, Knockout | Tumor Suppressor Proteins - physiology | Macrophages - metabolism | Platelet-Derived Growth Factor - metabolism | Animals | Protein Conformation | Mice | Blood Coagulation - physiology | Factor VIII - metabolism | Receptors, LDL - physiology | Thromboplastin - metabolism | Aneurysm - prevention & control
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 02/2011, Volume 286, Issue 7, pp. 5756 - 5767
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 05/2009, Volume 296, Issue 5, pp. 1675 - 1682
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 11/2017, Volume 117, Issue 11, pp. 2125 - 2134
Abstract Objective  Alveolar macrophages play a key role in the development and resolution of acute respiratory distress syndrome (ARDS), modulating the... 
Blood Cells, Inflammation and Infection | Acute respiratory distress syndrome | Acute lung injury | Heparin | Alveolarmacrophages | Anti-coagulants | ANTICOAGULANTS | alveolar macrophages | STIMULATED HUMAN MONOCYTES | RESOLUTION | RANDOMIZED CONTROLLED-TRIAL | anti-coagulants | acute lung injury | RESPIRATORY-DISTRESS-SYNDROME | heparin | acute respiratory distress syndrome | ANTITHROMBIN-III | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | EXPRESSION | TISSUE FACTOR | EPIDEMIOLOGY | SEVERE SEPSIS | Tumor Necrosis Factor-alpha - metabolism | Macrophages, Alveolar - pathology | Anticoagulants - administration & dosage | Fibrin Fibrinogen Degradation Products - metabolism | Pneumonia - pathology | Pneumonia - prevention & control | Heparin - administration & dosage | Male | NF-kappa B - metabolism | Acute Lung Injury - blood | Lipopolysaccharides | Pneumonia - chemically induced | Inflammation Mediators - metabolism | Pulmonary Edema - prevention & control | Anti-Inflammatory Agents - administration & dosage | Pneumonia - blood | Pulmonary Edema - pathology | Acute Lung Injury - drug therapy | Lung - metabolism | Interleukin-6 - metabolism | Pulmonary Edema - metabolism | Neutrophil Infiltration - drug effects | Disease Models, Animal | Peptide Hydrolases - metabolism | Lung - pathology | Administration, Inhalation | Acute Lung Injury - pathology | Rats, Sprague-Dawley | Animals | Acute Lung Injury - chemically induced | Blood Coagulation - drug effects | Signal Transduction - drug effects | Macrophages, Alveolar - drug effects | Lung - drug effects | Antithrombin III - metabolism | Macrophages, Alveolar - metabolism | Thromboplastin - metabolism | Transforming Growth Factor beta - metabolism | Nebulizers and Vaporizers
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