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Journal Article
FEBS Journal, ISSN 1742-464X, 12/2007, Volume 274, Issue 24, pp. 6365 - 6377
Angiogenic switch in renal cell carcinoma (RCC) is attributed to the inactivation of the von Hippel–Lindau tumor suppressor, stabilization of hypoxia inducible... 
thrombospondin | renal cancer | angiogenesis | calcium metabolism | Calcium metabolism | Angiogenesis | Renal cancer | Thrombospondin | PATHWAYS | METASTASIS | LIGAND BIOLOGICAL AXIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CANCER | WILMS-TUMOR | IN-VIVO | GENES | INHIBITOR | TUMOR-GROWTH | EXPRESSION | Immunohistochemistry | Cell Proliferation | Thrombospondin 1 - secretion | Calcium - metabolism | Humans | Rats, Inbred F344 | Corneal Neovascularization - genetics | Neovascularization, Pathologic - pathology | Transfection | Thrombospondin 1 - genetics | Egtazic Acid - analogs & derivatives | Female | TRPC Cation Channels - genetics | Carcinoma, Renal Cell - blood supply | Cell Line | Carcinoma, Renal Cell - pathology | Mice, Inbred C57BL | COP-Coated Vesicles - drug effects | COP-Coated Vesicles - metabolism | Rats | Chelating Agents - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Animals | Corneal Neovascularization - metabolism | Egtazic Acid - pharmacology | Fluorescent Antibody Technique | TRPC Cation Channels - metabolism | Cell Line, Tumor | Kidney Neoplasms - pathology | Neovascularization, Pathologic - genetics | Mice | Neovascularization, Pathologic - metabolism | Thrombospondin 1 - metabolism | Calcium - pharmacokinetics | Corneal Neovascularization - pathology | Kidney Neoplasms - blood supply | Physiological aspects | Carcinoma, Renal cell | Neovascularization | Endothelial growth factors | Biochemistry | Inhibitor drugs | Kidney diseases | Cellular biology | Cancer | Tumors
Journal Article
Cell, ISSN 0092-8674, 2005, Volume 120, Issue 3, pp. 421 - 433
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 37, pp. 15352 - 15368
Bone morphogenetic proteins (BMPs) regulate diverse cellular responses during embryogenesis and in adulthood including cell differentiation, proliferation, and... 
SYSTEM | TGF-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | INVOLVEMENT | FOLLICLE-STIMULATING-HORMONE | RECEPTOR | SECRETION | DYNAMIC REGULATION | STATISTICAL-MODEL | ACTIVIN | Bone Morphogenetic Protein 2 - blood | Recombinant Fusion Proteins - isolation & purification | Thrombospondin 1 - secretion | Pituitary Gland - metabolism | Sheep, Domestic | Bone Morphogenetic Protein 4 - genetics | Humans | Bone Morphogenetic Protein 4 - antagonists & inhibitors | Pituitary Gland - secretion | Bone Morphogenetic Protein 4 - metabolism | Recombinant Fusion Proteins - metabolism | Bone Morphogenetic Protein 4 - blood | Thrombospondin 1 - isolation & purification | Thrombospondin 1 - chemistry | Bone Morphogenetic Protein 2 - metabolism | Female | Protein Interaction Domains and Motifs | Genes, Reporter | Recombinant Proteins - metabolism | Bone Morphogenetic Protein 2 - genetics | Cell Line | Response Elements | Bone Morphogenetic Protein 2 - antagonists & inhibitors | Cells, Cultured | Computational Biology | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Fusion Proteins - chemistry | Sequence Homology, Amino Acid | Animals | Animals, Inbred Strains | Mice | Thrombospondin 1 - metabolism | Pituitary Gland - cytology | Life Sciences | Other | thrombospondin | C3H10T1 | bone morphogenetic protein antagonist | 2 cells | bone morphogenetic protein (BMP) | surface plasmon resonance (SPR) | pituitary gland | structural model | Cell Biology
Journal Article
Leukemia, ISSN 0887-6924, 2002, Volume 16, Issue 5, pp. 911 - 919
Initial work has shown that clonal B cells from B-chronic lymphocytic leukemia (B-CLL) are able to synthesize pro-angiogenic molecules. In this study, our goal... 
TSP-1 | Vascular factors | VEGF | B-CLL | Receptors, Vascular Endothelial Growth Factor | Vascular Endothelial Growth Factor A | Lymphokines - secretion | Thrombospondin 1 - secretion | Vascular Endothelial Growth Factors | Humans | Receptors, Cell Surface | RNA, Messenger - metabolism | Endothelial Growth Factors - secretion | Vascular Endothelial Growth Factor Receptor-1 | Receptors, Growth Factor - genetics | Endoglin | Endothelial Growth Factors - analysis | B-Lymphocytes - secretion | Fibroblast Growth Factor 2 - analysis | Fibroblast Growth Factor 2 - secretion | Germ-Line Mutation | Vascular Cell Adhesion Molecule-1 - genetics | B-Lymphocytes - pathology | Tumor Cells, Cultured | B-Lymphocytes - metabolism | Autocrine Communication | Peptide Fragments - secretion | Proto-Oncogene Proteins - genetics | Clone Cells - secretion | Collagen - secretion | Clone Cells - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | Thrombospondin 1 - analysis | Peptide Fragments - analysis | Interferon-alpha - analysis | Clone Cells - pathology | Receptors, Thrombin - genetics | Angiogenesis Inhibitors - biosynthesis | Lymphokines - analysis | Receptor Protein-Tyrosine Kinases - genetics | Interferon-alpha - secretion | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | Receptors, Growth Factor - biosynthesis | Endostatins | Collagen - analysis | Growth Substances - biosynthesis | Antigens, CD | Cohort Studies | Chronic lymphocytic leukemia | Cancer cells | Physiological aspects | Development and progression | Research | Neovascularization | Growth factors
Journal Article
PROSTATE, ISSN 0270-4137, 12/2001, Volume 49, Issue 4, pp. 293 - 305
BACKGROUND. Prostate cells secrete many molecules capable of regulating angiogenesis; however, which of these actually function as essential regulators of... 
IN-VITRO EXPRESSION | NUDE-MICE | prostate stroma | neovascularization | TUMOR-SUPPRESSOR GENE | THERAPEUTIC IMPLICATIONS | MICROVESSEL DENSITY | RADICAL PROSTATECTOMY | FACTOR VEGF EXPRESSION | prostate cancer | CAPILLARY ARCHITECTURE | INHIBITS ANGIOGENESIS | ENDOCRINOLOGY & METABOLISM | UROLOGY & NEPHROLOGY | antiangiogenesis | benign prostatic hyperplasia | CANCER CELL-LINES | Immunohistochemistry | Prostatic Neoplasms - metabolism | Vascular Endothelial Growth Factor A | Endothelial Growth Factors - metabolism | Prostatic Hyperplasia - pathology | Epithelial Cells - metabolism | Lymphokines - secretion | Thrombospondin 1 - secretion | Vascular Endothelial Growth Factors | Humans | Male | Prostatic Neoplasms - secretion | Prostate - metabolism | Endothelial Growth Factors - secretion | Epithelial Cells - secretion | Fibroblast Growth Factor 2 - secretion | Fibroblast Growth Factor 2 - metabolism | Lymphokines - metabolism | Adult | Neovascularization, Pathologic - physiopathology | Prostate - blood supply | Prostate - secretion | Fibroblast Growth Factor 2 - physiology | Tumor Cells, Cultured | Endothelial Growth Factors - physiology | Prostatic Neoplasms - blood supply | Enzyme-Linked Immunosorbent Assay | Thrombospondin 1 - physiology | Lymphokines - physiology | Blotting, Western | Prostatic Hyperplasia - metabolism | Neovascularization, Physiologic - physiology | Adolescent | Neovascularization, Pathologic - metabolism | Thrombospondin 1 - metabolism
Journal Article