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physiological aspects (6) 6
rats, sprague-dawley (6) 6
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thromboxane-prostanoid receptors (6) 6
up-regulation (6) 6
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cells, cultured (5) 5
dose-response relationship, drug (5) 5
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muscle contraction - drug effects (5) 5
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prostaglandin (5) 5
rats, inbred shr (5) 5
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acetylcholine - pharmacology (4) 4
aging (4) 4
airway smooth muscle (4) 4
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cyclooxygenase 2 - metabolism (4) 4
cyclooxygenase-2 (4) 4
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activation (3) 3
afferent arterioles (3) 3
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angiotensin ii receptor subtypes (3) 3
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aspirin (3) 3
biochemistry (3) 3
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PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, pp. e60475 - e60475
Journal Article
THROMBOSIS AND HAEMOSTASIS, ISSN 0340-6245, 11/2018, Volume 118, Issue 11, pp. 1982 - 1996
Objective Activation of thromboxane A(2) synthase (TXAS)/thromboxane A(2) (TXA(2))/thromboxane prostanoid (TP) receptor leads to arterial constriction,... 
ischaemia/reperfusion injury | ACTIVATION | MESENTERIC-ARTERIES | NITRIC-OXIDE SYNTHASE | MYOCARDIAL-ISCHEMIA | KNOCKOUT MICE | thromboxane A synthase | ISCHEMIA-REPERFUSION INJURY | RAT HEARTS | ANGINA | thromboxane prostanoid receptor | aspirin | thromboxane A | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | CORONARY-ARTERY SPASM
Journal Article
RESPIRATORY RESEARCH, ISSN 1465-993X, 03/2006, Volume 7
Background: Cysteine-containing leukotrienes (cysteinyl-LTs) are pivotal inflammatory mediators that play important roles in the pathophysiology of asthma,... 
SIGNAL-TRANSDUCTION | CYSTEINYL LEUKOTRIENES | EPITHELIAL-CELLS | RESPIRATORY SYSTEM | PROTEIN-COUPLED RECEPTORS | ASTHMA | DIFFERENTIATED U937 CELLS | HUMAN LUNG PARENCHYMA | BINDING-SITES | KINASE ACTIVATION | THROMBOXANE PROSTANOID RECEPTOR
Journal Article
Kidney International, ISSN 0085-2538, 07/2013, Volume 84, Issue 1, pp. 54 - 63
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2013, Volume 441, Issue 2, pp. 393 - 398
The prothrombotic mediator thromboxane A is derived from arachidonic acid metabolism through the cyclooxygenase and thromboxane synthase pathways, and... 
Eicosanoids | Thromboxane prostanoid receptor | Inflammation | Smooth muscle cells | Endothelial cells | ACTIVATION | PROSTACYCLIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | ATHEROSCLEROSIS | RATS | PROLIFERATION | DEFICIENT MICE | ASPIRIN | IN-VITRO | BIOPHYSICS | GROWTH-FACTOR | C-Reactive Protein - antagonists & inhibitors | Gene Expression - drug effects | Human Umbilical Vein Endothelial Cells - metabolism | Muscle, Smooth, Vascular - metabolism | Humans | Endothelium, Vascular - drug effects | Coronary Vessels - metabolism | RNA, Messenger - biosynthesis | Intercellular Adhesion Molecule-1 - biosynthesis | Prostaglandins F - secretion | RNA, Messenger - antagonists & inhibitors | Receptors, Thromboxane - antagonists & inhibitors | Serum Amyloid P-Component - biosynthesis | C-Reactive Protein - biosynthesis | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Serum Amyloid P-Component - antagonists & inhibitors | Muscle, Smooth, Vascular - drug effects | Coronary Vessels - drug effects | Human Umbilical Vein Endothelial Cells - drug effects | Thromboxane-A Synthase - antagonists & inhibitors | Cells, Cultured | Muscle, Smooth, Vascular - cytology | Tumor Necrosis Factor-alpha - pharmacology | Coronary Vessels - cytology | Endothelium, Vascular - metabolism | Thromboxane A2 - physiology | 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - pharmacology | Cell Proliferation - drug effects | Smooth muscle | Endothelium | Index Medicus | VEINS | ARACHIDONIC ACID | CELL PROLIFERATION | 60 APPLIED LIFE SCIENCES | CONCENTRATION RATIO | ARTERIOSCLEROSIS | INSULIN | GROWTH FACTORS | HYPERTROPHY | POLYMERASE CHAIN REACTION | MESSENGER-RNA | CORONARIES | ENZYMES | INFLAMMATION | RECEPTORS | MUSCLES | Medicin och hälsovetenskap | Medicinsk bioteknologi (inriktn. mot cellbiologi (inkl. stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Medicinsk bioteknologi
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, ISSN 0363-6135, 12/2007, Volume 293, Issue 6, pp. H3448 - H3455
We investigated whether A(3) adenosine receptor (A(3)AR) is involved in endothelium-mediated contraction through cyclooxygenases (COXs) with the use of... 
endothelium | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | SPONTANEOUSLY HYPERTENSIVE-RATS | DEPENDENT CONTRACTIONS | GUINEA-PIG | CYCLOOXYGENASE | thromboxane prostanoid receptors | MAST-CELL | cyclooxygenases | HUMAN GALLBLADDER | A knockout | NITRIC-OXIDE | contraction | PERIPHERAL VASCULAR DISEASE | thromboxane A pathway | THROMBOXANE A | DYSFUNCTION | EXPRESSION
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 12/2007, Volume 293, Issue 6, pp. 3448 - 3455
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 11/2011, Volume 301, Issue 5, pp. 675 - 682
Epoxyeicosatrienoic acid (EET) and thromboxane A2 are arachidonic acid derivatives. The former has initially been defined as an epithelium-derived... 
Trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid | Thromboxane a | U-46619 | Airway smooth muscle | N-(methylsulfonyl)-2-(2-propynyloxy)-benzenehexanamide | Thromboxane-prostanoid-receptor | PHYSIOLOGY | thromboxane-prostanoid-receptor | EPOXYGENASE METABOLITES | airway smooth muscle | SOLUBLE EPOXIDE HYDROLASE | INHIBITION | RESPIRATORY SYSTEM | trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid | CHANNEL ACTIVATION | thromboxane A | PPAR-GAMMA | TARGETS | VASODILATION | AIRWAY SMOOTH-MUSCLE | CORONARY ARTERIOLES | K+ CHANNEL | Arachidonic Acid - metabolism | Humans | Bronchi - drug effects | Muscle, Smooth - drug effects | 8,11,14-Eicosatrienoic Acid - analogs & derivatives | Urea - analogs & derivatives | Receptors, Thromboxane - antagonists & inhibitors | Muscle, Smooth - physiology | Bronchi - physiology | 8,11,14-Eicosatrienoic Acid - pharmacology | Myocytes, Smooth Muscle - drug effects | Bronchi - cytology | Myocytes, Smooth Muscle - cytology | Epoxy Compounds | Guinea Pigs | Signal Transduction | Electrophoresis, Polyacrylamide Gel | Cells, Cultured | Eicosapentaenoic Acid - metabolism | Myocytes, Smooth Muscle - physiology | Rats | Muscle Tonus - drug effects | Blotting, Western | Thromboxane A2 - metabolism | Animals | Receptors, Prostaglandin E - agonists | Receptors, Thromboxane - agonists | Receptors, Prostaglandin E - antagonists & inhibitors | 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - pharmacology | Fluorescent Antibody Technique | Benzoates - pharmacology | Receptors, Thromboxane - metabolism | Mice | Epoxide Hydrolases - metabolism | Muscle, Smooth - cytology | Epoxide Hydrolases - antagonists & inhibitors | Receptors, Prostaglandin E - metabolism | Urea - pharmacology | Physiological aspects | Thromboxanes | Genetic aspects | Bronchi | Measurement | Studies | Tissue | Airway management | Medical treatment | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 01/2009, Volume 104, Issue 2, pp. 228 - 235
Hypertension and vascular dysfunction result in the increased release of endothelium-derived contracting factors (EDCFs), whose identity is poorly defined. We... 
Aging | Aorta | Cyclooxygenase-2 | Thromboxane-prostanoid receptor | Endothelium-derived contracting factors
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 01/2006, Volume 290, Issue 1, pp. 295 - 303
Journal Article
JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, ISSN 0867-5910, 04/2014, Volume 65, Issue 2, pp. 283 - 293
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 09/2013, Volume 305, Issue 6, pp. F830 - F838
The present renal hemodynamic study tested the hypothesis that CD38 and superoxide anion (O2(center dot-)) participate in the vasoconstriction produced by... 
Oxidative stress | Thromboxane prostanoid receptor | Afferent arteriole | U-46619 | Tempol | Superoxide dismutase | Kidney | Renal vascular resistance | Renal circulation | renal circulation | PROTEIN-KINASE-C | PHYSIOLOGY | tempol | TUBULOGLOMERULAR FEEDBACK | ANGIOTENSIN-II | MICE LACKING | renal vascular resistance | O-2(center dot-) production | kidney | INDUCED HYPERTENSION | thromboxane prostanoid receptor | superoxide dismutase | RYANODINE RECEPTORS | ARTERIAL SMOOTH-MUSCLE | AFFERENT ARTERIOLES | NITRIC-OXIDE | UROLOGY & NEPHROLOGY | afferent arteriole | oxidative stress | ADP-ribosyl Cyclase 1 - deficiency | Kidney - blood supply | Mice, Inbred C57BL | Superoxides - pharmacology | ADP-ribosyl Cyclase 1 - physiology | Spin Labels | Arterioles - drug effects | Vasoconstriction - drug effects | Kidney - metabolism | Membrane Glycoproteins - physiology | Animals | Receptors, Thromboxane - drug effects | Cyclic N-Oxides - pharmacology | 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid - pharmacology | Mice | Receptors, Thromboxane - physiology | Membrane Glycoproteins - deficiency | Thromboxanes | Vasoconstriction | Causes of | Dosage and administration | Kidney diseases | Research | Observations | Properties | Antioxidants | T cell receptors | Kidneys | Rodents | Cells | Index Medicus | O2·− production
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 03/2007, Volume 150, Issue 5, pp. 624 - 632
Background and purpose: To study the importance of endothelium-derived contracting factors (EDCFs) in arteries of rats with type 1 diabetes. Experimental... 
endothelium | streptozotocin‐induced diabetes | endothelium‐derived contracting factor(s) | smooth muscle | thromboxane‐prostanoid receptor | cyclooxygenase | endothelium‐dependent contractions | Endothelium-derived contracting factor(s) | Cyclooxygenase | Thromboxane-prostanoid receptor | Endothelium-dependent contractions | Smooth muscle | Endothelium | Streptozotocin-induced diabetes | PROSTAGLANDIN H-2 | RECEPTOR ANTAGONISTS | SPONTANEOUSLY HYPERTENSIVE-RAT | ACETYLCHOLINE | PROSTACYCLIN | RABBIT AORTA | PHARMACOLOGICAL ANALYSIS | thromboxane-prostanoid receptor | SMOOTH-MUSCLE | streptozotocin-induced diabetes | endothelium-derived contracting factor(s) | NITRIC-OXIDE | SHR AORTA | PHARMACOLOGY & PHARMACY | endothelium-dependent contractions | Calcium - metabolism | Endothelium, Vascular - drug effects | Endothelins - metabolism | Muscle, Smooth, Vascular - physiopathology | Cyclooxygenase 2 - biosynthesis | Dose-Response Relationship, Drug | Time Factors | Diabetes Mellitus, Experimental - metabolism | Ionophores - pharmacology | Diabetes Mellitus, Experimental - physiopathology | Muscle, Smooth, Vascular - drug effects | Cyclooxygenase 1 - biosynthesis | Femoral Artery - physiopathology | Endothelium, Vascular - physiopathology | Rats | Femoral Artery - drug effects | Calcimycin - pharmacology | Vasoconstriction - drug effects | Blotting, Western | Cyclooxygenase Inhibitors - pharmacology | Thromboxane A2 - metabolism | Membrane Proteins - biosynthesis | Animals | Endothelium, Vascular - metabolism | Receptors, Thromboxane - metabolism | Vasodilation - drug effects | Receptors, Prostaglandin E - metabolism | Index Medicus | Research Papers
Journal Article