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The Journal of biological chemistry, ISSN 0021-9258, 11/2013, Volume 288, Issue 47, pp. 34030 - 34040
Many agonists, acting through G-protein-coupled receptors and G subunits of the heterotrimeric G-proteins, induce contraction of smooth muscle through an... 
Rho | Calcium | Signal Transduction | Smooth Muscle | Guanine Nucleotide Exchange Factor (GEF) | HETEROTRIMERIC G-PROTEINS | CRYSTAL-STRUCTURE | FLASH-PHOTOLYSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANGIOTENSIN-II | SIGNAL-TRANSDUCTION | ADENOSINE-TRIPHOSPHATE | LEUKEMIA-ASSOCIATED RHO | PDZ-RHOGEF | MYOSIN PHOSPHATASE | LIVING CELLS | Guanosine 5'-O-(3-Thiotriphosphate) - pharmacology | Phenylephrine - analogs & derivatives | Gene Silencing - drug effects | Calcium - metabolism | Humans | rhoA GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - genetics | rho-Specific Guanine Nucleotide Dissociation Inhibitors - genetics | Phenylephrine - pharmacology | rho-Specific Guanine Nucleotide Dissociation Inhibitors - metabolism | Guanine Nucleotide Exchange Factors - metabolism | Rho Guanine Nucleotide Exchange Factors - metabolism | Organ Culture Techniques | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Cell Line | Rabbits | Guanine Nucleotide Exchange Factors - genetics | Receptors, Thromboxane A2, Prostaglandin H2 - metabolism | rho GTP-Binding Proteins - genetics | Rats | Recombinant Proteins - genetics | Rho Guanine Nucleotide Exchange Factors - agonists | Rho Guanine Nucleotide Exchange Factors - genetics | Recombinant Proteins - pharmacology | Receptor, Endothelin A - genetics | Receptors, Thromboxane A2, Prostaglandin H2 - genetics | Guanine Nucleotide Exchange Factors - agonists | Guanosine 5'-O-(3-Thiotriphosphate) - analogs & derivatives | Mice, Knockout | Animals | rho GTP-Binding Proteins - metabolism | Receptor, Endothelin A - metabolism | Mice | Protein Multimerization - drug effects | Molecular Biophysics
Journal Article
Progress in Lipid Research, ISSN 0163-7827, 01/2016, Volume 61, pp. 149 - 162
The nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ) is the key decisive factor controlling the development of adipocytes. Ligand-mediated... 
Lipoxygenases | Cyclooxygenases | Reactive oxygen species | Polyunsaturated fatty acids | PPARγ | Adipogenesis | AF-1 ligand-independent activation function | NOS nitric oxide synthase | ADH alcohol dehydrogenase | ELOVL3 elongation of very long chain fatty acids 3 | FFA free fatty acid | DPEP dipeptidase | LNO | RXR retinoic X receptor | PTM post-translational modification | prostaglandin J | NOX4 NADPH oxidase 4 | azPC azelayol phosphatidylcholine | HPETE hydroperoxyeicosatetraenoic acid | GGT gamma-glutamyltransferase | MEF mouse embryonic fibroblast | C/EBP CCAAT/enhancer binding protein | TZD thiazolidinedione | Mo-Co molybdenum cofactor | CBR carbonyl reductase | HPODE hydroperoxyoctadecadienoic acid | AA arachidonic acid | HETE hydroxyeicosatrienoic acid | MAPK mitogen-activated protein kinase | PL phospholipase | pRB retinoblastoma protein | Abbreviations NO nitric oxide | cPLA | PTGR prostaglandin reductase | EET epoxyeicosatrienoic | PPARγ peroxisome proliferator-activated receptor γ | ROS reactive oxygen species | cytosolic PLA | EH epoxide hydrolase | BAT Brown adipose tissue | HODE hydroxyoctdecenonic acid | PTGES prostaglandin E synthase | LOX lipoxygenase | Epac exchange protein directly activated by cAMP | LPA lysophosphatidic acid | ChREBP carbohydrate element binding protein | NR nuclear receptor | LA linoleic acid | XOR xanthine oxidoreductase | CPA cyclic phosphatidic acid | AF-2 ligand-dependent activation function | TX thromboxane | 15-deoxy-Δ | PGDH 15-hydroxyprostaglandin dehydrogenase | PGFS prostaglandin F synthase | KETE ketoeicosatetraenoic acid | SREBP-1c sterol-regulatory element binding protein 1c | eLOX3 epidermis lipoxygenase type 3 | GPC glycerophosphocholine | LBD ligand binding domain | nitrolinoleic acid | PTGIS prostacyclin synthase | ONO | PG prostaglandin | RetSat retinol saturase | dioxide radical | EPA eicosapentaenoic acid | MUFA monounsaturated fatty acid | GPx glutathione peroxidase | LTC4S leukotriene C4 synthase | COX cyclooxygenase | IBMX isobutyl-methylxanthine | peroxynitrite | PPRE peroxisome proliferator response element | HPGD 15-hydroxyprostaglandin dehydrogenase | 15-dPGJ | DHET dihydroxyeicosatrienoic acid | FAS fatty acid synthase | PTGDS prostaglandin D2 synthase | sEH soluble epoxide hydrolase | UCP1 uncoupling protein 1 | CYP cytochrome P450 monooxygenase | WAT white adipose tissue | superoxide | FAD flavin adenine dinucleotide | PUFA polyunsaturated fatty acid | TBXAS thromboxane A synthase | INHIBITS ADIPOCYTE DIFFERENTIATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOMINANT-NEGATIVE MUTATIONS | FATTY-ACIDS | PREADIPOCYTE DIFFERENTIATION | PPAR gamma | WHITE ADIPOSE-TISSUE | NUTRITION & DIETETICS | INSULIN-RESISTANCE | ACTIVATED-RECEPTOR-GAMMA | NITRIC-OXIDE | GENE-EXPRESSION | LIGAND-BINDING DOMAIN | PPAR gamma - physiology | Prostaglandins | Animals | Oxidation-Reduction | Humans | Lipid Metabolism | Adipocytes - physiology | Fatty Acids - metabolism
Journal Article
Journal Article
Blood, ISSN 0006-4971, 12/2012, Volume 120, Issue 25, pp. 5041 - 5049
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 03/2007, Volume 5, Issue 3, pp. 551 - 559
Background: We report a novel case of gray platelet syndrome (GPS). A 14‐year‐old boy had bleeding diathesis, mild thrombocytopenia, giant platelets with... 
gray platelet syndrome | thromboxane biosynthesis | thrombin receptors | platelet protease‐activated receptors | platelet α‐granules | Thrombin receptors | Plateletα-granules | Platelet protease-activated receptors | Thromboxane biosynthesis | Gray platelet syndrome | STORAGE POOL DEFICIENCY | LOCALIZATION | MECHANISM | TRAFFICKING | platelet alpha-granules | THROMBOXANE PRODUCTION | MEGAKARYOCYTES | PERIPHERAL VASCULAR DISEASE | platelet protease-activated receptors | HEMATOLOGY | Platelet Storage Pool Deficiency - pathology | Receptor, PAR-1 - metabolism | Humans | Middle Aged | Male | Platelet Storage Pool Deficiency - metabolism | Thrombin - pharmacology | Coagulants - pharmacology | Platelet Function Tests | Adult | Female | Platelet Aggregation - drug effects | P-Selectin - analysis | Blood Platelets - drug effects | Receptor, PAR-1 - agonists | Platelet Factor 4 - analysis | Platelet Storage Pool Deficiency - blood | Receptor, PAR-1 - genetics | Syndrome | Thrombospondin 1 - analysis | Phenotype | Cytoplasmic Granules - ultrastructure | Blood Platelets - metabolism | Calcium Signaling - drug effects | Pedigree | Blood Platelets - ultrastructure | Adolescent | Family | Aged | Thromboxane B2 - blood | Oligopeptides - pharmacology | Microscopy, Fluorescence | Platelet Storage Pool Deficiency - diagnosis | Platelet Storage Pool Deficiency - genetics
Journal Article
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 05/2017, Volume 803, pp. 39 - 47