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DNA Repair, ISSN 1568-7864, 07/2016, Volume 43, pp. 78 - 88
The family of Ten-Eleven Translocation (TET) proteins is implicated in the process of active DNA demethylation and thus in epigenetic regulation. TET 1, 2 and... 
TET2 | Genetic instability | 5-hmC | TDG | Cell cycle | 5-METHYLCYTOSINE | CONVERSION | ACUTE MYELOID-LEUKEMIA | TET PROTEINS | MLL | THYMINE DNA GLYCOSYLASE | DEMETHYLATION | GENETICS & HEREDITY | TOXICOLOGY | 5-FORMYLCYTOSINE | 5-CARBOXYLCYTOSINE | Cytosine - analogs & derivatives | Genomic Instability | 5-Methylcytosine - analogs & derivatives | Epigenesis, Genetic | Humans | Tumor Suppressor Protein p53 - genetics | DNA-Binding Proteins - metabolism | Cytosine - metabolism | Base Sequence | S Phase | Thymine DNA Glycosylase - genetics | B-Lymphocytes - metabolism | Megakaryocyte Progenitor Cells - cytology | Fibroblasts - metabolism | Proto-Oncogene Proteins - metabolism | Cell Line | B-Lymphocytes - cytology | Hydroxylation | Tumor Suppressor Protein p53 - metabolism | Proto-Oncogene Proteins - genetics | DNA-Binding Proteins - genetics | Megakaryocyte Progenitor Cells - metabolism | Animals | 5-Methylcytosine - metabolism | Mutagenesis | DNA Repair | Thymine DNA Glycosylase - deficiency | Fibroblasts - cytology | Mice | Index Medicus | Megakaryocyte Progenitor Cells/metabolism | Thymine DNA Glycosylase/genetics | Proto-Oncogene Proteins/genetics | Cytosine/metabolism | B-Lymphocytes/metabolism | Genomics | Cytosine/analogs & derivatives | Tumor Suppressor Protein p53/metabolism | DNA-Binding Proteins/metabolism | B-Lymphocytes/cytology | Life Sciences | Thymine DNA Glycosylase/deficiency | Fibroblasts/metabolism | Fibroblasts/cytology | Biochemistry, Molecular Biology | 5-Methylcytosine/metabolism | Proto-Oncogene Proteins/metabolism | Tumor Suppressor Protein p53/genetics | Megakaryocyte Progenitor Cells/cytology | 5-Methylcytosine/analogs & derivatives | DNA-Binding Proteins/genetics
Journal Article
Nature, ISSN 0028-0836, 02/2018, Volume 554, Issue 7690, pp. 128 - 132
Folates enable the activation and transfer of one-carbon units for the biosynthesis of purines, thymidine and methionine(1-3). Antifolates are important... 
CHAIN | HYPERTROPHIC CARDIOMYOPATHY | SERINE HYDROXYMETHYLTRANSFERASE | METABOLISM | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | DEFECT | LACTIC-ACIDOSIS | MUTATIONS | IDENTIFICATION | ANTICODON WOBBLE NUCLEOTIDE | Mitochondria - enzymology | Electron Transport | Protein Biosynthesis | Humans | Ribosomes - metabolism | Sarcosine - metabolism | Multifunctional Enzymes - metabolism | Thymine Nucleotides - biosynthesis | Oxidative Phosphorylation - drug effects | Glycine Hydroxymethyltransferase - deficiency | HEK293 Cells | RNA, Transfer - genetics | Codon - genetics | RNA, Transfer - chemistry | Leucine - genetics | Methylenetetrahydrofolate Dehydrogenase (NADP) - metabolism | Biocatalysis | RNA, Transfer - metabolism | HCT116 Cells | Mitochondria - metabolism | Mitochondria - drug effects | Glycine Hydroxymethyltransferase - metabolism | Guanosine - metabolism | Tetrahydrofolates - metabolism | Lysine - genetics | Carrier Proteins - metabolism | Methylation - drug effects | Folic Acid - metabolism | Aminohydrolases - metabolism | Folic Acid Antagonists - pharmacology | GTP-Binding Proteins - metabolism | Mitochondria | Physiological aspects | Genetic aspects | Methylation | Observations | Genetic translation | Folic acid | Transfer RNA | Phosphorylation | Inborn errors of metabolism | Peptides | Serine | Biosynthesis | Mitochondrial DNA | Thymidine | Catalytic activity | Leucine | Cytosol | Experiments | Anticancer properties | Proteins | Purines | Antitumor agents | Metabolites | Lymphocytes | Vitamin B | Catalysis | Enzymes | Translation | tRNA Ala | tRNA | Methionine | Metabolism | Carbon | Immunosuppression | Oxidative phosphorylation | Lysine | Proteomics | Electron transport | Respiration | Codons | Cancer
Journal Article
Science, ISSN 0036-8075, 11/2007, Volume 318, Issue 5855, pp. 1469 - 1472
Journal Article
Endocrinology, ISSN 0013-7227, 11/2015, Volume 156, Issue 11, pp. 4105 - 4114
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2016, Volume 113, Issue 8, pp. 2176 - 2181
Journal Article
Journal Article
Epigenetics, ISSN 1559-2294, 03/2013, Volume 8, Issue 3, pp. 317 - 332
Myogenic cell cultures derived from muscle biopsies are excellent models for human cell differentiation. We report the first comprehensive analysis of... 
myoblasts | DNaseI hypersensitivity | enhancers | alternative splicing | facioscapulohumeral muscular dystrophy | 5-hydroxymethylcytosine | muscle | DNA methylation | TET1 | histone H3 methylation | Facioscapulohumeral muscular dystrophy | Alternative splicing | Enhancers | Histone H3 methylation | Muscle | DNasei hypersensitivity | Myoblasts | TBX1 | STEM-CELLS | OPEN CHROMATIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | PAX3 | MYOGENIC DIFFERENTIATION | RNA-SEQ | GENE-EXPRESSION | THYMINE DNA | NEURAL CREST | Paired Box Transcription Factors - genetics | Cytosine - analogs & derivatives | 5-Methylcytosine - analogs & derivatives | Epigenesis, Genetic | Humans | Middle Aged | Myosin Heavy Chains - genetics | Male | Muscular Dystrophy, Facioscapulohumeral - genetics | Muscle Fibers, Skeletal - metabolism | Myosin Heavy Chains - metabolism | Case-Control Studies | DNA-Binding Proteins - metabolism | Mixed Function Oxygenases | DNA Methylation | Myoblasts - metabolism | Cytosine - metabolism | Gene Expression Regulation, Developmental | Guanine Nucleotide Exchange Factors - metabolism | Muscle Proteins - metabolism | Aged, 80 and over | Adult | Female | Transcription, Genetic | Child | Muscular Dystrophy, Facioscapulohumeral - metabolism | Cardiac Myosins - metabolism | Cell Lineage - genetics | Genes, Homeobox | Infant, Newborn | Repressor Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Guanine Nucleotide Exchange Factors - genetics | PAX3 Transcription Factor | Cardiac Myosins - genetics | Proto-Oncogene Proteins - genetics | Rho Guanine Nucleotide Exchange Factors | DNA-Binding Proteins - genetics | T-Box Domain Proteins - genetics | T-Box Domain Proteins - metabolism | Muscle Proteins - genetics | CCCTC-Binding Factor | Adolescent | Muscle Development - genetics | Aged | Histones - metabolism | Genome, Human | Paired Box Transcription Factors - metabolism | Research Paper
Journal Article
Nature, ISSN 0028-0836, 12/2011, Volume 480, Issue 7377, pp. 379 - 382
Journal Article
Physiology & Behavior, ISSN 0031-9384, 09/2017, Volume 178, pp. 82 - 92
Aberrant glucocorticoid secretion is implicated in the pathophysiology of stress-related disorders (i.e., depression, anxiety). Glucocorticoids exert... 
c-Fos | Restraint | Depression-like behavior | Forced swim test | Antidepressants | HPA-axis | CORTICOTROPIN-RELEASING HORMONE | ANXIETY-LIKE BEHAVIOR | ANTAGONIST SPIRONOLACTONE | GLUCOCORTICOID-RECEPTOR | MEDIAL PREFRONTAL CORTEX | GENE-EXPRESSION | BEHAVIORAL SCIENCES | PSYCHOLOGY, BIOLOGICAL | PITUITARY-ADRENAL AXIS | C-FOS EXPRESSION | Motor Activity - physiology | Neurons - pathology | Amygdala - drug effects | Depression - pathology | Receptors, Mineralocorticoid - metabolism | Thymine - analogs & derivatives | Motor Activity - drug effects | Male | Receptors, Glucocorticoid - metabolism | Hippocampus - drug effects | Prefrontal Cortex - pathology | Depression - drug therapy | Depression - metabolism | Prefrontal Cortex - drug effects | Psychotropic Drugs - pharmacology | Stress, Psychological - metabolism | Neurons - metabolism | Thymine - pharmacology | Neurons - drug effects | Hormones - pharmacology | Stress, Psychological - drug therapy | Amygdala - metabolism | Proto-Oncogene Proteins c-fos - metabolism | Hippocampus - pathology | Random Allocation | Rats, Sprague-Dawley | Amygdala - pathology | Stress, Psychological - pathology | Hippocampus - metabolism | Paraventricular Hypothalamic Nucleus - drug effects | Animals | Paraventricular Hypothalamic Nucleus - metabolism | Prefrontal Cortex - metabolism | Corticosterone - metabolism | Imipramine - pharmacology | Paraventricular Hypothalamic Nucleus - pathology | Corticosteroids | Depression, Mental | Psychophysiology
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 2014, Volume 10, Issue 7, pp. 574 - 581
Journal Article