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Human Pathology, ISSN 0046-8177, 2013, Volume 44, Issue 11, pp. 2563 - 2570
Summary BRAF mutation is seen in a variety of human neoplasms including cutaneous malignant melanoma, papillary thyroid carcinoma, colorectal carcinoma,... 
Pathology | Immunohistochemistry | Anti–B-Raf | BRAF V600E | VE1 | Glioma | Melanoma | Thyroid carcinoma | Anti-B-Raf | PROTEIN | IMPROVED SURVIVAL | PATHOLOGY | CANCER | TUMORS | HAIRY-CELL LEUKEMIA | THERAPY | MEK INHIBITION | GENE | MUTANT BRAF | VEMURAFENIB | Neoplasms - metabolism | Gastrointestinal Neoplasms - genetics | Humans | Lung Neoplasms - metabolism | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Mutation, Missense | Breast Neoplasms - metabolism | Glioma - metabolism | Glioma - genetics | Ovarian Neoplasms - genetics | Gastrointestinal Neoplasms - pathology | Neoplasms - genetics | DNA Mutational Analysis | Melanoma - genetics | Glioma - pathology | Sensitivity and Specificity | Biomarkers, Tumor - metabolism | Female | Ovarian Neoplasms - metabolism | Carcinoma - pathology | Antibodies, Monoclonal - immunology | Proto-Oncogene Proteins B-raf - metabolism | Gastrointestinal Neoplasms - metabolism | Lung Neoplasms - genetics | Melanoma - metabolism | Mutant Proteins - genetics | Mutant Proteins - metabolism | Melanoma - pathology | Thyroid Neoplasms - genetics | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Proto-Oncogene Proteins B-raf - genetics | Carcinoma - genetics | Biomarkers, Tumor - genetics | Carcinoma - metabolism | Neoplasms - pathology | Amino Acid Substitution | Thyroid Neoplasms - metabolism | Thyroid Neoplasms - pathology | Carcinoma | Gene mutations | Gliomas | Thyroid diseases | Monoclonal antibodies | Genetic aspects | Comparative analysis | Lung cancer, Non-small cell | Cancer | Breast cancer | Mutation | Tumors | Skin cancer | Index Medicus
Journal Article
Cancer, ISSN 0008-543X, 12/2014, Volume 120, Issue 23, pp. 3627 - 3634
Journal Article
Scientific Reports, ISSN 2045-2322, 08/2014, Volume 4, Issue 1, pp. 6088 - 6088
Some long noncoding RNAs (lncRNAs) play important roles in the regulation of gene expression by acting as competing endogenous RNAs (ceRNAs). However, the... 
MESSENGER-RNAS | DATABASE | GENE | ANNOTATION | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MICRORNA TARGETS | CERNA HYPOTHESIS | NETWORKS | IDENTIFICATION | EXPRESSION | Oligonucleotide Array Sequence Analysis | Carcinoma, Squamous Cell - genetics | Humans | Male | Gene Expression Profiling | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Ovarian Neoplasms - genetics | Retinoblastoma Protein - biosynthesis | Squamous Cell Carcinoma of Head and Neck | Prostatic Neoplasms - genetics | RNA Interference | Cell Transformation, Neoplastic - genetics | Female | Gene Expression Regulation, Neoplastic - genetics | Stomach Neoplasms - genetics | Pituitary Neoplasms - genetics | RNA, Long Noncoding - genetics | Thyroid Cancer, Papillary | Thyroid Neoplasms - genetics | Algorithms | Carcinoma, Papillary | Retinoblastoma Protein - genetics | Cell Line, Tumor | Carcinoma - genetics | Head and Neck Neoplasms - genetics | MicroRNAs - genetics | RNA, Small Interfering | Post-transcription | Transcription | Gene regulation | Regulatory sequences | Stomach cancer | Ovarian cancer | Neck | Gastric cancer | Thyroid | Squamous cell carcinoma | Chronic lymphatic leukemia | MiRNA | Pituitary (anterior) | Runx1 protein | siRNA | Lymphatic leukemia | Gene expression | DNA microarrays | Pituitary | Interleukin 10 | Head and neck cancer | Prostate | Prostate cancer | PTEN protein | Papillary thyroid carcinoma | Tumors | Index Medicus
Journal Article
Genes and Development, ISSN 0890-9369, 06/2006, Volume 20, Issue 12, pp. 1569 - 1574
The tumor suppressor PTEN is frequently inactivated in human cancers. A major downstream effector of PTEN is Akt, which is hyperactivated via PTEN... 
Intestinal polyps | PIN | Endometrium carcinoma | Thyroid and adrenal tumors | Cancer therapy | AKT/PKB | GENETICALLY-ENGINEERED MICE | PTEN | DEVELOPMENTAL BIOLOGY | PHOSPHOINOSITIDE 3-KINASE | CANCER | CELL BIOLOGY | cancer therapy | PATHWAY | thyroid and adrenal tumors | NEOPLASIA | RELEVANCE | intestinal polyps | MUTATION | GENETICS & HEREDITY | endometrium carcinoma | Prostatic Intraepithelial Neoplasia - pathology | Thyroid Neoplasms - enzymology | Proto-Oncogene Proteins c-akt - deficiency | Male | Intestinal Polyps - enzymology | Proto-Oncogene Proteins c-akt - genetics | Adrenal Gland Neoplasms - enzymology | Prostatic Neoplasms - genetics | Endometrial Neoplasms - genetics | Neoplasms - genetics | Female | Pseudolymphoma - genetics | Pseudolymphoma - enzymology | Adrenal Gland Neoplasms - pathology | PTEN Phosphohydrolase - genetics | Prostatic Neoplasms - pathology | Endometrial Neoplasms - enzymology | Neoplasms - enzymology | PTEN Phosphohydrolase - metabolism | Pseudolymphoma - pathology | Thyroid Neoplasms - genetics | Animals | Prostatic Intraepithelial Neoplasia - enzymology | Intestinal Polyps - pathology | Prostatic Neoplasms - enzymology | Endometrial Neoplasms - pathology | Heterozygote | Mice | Prostatic Intraepithelial Neoplasia - genetics | Neoplasms - pathology | Adrenal Gland Neoplasms - genetics | Thyroid Neoplasms - pathology | Index Medicus | Research Communication
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2016, Volume 126, Issue 3, pp. 1052 - 1066
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, pp. e79584 - e79584
MicroRNAs (miRNAs) are small non-coding RNA molecules, which participate in diverse biological processes and may regulate tumor suppressor genes or oncogenes.... 
BREAST-CANCER | TURKISH POPULATION | HEPATOCELLULAR-CARCINOMA | FUNCTIONAL POLYMORPHISM | GASTRIC-CANCER | COLORECTAL-CANCER | MULTIDISCIPLINARY SCIENCES | PRE-MICRORNAS | SQUAMOUS-CELL CARCINOMA | COMMON GENETIC-VARIANTS | THAN-C POLYMORPHISM | Stomach Neoplasms - genetics | Genetic Predisposition to Disease - genetics | Carcinoma, Squamous Cell - genetics | Humans | Genotype | Male | Case-Control Studies | Thyroid Cancer, Papillary | Thyroid Neoplasms - genetics | Squamous Cell Carcinoma of Head and Neck | Breast Neoplasms - genetics | Prostatic Neoplasms - genetics | Urinary Bladder Neoplasms - genetics | Carcinoma, Papillary | Polymorphism, Single Nucleotide - genetics | Carcinoma - genetics | Female | Head and Neck Neoplasms - genetics | MicroRNAs - genetics | Squamous cell carcinoma | Oncology, Experimental | Colorectal cancer | Development and progression | Research | Risk factors | MicroRNA | Genetic aspects | Single nucleotide polymorphisms | Health aspects | Chromosomes | Prostate cancer | Cancer | Motility | Laboratories | Colorectal carcinoma | Genes | Lung cancer | Bladder | Systematic review | Single-nucleotide polymorphism | Epidemiology | Thyroid carcinoma | Confidence intervals | Liver cancer | Urinary bladder | Life sciences | Neck | Gastric cancer | Thyroid | Head | Statistical analysis | Health risks | MiRNA | Breast cancer | Risk analysis | Ribonucleic acid--RNA | Biological activity | Meta-analysis | Studies | Ethnicity | MicroRNAs | Tumor suppressor genes | Genetic engineering | Non-coding RNA | Prostate | Binding sites | Cervical cancer | Papillary thyroid carcinoma | Polymorphism | Index Medicus | RNA | Ribonucleic acid
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2015, Volume 373, Issue 8, pp. 726 - 736
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 2011, Volume 121, Issue 3, pp. 397 - 405
Missense mutations of the V600E type constitute the vast majority of tumor-associated somatic alterations in the v-RAF murine sarcoma viral oncogene homolog B1... 
Brain tumor | Pathology | Neurosciences | Ganglioglioma | V600E mutation | Medicine & Public Health | BRAF | Pleomorphic xanthoastrocytoma | GLIOMAS | B-RAF GENE | PATHOLOGY | CANCER | NEUROSCIENCES | CLINICAL NEUROLOGY | PATHWAY ACTIVATION | ATYPICAL TERATOID/RHABDOID TUMOR | COMPONENT | DUPLICATION | INHIBITOR | MAPK PATHWAY | EXPRESSION | Astrocytoma - genetics | Gene Frequency - genetics | World Health Organization | Signal Transduction | Humans | Brain Neoplasms - pathology | Brain Neoplasms - genetics | Child, Preschool | Exons - genetics | Mutation, Missense - genetics | Young Adult | Ganglioglioma - genetics | Astrocytoma - pathology | Proto-Oncogene Proteins B-raf - genetics | Ganglioglioma - pathology | Adolescent | Adult | Nervous System Neoplasms - genetics | Retrospective Studies | Child | Nervous System Neoplasms - pathology | Medical colleges | Molecular genetics | Sarcoma | Neurons | Brain tumors | Oncology, Experimental | Melanoma | Thyroid diseases | Research | Codon | Gene mutations | Gliomas | Analysis | Genetic research | Genetic aspects | Cancer | Index Medicus | meningioma | Pediatrics | Exons | Glioblastoma | Clinical trials | Insertion | Adenoma | Neuronal-glial interactions | Missense mutation | Sheaths | Colon | Astrocytoma | Oncogenes | Peripheral nervous system | Astrocytes | Base pairs | Central nervous system diseases | Glioma | Pituitary | Codons | papillary thyroid carcinoma | Tumors
Journal Article
Clinical Epigenetics, ISSN 1868-7075, 01/2016, Volume 8, Issue 1, pp. 1 - 16
Journal Article