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Human Pathology, ISSN 0046-8177, 2013, Volume 44, Issue 11, pp. 2563 - 2570
Summary BRAF mutation is seen in a variety of human neoplasms including cutaneous malignant melanoma, papillary thyroid carcinoma, colorectal carcinoma,... 
Pathology | Immunohistochemistry | Anti–B-Raf | BRAF V600E | VE1 | Glioma | Melanoma | Thyroid carcinoma | Anti-B-Raf | PROTEIN | IMPROVED SURVIVAL | PATHOLOGY | CANCER | TUMORS | HAIRY-CELL LEUKEMIA | THERAPY | MEK INHIBITION | GENE | MUTANT BRAF | VEMURAFENIB | Neoplasms - metabolism | Gastrointestinal Neoplasms - genetics | Humans | Lung Neoplasms - metabolism | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Mutation, Missense | Breast Neoplasms - metabolism | Glioma - metabolism | Glioma - genetics | Ovarian Neoplasms - genetics | Gastrointestinal Neoplasms - pathology | Neoplasms - genetics | DNA Mutational Analysis | Melanoma - genetics | Glioma - pathology | Sensitivity and Specificity | Biomarkers, Tumor - metabolism | Female | Ovarian Neoplasms - metabolism | Carcinoma - pathology | Antibodies, Monoclonal - immunology | Proto-Oncogene Proteins B-raf - metabolism | Gastrointestinal Neoplasms - metabolism | Lung Neoplasms - genetics | Melanoma - metabolism | Mutant Proteins - genetics | Mutant Proteins - metabolism | Melanoma - pathology | Thyroid Neoplasms - genetics | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Proto-Oncogene Proteins B-raf - genetics | Carcinoma - genetics | Biomarkers, Tumor - genetics | Carcinoma - metabolism | Neoplasms - pathology | Amino Acid Substitution | Thyroid Neoplasms - metabolism | Thyroid Neoplasms - pathology | Carcinoma | Gene mutations | Gliomas | Thyroid diseases | Monoclonal antibodies | Genetic aspects | Comparative analysis | Lung cancer, Non-small cell | Cancer | Breast cancer | Mutation | Tumors | Skin cancer | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, pp. e60317 - e60317
Aberrant expression of microRNA-146a (miR-146a) has been reported to be involved in the development and progression of various types of cancers. However, its... 
SUPPRESSOR | ONCOGENESIS | RNA | MULTIDISCIPLINARY SCIENCES | CERVICAL-CANCER | INTERFERENCE | MICRORNAS | NF-KAPPA-B | FACTOR RECEPTOR | EXPRESSION | CONTRIBUTES | Lung Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Middle Aged | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Male | MicroRNAs - metabolism | NF-kappa B - metabolism | Receptor, Epidermal Growth Factor - metabolism | Antibodies, Monoclonal, Humanized - pharmacology | Aged, 80 and over | Adult | Female | Antineoplastic Agents - pharmacology | Lung - metabolism | Cetuximab | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Lung - pathology | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Lung - drug effects | Cell Line, Tumor | Aged | Cell Proliferation - drug effects | MicroRNAs - genetics | Carcinoma, Non-Small-Cell Lung - drug therapy | Apoptosis | Cell Movement | MicroRNA | Growth | Monoclonal antibodies | Lung cancer, Small cell | Development and progression | Lung cancer, Non-small cell | Health aspects | Cell proliferation | Laboratories | Lung | Lung cancer | Oncology | Drug delivery | Kinases | Paraffin | Cancer therapies | Metastases | Signal transduction | Cell growth | Bioindicators | Inhibition | Gefitinib | Sensitizing | NF-κB protein | Phenotypes | Cytokines | Epidermal growth factor receptors | MiRNA | Non-small cell lung carcinoma | siRNA | Breast cancer | Gene expression | Ribonucleic acid--RNA | Patients | Pathology | Signaling | Chemotherapy | Thyroid cancer | MicroRNAs | Medical prognosis | Pancreatic cancer | Cell lines | Biomarkers | Mutation | Cell migration | Cervical cancer | Tumors | Cancer | Index Medicus | Ribonucleic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, pp. e86872 - e86872
In contrast to normal differentiated cells that depend on mitochondrial oxidative phosphorylation for energy production, cancer cells have evolved to utilize... 
LIVER-CANCER | REGULATOR | NETWORK | PKM2 | MULTIDISCIPLINARY SCIENCES | ISOFORM | TUMOR-GROWTH | MICRORNA-122 | RNA, Small Interfering - genetics | Carcinoma, Hepatocellular - mortality | Cell Proliferation | Prognosis | Oligonucleotide Array Sequence Analysis | Humans | Middle Aged | Male | Gene Expression Profiling | Liver Neoplasms - mortality | Neoplasm Recurrence, Local - mortality | Immunoenzyme Techniques | Neoplasm Recurrence, Local - pathology | Carcinoma, Hepatocellular - genetics | Biomarkers, Tumor - metabolism | Female | Liver Neoplasms - pathology | Membrane Proteins - metabolism | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Liver Neoplasms - genetics | Neoplasm Recurrence, Local - metabolism | Membrane Proteins - genetics | Lactic Acid - metabolism | RNA, Messenger - genetics | Carrier Proteins - antagonists & inhibitors | Oxygen Consumption | Survival Rate | Thyroid Hormones - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Carrier Proteins - genetics | Carrier Proteins - metabolism | Membrane Proteins - antagonists & inhibitors | Thyroid Hormones - metabolism | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Glycolysis | Neoplasm Recurrence, Local - genetics | Biomarkers, Tumor - genetics | MicroRNAs - genetics | Neoplasm Staging | Apoptosis | Carcinoma, Hepatocellular - metabolism | Lactates | Glucose metabolism | RNA | Analysis | Genes | Physiological aspects | Hepatoma | Gene expression | Health aspects | Cell proliferation | Phosphorylation | Liver | Correlation coefficients | Science | Pyruvic acid | Oncology | Hepatocellular carcinoma | Kinases | Tissues | Metastases | Liver cancer | Angiogenesis | Mitochondria | Rodents | Surgery | Correlation coefficient | Pyruvate kinase | MiRNA | Oxygen consumption | Pharmacology | Metabolism | Biological activity | Intermediates | Hospitals | Oxidative phosphorylation | Ribonucleic acids | MicroRNAs | Regulatory mechanisms (biology) | Stem cells | Metabolic pathways | Lactic acid | Cancer | Index Medicus
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 7/2011, Volume 122, Issue 1, pp. 11 - 19
Journal Article
American Journal of Surgical Pathology, ISSN 0147-5185, 2000, Volume 24, Issue 9, pp. 1217 - 1223
The distinction between small cell lung carcinoma (SCLC) and small cell carcinomas of other sites is difficult by routine histology. Thyroid transcription... 
Immunohistochemistry | Thyroid transcription factor-1 | Cytokeratin 20 | Small cell carcinoma | PULMONARY | SURGERY | cytokeratin 20 | PROTEIN | thyroid transcription factor-1 | ANTIBODY | FACTOR-I | PATHOLOGY | IDENTIFICATION | CYTOKERATIN-20 | THYROTROPIN RECEPTOR GENE | small cell carcinoma | immunohistochemistry | SKIN | PROMOTER | EXPRESSION | Prostatic Neoplasms - metabolism | Thyroid Neoplasms - diagnosis | Thyroid Nuclear Factor 1 | Pancreatic Neoplasms - metabolism | Pancreatic Neoplasms - diagnosis | Urinary Bladder Neoplasms - diagnosis | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Male | Uterine Cervical Neoplasms - pathology | Neuroendocrine Tumors - diagnosis | Prostatic Neoplasms - diagnosis | Carcinoma, Merkel Cell - diagnosis | Immunoenzyme Techniques | Paraffin Embedding | Gastrointestinal Neoplasms - pathology | Nuclear Proteins - biosynthesis | Uterine Cervical Neoplasms - metabolism | Salivary Gland Neoplasms - metabolism | Urinary Bladder Neoplasms - pathology | Female | Urinary Bladder Neoplasms - metabolism | Gastrointestinal Neoplasms - metabolism | Neuroendocrine Tumors - pathology | Prostatic Neoplasms - pathology | Diagnosis, Differential | Uterine Cervical Neoplasms - diagnosis | Carcinoma, Small Cell - metabolism | Neuroendocrine Tumors - metabolism | Pancreatic Neoplasms - pathology | Intermediate Filament Proteins - biosynthesis | Keratin-20 | Transcription Factors - biosynthesis | Gastrointestinal Neoplasms - diagnosis | Carcinoma, Small Cell - diagnosis | Salivary Gland Neoplasms - diagnosis | Carcinoma, Merkel Cell - metabolism | Carcinoma, Small Cell - pathology | Lung Neoplasms - diagnosis | Salivary Gland Neoplasms - pathology | Biomarkers, Tumor - biosynthesis | Carcinoma, Merkel Cell - pathology | Thyroid Neoplasms - metabolism | Thyroid Neoplasms - pathology | Index Medicus
Journal Article
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 2012, Volume 8, Issue 10, pp. 839 - 847
Cancer cells engage in a metabolic program to enhance biosynthesis and support cell proliferation. The regulatory properties of pyruvate kinase M2 (PKM2)... 
ISOZYME | INHIBITION | FRUCTOSE-1,6-BISPHOSPHATE | THYROID-HORMONE | CONVERSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ISOFORM | BINDING PROTEIN | CANCER-CELL METABOLISM | TUMOR-GROWTH | NUCLEAR TRANSLOCATION | Genes | Cells | Cancer | Tumors | Index Medicus | BASIC BIOLOGICAL SCIENCES
Journal Article