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1. Full Text Thyroid nodules: diagnosis and management
by Wong, Rosemary and Farrell, Stephen G and Grossmann, Mathis
Medical Journal of Australia, ISSN 0025-729X, 07/2018, Volume 209, Issue 2, pp. 92 - 98
Thyroid nodules are common. Their importance lies in the need to assess thyroid function, degree of and future risk of mass effect, and exclude thyroid cancer,... 
Endocrine system diseases | UNITED-STATES | MEDICINE, GENERAL & INTERNAL | FINE-NEEDLE-ASPIRATION | TASK-FORCE | ULTRASOUND | INDETERMINATE CYTOLOGY | CANCER INCIDENCE | RISK | ASSOCIATION GUIDELINES | PREOPERATIVE DIAGNOSIS | BETHESDA SYSTEM | Humans | Thyroid Nodule - therapy | Thyroid Nodule - diagnosis
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2. Full Text Machine Learning–Assisted System for Thyroid Nodule Diagnosis
by Zhang, Bin and Tian, Jie and Pei, Shufang and Chen, Yubing and He, Xin and Dong, Yuhao and Zhang, Lu and Mo, Xiaokai and Huang, Wenhui and Cong, Shuzhen and Zhang, Shuixing
Thyroid, ISSN 1050-7256, 06/2019, Volume 29, Issue 6, pp. 858 - 867
Background: Ultrasound (US) examination is helpful in the differential diagnosis of thyroid nodules (malignant vs. benign), but its accuracy relies heavily on... 
Thyroid Radiology and Nuclear Medicine | thyroid nodule | DIFFERENTIAL-DIAGNOSIS | MANAGEMENT | PERFORMANCE | SHEAR-WAVE ELASTOGRAPHY | diagnosis | ULTRASOUND ELASTOGRAPHY | random forest | machine learning | ultrasound | ACCURACY | REAL-TIME ELASTOGRAPHY | FINE-NEEDLE-ASPIRATION | BENIGN | ENDOCRINOLOGY & METABOLISM
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3. Full Text A pre-trained convolutional neural network based method for thyroid nodule diagnosis
by Ma, Jinlian and Wu, Fa and Zhu, Jiang and Xu, Dong and Kong, Dexing
Ultrasonics, ISSN 0041-624X, 01/2017, Volume 73, pp. 221 - 230
In ultrasound images, most thyroid nodules are in heterogeneous appearances with various internal components and also have vague boundaries, so it is difficult... 
Thyroid nodule | Feature extraction | Diagnosis | Ultrasound image | Convolutional neural network | Classification | LESION CLASSIFICATION | MODEL | COMBINATION | FEATURE-SELECTION | ACOUSTICS | TEXTURE | ULTRASOUND | BENIGN | IMAGES | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Neural networks | Analysis | Methods | Thyroid diseases
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4. Full Text Thyroid Nodules
: Diagnosis and Management
by Gharib, Hossein
2018, Contemporary Endocrinology, ISBN 9783319594736, 241
Utilizing the most current evidence, this practical book is the first publication of its kind to focus exclusively on the clinical and laboratory evaluation... 
Thyroid gland | Diseases | Medicine & Public Health | Endocrinology | Head and Neck Surgery
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5. Full Text Thyroid imaging reporting and data system combined with Bethesda classification in qualitative thyroid nodule diagnosis
by Tan, Huiwen and Li, Zhihui and Li, Nong and Qian, Jianrong and Fan, Fengchun and Zhong, Huiling and Feng, Jinquan and Xu, Huajun and Li, Zhongxing
Medicine, ISSN 0025-7974, 12/2019, Volume 98, Issue 50, p. e18320
We aimed to investigate the value of the combined use of high-resolution ultrasound thyroid imaging reporting and data system (TI-RADS) classification and... 
Biopsy, Fine-Needle - methods | Diagnosis, Differential | Follow-Up Studies | Thyroid Nodule - classification | Humans | Middle Aged | Thyroid Nodule - diagnosis | Tomography, X-Ray Computed - methods | Male | Thyroid Gland - diagnostic imaging | Young Adult | Adolescent | Adult | Female | ROC Curve | Aged | Retrospective Studies | Child | Ultrasonography - methods | Usage | Thyroid gland | Diagnosis | Biopsy | Thyroid diseases
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6. AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS, AMERICAN COLLEGE OF ENDOCRINOLOGY, AND ASSOCIAZIONE MEDICI ENDOCRINOLOGI MEDICAL GUIDELINES FOR CLINICAL PRACTICE FOR THE DIAGNOSIS AND MANAGEMENT OF THYROID NODULES--2016 UPDATE
by Gharib, Hossein and Papini, Enrico and Garber, Jeffrey R and Duick, Daniel S and Harrell, R Mack and Hegedüs, Laszlo and Paschke, Ralf and Valcavi, Roberto and Vitti, Paolo and AACE/ACE/AME Task Force on Thyroid Nodules and AACE ACE AME Task Force Thyroid No
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, ISSN 1530-891X, 05/2016, Volume 22, Issue 5, pp. 622 - 639
Thyroid nodules are detected in up to 50 to 60% of healthy subjects. Most nodules do not cause clinically significant symptoms, and as a result, the main... 
Diagnostic Techniques, Endocrine - standards | Thyroid Nodule - classification | United States | Humans | Thyroid Nodule - diagnosis | Endocrinology - organization & administration | Diagnostic Imaging - standards | Endocrinology - standards | Diagnostic Imaging - methods | Pregnancy | Biopsy, Fine-Needle | Thyroid Nodule - pathology | Thyroid Nodule - therapy | Female | Italy | ENDOCRINOLOGY & METABOLISM
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7. Full Text Preoperative Diagnosis of Benign Thyroid Nodules with Indeterminate Cytology
by Alexander, Erik K and Kennedy, Giulia C and Baloch, Zubair W and Cibas, Edmund S and Chudova, Darya and Diggans, James and Friedman, Lyssa and Kloos, Richard T and LiVolsi, Virginia A and Mandel, Susan J and Raab, Stephen S and Rosai, Juan and Steward, David L and Walsh, P. Sean and Wilde, Jonathan I and Zeiger, Martha A and Lanman, Richard B and Haugen, Bryan R
The New England Journal of Medicine, ISSN 0028-4793, 08/2012, Volume 367, Issue 8, pp. 705 - 715
A significant fraction of fine-needle aspirates obtained from thyroid nodules are read as indeterminate. A new molecular test accurately predicts whether a... 
SURGERY | MEDICINE, GENERAL & INTERNAL | FNA SAMPLES | MANAGEMENT | NEEDLE-ASPIRATION BIOPSY | MUTATIONS | CANCER | CARCINOMA | TUMORS | ACCURACY | IMMUNOHISTOCHEMISTRY | Thyroid Nodule - genetics | Diagnosis, Differential | Gene Expression | Prospective Studies | Double-Blind Method | Oligonucleotide Array Sequence Analysis | Humans | Middle Aged | Thyroid Nodule - diagnosis | RNA, Messenger - analysis | Gene Expression Profiling - methods | Male | Young Adult | Biopsy, Fine-Needle | Algorithms | Thyroid Gland - pathology | Thyroid Nodule - pathology | Sensitivity and Specificity | Adolescent | Aged, 80 and over | Adult | Female | Aged | Biomarkers, Tumor - genetics | Care and treatment | Thyroid cancer | Analysis | Diagnosis | Preoperative care | Gene expression | Methods | Surgical outcomes | Surgery | Risk assessment | Benign | Cytology | Thyroid gland | Mutation | Medical diagnosis | Investigations | Thyroid | Nodules
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8. Full Text Performance of the Afirma Gene Expression Classifier in Hürthle Cell Thyroid Nodules Differs from Other Indeterminate Thyroid Nodules
by Brauner, Eran and Holmes, Brittany J and Krane, Jeffrey F and Nishino, Michiya and Zurakowski, David and Hennessey, James V and Faquin, William C and Parangi, Sareh
Thyroid, ISSN 1050-7256, 07/2015, Volume 25, Issue 7, pp. 789 - 796
Background: The recently introduced Afirma gene expression classifier (AGEC) provides binary results (benign or suspicious) to guide management of... 
Thyroid Cancer and Nodules | DIAGNOSIS | IMPACT | NEOPLASMS | BENIGN | ENDOCRINOLOGY & METABOLISM | CARCINOMAS | CYTOLOGY | COMPARATIVE GENOMIC HYBRIDIZATION | CANCER | CLINICAL-EXPERIENCE | Thyroid Neoplasms - diagnosis | Carcinoma, Neuroendocrine - diagnosis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Thyroid Nodule - diagnosis | Adenocarcinoma, Follicular - genetics | Male | Gene Expression Profiling | Adult | Female | Retrospective Studies | Adenoma, Oxyphilic | Oxyphil Cells - metabolism | Thyroid Nodule - genetics | Diagnosis, Differential | Oxyphil Cells - pathology | Adenocarcinoma, Follicular - diagnosis | Carcinoma - diagnosis | Carcinoma, Neuroendocrine - genetics | Biopsy, Fine-Needle | Thyroid Neoplasms - genetics | Carcinoma, Papillary | Carcinoma - genetics | Aged | Cohort Studies
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9. Full Text Thyroid Nodules
by Beano, Abdallah M and Zmaili, Mohammad A and Zayed, Ayman A
The New England journal of medicine, ISSN 0028-4793, 03/2016, Volume 374, Issue 13, pp. 1294 - 1294
MEDICINE, GENERAL & INTERNAL | Female | Humans | Thyroid Nodule - diagnosis
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10. Full Text Molecular Testing for Mutations in Improving the Fine-Needle Aspiration Diagnosis of Thyroid Nodules
by Nikiforov, Yuri E and Steward, David L and Robinson-Smith, Toni M and Haugen, Bryan R and Klopper, Joshua P and Zhu, Zhaowen and Fagin, James A and Falciglia, Mercedes and Weber, Katherine and Nikiforova, Marina N
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 06/2009, Volume 94, Issue 6, pp. 2092 - 2098
Context: Thyroid nodules are common in adults, but only a small fraction of them are malignant. Fine-needle aspiration (FNA) with cytological evaluation is the... 
POINT MUTATIONS | ACTIVATION | BRAF(V600E) MUTATION | RET/PTC REARRANGEMENT | BRAF MUTATION | RAS MUTATIONS | FOLLICULAR CARCINOMA | ENDOCRINOLOGY & METABOLISM | HIGH PREVALENCE | CANCER | FEATURES | Biopsy, Fine-Needle - methods | Thyroid Nodule - genetics | Diagnosis, Differential | Molecular Diagnostic Techniques - methods | Follow-Up Studies | Humans | Thyroid Nodule - diagnosis | DNA Mutational Analysis - methods | Feasibility Studies | Algorithms | Thyroid Nodule - pathology | Sensitivity and Specificity | Thyroid Nodule - surgery
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11. Full Text Highly accurate diagnosis of cancer in thyroid nodules with follicular neoplasm/suspicious for a follicular neoplasm cytology by thyroseq V2 next-generation sequencing assay
by Nikiforov, Yuri E and Carty, Sally E and Chiosea, Simon I and Coyne, Christopher and Duvvuri, Umamaheswar and Ferris, Robert L and Gooding, William E and Hodak, Steven P and LeBeau, Shane O and Ohori, N. Paul and Seethala, Raja R and Tublin, Mitchell E and Yip, Linwah and Nikiforova, Marina N
Cancer, ISSN 0008-543X, 12/2014, Volume 120, Issue 23, pp. 3627 - 3634
BACKGROUNDFine-needle aspiration (FNA) cytology is a common approach to evaluating thyroid nodules, although 20% to 30% of FNAs have indeterminate cytology,... 
Genetics | Molecular diagnosis | Thyroid cancer | Thyroid nodules | Cytology | cytology | TERT PROMOTER MUTATIONS | FUSION | BRAF V600E MUTATION | thyroid cancer | thyroid nodules | molecular diagnosis | FORMS | SPECIMENS | IMPACT | genetics | FINE-NEEDLE-ASPIRATION | ONCOLOGY | CARCINOMAS | Thyroid Neoplasms - diagnosis | Prospective Studies | Adenocarcinoma, Follicular - pathology | Adenoma - genetics | Humans | Thyroid Nodule - diagnosis | Adenocarcinoma, Follicular - genetics | Molecular Diagnostic Techniques | Retrospective Studies | Adenoma, Oxyphilic | Carcinoma - pathology | Thyroid Nodule - genetics | Adenoma - diagnosis | Adenocarcinoma, Follicular - diagnosis | Carcinoma - diagnosis | Sequence Analysis, DNA | Biopsy, Fine-Needle | Gene Fusion - genetics | Thyroid Neoplasms - genetics | Carcinoma, Papillary | Thyroid Nodule - pathology | Adenoma - pathology | Carcinoma - genetics | Mutation | Cohort Studies | Thyroid Neoplasms - pathology | Diagnosis | Research | Methods | Cancer
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12. Full Text Management Guidelines for Children with Thyroid Nodules and Differentiated Thyroid Cancer
by Francis, Gary L and Waguespack, Steven G and Bauer, Andrew J and Angelos, Peter and Benvenga, Salvatore and Cerutti, Janete M and Dinauer, Catherine A and Hamilton, Jill and Hay, Ian D and Luster, Markus and Parisi, Marguerite T and Rachmiel, Marianna and Thompson, Geoffrey B and Yamashita, Shunichi and American Thyroid Association Guidelines Task Force
Thyroid, ISSN 1050-7256, 07/2015, Volume 25, Issue 7, pp. 716 - 759
Background: Previous guidelines for the management of thyroid nodules and cancers were geared toward adults. Compared with thyroid neoplasms in adults,... 
Special Articles | SURGICAL DISCIPLINE COMMITTEE | CENTRAL COMPARTMENT DISSECTION | POSITRON-EMISSION-TOMOGRAPHY | FINE-NEEDLE-ASPIRATION | LEVOTHYROXINE SUPPRESSIVE THERAPY | RADIOACTIVE IODINE THERAPY | ENDOCRINOLOGY & METABOLISM | TERM-FOLLOW-UP | FAMILIAL ADENOMATOUS POLYPOSIS | QUALITY-OF-LIFE | STIMULATED SERUM THYROGLOBULIN | Thyroid Neoplasms - diagnosis | United States | Adenocarcinoma, Follicular - diagnosis | Humans | Thyroid Nodule - diagnosis | Carcinoma - diagnosis | Thyroid Gland - diagnostic imaging | Thyroid Neoplasms - therapy | Biopsy, Fine-Needle | Societies, Medical | Carcinoma, Papillary | Thyroid Gland - pathology | Adenocarcinoma, Follicular - therapy | Thyroid Nodule - therapy | Adolescent | Ultrasonography | Carcinoma - therapy | Disease Management | Adenoma, Oxyphilic | Child
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13. Full Text Impact of Mutational Testing on the Diagnosis and Management of Patients with Cytologically Indeterminate Thyroid Nodules: A Prospective Analysis of 1056 FNA Samples
by Nikiforov, Yuri E and Ohori, N. Paul and Hodak, Steven P and Carty, Sally E and LeBeau, Shane O and Ferris, Robert L and Yip, Linwah and Seethala, Raja R and Tublin, Mitchell E and Stang, Michael T and Coyne, Christopher and Johnson, Jonas T and Stewart, Andrew F and Nikiforova, Marina N
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 11/2011, Volume 96, Issue 11, pp. 3390 - 3397
Context: Thyroid nodules are common in adults, but only a small fraction of them is malignant. Fine-needle aspiration (FNA) cytology provides a definitive... 
SPECIMENS | SERIES | FINE-NEEDLE-ASPIRATION | BRAF(V600E) MUTATION | SOLITARY | ENDOCRINOLOGY & METABOLISM | RISK | HIGH PREVALENCE | CARCINOMA | CANCER | LESIONS | Biopsy, Fine-Needle | Thyroid Nodule - genetics | Prospective Studies | DNA Mutational Analysis | Thyroid Gland - pathology | Thyroid Nodule - pathology | Humans | Thyroid Nodule - diagnosis | Adult | Endocrine Care
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14. Full Text Impact of the Multi-Gene ThyroSeq Next-Generation Sequencing Assay on Cancer Diagnosis in Thyroid Nodules with Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance Cytology
by Nikiforov, Yuri E and Carty, Sally E and Chiosea, Simon I and Coyne, Christopher and Duvvuri, Umamaheswar and Ferris, Robert L and Gooding, William E and LeBeau, Shane O and Ohori, N. Paul and Seethala, Raja R and Tublin, Mitchell E and Yip, Linwah and Nikiforova, Marina N
Thyroid, ISSN 1050-7256, 11/2015, Volume 25, Issue 11, pp. 1217 - 1223
Background: Fine-needle aspiration (FNA) cytology is a common approach to evaluate thyroid nodules. It offers definitive diagnosis of a benign or malignant... 
Thyroid Cancer and Nodules | MANAGEMENT | FINE-NEEDLE-ASPIRATION | BIOPSY | ENDOCRINOLOGY & METABOLISM | CYTOPATHOLOGY | FNA | TERMINOLOGY | STATE | BETHESDA SYSTEM | TUMORS | Thyroid Neoplasms - diagnosis | Thyroid Nodule - genetics | Prospective Studies | Humans | Thyroid Nodule - diagnosis | Biopsy, Fine-Needle | Thyroid Neoplasms - genetics | Thyroid Gland - pathology | Thyroid Nodule - pathology | Sensitivity and Specificity | High-Throughput Nucleotide Sequencing | Mutation | Thyroid Neoplasms - pathology
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15. Full Text The incidental thyroid nodule
by Fisher, Sarah B and Perrier, Nancy D
CA: A Cancer Journal for Clinicians, ISSN 0007-9235, 03/2018, Volume 68, Issue 2, pp. 97 - 105
Incidental thyroid nodules that are found on an imaging study performed for reasons other than thyroid pathology represent a common scenario encountered by... 
thyroid nodule | thyroid neoplasm | incidental findings | endocrine neoplasm | NUCLEAR FEATURES | GENE-EXPRESSION CLASSIFIER | GENERATION SEQUENCING ASSAY | PAPILLARY MICROCARCINOMA | POSITRON-EMISSION-TOMOGRAPHY | FINE-NEEDLE-ASPIRATION | ONCOLOGY | ENCAPSULATED FOLLICULAR VARIANT | PREOPERATIVE DIAGNOSIS | BETHESDA SYSTEM | UNDETERMINED SIGNIFICANCE/FOLLICULAR LESION | Thyroid Neoplasms - diagnosis | Thyroid Neoplasms - surgery | Diagnosis, Differential | Thyroid Function Tests | Humans | Thyroid Nodule - diagnosis | Incidental Findings | Positron-Emission Tomography - methods | Biopsy, Fine-Needle | Molecular Diagnostic Techniques | Thyroid Nodule - pathology | Thyroid Nodule - surgery | Practice Guidelines as Topic | Thyroid Neoplasms - pathology | Ultrasonography - methods
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