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Environmental Health Perspectives, ISSN 0091-6765, 04/2016, Volume 124, Issue 4, pp. 542 - 549
Journal Article
Journal Article
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 8/2009, Volume 117, Issue 8, pp. 1210 - 1218
Background: An increasing number of studies are reporting the existence of polybrominated diphenyl ethers (PBDEs) and their hydroxylated (HO) and methoxylated... 
Hormone receptors | Hormone metabolism | Receptors | Dose response relationship | Cellular metabolism | Halogenated diphenyl ethers | Plasmids | Congeners | Flame retardants | Research | Ethers | Estrogen receptor | Androgen receptor | Glucocorticoid receptor | Reporter gene assay | Brominated diphenyl ether | Thyroid hormone receptor | Chinese hamster ovary cells | glucocorticoid receptor | ESTROGEN-RECEPTORS | estrogen receptor | THYROID-HORMONE | ALPHA | brominated diphenyl ether | reporter gene assay | BETA | ENVIRONMENTAL SCIENCES | IN-VITRO | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | androgen receptor | thyroid hormone receptor | BROMINATED FLAME RETARDANTS | REPORTER GENE ASSAYS | 200 PESTICIDES | TOXICOLOGY | EXPOSURE | Androgen Receptor Antagonists | Cricetinae | Receptors, Glucocorticoid - antagonists & inhibitors | Cricetulus | Humans | Thyroid Hormone Receptors beta - antagonists & inhibitors | Estrogen Receptor alpha - antagonists & inhibitors | Thyroid Hormone Receptors alpha - antagonists & inhibitors | Receptors, Cytoplasmic and Nuclear - agonists | Halogenated Diphenyl Ethers - chemistry | Receptors, Glucocorticoid - agonists | Halogenated Diphenyl Ethers - metabolism | Androgens | Animals | Estrogen Receptor alpha - agonists | Estrogen Receptor beta - agonists | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Thyroid Hormone Receptors beta - agonists | Molecular Structure | Thyroid Hormone Receptors alpha - agonists | Estrogen Receptor beta - antagonists & inhibitors | CHO Cells | Receptors, Cytoplasmic and Nuclear - metabolism | Physiological aspects | Metabolites | Health aspects | Polybrominated biphenyls
Journal Article
The Lancet Oncology, ISSN 1470-2045, 05/2018, Volume 19, Issue 5, pp. 705 - 714
Gene fusions involving NTRK1, NTRK2, or NTRK3 (TRK fusions) are found in a broad range of paediatric and adult malignancies. Larotrectinib, a highly selective... 
ONCOLOGY | INFANTILE FIBROSARCOMA | MOLECULAR-DETECTION | RESPONSE ASSESSMENT | ACQUIRED-RESISTANCE | CONGENITAL FIBROSARCOMA | QUALITY-OF-LIFE | KINASE INHIBITOR LOXO-101 | TROPOMYOSIN | SOFT-TISSUE SARCOMA | MESOBLASTIC NEPHROMA | Age Factors | Discoidin Domain Receptor 2 - antagonists & inhibitors | United States | Humans | Receptor, trkA - antagonists & inhibitors | Child, Preschool | Infant | Male | Receptor, trkB - genetics | Antineoplastic Agents - administration & dosage | Protein Kinase Inhibitors - adverse effects | Young Adult | Membrane Glycoproteins - antagonists & inhibitors | Neoplasms - genetics | Time Factors | Antineoplastic Agents - adverse effects | Receptor, trkB - antagonists & inhibitors | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Female | Biomarkers, Tumor - antagonists & inhibitors | Child | Discoidin Domain Receptor 2 - genetics | Pyrazoles - adverse effects | Drug Administration Schedule | Administration, Oral | Pyrimidines - administration & dosage | Gene Fusion | Treatment Outcome | Membrane Glycoproteins - genetics | Neoplasms - drug therapy | Protein Kinase Inhibitors - administration & dosage | Pyrazoles - administration & dosage | Receptor Protein-Tyrosine Kinases - genetics | Adolescent | Pyrimidines - adverse effects | Receptor, trkA - genetics | Biomarkers, Tumor - genetics | Neoplasms - pathology | Genetic research | Pediatrics | Analysis
Journal Article
Journal Article
Journal Article
Bulletin of the Korean Chemical Society, ISSN 1229-5949, 03/2019, Volume 40, Issue 3, pp. 207 - 213
A RET (Rearranged during transfection) kinase belongs to a receptor tyrosine kinase family. It plays a major role in development, maturation, survival, and... 
RET | Docking | RET kinase antagonists | Cancer | CoMFA | CoMSIA | PATHWAYS | DOMAIN | VALIDATION | CHEMISTRY, MULTIDISCIPLINARY | THYROID-CANCER | NEOPLASIA | INHIBITORS | MUTATIONS | PROTOONCOGENE | DERIVATIVES | BINDING
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2013, Volume 288, Issue 23, pp. 16476 - 16483
Journal Article
Journal Article