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1. Nuclear receptors
: a practical approach
by Picard, Didier
1999, Practical approach series, ISBN 9780199637430, Volume 207, xviii, 285
Receptors, Steroid | Receptors | Transcription Factors | Receptors, Cytoplasmic and Nuclear | Steroid hormones | Nuclear receptors (Biochemistry)
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2. Full Text Nuclear Hormone Receptor Activity of Polybrominated Diphenyl Ethers and Their Hydroxylated and Methoxylated Metabolites in Transactivation Assays Using Chinese Hamster Ovary Cells
by Hiroyuki Kojima and Shinji Takeuchi and Naoto Uramaru and Kazumi Sugihara and Takahiko Yoshida and Shigeyuki Kitamura
Environmental Health Perspectives, ISSN 0091-6765, 8/2009, Volume 117, Issue 8, pp. 1210 - 1218
Background: An increasing number of studies are reporting the existence of polybrominated diphenyl ethers (PBDEs) and their hydroxylated (HO) and methoxylated... 
Hormone receptors | Hormone metabolism | Receptors | Dose response relationship | Cellular metabolism | Halogenated diphenyl ethers | Plasmids | Congeners | Flame retardants | Research | Ethers | Estrogen receptor | Androgen receptor | Glucocorticoid receptor | Reporter gene assay | Brominated diphenyl ether | Thyroid hormone receptor | Chinese hamster ovary cells | glucocorticoid receptor | ESTROGEN-RECEPTORS | estrogen receptor | THYROID-HORMONE | ALPHA | brominated diphenyl ether | reporter gene assay | BETA | ENVIRONMENTAL SCIENCES | IN-VITRO | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | androgen receptor | thyroid hormone receptor | BROMINATED FLAME RETARDANTS | REPORTER GENE ASSAYS | 200 PESTICIDES | TOXICOLOGY | EXPOSURE | Androgen Receptor Antagonists | Cricetinae | Receptors, Glucocorticoid - antagonists & inhibitors | Cricetulus | Humans | Thyroid Hormone Receptors beta - antagonists & inhibitors | Estrogen Receptor alpha - antagonists & inhibitors | Thyroid Hormone Receptors alpha - antagonists & inhibitors | Receptors, Cytoplasmic and Nuclear - agonists | Halogenated Diphenyl Ethers - chemistry | Receptors, Glucocorticoid - agonists | Halogenated Diphenyl Ethers - metabolism | Androgens | Animals | Estrogen Receptor alpha - agonists | Estrogen Receptor beta - agonists | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Thyroid Hormone Receptors beta - agonists | Molecular Structure | Thyroid Hormone Receptors alpha - agonists | Estrogen Receptor beta - antagonists & inhibitors | CHO Cells | Receptors, Cytoplasmic and Nuclear - metabolism | Physiological aspects | Metabolites | Health aspects | Polybrominated biphenyls
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3. Nuclear hormone receptors
: molecular mechanisms, cellular functions, clinical abnormalities
by Parker, Malcolm G
1991, ISBN 0125450729, xvii, 404 p., [1] leaf of plates
Hormone receptors | Endocrine glands | Diseases
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4. Full Text Structural overview of the nuclear receptor superfamily: Insights into physiology and therapeutics
by Huang, Pengxiang and Chandra, Vikas and Rastinejad, Fraydoon
Annual Review of Physiology, ISSN 0066-4278, 03/2009, Volume 72, Issue 1, pp. 247 - 272
As ligand-regulated transcription factors, the nuclear hormone receptors are nearly ideal drug targets, with internal pockets that bind to hydrophobic,... 
Nuclear receptor | Protein-ligand interactions | Drug discovery | protein-ligand interactions | PHYSIOLOGY | ESTROGEN-RECEPTOR | RAY CRYSTAL-STRUCTURE | GLUCOCORTICOID-RECEPTOR | drug discovery | HUMAN ANDROGEN RECEPTOR | nuclear receptor | FARNESOID-X-RECEPTOR | REV-ERB-ALPHA | PPAR-GAMMA | LIGAND-BINDING DOMAIN | THYROID-HORMONE RECEPTOR | STRUCTURE-BASED DESIGN | Receptors, Thyroid Hormone - drug effects | Amino Acid Sequence | Protein Structure, Secondary | Receptors, Cytoplasmic and Nuclear - drug effects | Humans | Drug Therapy | Nuclear Proteins - metabolism | Receptors, Cytoplasmic and Nuclear - physiology | Receptors, Steroid - drug effects | Nuclear Proteins - chemistry | Drug Discovery | Receptors, Thyroid Hormone - physiology | Receptors, Estrogen - drug effects | Animals | Receptors, Steroid - physiology | Receptors, Cytoplasmic and Nuclear - chemistry | Lipid Metabolism - drug effects | Nuclear Proteins - physiology | Lipid Metabolism - physiology | Receptors, Estrogen - physiology | Drugs | Hormone receptors | Drug delivery systems | Ligand binding (Biochemistry) | Research | Vehicles
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5. Full Text Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia
by Mullican, SE and Zhang, S and Konopleva, M and Ruvolo, V and Andreeff, M and Milbrandt, J and Conneely, OM
NATURE MEDICINE, ISSN 1078-8956, 06/2007, Volume 13, Issue 6, pp. 730 - 735
Nur77 (NR4A1) and Nor-1 (NR4A3) are highly homologous orphan nuclear receptors(1,2) that regulate the transcription of overlapping target genes(2),(3). The... 
MEDICINE, RESEARCH & EXPERIMENTAL | PROGENITORS | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ORPHAN RECEPTOR | IDENTIFICATION | MICE LACKING | CELL BIOLOGY | C/EBP-ALPHA | NGFI-B | NUR77 | TRANSCRIPTION FACTOR | EXPRESSION | Receptors, Cytoplasmic and Nuclear - deficiency | Humans | Leukemia, Myeloid - genetics | Nerve Tissue Proteins - deficiency | Transcription Factors - deficiency | Nuclear Receptor Subfamily 4, Group A, Member 1 | Receptors, Cytoplasmic and Nuclear - biosynthesis | Receptors, Steroid - antagonists & inhibitors | Receptors, Thyroid Hormone - antagonists & inhibitors | DNA-Binding Proteins - deficiency | Leukemia, Myeloid - pathology | Receptors, Steroid - biosynthesis | Receptors, Thyroid Hormone - genetics | Receptors, Steroid - deficiency | Acute Disease | DNA-Binding Proteins - physiology | Nerve Tissue Proteins - physiology | Transcription Factors - physiology | Blast Crisis - pathology | DNA-Binding Proteins - antagonists & inhibitors | Mice, Inbred C57BL | Receptors, Thyroid Hormone - biosynthesis | Receptors, Cytoplasmic and Nuclear - physiology | Transcription Factors - antagonists & inhibitors | Transcription Factors - biosynthesis | Receptors, Cytoplasmic and Nuclear - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Receptors, Thyroid Hormone - physiology | Down-Regulation - genetics | Mice, Knockout | Animals | Receptors, Steroid - genetics | Leukemia, Myeloid - metabolism | Receptors, Steroid - physiology | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Receptors, Thyroid Hormone - deficiency | Blast Crisis - genetics | Mice | DNA-Binding Proteins - biosynthesis
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6. Full Text An in vitro model for evaluating peripheral regulation of growth in fish: Effects of 17β-estradiol and testosterone on the expression of growth hormone receptors, insulin-like growth factors, and insulin-like growth factor type 1 receptors in rainbow trout ( Oncorhynchus mykiss )
by Norbeck, Lindsey A and Sheridan, Mark A
General and Comparative Endocrinology, ISSN 0016-6480, 2011, Volume 173, Issue 2, pp. 270 - 280
Highlights â–º 17β-Estradiol (E2) inhibits growth hormone receptor (GHR) expression in liver but not gill. â–º E2 inhibits IGF-1 and IGF-2 expression in liver. â–º... 
Endocrinology & Metabolism | Insulin-like growth factor receptor | Testosterone | Growth hormone–insulin-like growth factor system | Growth hormone receptor | Rainbow trout | 17β-Estradiol | Insulin-like growth factor-1 | Insulin-like growth factor-2 | Growth hormone-insulin-like growth factor system | SALMO-GAIRDNERI | IGF-I | GONADAL-STEROID HORMONES | FACTOR AXIS | BONY FISH | SEX STEROIDS | SOMATOSTATIN | THYROID-HORMONES | ENDOCRINOLOGY & METABOLISM | SEAWATER ADAPTATION | TILAPIA OREOCHROMIS-MOSSAMBICUS | 17 beta-Estradiol | Oncorhynchus mykiss - metabolism | Receptor, IGF Type 1 - metabolism | Receptors, Somatotropin - metabolism | Gene Expression - drug effects | Gene Expression - genetics | Oncorhynchus mykiss - genetics | Testosterone - pharmacology | Receptor, IGF Type 1 - genetics | Receptors, Somatotropin - genetics | Animals | Somatomedins - genetics | Estradiol - pharmacology | Somatomedins - metabolism
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7. Full Text Structure of the retinoid X receptor α-liver X receptor β (RXRα-LXRβ) heterodimer on DNA
by Lou, Xiaohua and Toresson, Gudrun and Benod, Cindy and Suh, Ji Ho and Philips, Kevin J and Webb, Paul and Gustafsson, Jan-Ake and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Nature Structural and Molecular Biology, ISSN 1545-9993, 2014, Volume 21, Issue 3, pp. 277 - 281
Nuclear receptors (NRs) are conditional transcription factors with common multidomain organization that bind diverse DNA elements. How DNA sequences influence... 
ACTIVATION | AQUAPORIN-1 EXPRESSION | THYROID-HORMONE | NUCLEAR RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIRECT REPEATS | CELL BIOLOGY | BIOPHYSICS | CONSTITUTIVE ANDROSTANE RECEPTOR | RESPONSE ELEMENTS | MICE | LOW-RESOLUTION STRUCTURES | BINDING | Protein Structure, Tertiary | Promoter Regions, Genetic | Zinc Fingers | Humans | Protein Multimerization | Models, Molecular | Retinoid X Receptor alpha - chemistry | Orphan Nuclear Receptors - genetics | DNA - chemistry | Orphan Nuclear Receptors - chemistry | Liver X Receptors | Escherichia coli - metabolism | Retinoid X Receptor alpha - genetics | Protein Binding | Ligands | Mutation | DNA, Complementary - metabolism
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8. Full Text Combinatorial roles of nuclear receptors in inflammation and immunity
by Ogawa, Sumito and Glass, Christopher K
Nature Reviews Immunology, ISSN 1474-1733, 01/2006, Volume 6, Issue 1, pp. 44 - 55
Members of the nuclear-receptor superfamily have well-documented regulatory effects on inflammatory processes. Recent work has highlighted the roles of... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | GLUCOCORTICOID-RECEPTOR | RETINOIC ACID | PPAR-GAMMA | LIGAND-BINDING DOMAIN | IMMUNOLOGY | PROLIFERATOR-ACTIVATED-RECEPTOR | THYROID-HORMONE RECEPTOR | NF-KAPPA-B | LIVER-X-RECEPTORS | HUMAN ENDOTHELIAL-CELLS | Cell Nucleus - immunology | Peroxisome Proliferator-Activated Receptors - genetics | DNA-Binding Proteins - physiology | Peroxisome Proliferator-Activated Receptors - physiology | Immunity, Cellular - genetics | Humans | Receptors, Glucocorticoid - biosynthesis | Peroxisome Proliferator-Activated Receptors - biosynthesis | Receptors, Cytoplasmic and Nuclear - physiology | Inflammation - immunology | Receptors, Cytoplasmic and Nuclear - genetics | Receptors, Cytoplasmic and Nuclear - biosynthesis | DNA-Binding Proteins - genetics | Inflammation - therapy | Inflammation - metabolism | Animals | Cell Nucleus - metabolism | Liver X Receptors | Receptors, Glucocorticoid - genetics | Orphan Nuclear Receptors | DNA-Binding Proteins - biosynthesis | Receptors, Glucocorticoid - physiology
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9. Full Text Effect of hypothyroidism on the expression of nuclear receptors and their co-regulators in mammary gland during lactation in the rat
by Campo Verde Arboccó, Fiorella and Sasso, Corina V and Nasif, Daniela L and Hapon, María Belén and Jahn, Graciela A
Molecular and Cellular Endocrinology, ISSN 0303-7207, 09/2015, Volume 412, Issue C, pp. 26 - 35
Thyroid hormones (TH) regulate mammary function. Hypothyroidism (HypoT) has deleterious effects on lactation, litter growth and survival. We analyzed the... 
Co-regulators | Mammary gland | Lactation | Hypothyroidism | Nuclear receptors | DOWN-REGULATION | I DEIODINASE | CELL BIOLOGY | ESTROGEN RESPONSE ELEMENT | BREAST-CANCER CELLS | GROWTH-HORMONE | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | THYROID-HORMONE RECEPTORS | OXYTOCIN RECEPTOR | PROGESTERONE-RECEPTOR | LATE-PREGNANT RATS | Hypothyroidism - chemically induced | Hypothyroidism - metabolism | Receptors, Estrogen - metabolism | Retinoid X Receptor alpha - metabolism | Rats, Wistar | Receptors, Oxytocin - genetics | Nuclear Receptor Co-Repressor 1 - genetics | Nuclear Receptor Coactivator 2 - metabolism | Receptors, Progesterone - genetics | Propylthiouracil | Nuclear Receptor Coactivator 1 - metabolism | Receptors, Progesterone - metabolism | Nuclear Receptor Coactivator 1 - genetics | Protein Isoforms - metabolism | Receptors, Thyroid Hormone - genetics | Female | Gene Expression | Receptors, Estrogen - genetics | Receptors, Thyroid Hormone - metabolism | Receptors, Oxytocin - metabolism | Animals | Mammary Glands, Animal - metabolism | Nuclear Receptor Co-Repressor 1 - metabolism | Retinoid X Receptor alpha - genetics | Nuclear Receptor Coactivator 2 - genetics | Protein Isoforms - genetics | Cell differentiation | Thyroid hormones
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10. Full Text Nuclear receptors in neural stem/progenitor cell homeostasis
by Gkikas, Dimitrios and Tsampoula, Matina and Politis, Panagiotis K
Cellular and Molecular Life Sciences, ISSN 1420-682X, 11/2017, Volume 74, Issue 22, pp. 4097 - 4120
In the central nervous system, embryonic and adult neural stem/progenitor cells (NSCs) generate the enormous variety and huge numbers of neuronal and glial... 
Biomedicine, general | Biochemistry, general | Agonists/antagonists | Brain development | Neurogenesis | Glucocorticoid | Cell Biology | Life Sciences | Neurological diseases | Life Sciences, general | Drug targets | Astrogliogenesis | Retinoic acid | PROLIFERATOR-ACTIVATED RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | VITAMIN-D-RECEPTOR | ORPHAN RECEPTOR | STEROIDOGENIC FACTOR-I | MINERALOCORTICOID RECEPTOR | CELL BIOLOGY | GLUCOCORTICOID-RECEPTOR | EMBRYONIC STEM-CELLS | CENTRAL-NERVOUS-SYSTEM | RETINOID-X-RECEPTOR | THYROID-HORMONE RECEPTOR | Receptors, Estrogen - metabolism | Receptors, Mineralocorticoid - metabolism | Humans | Receptors, Glucocorticoid - metabolism | Receptors, Calcitriol - metabolism | Neural Stem Cells - cytology | Receptors, Thyroid Hormone - metabolism | Animals | Nervous System Diseases - metabolism | Cell Differentiation | Neural Stem Cells - metabolism | Nervous System Diseases - pathology | Receptors, Cytoplasmic and Nuclear - metabolism | Medical research | Embryonic development | Nervous system diseases | Corticosteroids | Neurons | Homeostasis | Medicine, Experimental | Brain | Spinal cord | Regulators | Pathogenesis | Central nervous system | Nervous system | Glial cells | Nuclear receptors | Orphan nuclear receptors | Neuronal-glial interactions | Embryonic growth stage | Receptors | Embryogenesis | Molecular modelling | Cells (biology) | Stem cells | Neural stem cells | Receptor mechanisms | Aberration | Bile | Structure-function relationships
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