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Aquatic Toxicology, ISSN 0166-445X, 04/2012, Volume 110-111, pp. 141 - 148
► Thyroid endocrine disruption was investigated in zebrafish larvae following exposure of embryos to BDE-209. ► Both T4 and T3 levels were changed by BDE-209... 
Thyroid endocrine disruption | Zebrafish larvae | Hypothalamic–Pituitary–Thyroid axis | Bioconcentration and metabolism | BDE-209 | Gene transcription | Hypothalamic-Pituitary-Thyroid axis | SPRAGUE-DAWLEY RATS | POLYBROMINATED DIPHENYL ETHERS | HORMONE RECEPTORS | PEARL RIVER DELTA | IN-VITRO | MARINE & FRESHWATER BIOLOGY | GENE-EXPRESSION | TOXICOLOGY | PIMEPHALES-PROMELAS | DEVELOPMENTAL EXPOSURE | SOUTH CHINA | POLYCHLORINATED-BIPHENYLS | Up-Regulation | Thyrotropin - genetics | Embryo, Nonmammalian - metabolism | RNA, Messenger - metabolism | Zebrafish - embryology | Embryo, Nonmammalian - drug effects | Thyroid Hormone Receptors beta - genetics | Halogenated Diphenyl Ethers - toxicity | Triiodothyronine - metabolism | Triiodothyronine - genetics | Endocrine System - metabolism | Iodide Peroxidase - metabolism | Endocrine System - drug effects | Thyroid Gland - drug effects | Thyroid Hormone Receptors beta - metabolism | Endocrine Disruptors - metabolism | Thyrotropin - metabolism | Endocrine Disruptors - toxicity | Halogenated Diphenyl Ethers - metabolism | Water Pollutants, Chemical - metabolism | Animals | Water Pollutants, Chemical - toxicity | Thyroxine - metabolism | Thyroxine - genetics | Iodide Peroxidase - genetics | Thyroid Gland - metabolism | Corticotropin releasing hormone | Pituitary hormones | Genes | Physiological aspects | ACTH | Glycoproteins | Genetic transcription | Thyroid hormones | Hormones | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2010, Volume 120, Issue 6, pp. 2206 - 2217
Journal Article
Journal Article
Endocrinology, ISSN 0013-7227, 02/2016, Volume 157, Issue 2, pp. 774 - 787
Severe thyroid hormone (TH) deficiency during critical phases of brain development results in irreversible neurological and cognitive impairments. The... 
PROPYLTHIOURACIL PTU | MESSENGER-RNA | GYRUS IN-VIVO | ENDOCRINOLOGY & METABOLISM | NEUROTROPHIC FACTOR BDNF | GESTATIONAL MATERNAL HYPOTHYROXINEMIA | LONG-TERM POTENTIATION | DENTATE GYRUS | SYNAPTIC PLASTICITY | INCREASED AUTISM RISK | NERVE GROWTH-FACTOR | TOR Serine-Threonine Kinases - metabolism | Cytoskeletal Proteins - genetics | Rats, Long-Evans | Congenital Hypothyroidism - chemically induced | Neuronal Plasticity - drug effects | Male | Neuronal Plasticity - physiology | TOR Serine-Threonine Kinases - genetics | Triiodothyronine - drug effects | Behavior, Animal - drug effects | Brain-Derived Neurotrophic Factor - metabolism | Kruppel-Like Transcription Factors - drug effects | TOR Serine-Threonine Kinases - drug effects | Disease Models, Animal | Hippocampus - embryology | Maze Learning - physiology | Propylthiouracil - toxicity | Rats | Behavior, Animal - physiology | Nerve Growth Factor - genetics | Antithyroid Agents - toxicity | Nerve Tissue Proteins - drug effects | Thyroxine - metabolism | Neurotrophin 3 - drug effects | Kruppel-Like Transcription Factors - genetics | Brain-Derived Neurotrophic Factor - genetics | Neurotrophin 3 - genetics | Early Growth Response Protein 1 - drug effects | Brain-Derived Neurotrophic Factor - drug effects | Triiodothyronine - metabolism | Kruppel-Like Transcription Factors - metabolism | Early Growth Response Protein 1 - genetics | Cytoskeletal Proteins - metabolism | Female | Cytoskeletal Proteins - drug effects | Nerve Growth Factor - drug effects | Congenital Hypothyroidism - embryology | Severity of Illness Index | Nerve Growth Factor - metabolism | Conditioning (Psychology) - drug effects | Conditioning (Psychology) - physiology | Triiodothyronine - deficiency | Congenital Hypothyroidism - metabolism | Maze Learning - drug effects | Nerve Tissue Proteins - genetics | Prenatal Exposure Delayed Effects - metabolism | Nerve Tissue Proteins - metabolism | Pregnancy | Thyroxine - drug effects | Fear | Hippocampus - metabolism | Animals | Neurotrophin 3 - metabolism | Thyroxine - deficiency | Early Growth Response Protein 1 - metabolism | Prenatal Exposure Delayed Effects - chemically induced | Index Medicus | Abridged Index Medicus
Journal Article
Journal of clinical investigation, ISSN 0021-9738, 2014, Volume 124, Issue 5, pp. 1987 - 1999
Journal Article
Endocrinology, ISSN 0013-7227, 03/2016, Volume 157, Issue 3, pp. 1211 - 1221
The hypothalamic-pituitary-thyroid axis is governed by hypophysiotropic TRH-synthesizing neurons located in the hypothalamic paraventricular nucleus under... 
Immunohistochemistry | Thyroid Nuclear Factor 1 | Thyrotropin, beta Subunit - genetics | Brain - embryology | Pituitary Gland - metabolism | Humans | Ependymoglial Cells - metabolism | Gene Expression Regulation, Developmental - genetics | RNA, Messenger - metabolism | Transcription Factors - drug effects | Brain - metabolism | Thyrotropin-Releasing Hormone - metabolism | In Situ Hybridization | Triiodothyronine - metabolism | Triiodothyronine - drug effects | Iodide Peroxidase - metabolism | Neurons - metabolism | Nuclear Proteins - drug effects | Hypothalamus - drug effects | Neurons - drug effects | Paraventricular Hypothalamic Nucleus - embryology | Real-Time Polymerase Chain Reaction | RNA, Messenger - drug effects | Hypothalamus - embryology | Hypothalamo-Hypophyseal System - embryology | Gene Expression Regulation, Developmental - drug effects | Nuclear Proteins - metabolism | Ependymoglial Cells - drug effects | Reverse Transcriptase Polymerase Chain Reaction | Chick Embryo | Hypothalamo-Hypophyseal System - metabolism | Brain - drug effects | Transcription Factors - metabolism | Paraventricular Hypothalamic Nucleus - drug effects | Animals | Hypothalamus - metabolism | Thyroxine - metabolism | Paraventricular Hypothalamic Nucleus - metabolism | Cell Line, Tumor | Iodide Peroxidase - drug effects | Feedback, Physiological - drug effects | Feedback, Physiological - physiology | Thyroid Gland - metabolism | Pituitary Gland - drug effects | Thyroxine - pharmacology | Index Medicus | Abridged Index Medicus
Journal Article
Ecotoxicology and Environmental Safety, ISSN 0147-6513, 10/2018, Volume 161, pp. 374 - 382
Journal Article
Journal of Endocrinology, ISSN 0022-0795, 2014, Volume 221, Issue 3, pp. 415 - 427
In general, 3,5-diiodothyronine (3,5-T2) increases the resting metabolic rate and oxygen consumption, exerting short-term beneficial metabolic effects on rats... 
TSH | Deiodinase | Thyroid hormone metabolism | 3,5-T2 | RAT SKELETAL-MUSCLE | OXYGEN-CONSUMPTION | thyroid hormone metabolism | HIGH-FAT-DIET | IODOTHYRONINE DEIODINASE | RAPID STIMULATION | deiodinase | INDUCED INSULIN-RESISTANCE | CYTOCHROME-C-OXIDASE | IN-VIVO | TYPE-2 DEIODINASE | ENDOCRINOLOGY & METABOLISM | RESTING METABOLIC-RATE | Hypothyroidism - metabolism | Receptors, Thyrotropin - genetics | Rats, Wistar | NADPH Oxidases - metabolism | Thyroxine - blood | Immunoblotting | Male | Basal Metabolism - drug effects | Kidney - metabolism | Liver - drug effects | Iodide Peroxidase - metabolism | Diiodothyronines - pharmacology | NADPH Oxidases - genetics | Hypothyroidism - genetics | Hypothalamo-Hypophyseal System - physiopathology | Thyroid Gland - drug effects | Thyrotropin - blood | Diiodothyronines - administration & dosage | Hypothalamo-Hypophyseal System - drug effects | Flavoproteins - metabolism | Kidney - drug effects | Flavoproteins - genetics | Receptors, Thyrotropin - metabolism | Liver - metabolism | Rats | NADPH Oxidase 4 | Reverse Transcriptase Polymerase Chain Reaction | Hypothalamo-Hypophyseal System - metabolism | Triiodothyronine - blood | Animals | Iodides - metabolism | Oxygen Consumption - drug effects | Hypothyroidism - blood | Dual Oxidases | Thyroid Gland - metabolism | Thyroid Gland - physiopathology | Index Medicus | Research
Journal Article
Endocrinology, ISSN 0013-7227, 01/2016, Volume 157, Issue 1, pp. 23 - 38
Thyroid hormone (TH) and autophagy share similar functions in regulating skeletal muscle growth, regeneration, and differentiation. Although TH recently has... 
CELLS | RAT | METABOLISM | PGC-1-ALPHA | SUSTAIN EXERCISE | IN-VIVO | ADAPTATION | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | DUCHENNE MUSCULAR-DYSTROPHY | AMPK ACTIVATION | AMP-Activated Protein Kinases - metabolism | Reactive Oxygen Species - metabolism | Microtubule-Associated Proteins - genetics | TOR Serine-Threonine Kinases - metabolism | Microtubule-Associated Proteins - metabolism | Mitochondria, Muscle - metabolism | Male | Muscle, Skeletal - metabolism | Muscle, Skeletal - cytology | Autophagy - drug effects | Reactive Oxygen Species - agonists | Autophagy-Related Protein-1 Homolog | TOR Serine-Threonine Kinases - antagonists & inhibitors | Myoblasts, Skeletal - cytology | Triiodothyronine - metabolism | RNA Interference | Muscle, Skeletal - drug effects | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Protein-Serine-Threonine Kinases - metabolism | Myoblasts, Skeletal - metabolism | Triiodothyronine - pharmacology | Cell Line | Mice, Inbred C57BL | Muscle, Skeletal - ultrastructure | Microtubule-Associated Proteins - antagonists & inhibitors | Transcription Factors - genetics | AMP-Activated Protein Kinases - chemistry | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Animals | Mitochondrial Dynamics - drug effects | Autophagy-Related Protein 5 | Signal Transduction - drug effects | Oxygen Consumption - drug effects | Thyroxine - metabolism | Mitochondria, Muscle - ultrastructure | Mitochondria, Muscle - drug effects | Protein-Serine-Threonine Kinases - chemistry | Kinetics | Transcription Factors - agonists | Myoblasts, Skeletal - drug effects | Myoblasts, Skeletal - ultrastructure | Thyroxine - pharmacology | Index Medicus | Abridged Index Medicus
Journal Article
Thyroid, ISSN 1050-7256, 08/2017, Volume 27, Issue 8, pp. 192 - 1098
Background: The possibility that the intrinsic genomic activity of thyroxine (T4) is of physiological relevance has been frequently hypothesized. It might... 
Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action | N2a cells | Rgs4 | Zcchc12 | astrocytes | cerebrocortical cells | thyroxine activity | MOUSE CEREBRAL-CORTEX | RAT BROWN ADIPOCYTES | PITUITARY-RESISTANCE | ISOFORM | GROWTH | ENDOCRINOLOGY & METABOLISM | THYROID-HORMONE-RECEPTOR | L-TRIIODOTHYRONINE | NONGENOMIC ACTIONS | Neuroblastoma - enzymology | Avian Proteins - agonists | Gene Expression Regulation, Neoplastic | Neurons - cytology | Astrocytes - enzymology | Neoplasm Proteins - metabolism | Cerebral Cortex - cytology | Cerebral Cortex - metabolism | Triiodothyronine - metabolism | Thyroid Hormone Receptors alpha - genetics | Gene Expression Regulation, Developmental | Iodide Peroxidase - metabolism | Neurons - metabolism | Neoplasm Proteins - genetics | Neuroblastoma - pathology | Astrocytes - cytology | Recombinant Proteins - metabolism | Cell Line | Avian Proteins - metabolism | Cerebral Cortex - enzymology | Cells, Cultured | Recombinant Proteins - chemistry | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Embryo, Mammalian - cytology | Chickens | Neurons - enzymology | Thyroxine - metabolism | Thyroid Hormone Receptors alpha - metabolism | Mice | Neuroblastoma - metabolism | Iodide Peroxidase - genetics | Thyroid Hormone Receptors alpha - agonists | Astrocytes - metabolism | Avian Proteins - genetics | Index Medicus
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 05/2009, Volume 296, Issue 5, pp. 980 - 991
3,5,3′-Triiodo-l-thyronine (T3), but not l-thyroxine (T4), activated Src kinase and, downstream, phosphatidylinositol 3-kinase (PI3-kinase) by means of an αvβ3... 
Integrin α | Intracellular hormone receptor trafficking | Extracellular signal-regulated kinase 1/2 | Mitogen-activated protein kinase | Src kinase | Thyroid hormone | Glioblastoma cells | Phosphatidylinositol 3-kinase | GLIOMA-CELLS | PHYSIOLOGY | thyroid hormone | CANCER CELLS | ALVEOLAR EPITHELIAL-CELLS | SURFACE RECEPTOR | PLASMA-MEMBRANE | NUCLEAR RECEPTOR | CELL BIOLOGY | mitogen-activated protein kinase | THYROID-HORMONE PROMOTES | integrin alpha(v)beta | EPIDERMAL-GROWTH-FACTOR | intracellular hormone receptor trafficking | extracellular signal-regulated kinase 1/2 | glioblastoma cells | NONGENOMIC ACTIONS | phosphatidylinositol 3-kinase | MAP Kinase Signaling System - physiology | Humans | Brain Neoplasms - pathology | Cytoplasm - metabolism | Protein Transport - physiology | Phosphatidylinositol 3-Kinases - metabolism | Protein Transport - drug effects | Brain Neoplasms - metabolism | Integrin alphaVbeta3 - metabolism | Glioma - metabolism | Cell Nucleus - metabolism | Transfection | Triiodothyronine - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Glioma - pathology | Mitogen-Activated Protein Kinase 1 - genetics | Triiodothyronine - pharmacology | Mitogen-Activated Protein Kinase 3 - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Cell Division - drug effects | Cell Division - physiology | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Thyroxine - metabolism | Cell Line, Tumor | Thyroid Hormone Receptors alpha - metabolism | Thyroxine - pharmacology | Mitogen-Activated Protein Kinase 1 - metabolism | Studies | Peptides | Cell division | Mathematical models | Kinases | Cells | Binding sites | Index Medicus
Journal Article
Endocrinology, ISSN 0013-7227, 04/2010, Volume 151, Issue 4, pp. 1633 - 1642
Journal Article