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ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, ISSN 1433-7266, 03/2017, Volume 232, Issue 2, pp. 173 - 176
C34H49NO5S, monoclinic, P2(1)(no. 4), a = 14.4605(4)angstrom, b = 9.9703(4)angstrom, c = 22.7599(7)angstrom, beta = 94.799(3)angstrom; V = 3269.90 angstrom(3),... 
TIAMULIN | CRYSTALLOGRAPHY
Journal Article
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, ISSN 0066-4804, 07/2006, Volume 50, Issue 7, pp. 2500 - 2505
A novel multidrug resistance phenotype mediated by the Cfr rRNA methyltransferase is observed in Staphylococcus aureus and Escherichia coli. The cfr gene has... 
LINKING | CHLORAMPHENICOL | BACTERIAL RIBOSOME | MECHANISM | TIAMULIN | GENE | PEPTIDYL TRANSFERASE CENTER | MACROLIDE | FLORFENICOL | FEXA | MICROBIOLOGY | PHARMACOLOGY & PHARMACY
Journal Article
Journal of Chromatography B, ISSN 1570-0232, 01/2018, Volume 1072, pp. 142 - 148
Previously reported LC–MS methods for quantifying 8-α-hydroxy-mutilin (a marker residue of tiamulin) in tissues all used a pseudo MRM transition (from... 
Tiamulin | Rabbit | Tissue | 8-α-hydroxy-mutilin | LC–MS | CHEMISTRY, ANALYTICAL | ANTIBIOTICS | TIAMULIN METABOLITES | SWINE | BIOCHEMICAL RESEARCH METHODS | VALIDATION | TANDEM MASS-SPECTROMETRY | LC-MS/MS | LC-MS | LIQUID-CHROMATOGRAPHY | MATRICES | 8-alpha-hydroxy-mutilin | RESIDUES | WATER
Journal Article
Journal of Chromatographic Science, ISSN 0021-9665, 08/2018, Volume 56, Issue 7, pp. 604 - 610
Abstract A simple, sensitive and reproducible high-performance liquid chromatography method was developed and validated for the determination of... 
CHEMISTRY, ANALYTICAL | ANTIBIOTICS | TIAMULIN | EFFICACY | BIOCHEMICAL RESEARCH METHODS
Journal Article
Microbial Pathogenesis, ISSN 0882-4010, 02/2019, Volume 127, pp. 202 - 207
This study assessed the antimicrobial activity of 14-O-[(4,6-Diaminopyrimidine-2-yl) thioacetyl] mutilin (DPTM), a novel pleuromutilin candidate with a... 
Antibacterial activity | Mice | DPTM | Pasteurella multocida | CHALLENGE | PHARMACOKINETICS | TIAMULIN | MICROBIOLOGY | INFECTION | IMMUNOLOGY | DERIVATIVES
Journal Article
Journal of Veterinary Pharmacology and Therapeutics, ISSN 0140-7783, 07/2019, Volume 42, Issue 4, pp. 447 - 451
The bioavailability and pharmacokinetic disposition of tiamulin in broiler chicken were investigated after administration through the crop, drinking water, and... 
pharmacokinetics | chronic respiratory disease | bioavailability | broiler chicken | tiamulin | DOXYCYCLINE | PHARMACOLOGY & PHARMACY | VETERINARY SCIENCES | Chromatography
Journal Article
Applied and Environmental Microbiology, ISSN 0099-2240, 06/2017, Volume 83, Issue 12
This study describes the results of a randomized clinical trial investigating the effect of oxytetracycline treatment dose and mode of administration on the... 
Cefotaxime | Body weight | Clinical trials | Diarrhea | Effects | Coliforms | Oxytetracycline | Tiamulin | Antibiotics | Ampicillin | Sulfonamides | Antibiotic resistance | Bacteria | Drug dosages | Strains (organisms)
Journal Article
Journal of Animal Science, ISSN 0021-8812, 07/2019, Volume 97, Issue Supplement_2, pp. 158 - 158
Abstract Tiamulin hydrogen fumarate is commonly used in water to treat enteric or respiratory disease caused by susceptible pathogens in nursery pigs. This... 
Water | Pathogens | Water treatment | Drinking water | Weaning | Animal diseases | Drainage | Tiamulin | Hogs | Respiratory diseases | Barns | Water intake | Water consumption | Water intakes | Age | Hydrogen ion concentration | Pens
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2018, Volume 115, Issue 36, p. 8978
Many Gram-positive pathogenic bacteria employ ribosomal protection proteins (RPPs) to confer resistance to clinically important antibiotics. In Bacillus... 
Linezolid | Pathogens | tRNA | Ribosomes | Chloramphenicol | Erythromycin | Electron microscopy | Chloromycetin | Studies | Proteins | Tiamulin | Virginiamycin | Antibiotics | Lincomycin | Antibiotic resistance | Bacteria | Peptidyltransferase | Adenosine triphosphatase | Binding sites
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2016, Volume 6, Issue 1, p. 39004
The increasing appearance of pathogenic bacteria with antibiotic resistance is a global threat. Consequently, clinically available potent antibiotics that are... 
SYSTEM | SITE | ANTIBIOTICS | INHIBITION | SPECIFICITY | TIAMULIN | MULTIDISCIPLINARY SCIENCES | RESISTANCE | STAPHYLOCOCCUS-AUREUS | DERIVATIVES | RIBOSOME | Pathogens | Antibiotics | Multidrug resistance | Antibiotic resistance | Ribosomes | Protein biosynthesis | Drug development | Crystal structure
Journal Article
Journal of Animal Science, ISSN 0021-8812, 05/2019, Volume 97, Issue 5, pp. 2035 - 2052
Antibiotic use has been limited in U.S. swine production. Therefore, the objective was to determine whether supplementing l-glutamine at cost-effective levels... 
Productivity | Aggressive behavior | Weaning | Health | Huddling | Dietary supplements | Summer | Tumor necrosis factor-α | Tiamulin | Hogs | Diet | Antibiotics | Swine | Chlortetracycline | Livestock | Supplementation | Transport | Glutamine
Journal Article
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, ISSN 0066-4804, 09/2019, Volume 63, Issue 9
The tva(A) gene suspected to confer resistance to pleuromutilins in Brachyspira hyodysenteriae was tested for functionality in Escherichia coli AG100A and... 
ANTIMICROBIAL SUSCEPTIBILITY | swine dysentery | MACROLIDE | MICROBIOLOGY | virginiamycin M1 | tiamulin | antibiotic resistance | valnemulin | pristinamycin IIA | RESISTANCE | 50S RIBOSOMAL-SUBUNIT | PHARMACOLOGY & PHARMACY | ABC-F protein | MUTATIONS | gene expression
Journal Article
Journal of Animal Science, ISSN 0021-8812, 04/2018, Volume 96, pp. 111 - 112
Benzoic acid supplement (BA) was evaluated as an alternative to anti-microbial growth promoter in weaned pigs. A total of 96 piglets (6.2±.3 kg BW) were weaned... 
Benzoic acid | Soybeans | Weaning | Corn | Diarrhea | Antiinfectives and antibacterials | Tiamulin | Hogs | Microorganisms | Antibiotics | Diet | Acids | Chlortetracycline | Physical growth | Feeds
Journal Article
Journal of Animal Science, ISSN 0021-8812, 04/2018, Volume 96, pp. 152 - 153
The objectives were to develop guidelines for studies evaluating alternatives to sub-therapeutic antibiotic growth promoters (AGP) and to evaluate the effects... 
Additives | Potatoes | Weaning | Starch | Septicemia | Growth promoters | Group size | Diarrhea | Data processing | Zinc | Tiamulin | Hogs | Microorganisms | Antibiotics | Diet | Acids | Chlortetracycline | Zinc oxide | Feeds | Pens
Journal Article
Applied and Environmental Microbiology, ISSN 0099-2240, 11/2018, Volume 84, Issue 21
One hundred seventy-eight mycoplasma strains isolated from South African poultry flocks between 2003 and 2015 were identified by full-genome sequencing and... 
rRNA 16S | Microbiology | Poultry | Multidrug resistance | rRNA 23S | Genomes | Phylogeny | Ribonucleic acid--RNA | Enrofloxacin | Gene sequencing | Oxytetracycline | Proteins | Tiamulin | Multidrug resistant organisms | Sensitivity | Chickens | Point mutation | Minimum inhibitory concentration | Chlortetracycline | Tylosin | Mutation | Species
Journal Article
Research in Veterinary Science, ISSN 0034-5288, 10/2014, Volume 97, Issue 2, pp. 341 - 347
With the emergence of “ ” associated with swine dysentery in North America, identification of effective treatments and interventions is a pressing need.... 
Brachyspira | Brachyspira hyodysenteriae | Swine dysentery | Tiamulin | Brachyspira hampsonii
Journal Article
Journal of Animal Science, ISSN 0021-8812, 07/2019, Volume 97, pp. 64 - 64
Foodborne pathogens are a significant cause of disease in humans, and meat-producing animals are reservoirs for a variety of these pathogens. Consumption of... 
Shedding | Weaning | Food contamination | Animal diseases | Infections | Lactobacillus acidophilus | Meat | Food chains | E coli | Swine | Feces | Supplementation | Meat products | Lysozyme | Campylobacter | Pathogens | Animal wastes | Dietary supplements | Fermentation | Tiamulin | Hogs | Diet | Water pollution | Livestock | Sulfate | Colonization | Meat quality
Journal Article
Toxicology in Vitro, ISSN 0887-2333, 10/2018, Volume 52, p. 314
Salinomycin (SAL) is a polyether antibiotic, which is commonly used as a coccidiostat and has recently shown to exhibit anticancer activity. The toxic action... 
Cell culture | Biotechnology | Animal models | Toxicity | Cytotoxicity | Cultures | Hepatoma | Myoblasts | Anticancer properties | Membrane proteins | Proteins | Tiamulin | Mitochondria | Salinomycin | Antibiotics | Metabolites | Hepatocytes | Rodents | Biotransformation | Antitumor activity | Prednisolone
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 04/2018, Volume 62, Issue 4
Journal Article
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