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Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2008, Volume 359, Issue 12, pp. 1238 - 1251
In this large clinical trial, aspirin plus extended-release dipyridamole was found to have an efficacy similar to that of clopidogrel in the prevention of... 
ACTIVE CONTROLLED-TRIALS | HIGH-RISK PATIENTS | TICLOPIDINE | TRANSIENT ISCHEMIC ATTACK | DOUBLE-BLIND | PREVENTION | RANDOMIZED CONTROLLED-TRIAL | ARTERIAL ORIGIN ESPRIT | CEREBRAL-ISCHEMIA | UMCG Approved | NON-INFERIORITY TRIALS | ISSUES | MEDICINE, GENERAL & INTERNAL | PLACEBO | DESIGN | WARFARIN | REGIMENS | Myocardial Infarction - epidemiology | Benzoates - therapeutic use | Ticlopidine - therapeutic use | Humans | Middle Aged | Male | Risk | Secondary Prevention | Aspirin - administration & dosage | Vascular Diseases - mortality | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Aspirin - adverse effects | Platelet Aggregation Inhibitors - administration & dosage | Ticlopidine - adverse effects | Dipyridamole - adverse effects | Female | Stroke - epidemiology | Drug Therapy, Combination | Platelet Aggregation Inhibitors - therapeutic use | Dipyridamole - therapeutic use | Benzimidazoles - therapeutic use | Platelet Aggregation Inhibitors - adverse effects | Brain Ischemia - epidemiology | Stroke - prevention & control | Double-Blind Method | Kaplan-Meier Estimate | Proportional Hazards Models | Brain Ischemia - prevention & control | Factor Analysis, Statistical | Stroke - drug therapy | Ticlopidine - analogs & derivatives | Aged | Hemorrhage - chemically induced | Delayed-Action Preparations | Stroke (Disease) | Aspirin | Usage | Care and treatment | Dipyridamole | Clopidogrel | Health aspects | Stroke | Index Medicus | Abridged Index Medicus | Recurrence | Brain Ischemia | Benzimidazoles | Follow-Up Studies | Neurons and Cognition | Cognition | Hemorrhage | Drug Delivery Systems | Life Sciences | Angiotensin II Type 1 Receptor Blockers | Angiotensin-Converting Enzyme Inhibitors | Vascular Diseases | Mental Status Schedule | Retrospective Studies | Severity of Illness Index | Disability Evaluation | Benzoates | Drug Administration Schedule | International Cooperation | Ticlopidine | Myocardial Infarction | Platelet Aggregation Inhibitors | Santé publique et épidémiologie | Original | Dipyridamole/adverse effects/therapeutic use | Angiotensin-Converting Enzyme Inhibitors/therapeutic use | Recurrence/prevention & control | Benzoates/therapeutic use | Brain Ischemia/epidemiology/prevention & control | MEDICIN OCH HÄLSOVETENSKAP | Platelet Aggregation Inhibitors/administration & dosage/adverse | Combination | MEDICAL AND HEALTH SCIENCES | Aspirin/administration & dosage/adverse effects | Myocardial Infarction/epidemiology | Factor Analysis | Benzimidazoles/therapeutic use | Drug Therapy | Ticlopidine/adverse effects/analogs & derivatives/therapeutic use | effects/therapeutic use | Vascular Diseases/mortality | Hemorrhage/chemically induced | Stroke/drug therapy/epidemiology/prevention & control | Statistical | Kaplan-Meiers Estimate
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2009, Volume 360, Issue 4, pp. 354 - 362
The antiplatelet drug clopidogrel requires activation by cytochrome P-450 (CYP) enzymes. This study shows that CYP polymorphisms that reduce clopidogrel... 
VARIABILITY | MEDICINE, GENERAL & INTERNAL | PERCUTANEOUS CORONARY INTERVENTION | PHARMACOKINETICS | STENT THROMBOSIS | INCREASED RISK | PLATELET INHIBITION | PRASUGREL | PHARMACODYNAMICS | INDIVIDUAL RESPONSIVENESS | ATHEROTHROMBOTIC EVENTS | Ticlopidine - pharmacology | Ticlopidine - therapeutic use | Area Under Curve | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Male | Cardiovascular Diseases - genetics | Angioplasty, Balloon, Coronary | Ticlopidine - adverse effects | Ticlopidine - metabolism | Cardiovascular Diseases - epidemiology | Platelet Aggregation Inhibitors - pharmacology | Adult | Female | Platelet Aggregation - drug effects | Platelet Aggregation Inhibitors - metabolism | Platelet Aggregation Inhibitors - therapeutic use | Stents | Platelet Aggregation Inhibitors - adverse effects | Genotype | Thrombosis - epidemiology | Combined Modality Therapy | Ticlopidine - analogs & derivatives | Polymorphism, Genetic | Randomized Controlled Trials as Topic | Cytochrome P-450 CYP2C19 | Acute Coronary Syndrome - therapy | Heterozygote | Thrombosis - genetics | Mutation | Usage | Genetic variation | Cytochrome P-450 | Physiological aspects | Causes of | Clopidogrel | Cardiovascular diseases | Health aspects | Risk factors | Studies | Cardiovascular disease | Heart attacks | Drug therapy | Index Medicus | Abridged Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2009, Volume 360, Issue 20, pp. 2066 - 2078
A randomized trial enrolled 7554 patients with atrial fibrillation who were at increased risk of stroke but not candidates for vitamin K antagonists.... 
STROKE | CONTROLLED-TRIAL | MEDICINE, GENERAL & INTERNAL | ORAL ANTICOAGULATION | WARFARIN | ANTITHROMBOTIC THERAPY | THROMBOGENESIS | VASCULAR EVENTS | RISK | ACUTE CORONARY SYNDROMES | PLATELET ACTIVATION | Myocardial Infarction - epidemiology | Follow-Up Studies | Ticlopidine - therapeutic use | Humans | Middle Aged | Male | Risk | Incidence | Vascular Diseases - mortality | Vitamin K - antagonists & inhibitors | Aspirin - adverse effects | Ticlopidine - adverse effects | Female | Stroke - epidemiology | Aspirin - therapeutic use | Drug Therapy, Combination | Platelet Aggregation Inhibitors - therapeutic use | Embolism - epidemiology | Platelet Aggregation Inhibitors - adverse effects | Stroke - prevention & control | Double-Blind Method | Hemorrhage - epidemiology | Atrial Fibrillation - drug therapy | Atrial Fibrillation - complications | Ticlopidine - analogs & derivatives | Aged | Myocardial Infarction - prevention & control | Hemorrhage - chemically induced | Evaluation | Complications and side effects | Aspirin | Atrial fibrillation | Clopidogrel | Drug therapy | Hemorrhage | Risk factors | Cardiac arrhythmia | Medical research | Stroke | Mortality | Data collection | Cardiovascular disease | Acute coronary syndromes | Index Medicus | Abridged Index Medicus | Bioengineering | Life Sciences | Vascular Diseases | Computer Science | Atrial Fibrillation | Vitamin K | Embolism | Ticlopidine | Signal and Image processing | Myocardial Infarction | Platelet Aggregation Inhibitors | Engineering Sciences | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 01/2008, Volume 51, Issue 3, pp. 256 - 260
Journal Article
JAMA, ISSN 0098-7484, 10/2010, Volume 304, Issue 16, pp. 1821 - 1830
Journal Article
Journal Article