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Oncogene, ISSN 0950-9232, 05/2013, Volume 32, Issue 18, pp. 2282 - 2291
Cystic fibrosis (CF) transmembrane conductance regulator (CFTR) is expressed in the epithelial cells of a wide range of organs/tissues from which most cancers... 
CFTR | miR-193b | uPA | MUC4 EXPRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PANCREATIC ADENOCARCINOMA | CELL MIGRATION | MESENCHYMAL TRANSITION | MIR-200 FAMILY | CELL BIOLOGY | TRANSMEMBRANE CONDUCTANCE REGULATOR | BREAST-CANCER | HEPATOCELLULAR-CARCINOMA | ONCOLOGY | GENETICS & HEREDITY | NF-KAPPA-B | CYSTIC-FIBROSIS GENE | Prostatic Neoplasms - metabolism | Receptors, Urokinase Plasminogen Activator - immunology | Humans | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | Male | Cell Movement - genetics | Gene Knockdown Techniques | Prostatic Neoplasms - genetics | Base Sequence | Female | Urokinase-Type Plasminogen Activator - immunology | Prostatic Neoplasms - pathology | Down-Regulation | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Urokinase-Type Plasminogen Activator - genetics | Receptors, Urokinase Plasminogen Activator - metabolism | Xenograft Model Antitumor Assays | Animals | Urokinase-Type Plasminogen Activator - metabolism | Mice, Nude | Cell Line, Tumor | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Mice | MicroRNAs - genetics | Receptors, Urokinase Plasminogen Activator - genetics | Urokinase | Tissue plasminogen activator | Physiological aspects | Development and progression | Tumor suppressor genes | Genetic aspects | Research | Prostate cancer | Cystic fibrosis | Membranes | Tumors
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2005, Volume 280, Issue 43, pp. 36529 - 36540
The invasive ability of tumor cells plays a key role in prostate cancer metastasis and is a major cause of treatment failure. Urokinase plasminogen... 
MIGRATION | VITRO | GROWTH-FACTOR-RECEPTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODEL | GENE-EXPRESSION | DOWN-REGULATION | UPA PROMOTER | TUMOR-GROWTH | ANTISENSE OLIGONUCLEOTIDES | CATHEPSIN-B | Laminin - pharmacology | Neoplasm Transplantation | Prostatic Neoplasms - metabolism | Cell Proliferation | Humans | Extracellular Matrix - metabolism | Collagen - chemistry | Immunoblotting | Male | Proteoglycans - chemistry | Neoplasm Metastasis | Transfection | RNA Interference | Time Factors | Collagen - pharmacology | Prostatic Neoplasms - pathology | Signal Transduction | Cell Survival | Neoplasm Invasiveness | Electrophoresis, Polyacrylamide Gel | Gene Silencing | Tetrazolium Salts - pharmacology | Urokinase-Type Plasminogen Activator - genetics | Reverse Transcriptase Polymerase Chain Reaction | Plasmids - metabolism | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Proteoglycans - pharmacology | Urokinase-Type Plasminogen Activator - metabolism | Mice, Nude | Cell Line, Tumor | Laminin - chemistry | Mice | Thiazoles - pharmacology | Neoplasms - pathology | Drug Combinations | Microscopy, Fluorescence | Apoptosis | Mitogen-Activated Protein Kinase 1 - metabolism | RNA, Small Interfering - metabolism | RNAi | uPAR (uPA receptor) | shRNA (small hairpin RNA) | uPA (urokinaseplasminogen activator) | survival | siRNA (small interfering RNA) | prostate cancer | invasion | uPA and uPAR | ANOVA (analysis of variance) | RNAi (RNA interference) | RT (reverse transcription) | TPBS (tween-20 (0.1%) phospate buffered saline) | BSA (bovine serum albumin)
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 03/2017, Volume 45, Issue 6, pp. 805 - 815
Glutamate phase shifts the circadian clock in the mammalian suprachiasmatic nucleus ( SCN ) by activating NMDA receptors. Tissue‐type plasminogen activator (... 
urokinase‐type plasminogen activator | circadian rhythms | suprachiasmatic nucleus | tissue‐type plasminogen activator | urokinase-type plasminogen activator | tissue-type plasminogen activator | NEURONAL MIGRATION | CELL-ADHESION MOLECULE | NEUROTROPHIC FACTOR | RECEPTOR | NEUROSCIENCES | IN-VITRO | EXTRACELLULAR-MATRIX | BIOLOGICAL CLOCK | BRAIN | GENE-FUNCTION | Brain-Derived Neurotrophic Factor - genetics | Suprachiasmatic Nucleus - drug effects | Tissue Plasminogen Activator - metabolism | Mice, Inbred C57BL | Plasminogen Inactivators - pharmacology | Male | Tissue Plasminogen Activator - genetics | Suprachiasmatic Nucleus - physiology | Animals | Urokinase-Type Plasminogen Activator - metabolism | Proteolysis | Circadian Clocks | Female | Suprachiasmatic Nucleus - metabolism | Brain-Derived Neurotrophic Factor - metabolism | Mice | Urokinase | Glutamate | Tissue plasminogen activator | Laws, regulations and rules | Suprachiasmatic nucleus | Glutamic acid | Brain | Night | Glutamic acid receptors (ionotropic) | Brain slice preparation | Nuclei | Plasmin | t-Plasminogen activator | Receptors | Casein | Rodents | Entrainment | Inhibition | Biological clocks | Circadian rhythms | Phase transformations | Phase shift | Polyamide-imides | N-Methyl-D-aspartic acid receptors | Circadian rhythm | Mammals | U-Plasminogen activator | Brain-derived neurotrophic factor | Inhibitors | Plasminogen activator inhibitors | TrkB receptors | Glutamatergic transmission | Gates
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 09/2014, Volume 73, Issue 9, pp. 1700 - 1709
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2013, Volume 288, Issue 47, pp. 34009 - 34018
In addition to functioning as an activator of fibrinolysis, tissue-type plasminogen activator (tPA) interacts with neurons and regulates multiple aspects of... 
RECEPTOR-RELATED PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | Protease Inhibitor | BLOOD-BRAIN-BARRIER | NERVE GROWTH-FACTOR | ALPHA-2-MACROGLOBULIN RECEPTOR | NEURITE OUTGROWTH | MEDIATED ACTIVATION | Cell Signaling | Tissue-type Plasminogen Activator (tPA) | MOLECULAR DISSECTION | LONG-TERM POTENTIATION | ERK | Lipoprotein-like Receptor (LRP) | METHYL-D-ASPARTATE | CALCIUM RESPONSES | Disks Large Homolog 4 Protein | Guanylate Kinases - genetics | MAP Kinase Signaling System - physiology | Tissue Plasminogen Activator - metabolism | Humans | Myelin-Associated Glycoprotein - genetics | Myelin-Associated Glycoprotein - metabolism | alpha-Macroglobulins - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Receptors, Nerve Growth Factor - metabolism | Low Density Lipoprotein Receptor-Related Protein-1 - genetics | Tissue Plasminogen Activator - genetics | PC12 Cells | Mitogen-Activated Protein Kinase 1 - genetics | Tumor Suppressor Proteins - genetics | Membrane Proteins - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Lactoferrin - metabolism | Receptors, LDL - genetics | Tumor Suppressor Proteins - metabolism | Mitogen-Activated Protein Kinase 3 - genetics | Membrane Proteins - genetics | Low Density Lipoprotein Receptor-Related Protein-1 - metabolism | Rats | Receptors, LDL - metabolism | Nerve Tissue Proteins - genetics | Receptors, Nerve Growth Factor - genetics | Lactoferrin - genetics | Nerve Tissue Proteins - metabolism | alpha-Macroglobulins - metabolism | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Guanylate Kinases - metabolism | Mice | Mitogen-Activated Protein Kinase 1 - metabolism | Signal Transduction
Journal Article
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