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1. Full Text RNA Interference-directed Knockdown of Urokinase Plasminogen Activator and Urokinase Plasminogen Activator Receptor Inhibits Prostate Cancer Cell Invasion, Survival, and Tumorigenicity in Vivo
by Sai MuraliKrishna Pulukuri and Christopher S. Gondi and Sajani S. Lakka and Aman Jutla and Norman Estes and Meena Gujrati and Jasti S. Rao
The Journal of biological chemistry, ISSN 0021-9258, 10/2005, Volume 280, Issue 43, pp. 36529 - 36540
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Laminin - pharmacology | Neoplasm Transplantation | Prostatic Neoplasms - metabolism | Cell Proliferation | Humans | Extracellular Matrix - metabolism | Collagen - chemistry | Immunoblotting | Male | Proteoglycans - chemistry | Neoplasm Metastasis | Transfection | RNA Interference | Time Factors | Collagen - pharmacology | Prostatic Neoplasms - pathology | Signal Transduction | Cell Survival | Neoplasm Invasiveness | Electrophoresis, Polyacrylamide Gel | Gene Silencing | Tetrazolium Salts - pharmacology | Urokinase-Type Plasminogen Activator - genetics | Reverse Transcriptase Polymerase Chain Reaction | Plasmids - metabolism | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Proteoglycans - pharmacology | Urokinase-Type Plasminogen Activator - metabolism | Mice, Nude | Cell Line, Tumor | Laminin - chemistry | Mice | Thiazoles - pharmacology | Neoplasms - pathology | Drug Combinations | Microscopy, Fluorescence | Apoptosis | Mitogen-Activated Protein Kinase 1 - metabolism | RNA, Small Interfering - metabolism | Index Medicus | RNAi | uPAR (uPA receptor) | shRNA (small hairpin RNA) | uPA (urokinaseplasminogen activator) | survival | siRNA (small interfering RNA) | prostate cancer | invasion | uPA and uPAR | ANOVA (analysis of variance) | RNAi (RNA interference) | RT (reverse transcription) | TPBS (tween-20 (0.1%) phospate buffered saline) | BSA (bovine serum albumin)
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2. Full Text Plasminogen Activator Inhibitor Type‐1 as a Regulator of Fibrosis
by Rabieian, Reyhaneh and Boshtam, Maryam and Zareei, Mahshid and Kouhpayeh, Shirin and Masoudifar, Aria and Mirzaei, Hamed
Journal of cellular biochemistry, ISSN 0730-2312, 01/2018, Volume 119, Issue 1, pp. 17 - 27
UROKINASE PLASMINOGEN ACTIVATOR (uPA) | FIBRINOLYSIS | TRANSFORMING GROWTH FACTOR‐β (TGF‐β) | PLASMINOGEN ACTIVATOR INHIBITOR‐1 (PAI‐1) | TISSUE PLASMINOGEN ACTIVATOR (tPA) | TRANSFORMING GROWTH FACTOR-β (TGF-β) | PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Disease - etiology | Fibrosis - genetics | Receptor Cross-Talk | Plasminogen Activator Inhibitor 1 - metabolism | Fibrosis - etiology | Humans | Gene Expression Regulation | Plasminogen Activator Inhibitor 1 - genetics | Plasminogen Activator Inhibitor 1 - physiology | Gene expression | Development and progression | Fibrosis | Smad protein | Pathogenesis | Transforming growth factor-b | Activation | t-Plasminogen activator | Degradation | Urokinase | Pathways | Etiology | Proteolysis | Extracellular matrix | Growth factors | Deposition | Injuries | Hypertension | Wound healing | Cytokines | Medical treatment | Diabetes mellitus | Polyamide-imides | Inflammation | U-Plasminogen activator | Inhibitors | Plasminogen activator inhibitors | Index Medicus
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3. Full Text Plasminogen Activator Inhibitor-1 Reduces Tissue-Type Plasminogen Activator–Dependent Fibrinolysis and Intrahepatic Hemorrhage in Experimental Acetaminophen Overdose
by Pant, Asmita and Kopec, Anna K and Baker, Kevin S and Cline-Fedewa, Holly and Lawrence, Daniel A and Luyendyk, James P
The American journal of pathology, ISSN 0002-9440, 05/2018, Volume 188, Issue 5, pp. 1204 - 1212
Life Sciences & Biomedicine | Pathology | Science & Technology | Drug Overdose - metabolism | Fibrinolysis - drug effects | Hemorrhage - genetics | Liver Diseases - genetics | Drug Overdose - genetics | Tissue Plasminogen Activator - metabolism | Hemorrhage - complications | Hemorrhage - metabolism | Tissue Plasminogen Activator - genetics | Mice, Knockout | Animals | Plasminogen Activator Inhibitor 1 - metabolism | Acetaminophen - poisoning | Liver Diseases - complications | Drug Overdose - complications | Mice | Plasminogen Activator Inhibitor 1 - genetics | Liver Diseases - metabolism | Index Medicus | Abridged Index Medicus
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4. Full Text CFTR suppresses tumor progression through miR-193b targeting urokinase plasminogen activator (uPA) in prostate cancer
by Xie, C and Jiang, X.H and Zhang, J.T and Sun, T.T and Dong, J.D and Sanders, A.J and Diao, R.Y and Wang, Y and Fok, K.L and Tsang, L.L and Yu, M.K and Zhang, X.H and Chung, Y.W and Ye, L and Zhao, M.Y and Guo, J.H and Xiao, Z.J and Lan, H.Y and Ng, C.F and Lau, K.M and Cai, Z.M and Jiang, W.G and Chan, H.C
Oncogene, ISSN 0950-9232, 05/2013, Volume 32, Issue 18, pp. 2282 - 2291
CFTR | miR-193b | uPA | Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Prostatic Neoplasms - metabolism | Receptors, Urokinase Plasminogen Activator - immunology | Humans | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | Male | Cell Movement - genetics | Gene Knockdown Techniques | Prostatic Neoplasms - genetics | Base Sequence | Female | Urokinase-Type Plasminogen Activator - immunology | Prostatic Neoplasms - pathology | Down-Regulation | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Urokinase-Type Plasminogen Activator - genetics | Receptors, Urokinase Plasminogen Activator - metabolism | Xenograft Model Antitumor Assays | Animals | Urokinase-Type Plasminogen Activator - metabolism | Mice, Nude | Cell Line, Tumor | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Mice | MicroRNAs - genetics | Receptors, Urokinase Plasminogen Activator - genetics | Urokinase | Tissue plasminogen activator | Physiological aspects | Development and progression | Tumor suppressor genes | Genetic aspects | Research | Prostate cancer | Cystic fibrosis | Membranes | Tumors | Index Medicus
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5. Full Text Human tissue-type plasminogen activator
by Kruithof, Egbert K. O and Dunoyer-Geindre, Sylvie
Thrombosis and haemostasis, ISSN 0340-6245, 2014, Volume 111, Issue 8, pp. 243 - 254
Review Article | Nervous system | Plasminogen activators | Gene regulation | Endothelial cells | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Hematologic and hematopoietic diseases | Biological and medical sciences | Blood coagulation. Blood cells | Molecular and cellular biology | Medical sciences | Platelet diseases and coagulopathies | Gene Expression Regulation, Enzymologic - drug effects | Promoter Regions, Genetic | Transcription, Genetic - drug effects | Genetic Predisposition to Disease | Tissue Plasminogen Activator - metabolism | Humans | Risk Factors | Molecular Sequence Data | Tissue Plasminogen Activator - chemistry | Cardiovascular Diseases - enzymology | Tissue Plasminogen Activator - genetics | Cardiovascular Diseases - genetics | Signal Transduction - drug effects | Base Sequence | Cardiovascular Diseases - epidemiology | Epigenesis, Genetic - drug effects | Protein Processing, Post-Translational
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6. Full Text Impacts of aging and amyloid-β deposition on plasminogen activators and plasminogen activator inhibitor-1 in the Tg2576 mouse model of Alzheimers disease
by Bi Oh, Shin and Suh, Nayoung and Kim, Inki and Lee, Joo-Yong
Brain research, ISSN 0006-8993, 02/2015, Volume 1597, pp. 159 - 167
Amyloid degrading enzymes | Amyloid pathogenesis | Amyloid plaques | Plasmin | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neurons - pathology | Tissue Plasminogen Activator - metabolism | Neuroglia - pathology | Humans | Cerebral Cortex - pathology | Cerebral Cortex - metabolism | Alzheimer Disease - pathology | Amyloid beta-Peptides - metabolism | Amyloid beta-Protein Precursor - metabolism | Female | Neurons - metabolism | Fibrinolysin - metabolism | Disease Models, Animal | Plaque, Amyloid - pathology | Mice, Inbred C57BL | Mice, Transgenic | Hippocampus - pathology | Hippocampus - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Urokinase-Type Plasminogen Activator - metabolism | Alzheimer Disease - metabolism | Neuroglia - metabolism | Plaque, Amyloid - metabolism | Serpin E2 - metabolism | Aging - metabolism | Index Medicus
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7. Full Text Urokinase‐type plasminogen activator modulates mammalian circadian clock phase regulation in tissue‐type plasminogen activator knockout mice
by Cooper, Joanna M and Rastogi, Ashutosh and Krizo, Jessica A and Mintz, Eric M and Prosser, Rebecca A and Silver, Rae
The European journal of neuroscience, ISSN 0953-816X, 03/2017, Volume 45, Issue 6, pp. 805 - 815
urokinase‐type plasminogen activator | circadian rhythms | suprachiasmatic nucleus | tissue‐type plasminogen activator | urokinase-type plasminogen activator | tissue-type plasminogen activator | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Brain-Derived Neurotrophic Factor - genetics | Suprachiasmatic Nucleus - drug effects | Tissue Plasminogen Activator - metabolism | Mice, Inbred C57BL | Plasminogen Inactivators - pharmacology | Male | Tissue Plasminogen Activator - genetics | Suprachiasmatic Nucleus - physiology | Animals | Urokinase-Type Plasminogen Activator - metabolism | Proteolysis | Circadian Clocks | Female | Suprachiasmatic Nucleus - metabolism | Brain-Derived Neurotrophic Factor - metabolism | Mice | Urokinase | Glutamate | Tissue plasminogen activator | Laws, regulations and rules | Suprachiasmatic nucleus | Glutamic acid | Brain | Night | Glutamic acid receptors (ionotropic) | Brain slice preparation | Nuclei | Phase transitions | Plasmin | t-Plasminogen activator | Receptors | Casein | Rodents | Entrainment | Inhibition | Biological clocks | Circadian rhythms | Phase shift | Polyamide-imides | N-Methyl-D-aspartic acid receptors | Circadian rhythm | Mammals | U-Plasminogen activator | Brain-derived neurotrophic factor | Inhibitors | Plasminogen activator inhibitors | TrkB receptors | Glutamatergic transmission | Gates | Index Medicus
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