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Journal Article
Osteoarthritis and Cartilage, ISSN 1063-4584, 2013, Volume 22, Issue 1, pp. 133 - 144
Summary Objective Interleukin-1β (IL-1β) is involved in the up-regulation of matrix metalloproteinases (MMPs) leading to cartilage degradation. Cannabinoids... 
Rheumatology | Matrix metalloproteinases (MMPs) | Interleukin 1 (IL-1) | Cannabinoid | Tissue inhibitors of matrix metalloproteinases (TIMP) | Cartilage degradation | Chondrocytes | INTERFERON-BETA TREATMENT | RHEUMATOID-ARTHRITIS | COLLAGEN-INDUCED ARTHRITIS | ACTIVATED RECEPTOR-ALPHA | HUMAN ARTICULAR CHONDROCYTES | RHEUMATOLOGY | CYTOKINE PRODUCTION | MESSENGER-RNA | HUMAN OSTEOARTHRITIC CARTILAGE | Tissue inhibitors of matrix | GENE-EXPRESSION | PPAR-GAMMA | ORTHOPEDICS | metalloproteinases (TIMP) | Interleukin-1beta - pharmacology | Tissue Inhibitor of Metalloproteinase-1 - biosynthesis | Humans | Hexuronic Acids | Matrix Metalloproteinase 13 - biosynthesis | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Receptors, Cannabinoid - metabolism | Chondrocytes - drug effects | Glucuronic Acid | Cartilage, Articular - metabolism | Tissue Inhibitor of Metalloproteinase-2 - biosynthesis | Cell Death - drug effects | Chondrocytes - metabolism | Tissue Inhibitor of Metalloproteinases - biosynthesis | Interleukin-1beta - antagonists & inhibitors | Matrix Metalloproteinases - biosynthesis | Drug Evaluation, Preclinical - methods | Matrix Metalloproteinase 13 - genetics | Cells, Cultured | Morpholines - pharmacology | Alginates | Matrix Metalloproteinase 3 - biosynthesis | Naphthalenes - pharmacology | Gene Expression Regulation - drug effects | Cartilage, Articular - pathology | Osteoarthritis, Knee - pathology | Benzoxazines - pharmacology | Matrix Metalloproteinase 3 - genetics | Osteoarthritis, Knee - metabolism
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