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Journal of Neurochemistry, ISSN 0022-3042, 04/2010, Volume 113, Issue 2, pp. 530 - 542
Adenosine produces cardiovascular depressor effects in various brain regions. However, the cellular mechanisms underlying these effects remain unclear. The... 
Adenosine receptors | G proteins | Hypothalamus | Sympathetic nervous system | Synaptic transmission | SUPRAOPTIC NUCLEUS | PRESYNAPTIC INHIBITION | SPONTANEOUSLY HYPERTENSIVE-RATS | sympathetic nervous system | SENSITIVE K+ CHANNELS | RECEPTOR AGONISTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SPINAL-CORD | K-ATP | NEUROSCIENCES | SIGNALING PATHWAY | adenosine receptors | ENDOGENOUS ADENOSINE | synaptic transmission | CENTRAL-NERVOUS-SYSTEM | hypothalamus | SYNAPTIC GABA RELEASE | Analgesics - pharmacology | Tolbutamide - pharmacology | KATP Channels - physiology | Male | Xanthines - pharmacology | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Dose-Response Relationship, Drug | Paraventricular Hypothalamic Nucleus - cytology | Glyburide - pharmacology | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Tetrodotoxin - pharmacology | Neurons - drug effects | Action Potentials - drug effects | Potassium Channel Blockers - pharmacology | Guanosine Diphosphate - pharmacology | Membrane Potentials - drug effects | Triazines - pharmacology | Rats | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Adenosine - pharmacology | Bicuculline - pharmacology | Thionucleotides - pharmacology | Membrane Potentials - physiology | Rats, Sprague-Dawley | Receptor, Adenosine A1 - metabolism | GABA Antagonists - pharmacology | Triazoles - pharmacology | Animals | Guanosine Diphosphate - analogs & derivatives | In Vitro Techniques | Cell research | Adenosine | Neurons | Tolbutamide | GABA | Glibenclamide | Cytochemistry | Membrane proteins | Cardiovascular disease | Potassium | Adenosine triphosphatase
Journal Article
Journal Article
Journal of Neurophysiology, ISSN 0022-3077, 12/2011, Volume 106, Issue 6, pp. 2865 - 2875
Journal Article
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 11/2007, Volume 35, Issue 11, pp. 2119 - 2126
Predicting drug-drug interactions requires an assessment of the drug concentration available to the enzyme active site, both in vivo, and within an in vitro... 
Tolbutamide - pharmacology | Cytochrome P-450 Enzyme Inhibitors | Cytochrome P-450 CYP3A | Microsomes, Liver - metabolism | Cytochrome P-450 Enzyme System - metabolism | Dextromethorphan - metabolism | Male | Fluconazole - metabolism | Quinine - pharmacology | Microsomes, Liver - enzymology | Tolbutamide - metabolism | Fluoxetine - pharmacology | Dextromethorphan - pharmacology | Enzyme Inhibitors - metabolism | Enzyme Inhibitors - pharmacology | Fluvoxamine - pharmacokinetics | Ketoconazole - pharmacokinetics | Rats | Rats, Sprague-Dawley | Catalysis - drug effects | Miconazole - pharmacokinetics | Miconazole - pharmacology | Fluoxetine - metabolism | Cytochrome P-450 CYP2D6 - metabolism | Kinetics | Midazolam - pharmacology | Hepatocytes - enzymology | Cytochrome P-450 CYP2D6 Inhibitors | Quinine - pharmacokinetics | Fluconazole - pharmacology | Tolbutamide - pharmacokinetics | Fluoxetine - pharmacokinetics | Ketoconazole - metabolism | Hepatocytes - metabolism | Ketoconazole - pharmacology | Hepatocytes - cytology | Enzyme Inhibitors - pharmacokinetics | Phenytoin - pharmacology | Dextromethorphan - pharmacokinetics | Phenytoin - metabolism | Quinine - metabolism | Fluvoxamine - metabolism | Cells, Cultured | Midazolam - pharmacokinetics | Fluvoxamine - pharmacology | Miconazole - metabolism | Fluconazole - pharmacokinetics | Animals | Midazolam - metabolism | Phenytoin - pharmacokinetics
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Pharmacology, Biochemistry and Behavior, ISSN 0091-3057, 2006, Volume 83, Issue 3, pp. 420 - 427
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Journal Article
Molecules, ISSN 1420-3049, 11/2017, Volume 22, Issue 11, p. 1994
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 11/2009, Volume 30, Issue 10, pp. 1849 - 1859
Journal Article
Science, ISSN 0036-8075, 7/2009, Volume 325, Issue 5940, pp. 607 - 610
Epac2, a guanine nucleotide exchange factor for the small guanosine triphosphatase Rap1, is activated by adenosine 3′,5′-monophosphate. Fluorescence resonance... 
COS cells | Blood glucose | Medical research | Biomedical technology | Reports | Hypoglycemic agents | Diabetes | Sensors | Insulin | Insulin secretion | Vehicles | B-CELLS | ACTIVATION | STIMULATION | EXOCYTOSIS | K-ATP CHANNELS | GRANULE | MULTIDISCIPLINARY SCIENCES | INSULIN-SECRETION | PANCREATIC BETA-CELLS | RECEPTOR | MICE | Tolbutamide - pharmacology | Hypoglycemic Agents - metabolism | Cercopithecus aethiops | Insulin - blood | Sulfonylurea Compounds - chemistry | Glucose - administration & dosage | Glyburide - pharmacology | Guanine Nucleotide Exchange Factors - metabolism | Islets of Langerhans - metabolism | Sulfonylurea Compounds - metabolism | Sulfonylurea Compounds - pharmacology | Fluorescence Resonance Energy Transfer | Cyclic AMP - metabolism | Insulin Secretion | Tolbutamide - metabolism | Cell Line | rap1 GTP-Binding Proteins - metabolism | Guanine Nucleotide Exchange Factors - genetics | Blood Glucose - analysis | 8-Bromo Cyclic Adenosine Monophosphate - pharmacology | Mice, Inbred C57BL | Hypoglycemic Agents - chemistry | Glyburide - metabolism | Hypoglycemic Agents - pharmacology | Carrier Proteins - genetics | Insulin - metabolism | Animals | Carrier Proteins - metabolism | Mice | COS Cells | Properties | Cyclic adenylic acid | Prescription drugs | Rodents | Pharmacology | Glucose | Metabolism
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