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Nature medicine, ISSN 1546-170X, 2017, Volume 23, Issue 2, pp. 174 - 184
...Author(s): David Furman (corresponding author) [1, 2]; Junlei Chang [3]; Lydia Lartigue [4]; Christopher R Bolen [5]; Francois Haddad [6]; Brice Gaudilliere [5... 
MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | INTERLEUKIN-18 LEVELS | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CARDIOVASCULAR-DISEASE | RECEPTOR | ESSENTIAL-HYPERTENSION | PROTEINS | T-CELLS | AGE | CELL BIOLOGY | Toll-Like Receptor 5 - genetics | Humans | Middle Aged | Oxidative Stress - immunology | Transcriptome | Immunoblotting | Male | Purinergic P1 Receptor Antagonists - pharmacology | Young Adult | Toll-Like Receptor 8 - immunology | Aging - immunology | Toll-Like Receptor 6 - immunology | Aging - genetics | Calcium-Binding Proteins - immunology | Interleukin-1beta - metabolism | Aged, 80 and over | Caffeine - pharmacology | Hypertension - genetics | Intracellular Signaling Peptides and Proteins - genetics | Interleukin 1 Receptor Antagonist Protein - immunology | Carotid Intima-Media Thickness | Mortality | Neutrophils - drug effects | Hypertension - immunology | Nucleotides - metabolism | Toll-Like Receptor 5 - immunology | Monocytes - drug effects | Regression Analysis | Phenotype | Mice | Calcium-Binding Proteins - genetics | Metabolomics | Pulse Wave Analysis | Neutrophil Activation - drug effects | Cytidine - pharmacology | Interleukin 1 Receptor Antagonist Protein - genetics | Intracellular Signaling Peptides and Proteins - immunology | Cytidine - analogs & derivatives | CARD Signaling Adaptor Proteins - genetics | Toll-Like Receptor 6 - genetics | Adult | Female | Blood Pressure - drug effects | Blood Platelets - drug effects | Macrophages - immunology | Cytokines - immunology | CARD Signaling Adaptor Proteins - immunology | Cell Line | Vascular Stiffness - genetics | Cytokines - metabolism | Oxidative Stress - genetics | Interleukin-1beta - immunology | Adenine - pharmacology | Inflammation - immunology | Inflammasomes - genetics | Vascular Stiffness - immunology | Animals | Inflammasomes - immunology | Toll-Like Receptor 8 - genetics | Inflammation - genetics | Aged | Platelet Activation - drug effects | Genetic aspects | Immune response | Gene expression | Health aspects | Aging | Inflammation | Immune system
Journal Article
Arthritis & rheumatology (Hoboken, N.J.), ISSN 2326-5191, 2015, Volume 67, Issue 12, pp. 3146 - 3157
Journal Article
BMC gastroenterology, ISSN 1471-230X, 2011, Volume 11, Issue 1, pp. 138 - 138
Background: Dysregulation of innate immune response by Toll-Like Receptors (TLRs) is a key feature in Ulcerative Colitis... 
MESSENGER-RNA EXPRESSION | POUCH MUCOSA | GASTROENTEROLOGY & HEPATOLOGY | TLR4 | INTESTINAL EPITHELIAL-CELLS | COLONIC-MUCOSA | BACTERIAL-DNA | BOWEL-DISEASE | Immunohistochemistry | Tumor Necrosis Factor-alpha - metabolism | Up-Regulation | Toll-Like Receptor 2 - genetics | Toll-Like Receptor 5 - genetics | Humans | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Toll-Like Receptor 9 - genetics | Male | Gene Expression Profiling | RNA, Messenger - metabolism | Young Adult | Toll-Like Receptor 6 - genetics | Statistics, Nonparametric | Adult | Female | Toll-Like Receptor 3 - genetics | Toll-Like Receptors - metabolism | Interleukin-6 - metabolism | Severity of Illness Index | Toll-Like Receptor 6 - metabolism | Toll-Like Receptor 7 - genetics | Toll-Like Receptor 5 - metabolism | Toll-Like Receptor 7 - metabolism | Interleukin-6 - genetics | Colitis, Ulcerative - metabolism | Toll-Like Receptor 1 - metabolism | Toll-Like Receptor 4 - genetics | Colitis, Ulcerative - pathology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 3 - metabolism | Toll-Like Receptor 4 - metabolism | Toll-Like Receptor 1 - genetics | Biopsy | Toll-Like Receptors - genetics | Adolescent | Toll-Like Receptor 8 - genetics | Aged | Toll-Like Receptor 9 - metabolism | Toll-Like Receptor 8 - metabolism | Measurement | Toll-like receptors | Messenger RNA | Research | Patient outcomes | Ulcerative colitis | Inflammatory bowel disease | Studies | Proteins | Nutrition research | Gene expression | Manuscripts
Journal Article
Journal of investigative dermatology, ISSN 0022-202X, 2007, Volume 127, Issue 2, pp. 331 - 341
.... Pathogen-associated molecular patterns (PAMPs) are recognized, among others, by Toll-like receptors (TLRs... 
TOLL-LIKE-RECEPTORS | DOUBLE-STRANDED-RNA | DENDRITIC CELLS | SKIN-ASSOCIATED CHEMOKINE | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | INNATE IMMUNE-RESPONSE | INFLAMMATORY PROTEIN 3-ALPHA | NECROSIS-FACTOR-ALPHA | FACTOR-KAPPA-B | HUMAN EPIDERMAL-KERATINOCYTES | DERMATOLOGY | Oligonucleotides - genetics | Phosphorylation | Toll-Like Receptor 5 - genetics | Humans | Toll-Like Receptor 9 - genetics | I-kappa B Proteins - metabolism | RNA, Messenger - metabolism | Flagellin - pharmacology | Tissue Distribution | Cell Nucleus - metabolism | Protein Isoforms - metabolism | Biological Transport | Oligonucleotides - pharmacology | Toll-Like Receptor 3 - genetics | Toll-Like Receptors - metabolism | Chemokine CXCL9 | Toll-Like Receptor 5 - metabolism | Poly I-C - pharmacology | Cytokines - metabolism | Cells, Cultured | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 3 - metabolism | Toll-Like Receptor 4 - metabolism | Chemokine CXCL10 | Transcription Factor RelA - metabolism | Keratinocytes - metabolism | Toll-Like Receptors - genetics | Chemokines, CXC - metabolism | Lipopolysaccharides - pharmacology | CpG Islands | Ligands | Chemokines - metabolism | Toll-Like Receptor 9 - metabolism | CD40 antigen | Oligonucleotides | Flagellin | mRNA | intercellular adhesion molecule 1 | Immunity | Lipopolysaccharides | CXC chemokines | CCL20 protein | Toll-like receptors | CpG islands | TLR7 protein | Dermatology | Keratinocytes | Nuclear transport | Stress | TLR3 protein | TLR9 protein | TLR1 protein | External stimuli | CXCL10 protein | Histocompatibility antigen HLA | Interferon | Internet | Monocyte chemoattractant protein 1 | Tumor necrosis factor- alpha
Journal Article
Clinical & Experimental Immunology, ISSN 0009-9104, 12/2017, Volume 190, Issue 3, pp. 328 - 339
Journal Article
Oncogene, ISSN 1476-5594, 2017, Volume 37, Issue 4, pp. 439 - 449
Toll-like receptor 5 (TLR5) is considered an attractive target for anticancer immunotherapy... 
CTLA-4 BLOCKADE | FLAGELLIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | MURINE MODEL | HEPATIC METASTASES | MELANOMA | ONCOLOGY | GENETICS & HEREDITY | GENE-THERAPY | ANTITUMOR IMMUNITY | RESISTANT PROSTATE-CANCER | TRANSGENIC MOUSE MODEL | AGONIST | Immunotherapy - methods | Killer Cells, Natural | Toll-Like Receptor 5 - genetics | Humans | NF-kappa B - immunology | Peptides - genetics | Male | NF-kappa B - metabolism | Genetic Vectors - therapeutic use | Toll-Like Receptor 5 - agonists | Prostatic Neoplasms - immunology | Prostatic Neoplasms - therapy | Cancer Vaccines - genetics | Prostate - pathology | Signal Transduction - immunology | Cancer Vaccines - therapeutic use | Peptides - metabolism | Prostatic Neoplasms - genetics | Injections, Intralesional | Adjuvants, Immunologic - metabolism | Adenoviridae - genetics | Adjuvants, Immunologic - genetics | Adjuvants, Immunologic - therapeutic use | Toll-Like Receptor 5 - metabolism | Genetic Vectors - immunology | Mice, Inbred C57BL | Peptides - immunology | Genetic Vectors - genetics | Prostatic Neoplasms - mortality | Toll-Like Receptor 5 - immunology | Xenograft Model Antitumor Assays | Cancer Vaccines - immunology | Animals | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Primary Cell Culture | Care and treatment | Immune response | Innovations | Toll-like receptors | Genetic aspects | Health aspects | Cancer | Adenocarcinoma | NF-κB protein | Animal models | TLR5 protein | Tumor cells | Vaccination | Paracrine signalling | Flagellin | Leukocytes (neutrophilic) | Inflammation | Metastasis | Injection | Metastases | Immunotherapy | Antigen (tumor-associated) | Adenoviruses | Antitumor activity | Autocrine signalling | Prostate | Prostate cancer | Tumors | Original
Journal Article
Journal of Neuroimmunology, ISSN 0165-5728, 2006, Volume 181, Issue 1, pp. 46 - 56
In a mouse model of neurocysticercosis, the expression and distribution of Toll‐like receptors (TLRs) was investigated by using both gene array analyses and in situ immunofluorescence microscopy... 
Parasite | Helminth | CNS | Neurocysticercosis | Toll‐like receptors | Toll-like receptors | CELL-WALL COMPONENTS | toll-like receptors | DENDRITIC CELLS | INNATE IMMUNE-RESPONSE | DELTA T-CELLS | IMMUNOLOGY | NEUROSCIENCES | parasite | STREPTOCOCCUS-PNEUMONIAE | LEUKOCYTE MIGRATION | neurocysticercosis | CENTRAL-NERVOUS-SYSTEM | STAPHYLOCOCCUS-AUREUS | helminth | NEURAL STEM-CELL | MISSING LINK | Toll-Like Receptor 5 - genetics | Toll-Like Receptor 9 - genetics | Neurocysticercosis - physiopathology | Mesocestoides | RNA, Messenger - metabolism | Gene Expression - immunology | Cestode Infections - physiopathology | Female | Toll-Like Receptor 3 - genetics | Toll-Like Receptors - metabolism | Cestode Infections - immunology | Brain - parasitology | Disease Models, Animal | Toll-Like Receptor 7 - genetics | Toll-Like Receptor 5 - metabolism | Toll-Like Receptor 7 - metabolism | Cestode Infections - metabolism | Neurocysticercosis - immunology | Toll-Like Receptor 1 - metabolism | Toll-Like Receptor 4 - genetics | Neurocysticercosis - metabolism | Toll-Like Receptor 3 - metabolism | Toll-Like Receptor 4 - metabolism | Toll-Like Receptor 1 - genetics | Animals | Toll-Like Receptors - genetics | Toll-Like Receptor 8 - genetics | Mice | Mice, Inbred BALB C | Toll-Like Receptor 9 - metabolism | Brain - immunology | Toll-Like Receptor 8 - metabolism
Journal Article
PloS one, ISSN 1932-6203, 2009, Volume 4, Issue 6, p. e5990
Journal Article
Journal Article
Immunological Reviews, ISSN 0105-2896, 11/2011, Volume 244, Issue 1, pp. 55 - 74
A large and diverse group of receptors utilizes the family of cytoplasmic signaling proteins known as tumor necrosis factor receptor (TNFR)‐associated factors (TRAFs... 
tumor necrosis factor receptor | lymphocyte activation | signal transduction | tumor necrosis factor receptor associated factor | Signal transduction | Lymphocyte activation | Tumor necrosis factor receptor associated factor | Tumor necrosis factor receptor | CPG OLIGODEOXYNUCLEOTIDES | ACTIVATED PROTEIN-KINASE | HUMAN CD40 RECEPTOR | IMMUNOLOGY | TERMINAL KINASE | LYMPHOTOXIN-BETA-RECEPTOR | TOLL-LIKE RECEPTORS | LATENT MEMBRANE-PROTEIN | FAMILY-MEMBER TALL-1 | NF-KAPPA-B | T-CELLS | Tumor Necrosis Factor-alpha - metabolism | Humans | Protein Processing, Post-Translational - genetics | Tumor Necrosis Factor-alpha - genetics | NF-kappa B - immunology | Ubiquitin - metabolism | Cell Survival - genetics | TNF Receptor-Associated Factor 5 - immunology | NF-kappa B - metabolism | Signal Transduction - immunology | T-Lymphocytes - metabolism | Myeloid Cells - immunology | TNF Receptor-Associated Factor 3 - genetics | Gene Expression - immunology | Tumor Necrosis Factor-alpha - immunology | Protein Processing, Post-Translational - immunology | B-Lymphocytes - metabolism | Receptors, Tumor Necrosis Factor - genetics | Receptors, Tumor Necrosis Factor - metabolism | TNF Receptor-Associated Factor 3 - metabolism | Signal Transduction - genetics | Ubiquitin - genetics | TNF Receptor-Associated Factor 5 - metabolism | Cell Survival - immunology | Immunity, Innate | Mice, Knockout | TNF Receptor-Associated Factor 5 - genetics | Animals | B-Lymphocytes - immunology | NF-kappa B - genetics | TNF Receptor-Associated Factor 3 - immunology | Myeloid Cells - metabolism | Protein Binding | T-Lymphocytes - immunology | Mice | Receptors, Tumor Necrosis Factor - immunology | Ubiquitin - immunology | Ubiquitin | T cells | Tumor necrosis factor | Necrosis | Tumors
Journal Article