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Journal of Immunology, ISSN 0022-1767, 04/2011, Volume 186, Issue 8, pp. 4794 - 4804
Endosomal TLRs play an important role in innate immune response as well as in autoimmune processes. In the therapy of systemic lupus erythematosus,... 
IMMUNOSTIMULATORY CPG-OLIGODEOXYNUCLEOTIDES | CELLS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATION | DNA | COMPLEXES | TOLL-LIKE RECEPTORS | H+-ATPASE | IFN-ALPHA INDUCER | IMMUNOLOGY | NUCLEIC-ACIDS | Humans | Toll-Like Receptor 9 - genetics | Toll-Like Receptor 3 - antagonists & inhibitors | Endosomes - metabolism | Quinolines - pharmacology | Chloroquine - pharmacology | Quinacrine - pharmacology | Transfection | Hydrogen-Ion Concentration - drug effects | HEK293 Cells | Toll-Like Receptors - antagonists & inhibitors | Toll-Like Receptor 3 - genetics | Culture Media - chemistry | Imidazoles - metabolism | Toll-Like Receptor 8 - agonists | Binding, Competitive | Toll-Like Receptor 7 - agonists | Toll-Like Receptor 7 - genetics | Cell Line | Antimalarials - metabolism | Toll-Like Receptor 7 - metabolism | Toll-Like Receptor 9 - antagonists & inhibitors | Cytokines - metabolism | Cells, Cultured | Imidazoles - pharmacology | Nucleic Acids - metabolism | Toll-Like Receptor 3 - metabolism | Toll-Like Receptors - agonists | Antimalarials - pharmacology | Quinolines - metabolism | Animals | Toll-Like Receptors - genetics | Culture Media - pharmacology | Toll-Like Receptor 8 - genetics | Endosomes - chemistry | Toll-Like Receptor 9 - metabolism | Toll-Like Receptor 8 - metabolism | Serum - chemistry | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 02/2017, Volume 23, Issue 2, pp. 174 - 184
Low-grade, chronic inflammation has been associated with many diseases of aging, but the mechanisms responsible for producing this inflammation remain unclear.... 
MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | INTERLEUKIN-18 LEVELS | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CARDIOVASCULAR-DISEASE | RECEPTOR | ESSENTIAL-HYPERTENSION | PROTEINS | T-CELLS | AGE | CELL BIOLOGY | Toll-Like Receptor 5 - genetics | Humans | Middle Aged | Oxidative Stress - immunology | Transcriptome | Immunoblotting | Male | Purinergic P1 Receptor Antagonists - pharmacology | Young Adult | Toll-Like Receptor 8 - immunology | Aging - immunology | Toll-Like Receptor 6 - immunology | Aging - genetics | Calcium-Binding Proteins - immunology | Interleukin-1beta - metabolism | Aged, 80 and over | Caffeine - pharmacology | Hypertension - genetics | Intracellular Signaling Peptides and Proteins - genetics | Interleukin 1 Receptor Antagonist Protein - immunology | Carotid Intima-Media Thickness | Mortality | Neutrophils - drug effects | Hypertension - immunology | Nucleotides - metabolism | Toll-Like Receptor 5 - immunology | Monocytes - drug effects | Regression Analysis | Phenotype | Mice | Calcium-Binding Proteins - genetics | Metabolomics | Pulse Wave Analysis | Neutrophil Activation - drug effects | Cytidine - pharmacology | Interleukin 1 Receptor Antagonist Protein - genetics | Intracellular Signaling Peptides and Proteins - immunology | Cytidine - analogs & derivatives | CARD Signaling Adaptor Proteins - genetics | Toll-Like Receptor 6 - genetics | Adult | Female | Blood Pressure - drug effects | Blood Platelets - drug effects | Macrophages - immunology | Cytokines - immunology | CARD Signaling Adaptor Proteins - immunology | Cell Line | Vascular Stiffness - genetics | Cytokines - metabolism | Oxidative Stress - genetics | Interleukin-1beta - immunology | Adenine - pharmacology | Inflammation - immunology | Inflammasomes - genetics | Vascular Stiffness - immunology | Animals | Inflammasomes - immunology | Toll-Like Receptor 8 - genetics | Inflammation - genetics | Aged | Platelet Activation - drug effects | Genetic aspects | Immune response | Gene expression | Health aspects | Aging | Inflammation | Immune system | Index Medicus
Journal Article
Journal Article
European Journal of Immunology, ISSN 0014-2980, 05/2014, Volume 44, Issue 5, pp. 1503 - 1516
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 02/2017, Volume 19, Issue 1, pp. 39 - 39
Background: Monocytes/macrophages are activated in several autoimmune diseases, including systemic sclerosis (scleroderma; SSc), with increased expression of... 
IFN inducible genes | Monocytes | Toll-like receptor 8 | EBV reactivation | Innate immune response | Systemic sclerosis | CELLS | RECOGNITION | SUBSETS | LUPUS-ERYTHEMATOSUS | RHEUMATOLOGY | CIRCULATING MONOCYTES | TLR AGONISTS | SCLERODERMA | DISEASE | GENE-EXPRESSION | EBV | Herpesvirus 4, Human - genetics | Gene Expression - drug effects | Virus Replication - genetics | Humans | Middle Aged | Immunity, Innate - genetics | Male | Monocytes - metabolism | Monocytes - immunology | Quinolines - pharmacology | Host-Pathogen Interactions - immunology | Young Adult | Toll-Like Receptor 8 - immunology | Gene Expression - immunology | Epstein-Barr Virus Infections - genetics | Adult | Female | Epstein-Barr Virus Infections - virology | Epstein-Barr Virus Infections - immunology | Herpesvirus 4, Human - physiology | Scleroderma, Systemic - metabolism | Cells, Cultured | Herpesvirus 4, Human - immunology | Scleroderma, Systemic - genetics | Gene Expression Profiling - methods | Virus Replication - immunology | Scleroderma, Systemic - immunology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Immunity, Innate - immunology | Monocytes - virology | Host-Pathogen Interactions - genetics | Toll-Like Receptor 8 - genetics | Cell Line, Tumor | Aged | Thiazoles - pharmacology | Virus Replication - physiology | Toll-Like Receptor 8 - metabolism | Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 08/2015, Volume 195, Issue 3, pp. 1100 - 1111
Journal Article
Journal Article
Fish and Shellfish Immunology, ISSN 1050-4648, 11/2016, Volume 58, pp. 309 - 317
Mucosal immune system is one of the most important components in the innate immunity and constitutes the front line of host defense against infection,... 
Scophthalmus maximus | TLR9 | Vibrio anguillarum | TLR8 | Streptococcus iniae | Mucosal tissues | JAPANESE FLOUNDER | CARP | RECOGNITION | SIGNATURES | RNA | IMMUNOLOGY | FISHERIES | MARINE & FRESHWATER BIOLOGY | FISH | VETERINARY SCIENCES | MOLECULAR-CLONING | INNATE IMMUNITY | DNA, Complementary - genetics | Immunity, Innate - genetics | Streptococcal Infections - veterinary | Toll-Like Receptor 9 - genetics | Gene Expression Profiling | Flatfishes - genetics | Phylogeny | Vibrio Infections - immunology | RNA, Messenger - metabolism | Streptococcal Infections - genetics | Fish Proteins - genetics | Vibrio Infections - genetics | Vibrio Infections - microbiology | Fish Diseases - immunology | Vibrio - physiology | Toll-Like Receptor 9 - chemistry | Vibrio Infections - veterinary | Flatfishes - classification | Amino Acid Sequence | Streptococcal Infections - microbiology | Toll-Like Receptor 8 - chemistry | Fish Diseases - microbiology | Fish Proteins - chemistry | RNA, Messenger - genetics | Flatfishes - immunology | Gene Expression Regulation | Fish Proteins - metabolism | Streptococcus iniae - physiology | Fish Diseases - genetics | Sequence Homology, Amino Acid | Animals | Mucous Membrane - immunology | Toll-Like Receptor 8 - genetics | Streptococcal Infections - immunology | Toll-Like Receptor 9 - metabolism | DNA, Complementary - metabolism | Toll-Like Receptor 8 - metabolism | Bacterial infections | Cladistic analysis | Analysis | Fishes | Genes | Genetic research | Amino acids | Skin | Liver | Marine sciences | Index Medicus
Journal Article