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Journal Article
Gastroenterology, ISSN 0016-5085, 2010, Volume 139, Issue 1, pp. 323 - 334.e7
Background & Aims Development of nonalcoholic steatohepatitis (NASH) involves the innate immune system and is mediated by Kupffer cells and hepatic stellate... 
Gastroenterology and Hepatology | Toll-Like Receptors | Nonalcoholic Fatty Liver Diseases | Bambi | Bacterial DNA | FIBROSIS | FATTY LIVER-DISEASE | TRANSGENIC MOUSE | NONALCOHOLIC STEATOHEPATITIS | INCREASED INTESTINAL PERMEABILITY | INSULIN-RESISTANCE | TISSUE INHIBITOR | KUPFFER CELLS | GASTROENTEROLOGY & HEPATOLOGY | HEPATIC STEATOSIS | BACTERIAL-DNA
Journal Article
Circulation Research, ISSN 0009-7330, 01/2013, Volume 112, Issue 1, pp. 103 - 112
RATIONALE:A prothrombotic state and increased platelet reactivity are common in pathophysiological conditions associated with oxidative stress and infections.... 
carboxy(alkylpyrrole) protein adducts | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | HUMAN PLASMA | MACROPHAGES | DEPENDENT PROTEIN-KINASE | MACULAR DEGENERATION | Toll-like receptor 9 | platelets | LOW-DENSITY LIPOPROTEINS | INFLAMMATION | PERIPHERAL VASCULAR DISEASE | OXIDIZED PHOSPHOLIPIDS | CD36 | HEMATOLOGY | oxidative stress | B SCAVENGER RECEPTORS | Toll-Like Receptor 9 - blood | CD36 Antigens - deficiency | Phosphorylation | Blood Platelets - immunology | CD36 Antigens - genetics | Toll-Like Receptor 2 - genetics | Oxidative Stress | Humans | Toll-Like Receptor 9 - genetics | Toll-Like Receptor 2 - deficiency | Transfection | src-Family Kinases - blood | Time Factors | Toll-Like Receptor 6 - genetics | Phosphatidylinositol 3-Kinase - blood | Thrombosis - blood | Genes, Reporter | Disease Models, Animal | Cell Line | Scavenger Receptors, Class B - deficiency | Signal Transduction | Mice, Inbred C57BL | Toll-Like Receptor 9 - deficiency | Myeloid Differentiation Factor 88 - genetics | Thrombosis - immunology | Scavenger Receptors, Class B - genetics | Immunity, Innate | Toll-Like Receptor 6 - deficiency | Mice, Knockout | Platelet Aggregation | Animals | Myeloid Differentiation Factor 88 - deficiency | Blood Platelets - metabolism | Platelet Activation | Proto-Oncogene Proteins c-akt - blood | Ligands | Thrombosis - genetics | Interleukin-1 Receptor-Associated Kinases - blood | Mice | Serum Albumin - metabolism | Index Medicus
Journal Article
Science, ISSN 0036-8075, 9/2010, Volume 329, Issue 5998, pp. 1530 - 1534
Endosomal Toll-like receptors (TLRs) 7 and 9 recognize viral pathogens and induce signals leading to the activation of nuclear factor KB (NF-KB)-dependent... 
T lymphocytes | Molecules | Cytokines | Microscopy | Genes | REPORTS | Toll like receptors | Agonists | Macrophages | Cells | Endosomes | LOCALIZATION | ACTIVATION | DENDRITIC CELLS | TRAF3 | MULTIDISCIPLINARY SCIENCES | TLR9 | TOLL-LIKE-RECEPTOR-9 | INDUCTION | INTERFERON-ALPHA PRODUCTION | I INTERFERON | AP-3 ADAPTER | Recombinant Fusion Proteins - immunology | Dendritic Cells - immunology | Transcriptional Activation | Interferon Type I - immunology | Recombinant Fusion Proteins - metabolism | Endosomes - metabolism | Toll-Like Receptor 9 - immunology | Cytoplasmic Vesicles - metabolism | Interferon Type I - metabolism | Membrane Transport Proteins - metabolism | Cytokines - genetics | Dendritic Cells - metabolism | Macrophages - immunology | Cytokines - immunology | Oligodeoxyribonucleotides - immunology | Cytokines - metabolism | Signal Transduction | Vesicle-Associated Membrane Protein 3 - metabolism | Mice, Inbred C57BL | Cells, Cultured | TNF Receptor-Associated Factor 3 - metabolism | Adaptor Protein Complex beta Subunits | Interferon Regulatory Factor-7 - metabolism | Adaptor Protein Complex 3 - metabolism | Protein Transport | Animals | Adaptor Protein Complex 3 - genetics | Interferon Type I - genetics | Mice | Toll-Like Receptor 9 - metabolism | Myeloid Differentiation Factor 88 - metabolism | Lysosomal-Associated Membrane Protein 2 - metabolism | Cellular control mechanisms | Physiological aspects | TLR7 | Research | Health aspects | Immune system | Proteins | Signal transduction | Interferon | Cellular biology | Index Medicus | Receptors | Compartments | Bifurcations | Activation
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2006, Volume 355, Issue 14, pp. 1445 - 1455
Journal Article
Hepatology, ISSN 0270-9139, 09/2011, Volume 54, Issue 3, pp. 999 - 1008
Sterile inflammatory insults are known to activate innate immunity and propagate organ damage through the recognition of extracellular damage‐associated... 
ISCHEMIA-REPERFUSION INJURY | SYSTEMIC INFLAMMATION | ISCHEMIA/REPERFUSION INJURY | INHIBITION | HMGB1 RELEASE | MEDIATORS | SEPSIS | HMG-1 | GASTROENTEROLOGY & HEPATOLOGY<