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Journal of Immunology, ISSN 0022-1767, 04/2011, Volume 186, Issue 8, pp. 4794 - 4804
Endosomal TLRs play an important role in innate immune response as well as in autoimmune processes. In the therapy of systemic lupus erythematosus,... 
IMMUNOSTIMULATORY CPG-OLIGODEOXYNUCLEOTIDES | CELLS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATION | DNA | COMPLEXES | TOLL-LIKE RECEPTORS | H+-ATPASE | IFN-ALPHA INDUCER | IMMUNOLOGY | NUCLEIC-ACIDS | Humans | Toll-Like Receptor 9 - genetics | Toll-Like Receptor 3 - antagonists & inhibitors | Endosomes - metabolism | Quinolines - pharmacology | Chloroquine - pharmacology | Quinacrine - pharmacology | Transfection | Hydrogen-Ion Concentration - drug effects | HEK293 Cells | Toll-Like Receptors - antagonists & inhibitors | Toll-Like Receptor 3 - genetics | Culture Media - chemistry | Imidazoles - metabolism | Toll-Like Receptor 8 - agonists | Binding, Competitive | Toll-Like Receptor 7 - agonists | Toll-Like Receptor 7 - genetics | Cell Line | Antimalarials - metabolism | Toll-Like Receptor 7 - metabolism | Toll-Like Receptor 9 - antagonists & inhibitors | Cytokines - metabolism | Cells, Cultured | Imidazoles - pharmacology | Nucleic Acids - metabolism | Toll-Like Receptor 3 - metabolism | Toll-Like Receptors - agonists | Antimalarials - pharmacology | Quinolines - metabolism | Animals | Toll-Like Receptors - genetics | Culture Media - pharmacology | Toll-Like Receptor 8 - genetics | Endosomes - chemistry | Toll-Like Receptor 9 - metabolism | Toll-Like Receptor 8 - metabolism | Serum - chemistry | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Science, ISSN 0036-8075, 9/2010, Volume 329, Issue 5998, pp. 1530 - 1534
Endosomal Toll-like receptors (TLRs) 7 and 9 recognize viral pathogens and induce signals leading to the activation of nuclear factor KB (NF-KB)-dependent... 
T lymphocytes | Molecules | Cytokines | Microscopy | Genes | REPORTS | Toll like receptors | Agonists | Macrophages | Cells | Endosomes | LOCALIZATION | ACTIVATION | DENDRITIC CELLS | TRAF3 | MULTIDISCIPLINARY SCIENCES | TLR9 | TOLL-LIKE-RECEPTOR-9 | INDUCTION | INTERFERON-ALPHA PRODUCTION | I INTERFERON | AP-3 ADAPTER | Recombinant Fusion Proteins - immunology | Dendritic Cells - immunology | Transcriptional Activation | Interferon Type I - immunology | Recombinant Fusion Proteins - metabolism | Endosomes - metabolism | Toll-Like Receptor 9 - immunology | Cytoplasmic Vesicles - metabolism | Interferon Type I - metabolism | Membrane Transport Proteins - metabolism | Cytokines - genetics | Dendritic Cells - metabolism | Macrophages - immunology | Cytokines - immunology | Oligodeoxyribonucleotides - immunology | Cytokines - metabolism | Signal Transduction | Vesicle-Associated Membrane Protein 3 - metabolism | Mice, Inbred C57BL | Cells, Cultured | TNF Receptor-Associated Factor 3 - metabolism | Adaptor Protein Complex beta Subunits | Interferon Regulatory Factor-7 - metabolism | Adaptor Protein Complex 3 - metabolism | Protein Transport | Animals | Adaptor Protein Complex 3 - genetics | Interferon Type I - genetics | Mice | Toll-Like Receptor 9 - metabolism | Myeloid Differentiation Factor 88 - metabolism | Lysosomal-Associated Membrane Protein 2 - metabolism | Cellular control mechanisms | Physiological aspects | TLR7 | Research | Health aspects | Immune system | Proteins | Signal transduction | Interferon | Cellular biology | Index Medicus | Receptors | Compartments | Bifurcations | Activation
Journal Article
Nature, ISSN 0028-0836, 02/2012, Volume 482, Issue 7384, pp. 179 - 185
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 02/2007, Volume 127, Issue 2, pp. 331 - 341
Keratinocytes are continuously in contact with external stimuli and have the capacity to produce several soluble mediators. Pathogen-associated molecular... 
TOLL-LIKE-RECEPTORS | DOUBLE-STRANDED-RNA | DENDRITIC CELLS | SKIN-ASSOCIATED CHEMOKINE | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | INNATE IMMUNE-RESPONSE | INFLAMMATORY PROTEIN 3-ALPHA | NECROSIS-FACTOR-ALPHA | FACTOR-KAPPA-B | HUMAN EPIDERMAL-KERATINOCYTES | DERMATOLOGY | Oligonucleotides - genetics | Phosphorylation | Toll-Like Receptor 5 - genetics | Humans | Toll-Like Receptor 9 - genetics | I-kappa B Proteins - metabolism | RNA, Messenger - metabolism | Flagellin - pharmacology | Tissue Distribution | Cell Nucleus - metabolism | Protein Isoforms - metabolism | Biological Transport | Oligonucleotides - pharmacology | Toll-Like Receptor 3 - genetics | Toll-Like Receptors - metabolism | Chemokine CXCL9 | Toll-Like Receptor 5 - metabolism | Poly I-C - pharmacology | Cytokines - metabolism | Cells, Cultured | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 3 - metabolism | Toll-Like Receptor 4 - metabolism | Chemokine CXCL10 | Transcription Factor RelA - metabolism | Keratinocytes - metabolism | Toll-Like Receptors - genetics | Chemokines, CXC - metabolism | Lipopolysaccharides - pharmacology | CpG Islands | Ligands | Chemokines - metabolism | Toll-Like Receptor 9 - metabolism | CD40 antigen | Oligonucleotides | Flagellin | mRNA | intercellular adhesion molecule 1 | Immunity | Lipopolysaccharides | CXC chemokines | CCL20 protein | Toll-like receptors | CpG islands | TLR7 protein | Dermatology | Keratinocytes | Nuclear transport | Stress | TLR3 protein | TLR9 protein | TLR1 protein | External stimuli | CXCL10 protein | Histocompatibility antigen HLA | Interferon | Internet | Monocyte chemoattractant protein 1 | Tumor necrosis factor- alpha | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 05/2012, Volume 484, Issue 7397, pp. 251 - 255
Journal Article
Nature, ISSN 0028-0836, 01/2006, Volume 439, Issue 7073, pp. 208 - 211
Journal Article
Nature Immunology, ISSN 1529-2908, 05/2007, Volume 8, Issue 5, pp. 487 - 496
Journal Article
Journal Article
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