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Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 11/2018, Volume 66, Issue 44, pp. 11672 - 11680
Fatty acid esters of 3-monochloropropane 1,2-diol (3-MCPD) are a group of processing-induced toxicants. To better clarify their possible toxicological effects... 
absorption, distribution, metabolism, and excretion (ADME) | toxicokinetics | UPLC-MS | 3-MCPD dipalmitate | 3-CHLORO-1,2-PROPANEDIOL 3-MCPD | FOOD SCIENCE & TECHNOLOGY | 3-CHLOROPROPANE-1,2-DIOL | TOXICITY | EXCRETION | FATTY-ACID ESTERS | 2-MCPD | IN-VIVO | AGRICULTURE, MULTIDISCIPLINARY | GLYCIDOL | ABSORPTION | CHEMISTRY, APPLIED | CYTOTOXICITY | Index Medicus
Journal Article
Archives of Toxicology, ISSN 0340-5761, 04/2016, Volume 90, Issue 4, pp. 839 - 851
Journal Article
Biological Trace Element Research, ISSN 0163-4984, 12/2017, Volume 180, Issue 2, pp. 275 - 284
This study investigated the toxicity of rats exposed to lead acetate (AcPb) during the second phase of brain development (8–12 days postnatal) in hematological... 
Biochemistry, general | Biotechnology | AChE | Nutrition | Oncology | Hematological | Zinc | Pups | PBG-synthase | Life Sciences | NAC | Lead | Cerebral | ACETYLCHOLINESTERASE ACTIVITY | OXIDATIVE DAMAGE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLUTATHIONE LEVELS | IN-VITRO | POSTNATAL-GROWTH | ENDOCRINOLOGY & METABOLISM | CHELATING-AGENTS | SUCKLING RATS | BRAIN GROWTH | AMINOLEVULINIC-ACID DEHYDRATASE | BINDING | Environmental Pollutants - metabolism | Neuroprotective Agents - metabolism | Neuroprotective Agents - pharmacokinetics | Chlorides - metabolism | Injections, Subcutaneous | Neurons - metabolism | Environmental Pollutants - toxicity | Acetylcysteine - administration & dosage | GPI-Linked Proteins - antagonists & inhibitors | Zinc Compounds - therapeutic use | Lead - toxicity | Animals, Newborn | Biomarkers - metabolism | Lead Poisoning, Nervous System - metabolism | Lead - metabolism | Biomarkers - blood | Random Allocation | Blood-Brain Barrier - metabolism | Toxicokinetics | Porphobilinogen Synthase - blood | Chlorides - administration & dosage | Neurons - enzymology | Porphobilinogen Synthase - antagonists & inhibitors | Zinc Compounds - administration & dosage | Acetylcholinesterase - metabolism | Lead Poisoning, Nervous System - blood | Organometallic Compounds - administration & dosage | Neuroprotective Agents - therapeutic use | Rats, Wistar | Environmental Pollutants - blood | Lead Poisoning, Nervous System - prevention & control | Zinc Compounds - metabolism | Cerebrum - metabolism | Acetylcysteine - therapeutic use | Drug Therapy, Combination | Neurons - drug effects | Neuroprotective Agents - administration & dosage | Cerebrum - drug effects | Nerve Tissue Proteins - antagonists & inhibitors | Tissue Distribution - drug effects | Chlorides - therapeutic use | Blood-Brain Barrier - drug effects | GPI-Linked Proteins - metabolism | Nerve Tissue Proteins - metabolism | Cerebrum - enzymology | Animals | Zinc Compounds - pharmacokinetics | Lead - blood | Chlorides - pharmacokinetics | Brain | Zinc chloride | Hematology | Toxicity | Rats | Acetylcysteine | Exposure | Saline solutions | Sodium chloride | Acetylcholinesterase | Blood | Neurotoxicity | Cerebrum | Hemoglobin | Biomarkers | Inhibition | Pretreatment | Index Medicus
Journal Article
Journal Article
Comparative Biochemistry and Physiology, Part C, ISSN 1532-0456, 01/2019, Volume 215, pp. 18 - 24
While it has been known for a while that some snake species are extremely sensitive to acetaminophen, the underlying mechanism for this toxicity has not been... 
UDP‑glucuronosyltransferase | Mammalia | Acetaminophen | Toxicity | Snake | Biotransformation | N‑acetyltransferase | Reptilia | Phylogeny | ASSAY | UDP-glucuronosyltransferase | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLUCURONIDATION | PARACETAMOL | N-acetyltransferase | ZOOLOGY | METABOLISM | DEACETYLATION | ENDOCRINOLOGY & METABOLISM | TOXICOLOGY | Acetaminophen - adverse effects | Acetaminophen - metabolism | Acetyltransferases - metabolism | Liver - enzymology | Reptilian Proteins - genetics | Species Specificity | Snakes - physiology | Databases, Genetic | Environmental Pollutants - metabolism | Acetyltransferases - genetics | Agkistrodon - genetics | Glucuronosyltransferase - genetics | Glutathione Transferase - genetics | Isoenzymes - metabolism | Analgesics, Non-Narcotic - adverse effects | Colubridae - genetics | Crotalus - physiology | Sulfotransferases - metabolism | Colubridae - physiology | Boidae - physiology | Environmental Pollutants - toxicity | Boidae - genetics | Agkistrodon - physiology | Drug Resistance | Sulfotransferases - genetics | Acetaminophen - toxicity | Isoenzymes - genetics | Glutathione Transferase - metabolism | Analgesics, Non-Narcotic - metabolism | Toxicokinetics | Snakes - genetics | Animals | Glucuronosyltransferase - metabolism | Crotalus - genetics | Reptilian Proteins - metabolism | Animal genetics | Aromatic amines | Metabolites | Gene mutations | Glutathione transferase | Genomics | Turtles | Alligators | Comparative analysis | Snakes | Index Medicus
Journal Article
Comparative Biochemistry and Physiology, Part C, ISSN 1532-0456, 05/2016, Volume 183-184, pp. 1 - 6
A study was carried to test the response of yellow catfish for 28 days under two ammonia concentrations. Weight gain of fish exposure to high and low ammonia... 
Ammonia | Oxidative stress | Immunosuppression | Yellow catfish | Glutamine | MUDSKIPPER PERIOPHTHALMODON-SCHLOSSERI | RAINBOW-TROUT | FOOD CONVERSION EFFICIENCY | BIOCHEMISTRY & MOLECULAR BIOLOGY | HALIBUT HIPPOGLOSSUS-HIPPOGLOSSUS | EXCRETION | NITROGEN-METABOLISM | BOLEOPHTHALMUS-BODDAERTI | ZOOLOGY | GROWTH | ENDOCRINOLOGY & METABOLISM | TOXICOLOGY | HEPATIC-ENCEPHALOPATHY | EXPOSURE | Oxidoreductases - antagonists & inhibitors | Oxidative Stress | Water Pollutants, Chemical - administration & dosage | Catfishes - growth & development | Glutamine - metabolism | Oxidoreductases - chemistry | Glutamine - agonists | Brain - metabolism | Dose-Response Relationship, Drug | Tissue Distribution | Liver - immunology | Liver - drug effects | China | Lipid Peroxidation - drug effects | Catfishes - physiology | Weight Gain - drug effects | Neurons - metabolism | Fish Proteins - antagonists & inhibitors | Neurons - drug effects | Ammonia - poisoning | Immunity, Innate - drug effects | Oxidoreductases - metabolism | Ammonia - metabolism | Liver - metabolism | Neurons - immunology | Fish Proteins - metabolism | Random Allocation | Water Pollutants, Chemical - poisoning | Ammonia - administration & dosage | Ammonium Chloride - administration & dosage | Catfishes - immunology | Brain - drug effects | Toxicokinetics | Fish Proteins - agonists | Water Pollutants, Chemical - metabolism | Animals | Brain - immunology | Aquaculture | Phosphatases | Analysis | Liver | Immunotherapy | Fishes | Physiological aspects | Superoxide | Lysozyme | Index Medicus
Journal Article
Comparative Biochemistry and Physiology, Part C, ISSN 1532-0456, 02/2018, Volume 205, pp. 15 - 25
Journal Article
Archives of Toxicology, ISSN 0340-5761, 2/2016, Volume 90, Issue 2, pp. 291 - 304
The tumour suppressor gene TP53 is mutated in more than 50 % of human tumours, making it one of the most important cancer genes. We have investigated the role... 
Benzo[ a ]pyrene | Biomedicine | Environmental Health | Occupational Medicine/Industrial Medicine | Cytochrome P450 | Carcinogen metabolism | DNA adducts | Pharmacology/Toxicology | Tumour suppressor p53 | Biomedicine general | Benzo[a]pyrene | DNA-ADDUCTS | METABOLIC-ACTIVATION | HUMAN CANCER-CELLS | P53 | RESPONSES | ARISTOLOCHIC ACID I | MESSENGER-RNA | MICE | TOXICOLOGY | EXPRESSION | BENZO(A)PYRENE | DNA Damage - drug effects | Cell Survival - drug effects | Cytochrome P-450 CYP1B1 - genetics | Inactivation, Metabolic | Polycyclic Aromatic Hydrocarbons - pharmacokinetics | Benzo(a)pyrene - toxicity | Polycyclic Aromatic Hydrocarbons - toxicity | Humans | Tumor Suppressor Protein p53 - metabolism | Cytochrome P-450 CYP1B1 - metabolism | NAD(P)H Dehydrogenase (Quinone) - genetics | Cytochrome P-450 CYP1A1 - metabolism | HCT116 Cells - drug effects | Tumor Suppressor Protein p53 - genetics | Carcinogens - toxicity | DNA Adducts | Basic Helix-Loop-Helix Transcription Factors - metabolism | Cytochrome P-450 Enzyme Inducers - poisoning | DNA Damage - genetics | NAD(P)H Dehydrogenase (Quinone) - metabolism | Receptors, Aryl Hydrocarbon - metabolism | Cytochrome P-450 Enzyme Inducers - pharmacology | Toxicity Tests | Cytochrome P-450 Enzyme Inducers - toxicity | Metabolites | Benzopyrene | Analysis | Cytochrome P-450 | Physiological aspects | Tumor proteins | Xenobiotics | Cells | Cytochrome | Carcinogens | Polycyclic aromatic hydrocarbons | Tumors | Index Medicus | Toxicokinetics and Metabolism
Journal Article
Comparative Biochemistry and Physiology, Part C, ISSN 1532-0456, 05/2016, Volume 183-184, pp. 46 - 52
Recently, the detection of pharmaceuticals in surface waters has increased worldwide. Pharmaceuticals are typically found in the environment at concentrations... 
Polymerase chain reaction | BCF | Channel catfish | Benzodiazepine | Endocrine disruption | Steroidogenesis | Bioconcentration | Diazepam | PROTEIN | PHARMACEUTICALS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MODEL | BIOACCUMULATION | ZOOLOGY | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | TOXICOLOGY | Cholesterol Side-Chain Cleavage Enzyme - metabolism | Testis - metabolism | Diazepam - metabolism | GABA Modulators - toxicity | Male | Muscle, Skeletal - metabolism | Diazepam - toxicity | Liver - growth & development | Ovary - growth & development | Testis - drug effects | Cholesterol Side-Chain Cleavage Enzyme - genetics | Tissue Distribution | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Fish Proteins - genetics | Toxicity Tests, Chronic | Liver - drug effects | Water Pollutants, Chemical - blood | Muscle, Skeletal - drug effects | 3-Hydroxysteroid Dehydrogenases - metabolism | Female | Ovary - drug effects | Fish Proteins - antagonists & inhibitors | Ovary - metabolism | Ictaluridae - metabolism | Cholesterol Side-Chain Cleavage Enzyme - antagonists & inhibitors | Muscle, Skeletal - growth & development | Liver - metabolism | GABA Modulators - blood | Gene Expression Regulation, Developmental - drug effects | Fish Proteins - metabolism | Random Allocation | Sex Characteristics | Testis - growth & development | Drug Residues - analysis | Toxicokinetics | Ictaluridae - growth & development | Water Pollutants, Chemical - metabolism | Animals | Water Pollutants, Chemical - toxicity | GABA Modulators - metabolism | Ictaluridae - physiology | Diazepam - blood | 3-Hydroxysteroid Dehydrogenases - genetics | Aquaculture | Gene expression | Analysis | Fishes | Steroid hormones | Cytochrome P-450 | Index Medicus
Journal Article
Reproductive Biology and Endocrinology, ISSN 1477-7827, 11/2014, Volume 12, Issue 1, pp. 102 - 102
Journal Article