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The Journal of clinical investigation, ISSN 0021-9738, 11/2012, Volume 122, Issue 12, pp. 4654 - 4666
Antifibrinolytic drugs are widely used to reduce blood loss during surgery. One serious adverse effect of these drugs is convulsive seizures... 
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Isoflurane - pharmacology | Humans | Middle Aged | Tranexamic Acid - pharmacology | Propofol - pharmacology | Mice, 129 Strain | Anticonvulsants - pharmacology | Receptors, Glycine - antagonists & inhibitors | Seizures - chemically induced | Young Adult | Aprotinin - pharmacology | Spinal Cord - pathology | Neurons - physiology | Aged, 80 and over | Inhibitory Concentration 50 | Adult | Synaptic Transmission - drug effects | Neurons - metabolism | Neurons - drug effects | GABA-A Receptor Antagonists - pharmacology | Binding, Competitive | Membrane Potentials - drug effects | Aminocaproic Acid - adverse effects | GABA-A Receptor Antagonists - pharmacokinetics | Mice, Inbred C57BL | Cells, Cultured | gamma-Aminobutyric Acid - pharmacology | GABA-A Receptor Antagonists - adverse effects | Tranexamic Acid - adverse effects | Aminocaproic Acid - pharmacology | Patch-Clamp Techniques | Animals | Glycine - pharmacology | Protein Binding | Tranexamic Acid - pharmacokinetics | Aged | Mice | Receptors, GABA-A - metabolism | In Vitro Techniques | Inhibitory Postsynaptic Potentials - drug effects | Dose-response relationship (Biochemistry) | Complications and side effects | Care and treatment | Glycine receptors | Tranexamic acid | Research | Seizures (Medicine) | Diagnosis | Properties | Index Medicus | Abridged Index Medicus | Drugs | Neurotransmitters | Side effects | Surgery | Antagonists | Cerebrospinal fluid | Propofol | Anesthetics | Blood | Isoflurane | Seizures
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2013, Volume 368, Issue 2, pp. 128 - 137
Journal Article
The New England journal of medicine, ISSN 1533-4406, 01/2017, Volume 376, Issue 2, pp. 136 - 148
Journal Article
Journal Article
The New England journal of medicine, ISSN 1533-4406, 01/2006, Volume 354, Issue 4, pp. 353 - 365
Journal Article
Journal of Arthroplasty, The, ISSN 0883-5403, 2016, Volume 32, Issue 4, pp. 1298 - 1303
Abstract Background The blood-conserving effect of intravenous (IV) tranexamic acid (TXA) is well-documented for total hip arthroplasty... 
Orthopedics | knee | complications | safety | arthroplasty | hip | tranexamic acid | Life Sciences & Biomedicine | Science & Technology |