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Journal of Biotechnology, ISSN 0168-1656, 04/2012, Volume 158, Issue 4, pp. 184 - 191
► Cofactor-imbalance is a problem in xylose metabolism by recombinant ► NADH-preferable XR, NAD-dependent XDH and XK were overexpressed in Balanced expression... 
Xylose | NADH-preferable xylose reductase | Ethanol | Saccharomyces cerevisiae | STRAINS | XYLITOL DEHYDROGENASE | CONVERSION | PICHIA-STIPITIS | XYLULOKINASE ACTIVITY | PATHWAY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GLUCOSE | GROWTH | FERMENTATION | IMPROVEMENT | Aldehyde Reductase - genetics | D-Xylulose Reductase - genetics | Saccharomyces cerevisiae - genetics | Saccharomyces cerevisiae Proteins - biosynthesis | D-Xylulose Reductase - metabolism | Pichia - enzymology | Xylose - genetics | Saccharomyces cerevisiae - metabolism | Pichia - metabolism | Recombination, Genetic | Aldehyde Reductase - metabolism | Genes, Fungal | NADP - metabolism | NAD - metabolism | Transaldolase - genetics | Gene Expression | Metabolic Engineering - methods | NAD - genetics | Xylose - metabolism | Aerobiosis | Ethanol - metabolism | Phosphotransferases (Alcohol Group Acceptor) - genetics | Aldehyde Oxidoreductases - genetics | Saccharomyces cerevisiae Proteins - genetics | Fermentation | Mutation - genetics | Transaldolase - metabolism | Aldehyde Oxidoreductases - metabolism | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Xylitol - genetics | D-Xylulose Reductase - biosynthesis | Pichia - genetics | Saccharomyces cerevisiae Proteins - metabolism | Saccharomyces cerevisiae - enzymology | Xylitol - metabolism | NADP - genetics | Enzymes | Xylitol | Alcohol, Denatured | Alcohol | Sugars | Production data | Monosaccharides
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 2013, Volume 9, Issue 1, pp. 665 - n/a
Nucleotide degradation is a universal metabolic capability. Here we combine metabolomics, genetics and biochemistry to characterize the yeast pathway. Nutrient... 
nutrient starvation | mass spectrometry | metabolism | autophagy | Saccharomyces cerevisiae | ENCODES | PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | METABOLITE CONCENTRATIONS | TRANSCRIPTION | KINASE | SACCHAROMYCES-CEREVISIAE | GROWTH | GENE-EXPRESSION | AMP-Activated Protein Kinases - metabolism | Saccharomyces cerevisiae - genetics | Purine-Nucleoside Phosphorylase - genetics | Saccharomyces cerevisiae - metabolism | Cyclic AMP-Dependent Protein Kinases - genetics | Purine-Nucleoside Phosphorylase - deficiency | NADP - metabolism | Protein-Serine-Threonine Kinases - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Gene Expression Regulation, Fungal | Glyceraldehyde 3-Phosphate - metabolism | Transaldolase - genetics | Ribose - metabolism | Signal Transduction | Sugar Phosphates | Stress, Physiological - genetics | Protein-Serine-Threonine Kinases - genetics | N-Glycosyl Hydrolases - genetics | Saccharomyces cerevisiae Proteins - genetics | Nucleotides - metabolism | Transaldolase - metabolism | N-Glycosyl Hydrolases - deficiency | Saccharomyces cerevisiae Proteins - metabolism | Pentose Phosphate Pathway - genetics | AMP-Activated Protein Kinases - genetics | Protein kinase A | Glyceraldehyde | Biochemistry | Nucleotides | Phosphatase | Degradation | Proteins | Antioxidants | Pentose | Genetics | Physiology | Consumption | Enzymes | Starvation | Hydrolase | Metabolism | Ablation | Substrates | Software | Phosphates | Oxidative stress | Yeasts | Metabolomics | Yeast | Ribosomes | Genomes | Gene deletion | Kinases | Experiments | Clonal deletion | E coli | Metabolites | Ribose | Phosphate | Deletion | Nutrients | NADP | Biodegradation | Pentose phosphate | Grants | Nitrogen | Carbon | Chromatography | Phosphorylase | Transaldolase | Depletion | Phosphorylases | Pentose phosphate pathway | Nucleosides | Life Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e69558
Coxiella burnetii is an obligate intracellular bacterial pathogen and the causative agent of Q fever. Chronic Q fever can produce debilitating fatigue and C.... 
HEAT-SHOCK PROTEINS | PHAGOSOME MATURATION | SMALL GTPASE RAB7 | MULTIDISCIPLINARY SCIENCES | ENOYL-COA HYDRATASE | INNATE IMMUNE CELLS | CHRONIC Q-FEVER | SACCHAROMYCES-CEREVISIAE | SUPEROXIDE-DISMUTASE | BLOOD MONONUCLEAR-CELLS | PROTEIN IDENTIFICATION DATA | Calgranulin A - metabolism | Vimentin - metabolism | Aldehyde Dehydrogenase, Mitochondrial | Humans | Leucyl Aminopeptidase - metabolism | Electrophoresis, Gel, Two-Dimensional | Monocytes - metabolism | Monocytes - immunology | Q Fever - immunology | Systems Biology | Lysosomes - metabolism | Nicotinamide Phosphoribosyltransferase - metabolism | Time Factors | Mitochondrial Proteins - metabolism | Mass Spectrometry | Chaperonin 60 - metabolism | Proteomics - methods | Aldehyde Dehydrogenase - metabolism | Superoxide Dismutase - metabolism | rab GTP-Binding Proteins - metabolism | Cytokines - metabolism | Enoyl-CoA Hydratase - metabolism | Computational Biology | Transaldolase - metabolism | Pyrophosphatases - metabolism | Protein Processing, Post-Translational | Coxiella burnetii | Proteins | Fluorescence | Health aspects | Analysis | Multiplexing | Pathogens | Laboratories | Gel electrophoresis | Change detection | Two dimensional models | Heat shock proteins | Fatigue | Infections | Biochemistry | Biology | Fever | Host-pathogen interactions | Biological effects | Monocytes | Immunology | Q fever | Medical prognosis | Bacteria | Molecular biology | Two dimensional analysis | Binding sites
Journal Article
Journal of Biotechnology, ISSN 0168-1656, 09/2017, Volume 258, pp. 69 - 78
Journal Article
Applied and Environmental Microbiology, ISSN 0099-2240, 07/2018, Volume 84, Issue 13, p. e00363-18
Clostridium thermosuccinogenes is a thermophilic anaerobic bacterium able to convert various carbohydrates to succinate and acetate as main fermentation... 
Xylulokinase | Carbohydrates | Pentose phosphate | GTP | Dehydrogenases | Genes | Genomes | Malate dehydrogenase | Metabolism | Fermentation | Gene expression | Assaying | Xylose | Transaldolase | Annotations | E coli | Pathways | Malate | Pentose | Pentose phosphate pathway | Bacteria | Acetic acid
Journal Article
Journal Article
Trends in Molecular Medicine, ISSN 1471-4914, 2011, Volume 17, Issue 7, pp. 395 - 403
Metabolism of glucose through the pentose phosphate pathway (PPP) influences the development of diverse pathologies. Hemolytic anemia due to deficiency of PPP... 
Pathology | ACUTE LIVER-FAILURE | MEDICINE, RESEARCH & EXPERIMENTAL | INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-CATENIN | GLUTATHIONE STATUS | CELL BIOLOGY | HEPATOCELLULAR-CARCINOMA | MULTIPLE-SCLEROSIS | NITRIC-OXIDE | GLUCOSE-6-PHOSPHATE-DEHYDROGENASE DEFICIENCY | CARBOHYDRATE-METABOLISM | ALDOSE REDUCTASE | Autoimmunity | Sperm Motility | Oxidative Stress | Fatty Liver - pathology | Humans | Acetylcysteine - metabolism | Male | Carcinoma, Hepatocellular - enzymology | Mitochondria - pathology | Cell Transformation, Neoplastic - metabolism | Transaldolase - metabolism | Infertility, Male - physiopathology | Inflammation - metabolism | Animals | Transaldolase - deficiency | Carcinoma, Hepatocellular - pathology | Glucose - metabolism | Pentose Phosphate Pathway | Phosphates | Glucose metabolism | Oxidative stress | Aldose reductase | Physiological aspects | Development and progression | Inflammation | Glucose | Carcinogenesis | Dextrose | non-alcoholic fatty liver disease | liver | transketolase | aldose reductase | apoptosis | alpha fetoprotein | pentose phosphate pathway | transaldolase | c-jun | β-catenin | carcinogenesis | glucose 6-phosphate dehydrogenase | necrosis | inflammation | mitochondrial transmembrane potential | metabolism | oxidative stress | hepatocellular carcinoma | non-alcoholic steatohepatitis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2018, Volume 115, Issue 43, pp. 11096 - 11101
Journal Article