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Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 4, pp. 352 - 356
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 09/2014, Volume 95, Issue 3, pp. 285 - 293
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 05/2008, Volume 294, Issue 5, pp. 1281 - 1287
Journal Article
Journal Article
by Peng, JH and Cui, T and Huang, F and Chen, L and Zhao, Y and Xu, L and Xu, LL and Feng, Q and Hu, YY
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, ISSN 0022-3565, 03/2013, Volume 344, Issue 3, pp. 646 - 654
Puerarin, an isoflavone component extracted from Kudzu (Pueraria lobata), has been demonstrated to alleviate alcohol-related disorders. Our study examined... 
HEPATITIS | LIPOPOLYSACCHARIDE-BINDING PROTEIN | DISEASE | BARRIER | FATTY LIVER | RATS | ETHANOL | PHARMACOLOGY & PHARMACY | MICE | KAPPA-B | INTESTINAL PERMEABILITY | Toll-Like Receptor 2 - genetics | Membrane Glycoproteins - metabolism | Tight Junctions - genetics | Isoflavones - pharmacology | Male | Alanine Transaminase - blood | Alcohol-Related Disorders - genetics | Antigens, CD - genetics | Receptors, Immunologic - antagonists & inhibitors | Antigens, CD - metabolism | Liver Diseases, Alcoholic - drug therapy | Zonula Occludens-1 Protein - metabolism | Neutrophil Infiltration - drug effects | Disease Models, Animal | Tight Junctions - drug effects | Tight Junctions - metabolism | Zonula Occludens-1 Protein - genetics | Fatty Liver - metabolism | Portal Vein - metabolism | Liver - metabolism | Rats | Toll-Like Receptor 4 - genetics | Toll-Like Receptor 2 - metabolism | Neutrophil Infiltration - genetics | Rats, Sprague-Dawley | Toll-Like Receptor 4 - metabolism | Fatty Liver - drug therapy | Triglycerides - metabolism | Microvilli - genetics | Aspartate Aminotransferases - blood | Diet | Microvilli - metabolism | Receptors, Immunologic - genetics | Intestines - drug effects | Tumor Necrosis Factor-alpha - metabolism | Liver - enzymology | Intestines - metabolism | Acute-Phase Proteins - genetics | Alcohol-Related Disorders - drug therapy | Lipopolysaccharide Receptors - metabolism | Alcohol-Related Disorders - metabolism | Liver Diseases, Alcoholic - genetics | Receptors, Immunologic - biosynthesis | Kupffer Cells - metabolism | Endotoxins - metabolism | Fatty Liver - genetics | Portal Vein - drug effects | Acute-Phase Proteins - metabolism | Endotoxins - genetics | gamma-Glutamyltransferase - metabolism | Antigens, Differentiation, Myelomonocytic - genetics | Liver Diseases, Alcoholic - metabolism | Kupffer Cells - drug effects | Membrane Glycoproteins - genetics | Carrier Proteins - genetics | Microvilli - drug effects | Endotoxins - antagonists & inhibitors | Animals | Carrier Proteins - metabolism | Antigens, Differentiation, Myelomonocytic - metabolism | Lipopolysaccharide Receptors - genetics | Receptors, Immunologic - metabolism
Journal Article
Science, ISSN 0036-8075, 09/2016, Volume 353, Issue 6304, pp. 1161 - 1165
Journal Article
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 06/2009, Volume 296, Issue 6, pp. 1324 - 1331
Interleukin-1 (IL-1) is rapidly expressed in response to tissue damage; however, its role in coordinating the progression from injury to fibrogenesis is not... 
Thioacetamide | Hepatic stellate cell | Matrix metalloproteinase | Bile duct ligation | Carbon tetrachloride | ACTIVATION | PHYSIOLOGY | TGF-BETA | COLLAGEN | carbon tetrachloride | NORMAL RAT-LIVER | thioacetamide | MATRIX METALLOPROTEINASES | bile duct ligation | HEPATIC STELLATE CELLS | MATRIX-METALLOPROTEINASE-9 | matrix metalloproteinase | hepatic stellate cell | EXTRACELLULAR-MATRIX | MICE | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | Interleukin-1 - genetics | Thioacetamide - pharmacology | Liver - pathology | Gene Expression - drug effects | Gene Expression - genetics | Receptors, Interleukin-1 - genetics | Actins - metabolism | Hepatic Stellate Cells - metabolism | Male | Interleukin-1beta - genetics | Liver Cirrhosis - chemically induced | Tissue Inhibitor of Metalloproteinase-2 - genetics | Actins - genetics | Matrix Metalloproteinase 9 - metabolism | Collagen Type I - genetics | Liver - drug effects | Matrix Metalloproteinase 9 - genetics | Liver Cirrhosis - metabolism | Interleukin-1alpha - genetics | Hepatic Stellate Cells - drug effects | Liver Cirrhosis - etiology | Matrix Metalloproteinase 2 - metabolism | Liver - metabolism | Matrix Metalloproteinase 13 - genetics | Mice, Inbred C57BL | Collagen Type III - genetics | Mice, Inbred Strains | Mice, Knockout | Tissue Inhibitor of Metalloproteinase-1 - genetics | Animals | Transforming Growth Factor beta - genetics | Liver Cirrhosis - pathology | Mice | Mice, Inbred BALB C | Alanine Transaminase - metabolism | Index Medicus | Mediators | Inflammation | Immunity
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 03/2010, Volume 298, Issue 3, pp. G364 - G374
Shen Z, Liang X, Rogers CQ, Rideout D, You M. Involvement of adiponectin-SIRT1-AMPK signaling in the protective action of rosiglitazone against alcoholic fatty... 
Signal transduction | Acetylation | Lipid metabolism | Transcriptional regulators | DIETARY SATURATED FAT | PHYSIOLOGY | ACTIVATED PROTEIN-KINASE | LIPID-METABOLISM | signal transduction | lipid metabolism | PHOSPHATIDATE PHOSPHOHYDROLASE | TNF-ALPHA PRODUCTION | SIRT1 | acetylation | MAMMALIAN SIRTUIN-1 | GENE-EXPRESSION | transcriptional regulators | ETHANOL | GASTROENTEROLOGY & HEPATOLOGY | HEPATIC STEATOSIS | RNA, Small Interfering - genetics | Liver - pathology | Gene Expression - genetics | Tumor Necrosis Factor-alpha - genetics | Ion Channels - genetics | Male | Fatty Liver, Alcoholic - metabolism | Liver - drug effects | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Lipid Metabolism - genetics | Thiazolidinediones - pharmacology | PPAR gamma - genetics | Adiponectin - pharmacology | Liver - metabolism | Rats | Intra-Abdominal Fat - metabolism | Phosphatidate Phosphatase | Triglycerides - metabolism | Acetylation - drug effects | Signal Transduction - drug effects | Models, Biological | Cell Line, Tumor | Transaminases - blood | Mice | Transcription Factors | Histones - metabolism | AMP-Activated Protein Kinases - genetics | Acetyl-CoA Carboxylase - metabolism | Receptors, Adiponectin - genetics | Sirtuin 1 - metabolism | AMP-Activated Protein Kinases - metabolism | Gene Expression - drug effects | Mitochondrial Proteins - genetics | Adiponectin - physiology | Fatty Liver, Alcoholic - prevention & control | Sirtuin 1 - genetics | Fatty Liver, Alcoholic - blood | Thiazolidinediones - therapeutic use | Trans-Activators - genetics | Intra-Abdominal Fat - drug effects | Fatty Liver, Alcoholic - pathology | Nuclear Proteins - genetics | Mice, Inbred C57BL | Nuclear Proteins - metabolism | Ethanol - pharmacology | Animals | Lipid Metabolism - drug effects | Retinoid X Receptor alpha - genetics | Triglycerides - blood | Signal Transduction - physiology | Trans-Activators - metabolism | Uncoupling Protein 2 | Fatty liver | Physiological aspects | Cellular signal transduction | Research | Rosiglitazone maleate | Health aspects | Protein kinases | Hormones and Signaling
Journal Article
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2018, Volume 378, Issue 12, pp. 1096 - 1106
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 04/2012, Volume 45, Issue 5, pp. 708 - 715
Ferulic acid (FA), a phenolic compound found in various medicinal plants, has hepatoprotective effects against oxidative stress and inflammation. Here, we... 
Oxidative stress | Ischemia/reperfusion | Liver | Apoptosis | Ferulic acid | NEONATAL-RAT CARDIOMYOCYTES | N-TERMINAL KINASE | CELL-DEATH | MITOCHONDRIAL PERMEABILITY TRANSITION | SODIUM FERULATE | NECROSIS | HEPATIC ISCHEMIA-REPERFUSION | LIVER-INJURY | IN-VIVO | PHARMACOLOGY & PHARMACY | Apoptosis - drug effects | Tumor Necrosis Factor-alpha - blood | Tumor Necrosis Factor-alpha - genetics | Caspase 3 - metabolism | Reperfusion Injury - drug therapy | Apoptosis - genetics | Male | BH3 Interacting Domain Death Agonist Protein - genetics | TNF Receptor-Associated Death Domain Protein - genetics | Liver - drug effects | Caspase 3 - genetics | Lipid Peroxidation - drug effects | TNF Receptor-Associated Death Domain Protein - metabolism | Membrane Proteins - genetics | Liver - metabolism | bcl-2-Associated X Protein - metabolism | Apoptosis Regulatory Proteins - metabolism | Signal Transduction - drug effects | MAP Kinase Kinase 4 - genetics | Cytosol - metabolism | Transaminases - blood | Mice | Oxidative Stress - drug effects | Tumor Necrosis Factor-alpha - metabolism | Glutathione - metabolism | TNF Receptor-Associated Factor 2 - genetics | Caspase 8 - metabolism | Cytosol - drug effects | Cytochromes c - genetics | Hepatocytes - metabolism | Caspase 8 - genetics | Glutathione - genetics | MAP Kinase Kinase 4 - metabolism | Bcl-2-Like Protein 11 | Apoptosis Regulatory Proteins - genetics | MAP Kinase Kinase 4 - antagonists & inhibitors | Membrane Proteins - metabolism | Reperfusion Injury - genetics | Reperfusion Injury - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | Hepatocytes - drug effects | bcl-2-Associated X Protein - genetics | Proto-Oncogene Proteins - metabolism | Reperfusion Injury - pathology | Cytochromes c - metabolism | TNF Receptor-Associated Factor 2 - metabolism | Proto-Oncogene Proteins - genetics | Up-Regulation - genetics | Mice, Inbred ICR | Up-Regulation - drug effects | Liver - blood supply | Animals | Coumaric Acids - pharmacology | Ischemia
Journal Article