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Diabetologia, ISSN 0012-186X, 12/2011, Volume 54, Issue 12, pp. 3132 - 3142
Journal Article
STEM CELLS, ISSN 1066-5099, 10/2017, Volume 35, Issue 10, pp. 2184 - 2197
Journal Article
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 10/2011, Volume 43, Issue 10, pp. 964 - 970
Journal Article
Diabetes, ISSN 0012-1797, 03/2018, Volume 67, Issue 3, pp. 437 - 447
Polymorphism in TCF7L2, a component of the canonical Wnt signaling pathway, has a strong association with beta-cell dysfunction and type 2 diabetes through a... 
VARIANTS | GLUCOSE-METABOLISM | CLONING | TRANSCRIPTION-FACTOR-7-LIKE-2 TCF7L2 GENE | INSULIN-SECRETION | MOUSE | ENDOCRINOLOGY & METABOLISM | RISK | EXPRESSION | BETA-CATENIN/TCF-4 | DELETION | Glucose Intolerance - metabolism | Recombinant Proteins - therapeutic use | Bone Morphogenetic Protein 4 - genetics | Bacterial Proteins - chemistry | Male | Glucose Intolerance - pathology | Bone Morphogenetic Protein 4 - metabolism | Recombinant Fusion Proteins - metabolism | Transcription Factor 7-Like 2 Protein - metabolism | Glucose Intolerance - drug therapy | Transcription Factor 7-Like 2 Protein - chemistry | Insulin-Secreting Cells - metabolism | Pericytes - pathology | Luminescent Proteins - chemistry | Cell Differentiation | Insulin Secretion | Glucose Intolerance - physiopathology | Recombinant Proteins - metabolism | Bone Morphogenetic Protein 4 - therapeutic use | Transcription Factor 7-Like 2 Protein - genetics | Tissue Culture Techniques | Pericytes - metabolism | Bacterial Proteins - genetics | Gene Expression Regulation | Cell Communication | Cellular Microenvironment | Mice, Transgenic | Recombinant Fusion Proteins - chemistry | Insulin - metabolism | Animals | Glucose - metabolism | Bacterial Proteins - metabolism | Ligands | Luminescent Proteins - genetics | Insulin-Secreting Cells - pathology | Mutation | Luminescent Proteins - metabolism | Usage | Genetic aspects | Research | B cells | Diabetes | Diagnosis | Glucose tolerance tests | Genetic polymorphisms
Journal Article
Journal Article
Human molecular genetics, ISSN 0964-6906, 12/2014, Volume 23, Issue 24, pp. 6419 - 6431
Genome-wide association studies have revealed > 60 loci associated with type 2 diabetes ( T2D), but the underlying causal variants and functional mechanisms... 
PROVIDES INSIGHTS | COMMON VARIANTS | RISK LOCI | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUSCEPTIBILITY | GENETICS & HEREDITY | GENE-EXPRESSION | PANCREATIC BETA-CELLS | TYPE-2 DIABETES-MELLITUS | PROINSULIN LEVELS | GENOME-WIDE ASSOCIATION | ADIPOSE-TISSUE | LIM-Homeodomain Proteins - metabolism | Proinsulin - metabolism | Diabetes Mellitus, Type 2 - genetics | Homeodomain Proteins - metabolism | Humans | Diabetes Mellitus, Type 2 - metabolism | Genetic Loci | Transcription Factor 7-Like 2 Protein - metabolism | Maf Transcription Factors, Large - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Maf Transcription Factors, Large - genetics | Islets of Langerhans - metabolism | Trans-Activators - genetics | Transcription, Genetic | Insulin - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Basic Helix-Loop-Helix Transcription Factors - genetics | Transcription Factor 7-Like 2 Protein - genetics | Islets of Langerhans - pathology | Signal Transduction | Gene Expression Regulation | Mice, Transgenic | Proinsulin - genetics | Transcription Factors - genetics | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Insulin - metabolism | LIM-Homeodomain Proteins - genetics | Animals | Alleles | Trans-Activators - metabolism | High-Throughput Nucleotide Sequencing | Mice | Polymorphism, Single Nucleotide | Diabetes Mellitus, Type 2 - pathology | Biological Sciences | Biochemistry and Molecular Biology | Naturvetenskap | Natural Sciences | Biokemi och molekylärbiologi | Biologiska vetenskaper
Journal Article