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Journal of Clinical Investigation, ISSN 0021-9738, 12/2010, Volume 120, Issue 12, pp. 4289 - 4302
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 2015, Volume 35, Issue 9, pp. 1523 - 1532
Journal Article
Oncogene, ISSN 0950-9232, 06/2012, Volume 31, Issue 23, pp. 2824 - 2835
Somatotrophs produce growth hormone (GH) and are the most abundant secretory cells of the pituitary. Somatotrophs express the transcription factor Pit-1 and... 
p19Arf | apoptosis | OIA | dependence receptor | Pit-1 | p53 | RB+/-MICE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYCLE ARREST | RET-GENE-EXPRESSION | P53 PATHWAY | CELL BIOLOGY | NONCODING RNA | ONCOLOGY | REGULATES P53-DEPENDENT APOPTOSIS | GROWTH | GENETICS & HEREDITY | SENESCENCE | ARF TUMOR-SUPPRESSOR | DAP KINASE | Somatotrophs - metabolism | RNA, Small Interfering - genetics | Proto-Oncogene Proteins c-ret - metabolism | Somatotrophs - pathology | Transcription Factor Pit-1 - metabolism | Regulatory Sequences, Nucleic Acid | Cells, Cultured | Tumor Suppressor Protein p53 - metabolism | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Rats | Cyclin-Dependent Kinase Inhibitor p16 - antagonists & inhibitors | Promoter Regions, Genetic - genetics | Tumor Suppressor Protein p53 - genetics | Transcription Factor Pit-1 - genetics | Animals | Chromatin Immunoprecipitation | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Transcription Factor Pit-1 - antagonists & inhibitors | Proto-Oncogene Proteins c-ret - antagonists & inhibitors | Apoptosis | Proto-Oncogene Proteins c-ret - genetics | Somatotropin | Transcription factors | Physiological aspects | Genetic aspects | Research | Gene expression | Health aspects | Pituitary gland | Oncology | Cellular biology | Index Medicus | Cell culture | Glial cell line-derived neurotrophic factor | Acromegaly | siRNA | Promoters | p53 protein | ARF protein | Pit1 protein | Ret protein | p19ARF gene | Pituitary | Differentiation | Growth hormone | Metabolic disorders | Oncogenes
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 514, Issue 7521, pp. 257 - 261
Journal Article
BMC Endocrine Disorders, ISSN 1472-6823, 09/2017, Volume 17, Issue 1, pp. 54 - 54
Background: A functional pituitary adenoma can produce multiple anterior-pituitary hormones, such as growth hormone (GH) producing adenomas (GHoma) with... 
GHoma | Case report | Transcriptional factor | Subclinical Cushing's disease | Pituitary adenoma | TRANSCRIPTION | ACTH | GROWTH-HORMONE | ENDOCRINOLOGY & METABOLISM | EXPRESSION | MODULATION | ADRENOCORTICOTROPIC HORMONE | AXIS | Pituitary ACTH Hypersecretion - pathology | Transcription Factor Pit-1 - metabolism | Adenoma - genetics | Pituitary Neoplasms - genetics | Homeodomain Proteins - metabolism | Humans | Middle Aged | Male | Pituitary Neoplasms - pathology | T-Box Domain Proteins - genetics | Homeodomain Proteins - genetics | Pituitary Neoplasms - complications | T-Box Domain Proteins - metabolism | Acromegaly - complications | Transcription Factor Pit-1 - genetics | Adenoma - complications | Pituitary ACTH Hypersecretion - complications | Adenoma - pathology | Acromegaly - pathology | Diabetes Mellitus, Type 2 - complications | Transcription factors | Pituitary gland tumors | Analysis | Cancer cells | Cushing syndrome | Acromegaly | Physiological aspects | Genetic aspects | Immunohistochemistry | Cell culture | Nuclear magnetic resonance--NMR | Transcription | Adrenal glands | Tissue culture | Proopiomelanocortin | Insulin-like growth factors | Coexistence | Adenoma | Pit1 protein | Prolactin | Surgery | Stains | Nervous system diseases | Tumor cells | Pituitary (anterior) | Gene expression | Beta2 protein | Thyroid-stimulating hormone | Adrenocorticotropic hormone | Growth hormones | Growth hormone | Tumors | Index Medicus
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 16, pp. 14456 - 14471
The POU class 1 homeobox 1 (POU1F1, also known as Pit-1), pertaining to the Pit-Oct-Unc (POU) family of transcription factors, has been related to tumor growth... 
Breast cancer | Brca1 | Vitamin D | Cisplatin | Pit-1 | breast cancer | BRCA1 | cisplatin | vitamin D | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2013, Volume 123, Issue 2, pp. 812 - 822
Journal Article
Human Gene Therapy, ISSN 1043-0342, 01/2012, Volume 23, Issue 1, pp. 14 - 114
The treatment of growth hormone (GH)- and prolactin (PRL)-secreting tumors resistant to current therapeutic molecules (somatostatin and dopamine analogues)... 
Research Articles | MEDICINE, RESEARCH & EXPERIMENTAL | HUMAN BREAST | RNA | PROLIFERATION | IN-VITRO | GROWTH-HORMONE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | GENE-EXPRESSION | MUTATIONS | SOMATOTROPH ADENOMAS | PITX2 | PITUITARY-HORMONE DEFICIENCY | Human Growth Hormone - analysis | Cell Proliferation | Transcription Factor Pit-1 - metabolism | Genetic Vectors - administration & dosage | Adenoma - genetics | Humans | Transcriptional Activation | Growth Hormone-Secreting Pituitary Adenoma - genetics | Green Fluorescent Proteins - genetics | Genetic Vectors - therapeutic use | Tryptophan - metabolism | Adenoma - metabolism | Prolactinoma - genetics | Lentivirus - metabolism | Adenoma - therapy | Growth Hormone-Secreting Pituitary Adenoma - metabolism | Transcription Factor Pit-1 - genetics | Pituitary Neoplasms - therapy | Prolactinoma - therapy | Arginine - genetics | Cell Death | Female | Lentivirus - genetics | Tumor Cells, Cultured | Transgenes | Prolactin - secretion | Gene Transfer Techniques | Green Fluorescent Proteins - metabolism | Growth Hormone-Secreting Pituitary Adenoma - therapy | Cell Survival | Pituitary Neoplasms - genetics | Tryptophan - genetics | Genetic Vectors - metabolism | Pituitary Neoplasms - metabolism | Blotting, Western | Genetic Vectors - genetics | Prolactin - blood | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Mice | Prolactin - analysis | Arginine - metabolism | Human Growth Hormone - secretion | Cell Transplantation - methods | Genetic Therapy - methods | Index Medicus | Life Sciences
Journal Article