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Journal of clinical immunology, ISSN 1573-2592, 2011, Volume 31, Issue 3, pp. 472 - 478
Leptin, one of the adipokines, functions as a hormone and a cytokine. In this investigation, we show for the first time that leptin, in a... 
Medical Microbiology | Biomedicine | Immunology | Internal Medicine | Infectious Diseases | activation markers | cytokines | B cells | PROTEIN-KINASE | TRANSDUCER | RECEPTOR | PROLIFERATION | IMMUNOLOGY | BLOOD MONONUCLEAR-CELLS | DEFICIENCY | PI3K/AKT | IMMUNE-RESPONSES | T-CELLS | Autoimmunity | Interleukin-6 - analysis | Janus Kinase 2 - biosynthesis | Mitogen-Activated Protein Kinase 3 - analysis | Humans | p38 Mitogen-Activated Protein Kinases - biosynthesis | p38 Mitogen-Activated Protein Kinases - analysis | Dose-Response Relationship, Drug | Signal Transduction - immunology | Inflammation - metabolism | Mitogen-Activated Protein Kinases - analysis | Mitogen-Activated Protein Kinase 3 - biosynthesis | Mitogen-Activated Protein Kinase 6 - analysis | Leptin - pharmacology | Phosphorylation - drug effects | Interleukin-10 - analysis | B-Lymphocytes - metabolism | Janus Kinase 2 - analysis | Enzyme-Linked Immunosorbent Assay | Lymphocyte Activation | Cells, Cultured | Mitogen-Activated Protein Kinases - biosynthesis | Receptors, Leptin - immunology | STAT3 Transcription Factor - analysis | Inflammation - immunology | Tumor Necrosis Factor-alpha - analysis | STAT3 Transcription Factor - biosynthesis | B-Lymphocytes - drug effects | B-Lymphocytes - immunology | Mitogen-Activated Protein Kinase 6 - biosynthesis | Interleukin-6 - biosynthesis | Interleukin-10 - biosynthesis | Receptors, Leptin - metabolism | Tumor Necrosis Factor-alpha - biosynthesis
Journal Article
Journal Article
The Plant cell, ISSN 1532-298X, 2011, Volume 23, Issue 4, pp. 1639 - 1653
Journal Article
Journal Article
Nature genetics, ISSN 1546-1718, 2015, Volume 47, Issue 12, pp. 1475 - 1481
.... Here we show that the activity of this pathway is highly heterogeneous and is regulated by NRF2, a transcription factor frequently deregulated in NSCLC... 
ACTIVATION | PROTEIN | GLUTAMINE | PATHWAY | GLUCOSE | GROWTH | GENETICS & HEREDITY | GENE-EXPRESSION | IMPAIR | CARCINOMA | KEAP1 MUTATIONS | RNA, Small Interfering - genetics | NF-E2-Related Factor 2 - antagonists & inhibitors | Cell Proliferation | Lung Neoplasms - mortality | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Serine - biosynthesis | Immunoenzyme Techniques | Adenocarcinoma - metabolism | Carcinoma, Non-Small-Cell Lung - secondary | Biomarkers, Tumor - metabolism | NF-E2-Related Factor 2 - genetics | Adenocarcinoma - genetics | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Lung Neoplasms - genetics | Carcinoma, Non-Small-Cell Lung - genetics | RNA, Messenger - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Carcinoma, Non-Small-Cell Lung - mortality | Adenocarcinoma - secondary | Blotting, Western | Xenograft Model Antitumor Assays | Animals | NF-E2-Related Factor 2 - metabolism | Biomarkers, Tumor - genetics | Mice | Adenocarcinoma - mortality | Apoptosis | Transcription factors | Cell metabolism | Development and progression | Genetic aspects | Genetic transcription | Lung cancer, Non-small cell | Properties | Health aspects | Medical research | Enzymes | Lung cancer | Biosynthesis | RNA polymerase | Metabolism | Gene expression | Experiments | Metabolites | Scientific imaging | Tumorigenesis | Labeling | Bioinformatics | Mass spectrometry
Journal Article
Journal Article
The Plant cell, ISSN 1532-298X, 2011, Volume 23, Issue 10, pp. 3853 - 3865
Legume GRAS (GAI, RGA, SCR)-type transcription factors MODULATION SIGNALING PATHWAY1 (NSP1... 
Symbiosis | Legumes | Transcription factors | Root exudates | Genes | Plant roots | Biosynthesis | Rhizobium | Plants | Rice | phosphate deficiency | red-clover | tiller bud outgrowth | arbuscular mycorrhizal fungi | affymetrix genechip data | germination stimulants | quality assessment | lotus-japonicus | transduction pathway | parasitic plants | PHOSPHATE DEFICIENCY | ARBUSCULAR MYCORRHIZAL FUNGI | TILLER BUD OUTGROWTH | BIOCHEMISTRY & MOLECULAR BIOLOGY | QUALITY ASSESSMENT | TRANSDUCTION PATHWAY | PLANT SCIENCES | CELL BIOLOGY | GERMINATION STIMULANTS | RED-CLOVER | LOTUS-JAPONICUS | AFFYMETRIX GENECHIP DATA | PARASITIC PLANTS | Carotenoids - analysis | Medicago truncatula - genetics | Sesquiterpenes - metabolism | Oligonucleotide Array Sequence Analysis | Sinorhizobium meliloti - physiology | Molecular Sequence Data | Plant Roots - genetics | Gene Expression Profiling | Medicago truncatula - microbiology | Phylogeny | Lactones - analysis | Plant Roots - physiology | Oryza - growth & development | Oryza - genetics | Oryza - microbiology | Gene Expression Regulation, Plant | Plant Proteins - metabolism | Plant Roots - growth & development | Lactones - chemistry | Amino Acid Sequence | Signal Transduction | Medicago truncatula - growth & development | Down-Regulation | Oryza - physiology | Transcription Factors - genetics | Lactones - metabolism | Plant Roots - microbiology | Transcription Factors - metabolism | Medicago truncatula - physiology | Plant Proteins - genetics | Phenotype | Plant Root Nodulation | Carotenoids - metabolism | Mutation | Plant Growth Regulators - metabolism | Beans | Plant genetics | Physiological aspects | Genetic aspects | Research | Mimosaceae | Lactones
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 2004, Volume 172, Issue 1, pp. 567 - 576
The signaling mechanism by which the anti-inflammatory cytokine IL-10 mediates suppression of proinflammatory cytokine synthesis remains largely unknown.... 
RHEUMATOID-ARTHRITIS | TUMOR-NECROSIS-FACTOR | DNA-BINDING | HUMAN NEUTROPHILS | TYROSINE PHOSPHORYLATION | INTERLEUKIN-10 RECEPTOR | GENE-EXPRESSION | KAPPA-B-ALPHA | IMMUNOLOGY | HUMAN MONOCYTES | MONONUCLEAR PHAGOCYTES | Protein Binding - genetics | Protein Biosynthesis | Interleukin-6 - antagonists & inhibitors | Humans | Tumor Necrosis Factor-alpha - genetics | Immunoglobulins - genetics | Lipopolysaccharides - antagonists & inhibitors | RNA, Messenger - metabolism | Suppressor of Cytokine Signaling Proteins | Repressor Proteins - antagonists & inhibitors | Antigens, CD - metabolism | Trans-Activators - physiology | Protein Tyrosine Phosphatases - antagonists & inhibitors | RNA, Messenger - biosynthesis | Protein Tyrosine Phosphatases - genetics | Inflammation Mediators - physiology | Glycoproteins - genetics | DNA-Binding Proteins - physiology | Protein Tyrosine Phosphatases - biosynthesis | DNA-Binding Proteins - antagonists & inhibitors | Signal Transduction - genetics | DNA - metabolism | Down-Regulation - genetics | Macrophages - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 2 | Repressor Proteins - biosynthesis | Up-Regulation - immunology | Interleukin-10 - antagonists & inhibitors | Lipopolysaccharides - pharmacology | Adenoviruses, Human - genetics | Interleukin-10 - immunology | Tumor Necrosis Factor-alpha - biosynthesis | Phosphorylation | Tissue Inhibitor of Metalloproteinase-1 - biosynthesis | Antigens, CD - biosynthesis | Receptors, Cell Surface | Receptors, IgG - biosynthesis | Receptors, IgG - antagonists & inhibitors | Interleukin-10 - physiology | Signal Transduction - immunology | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Signaling Lymphocytic Activation Molecule Family Member 1 | Receptors, Tumor Necrosis Factor - antagonists & inhibitors | RNA, Messenger - antagonists & inhibitors | Receptors, Tumor Necrosis Factor, Type II | Trans-Activators - genetics | Inflammation Mediators - antagonists & inhibitors | Trans-Activators - biosynthesis | Immunoglobulins - biosynthesis | Macrophages - immunology | Inflammation Mediators - immunology | Receptors, Tumor Necrosis Factor - metabolism | Immune Sera - pharmacology | Proteins - physiology | Cells, Cultured | Glycoproteins - antagonists & inhibitors | Histocompatibility Antigens Class II - biosynthesis | Tissue Inhibitor of Metalloproteinase-1 - antagonists & inhibitors | Transcription Factors - antagonists & inhibitors | Transcription Factors - biosynthesis | Up-Regulation - genetics | DNA-Binding Proteins - genetics | DNA - antagonists & inhibitors | Glycoproteins - biosynthesis | Suppressor of Cytokine Signaling 3 Protein | Down-Regulation - immunology | Interleukin-6 - biosynthesis | Receptors, Tumor Necrosis Factor - biosynthesis | STAT3 Transcription Factor | Trans-Activators - antagonists & inhibitors | Genetic Vectors | DNA-Binding Proteins - biosynthesis | Tumor Necrosis Factor-alpha - antagonists & inhibitors
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2009, Volume 324, Issue 5927, pp. 651 - 654
...⁺) biosynthesis, nicotinamide phosphoribosyltransferase (NAMPT), and levels of NAD⁺ display circadian oscillations that are regulated by the core clock machinery in mice... 
RNA | Hepatocytes | Liver | Genes | Oscillation | Control loops | Reports | Biosynthesis | Gene expression regulation | Metabolism | Research universities | LIFE-SPAN | CELLS | GLUCOSE-HOMEOSTASIS | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE | EXTENSION | COMPONENT | SIRT1 | BINDING | CALORIE RESTRICTION | Humans | Adipose Tissue, White - metabolism | Hepatocytes - metabolism | Nicotinamide Phosphoribosyltransferase - antagonists & inhibitors | Basic Helix-Loop-Helix Transcription Factors - metabolism | Nicotinamide Phosphoribosyltransferase - metabolism | Piperidines - pharmacology | Sirtuin 1 | NAD - biosynthesis | Trans-Activators - genetics | Cell Cycle Proteins - genetics | Transcription, Genetic | Biological Clocks | Nuclear Proteins - genetics | Acrylamides - pharmacology | Cytokines - genetics | ARNTL Transcription Factors | Cell Line | Basic Helix-Loop-Helix Transcription Factors - genetics | Cytokines - metabolism | Liver - metabolism | Enzyme Inhibitors - pharmacology | Gene Expression Regulation | Transcription Factors - genetics | Circadian Rhythm | Period Circadian Proteins | Feedback, Physiological | Nicotinamide Phosphoribosyltransferase - genetics | Animals | CLOCK Proteins | Cell Line, Tumor | Protein Binding | Trans-Activators - metabolism | Mice | Cytokines - antagonists & inhibitors | Sirtuins - metabolism | Enzymes | Circadian rhythm | Cellular biology | Animal behavior | Rodents
Journal Article