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Cell, ISSN 0092-8674, 01/2014, Volume 156, Issue 3, pp. 577 - 589
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2008, Volume 29, Issue 1, pp. 92 - 101
Transcriptional activators, several different coactivators, and general transcription factors are necessary to access specific loci in the dense chromatin... 
DNA | UBIQUITINATION | COMPLEX | ACTIVATION | UBP8 | CHROMATIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | UBIQUITYLATION | DEUBIQUITYLATION | MESSENGER-RNA EXPORT | SAGA | CELL BIOLOGY | Transcription Factors - chemistry | p300-CBP Transcription Factors - physiology | Histone Acetyltransferases - chemistry | Humans | Recombinant Fusion Proteins - physiology | Molecular Sequence Data | Trans-Activators - chemistry | Drosophila melanogaster - genetics | Promoter Regions, Genetic - genetics | Trans-Activators - physiology | Drosophila melanogaster - metabolism | Drosophila Proteins - physiology | Endopeptidases - chemistry | Conserved Sequence | Ubiquitination - physiology | p300-CBP Transcription Factors - chemistry | Amino Acid Sequence | Cell Line | Transcription Factors - physiology | Transcription Factors, General - chemistry | Animals, Genetically Modified | Gene Silencing | Thiolester Hydrolases - physiology | RNA Polymerase II - physiology | Drosophila Proteins - chemistry | Transcription Factors - genetics | Histone Acetyltransferases - physiology | Multiprotein Complexes - physiology | Protein Interaction Mapping | Sequence Homology, Amino Acid | Transcription Factors, General - physiology | Multiprotein Complexes - chemistry | Sequence Alignment | Animals | Endopeptidases - genetics | Heterochromatin - genetics | Receptors, Androgen - genetics | Drosophila Proteins - genetics | Thiolester Hydrolases - chemistry | Transcription, Genetic - genetics | Endopeptidases - physiology | Histones | Index Medicus | p300-CBP Transcription Factors | Histone Acetyltransferases | Multiprotein Complexes | Receptors, Androgen | Recombinant Fusion Proteins | Life Sciences | Ubiquitination | Heterochromatin | Transcription, Genetic | Promoter Regions (Genetics) | Drosophila Proteins | Transcription Factors, General | Trans-Activators | Biochemistry, Molecular Biology | Thiolester Hydrolases | Transcription Factors | RNA Polymerase II | Drosophila melanogaster | Endopeptidases
Journal Article
Science, ISSN 0036-8075, 05/2017, Volume 356, Issue 6337, pp. eaaj2239 - eaaj2239
Journal Article
Nature, ISSN 0028-0836, 11/2009, Volume 462, Issue 7270, pp. 182 - 188
Direct inhibition of transcription factor complexes remains a central challenge in the discipline of ligand discovery. In general, these proteins lack surface... 
PROGENITOR CELLS | ACTIVATION | GENE | MULTIDISCIPLINARY SCIENCES | ACUTE LYMPHOBLASTIC-LEUKEMIA | T-CELL LEUKEMIA | C-MYC | GAMMA-SECRETASE INHIBITORS | MUTATIONS | HUMAN HOMOLOG | MASTERMIND | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Transcription Factors - chemistry | Humans | Transcriptional Activation - drug effects | Genome - genetics | Receptor, Notch1 - chemistry | Cell Membrane Permeability | Substrate Specificity | DNA-Binding Proteins - metabolism | Peptides - chemical synthesis | Peptides - metabolism | Protein Binding - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Disease Models, Animal | Binding, Competitive | Protein Structure, Tertiary | Immunoglobulin J Recombination Signal Sequence-Binding Protein - metabolism | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Peptides - chemistry | Protein Structure, Secondary | Models, Molecular | Drosophila Proteins - chemistry | Receptor, Notch1 - metabolism | Genome - drug effects | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | Peptides - pharmacology | Transcription Factors - metabolism | Animals | Signal Transduction - drug effects | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Receptor, Notch1 - antagonists & inhibitors | Transcription factors | Research | Ligands (Biochemistry) | Peptide bonds | Index Medicus
Journal Article
Structure, ISSN 0969-2126, 10/2015, Volume 23, Issue 10, pp. 1801 - 1814
Bromodomains are epigenetic readers that are recruited to acetyllysine residues in histone tails. Recent studies have identified non-acetyl acyllysine... 
EPIGENETIC READERS | INTERMEDIARY METABOLISM | SUCCINYLATION | ACETYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | POSTTRANSLATIONAL MODIFICATIONS | CELL BIOLOGY | CIRCADIAN CLOCK | BIOPHYSICS | SMALL-MOLECULE INHIBITORS | LYSINE PROPIONYLATION | PROTEINS | ACETYLOME | TATA-Binding Protein Associated Factors - metabolism | Transcription Factor TFIID - chemistry | Butyrates - metabolism | Transcription Factors - chemistry | Crotonates - metabolism | Histone Acetyltransferases - chemistry | Histones - chemistry | Epigenesis, Genetic | Humans | Histone Acetyltransferases - genetics | Crystallography, X-Ray | Transcription Factor TFIID - metabolism | Transcription Factor TFIID - genetics | Histone Acetyltransferases - metabolism | Escherichia coli - metabolism | Water - chemistry | Lysine - metabolism | Binding Sites | Acylation | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Crotonates - chemistry | Gene Expression | Protein Structure, Secondary | Water - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | TATA-Binding Protein Associated Factors - chemistry | Transcription Factors - genetics | TATA-Binding Protein Associated Factors - genetics | Transcription Factors - metabolism | Histones - genetics | Escherichia coli - genetics | Butyrates - chemistry | Protein Array Analysis | Protein Binding | Protein Processing, Post-Translational | Histones - metabolism | Kinetics | Lysine - chemistry | Peptides | Epigenetic inheritance | Index Medicus
Journal Article
Science, ISSN 0036-8075, 6/2009, Volume 324, Issue 5935, pp. 1720 - 1723
Journal Article