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Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2014, Volume 111, Issue 34, pp. 12426 - 12431
Pluripotency can be induced in somatic cells by overexpressing transcription factors, including POU class 5 homeobox 1 (OCT3/4... 
Phenotypes | Induced pluripotent stem cells | Somatic cells | Stem cells | Retroviridae | Embryonic stem cells | Pluripotent stem cells | Cellular differentiation | Cells | Mesenchymal stem cells | Epigenetics | Retrotransposon | Evolution | NONCODING RNA-ROR | ROADBLOCK | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | TRANSPOSABLE ELEMENTS | evolution | INDUCTION | epigenetics | IPS CELLS | PLURIPOTENT STEM-CELLS | PATHWAY | HUMAN FIBROBLASTS | retrotransposon | EXPRESSION | Octamer Transcription Factor-3 - physiology | Endogenous Retroviruses - physiology | Embryonic Stem Cells - cytology | Epigenesis, Genetic | Humans | Endogenous Retroviruses - genetics | Pluripotent Stem Cells - virology | Gene Knockdown Techniques | Octamer Transcription Factor-3 - genetics | Cell Differentiation - genetics | RNA, Viral - antagonists & inhibitors | RNA, Viral - genetics | SOXB1 Transcription Factors - genetics | Embryonic Stem Cells - virology | SOXB1 Transcription Factors - physiology | Induced Pluripotent Stem Cells - cytology | Cell Differentiation - physiology | Cellular Reprogramming - genetics | Gene Expression | Pluripotent Stem Cells - cytology | Induced Pluripotent Stem Cells - physiology | Induced Pluripotent Stem Cells - virology | Pluripotent Stem Cells - physiology | Kruppel-Like Transcription Factors - physiology | RNA, Long Noncoding - genetics | Embryonic Stem Cells - physiology | RNA, Long Noncoding - antagonists & inhibitors | Kruppel-Like Transcription Factors - genetics | Cellular Reprogramming - physiology | Epigenetic inheritance | Transcription factors | Retroviruses | Physiological aspects | Genetic research | Genetic aspects | Research | Cell differentiation | Gene expression | Virus research | Biological Sciences
Journal Article
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2012, Volume 148, Issue 3, pp. 399 - 408
Journal Article
Cerebral cortex (New York, N.Y. 1991), ISSN 1460-2199, 2014, Volume 24, Issue 1, pp. 186 - 198
Journal Article
Seminars in Cell and Developmental Biology, ISSN 1084-9521, 2007, Volume 18, Issue 1, pp. 117 - 131
Journal Article
Nature reviews. Cancer, ISSN 1474-1768, 2002, Volume 2, Issue 1, pp. 38 - 47
Cells undergo a variety of biological responses when placed in hypoxic conditions, including activation of signalling pathways that regulate proliferation,... 
TARGET GENES | ACTIVATED PROTEIN-KINASE | P53-DEPENDENT APOPTOSIS | ONCOLOGY | INDUCIBLE FACTOR 1-ALPHA | GENE-EXPRESSION | BINDING-PROTEIN | FACTOR-I | FACTORS HIF-1-ALPHA | FACTOR (HIF)-1-ALPHA | UP-REGULATION | Oxidative Stress | Vascular Endothelial Growth Factors | Humans | Hypoxia-Inducible Factor 1, alpha Subunit | Trans-Activators - physiology | Aryl Hydrocarbon Receptor Nuclear Translocator | Antineoplastic Agents - pharmacokinetics | Dimerization | Basic Helix-Loop-Helix Transcription Factors | Endothelial Growth Factors - physiology | DNA-Binding Proteins - physiology | Hypoxia-Inducible Factor 1 | Oxidation-Reduction | Signal Transduction | Lymphokines - physiology | Neoplasms - blood supply | Forecasting | Trans-Activators - deficiency | Mice | Neovascularization, Pathologic - metabolism | DNA Damage | Hydrogen-Ion Concentration | Neoplasms - metabolism | Vascular Endothelial Growth Factor A | Erythropoietin - therapeutic use | Receptor Protein-Tyrosine Kinases - physiology | Transcription Factors - deficiency | Embryonic and Fetal Development | Oxygen - metabolism | Vascular Endothelial Growth Factor Receptor-1 | Cell Hypoxia | Neoplasms - genetics | Cell Division | Trans-Activators - genetics | Transcription Factors - physiology | Cell Survival | Gene Expression Regulation | Transcription Factors - genetics | Cyclic AMP Response Element-Binding Protein - physiology | Xenograft Model Antitumor Assays | Animals | Prodrugs - pharmacokinetics | NF-kappa B - physiology | Proto-Oncogene Proteins - physiology | Glycolysis | Neovascularization, Pathologic - genetics | Nuclear Proteins - physiology | Neoplasms - pathology | Receptors, Aryl Hydrocarbon | Apoptosis | Complications and side effects | Care and treatment | Prognosis | Growth | Physiological aspects | Hypoxia | Research | Tumors
Journal Article