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by Djebali, Sarah and Davis, Carrie A and Merkel, Angelika and Dobin, Alex and Lassmann, Timo and Mortazavi, Ali and Tanzer, Andrea and Lagarde, Julien and Lin, Wei and Schlesinger, Felix and Xue, Chenghai and Marinov, Georgi K and Khatun, Jainab and Williams, Brian A and Zaleski, Chris and Rozowsky, Joel and Röder, Maik and Kokocinski, Felix and Abdelhamid, Rehab F and Alioto, Tyler and Antoshechkin, Igor and Baer, Michael T and Bar, Nadav S and Batut, Philippe and Bell, Kimberly and Bell, Ian and Chakrabortty, Sudipto and Chen, Xian and Chrast, Jacqueline and Curado, Joao and Derrien, Thomas and Drenkow, Jorg and Dumais, Erica and Dumais, Jacqueline and Duttagupta, Radha and Falconnet, Emilie and Fastuca, Meagan and Fejes-Toth, Kata and Ferreira, Pedro and Foissac, Sylvain and Fullwood, Melissa J and Gao, Hui and Gonzalez, David and Gordon, Assaf and Gunawardena, Harsha and Howald, Cedric and Jha, Sonali and Johnson, Rory and Kapranov, Philipp and King, Brandon and Kingswood, Colin and Luo, Oscar J and Park, Eddie and Persaud, Kimberly and Preall, Jonathan B and Ribeca, Paolo and Risk, Brian and Robyr, Daniel and Sammeth, Michael and Schaffer, Lorian and See, Lei-Hoon and Shahab, Atif and Skancke, Jorgen and Suzuki, Ana Maria and Takahashi, Hazuki and Tilgner, Hagen and Trout, Diane and Walters, Nathalie and Wang, Huaien and Wrobel, John and Yu, Yanbao and Ruan, Xiaoan and Hayashizaki, Yoshihide and Harrow, Jennifer and Gerstein, Mark and Hubbard, Tim and Reymond, Alexandre and Antonarakis, Stylianos E and Hannon, Gregory and Giddings, Morgan C and Ruan, Yijun and Wold, Barbara and Carninci, Piero and Guigó, Roderic and Gingeras, Thomas R
Nature (London), ISSN 1476-4687, 2012, Volume 489, Issue 7414, pp. 101 - 108
Journal Article
Nature (London), ISSN 1476-4687, 2013, Volume 506, Issue 7488, pp. 371 - 375
Cervical cancer is responsible for 10-15% of cancer-related deaths in women worldwide(1,2). The aetiological role of infection with high-risk human papilloma... 
DOMAIN | CATALOG | FUSION | MULTIDISCIPLINARY SCIENCES | FRAMEWORK | HUMAN-PAPILLOMAVIRUS | SENSITIVE DETECTION | CANCER | EXPRESSION | SOMATIC MUTATIONS | DISCOVERY | F-Box-WD Repeat-Containing Protein 7 | Receptor, ErbB-2 - genetics | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - virology | Genomics | Humans | E1A-Associated p300 Protein - genetics | Core Binding Factor beta Subunit - genetics | Case-Control Studies | Papillomaviridae - genetics | Tumor Suppressor Protein p53 - genetics | DNA Mutational Analysis | Mitogen-Activated Protein Kinase 1 - genetics | Cell Cycle Proteins - genetics | Female | NF-E2-Related Factor 2 - genetics | Adenocarcinoma - genetics | Papillomaviridae - physiology | HLA-B Antigens - genetics | Gene Expression Regulation, Neoplastic - genetics | Proto-Oncogene Proteins c-ets | Virus Integration - genetics | Proto-Oncogene Proteins - genetics | DNA Copy Number Variations - genetics | Transcriptome - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Uterine Cervical Neoplasms - genetics | Adenocarcinoma - virology | Genome, Human - genetics | Papillomavirus Infections - genetics | Exome - genetics | Uterine Cervical Neoplasms - virology | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Prevention | Gene mutations | Oncology, Experimental | Exome sequencing | Genetic aspects | Research | Cervical cancer | Cancer | Human papillomavirus | Mutation
Journal Article
Nature Communications, ISSN 2041-1723, 07/2015, Volume 6, Issue 1, p. 7557
...) and DNA methylome analyses to unravel the genetic/epigenetic basis of RMS. On the basis of methylation patterns, RMS is clustered into four distinct subtypes... 
WIDE DNA METHYLATION | AMPLIFICATION | PIK3CA GENE | EMBRYONAL RHABDOMYOSARCOMA | PATHWAY MUTATIONS | ADOLESCENTS | MULTIDISCIPLINARY SCIENCES | PTEN | ALVEOLAR RHABDOMYOSARCOMA | HUMAN CANCER | BREAST | Paired Box Transcription Factors - genetics | F-Box-WD Repeat-Containing Protein 7 | ras Proteins - genetics | Prognosis | Rhabdomyosarcoma, Embryonal - classification | Humans | Transcriptome | Child, Preschool | PAX7 Transcription Factor - genetics | Infant | Male | Rhabdomyosarcoma, Alveolar - classification | RNA, Messenger - metabolism | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | Exome | Rhabdomyosarcoma, Embryonal - genetics | Young Adult | Cell Cycle Proteins - genetics | Female | Receptor, Fibroblast Growth Factor, Type 4 - genetics | Child | Gene Expression Regulation, Neoplastic - genetics | PTEN Phosphohydrolase - genetics | PAX3 Transcription Factor | Rhabdomyosarcoma, Alveolar - genetics | Repressor Proteins - genetics | Proto-Oncogene Proteins - genetics | DNA Methylation - genetics | Forkhead Transcription Factors - genetics | beta Catenin - genetics | Epigenesis, Genetic - genetics | Adolescent | Rhabdomyosarcoma - classification | Forkhead Box Protein O1 | Rhabdomyosarcoma - genetics | Mutation | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics
Journal Article
Nature (London), ISSN 1476-4687, 2014, Volume 513, Issue 7518, pp. 382 - 387
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 1945-7197, 2017, Volume 102, Issue 8, pp. 3029 - 3039
Context: Only a few genetic causes for childhood obesity have been identified to date... 
ENDOCRINOLOGY & METABOLISM | FAT | LOCI | MUTATIONS | REARRANGEMENTS | ASSOCIATION | DELETIONS | TYPE-2 | CONTRIBUTES | INSIGHTS | Hydrolases - genetics | Humans | DNA Repair Enzymes - genetics | Transcriptome | Child, Preschool | Male | Chromosome Duplication - genetics | RNA, Messenger - metabolism | Autoantigens - genetics | Case-Control Studies | DNA Copy Number Variations | Intellectual Disability - genetics | Young Adult | Chromosomes, Human, Pair 22 - genetics | Subcutaneous Fat - metabolism | Cell Cycle Proteins - genetics | Adult | Female | Chromosomes, Human, Pair 1 - genetics | Nuclear Proteins - genetics | Child | Microfilament Proteins - genetics | Abnormalities, Multiple - genetics | DiGeorge Syndrome - genetics | Chromosomes, Human, Pair 16 - genetics | Siblings | Autistic Disorder - genetics | Chromosome Deletion | Megalencephaly - genetics | Extracellular Matrix Proteins - genetics | Pediatric Obesity - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Proteins - genetics | Comparative Genomic Hybridization | Adolescent | Ataxia Telangiectasia Mutated Proteins - genetics | Kruppel-Like Transcription Factors - genetics | Acid Phosphatase - genetics | Chromosome Disorders - genetics | Obesity | Adipose tissue | Prader-Willi syndrome | Copy number | Genes | mRNA | Hybridization | Gene expression | Ribonucleic acid--RNA | Body mass index | DNA microarrays | Pathways | Clonal deletion | Body mass | Body size | Children | Age | deletions | insights | bardet-biedl-syndrome | association | Klinisk medicin | contributes | population | type-2 | Clinical Medicine | mutations | rearrangements | Endocrinology & Metabolism | loci
Journal Article
by Curtis, Bruce A and Tanifuji, Goro and Burki, Fabien and Gruber, Ansgar and Irimia, Manuel and Maruyama, Shinichiro and Arias, Maria C and Ball, Steven G and Gile, Gillian H and Hirakawa, Yoshihisa and Hopkins, Julia F and Kuo, Alan and Rensing, Stefan A and Schmutz, Jeremy and Symeonidi, Aikaterini and Elias, Marek and Eveleigh, Robert J. M and Herman, Emily K and Klute, Mary J and Nakayama, Takuro and Oborník, Miroslav and Reyes-Prieto, Adrian and Armbrust, E. Virginia and Aves, Stephen J and Beiko, Robert G and Coutinho, Pedro and Dacks, Joel B and Durnford, Dion G and Fast, Naomi M and Green, Beverley R and Grisdale, Cameron J and Hempel, Franziska and Henrissat, Bernard and Höppner, Marc P and Ishida, Ken-Ichiro and Kim, Eunsoo and Kořený, Luděk and Kroth, Peter G and Liu, Yuan and Malik, Shehre-Banoo and Maier, Uwe G and McRose, Darcy and Mock, Thomas and Neilson, Jonathan A. D and Onodera, Naoko T and Poole, Anthony M and Pritham, Ellen J and Richards, Thomas A and Rocap, Gabrielle and Roy, Scott W and Sarai, Chihiro and Schaack, Sarah and Shirato, Shu and Slamovits, Claudio H and Spencer, David F and Suzuki, Shigekatsu and Worden, Alexandra Z and Zauner, Stefan and Barry, Kerrie and Bell, Callum and Bharti, Arvind K and Crow, John A and Grimwood, Jane and Kramer, Robin and Lindquist, Erika and Lucas, Susan and Salamov, Asaf and McFadden, Geoffrey I and Lane, Christopher E and Keeling, Patrick J and Gray, Michael W and Grigoriev, Igor V and Archibald, John M and Joint Genome Institute (JGI)
Nature (London), ISSN 1476-4687, 2012, Volume 492, Issue 7427, pp. 59 - 65
... pathogen Plasmodium (3). We have sequenced the nuclear genomes of two unicellular algae that are remarkable in their genetic and cellular complexity: the cryptophyte... 
EUKARYOTIC GENOMES | ORIGIN | NUCLEUS | MULTIDISCIPLINARY SCIENCES | SEQUENCE | BIGELOWIELLA-NATANS | GUILLARDIA-THETA | GENE-TRANSFER | CHLORARACHNIOPHYTE | PROTEINS | CRYPTOPHYTES | Physiological aspects | Mosaicism | Genetic aspects | Research | Photosynthesis | Cryptomonads | Risk factors | Algae | Genomes | Identification and classification | Natural history | Proteins | Plankton | Genes | Cyclin-dependent kinases | Genetics | Plastids
Journal Article
PLoS Pathogens, ISSN 1553-7366, 05/2011, Volume 7, Issue 5, p. e1002027
During infection Neisseria meningitidis (Nm) encounters multiple environments within the host, which makes rapid adaptation a crucial factor for meningococcal... 
FACTOR-H-BINDING | MICROBIOLOGY | BACTERIAL | GENOME | PATHOGENIC NEISSERIAE | VACCINE CANDIDATES | VIROLOGY | OUTER-MEMBRANE PROTEIN | GENE-EXPRESSION | STAPHYLOCOCCUS-AUREUS | SERINE-PROTEASE | GROUP-B | PARASITOLOGY | Adaptation, Physiological | Sequence Deletion | Virulence Factors - genetics | Genes, Bacterial - genetics | Humans | Neisseria meningitidis, Serogroup B - physiology | Transcriptome | Male | Neisseria meningitidis, Serogroup B - genetics | Meningococcal Infections - microbiology | Antigens, Bacterial - genetics | Bacteremia - microbiology | Bacteremia - blood | RNA, Bacterial - genetics | Adult | Female | Neisseria meningitidis, Serogroup B - pathogenicity | Bacterial Proteins - genetics | Up-Regulation - genetics | Down-Regulation - genetics | Neisseria meningitidis, Serogroup B - growth & development | Genome, Bacterial - genetics | Gene Expression Regulation, Bacterial - genetics | Host-Pathogen Interactions - genetics | Models, Biological | Meningococcal Infections - blood | Cluster Analysis | Causes of | Sepsis | Neisseria meningitidis | Genetic aspects | Research | Health aspects | Microbiology | Pathogenesis | Mortality | Genomes | Gene expression | Blood | Proteins | Studies | Evolutionary biology | Mutagenesis | DNA methylation | Meningitis | Deoxyribonucleic acid--DNA | Deoxyribonucleic acid | DNA
Journal Article
Nature (London), ISSN 1476-4687, 2013, Volume 500, Issue 7463, pp. 422 - 426
Journal Article