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Nature medicine, ISSN 1546-170X, 01/2017, Volume 23, Issue 2, pp. 174 - 184
Low-grade, chronic inflammation has been associated with many diseases of aging, but the mechanisms responsible for producing this inflammation remain unclear.... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Toll-Like Receptor 5 - genetics | Humans | Middle Aged | Oxidative Stress - immunology | Transcriptome | Immunoblotting | Male | Purinergic P1 Receptor Antagonists - pharmacology | Young Adult | Toll-Like Receptor 8 - immunology | Aging - immunology | Toll-Like Receptor 6 - immunology | Aging - genetics | Calcium-Binding Proteins - immunology | Interleukin-1beta - metabolism | Aged, 80 and over | Caffeine - pharmacology | Hypertension - genetics | Intracellular Signaling Peptides and Proteins - genetics | Interleukin 1 Receptor Antagonist Protein - immunology | Carotid Intima-Media Thickness | Mortality | Neutrophils - drug effects | Hypertension - immunology | Nucleotides - metabolism | Toll-Like Receptor 5 - immunology | Monocytes - drug effects | Regression Analysis | Phenotype | Mice | Calcium-Binding Proteins - genetics | Metabolomics | Pulse Wave Analysis | Neutrophil Activation - drug effects | Cytidine - pharmacology | Interleukin 1 Receptor Antagonist Protein - genetics | Intracellular Signaling Peptides and Proteins - immunology | Cytidine - analogs & derivatives | CARD Signaling Adaptor Proteins - genetics | Toll-Like Receptor 6 - genetics | Adult | Female | Blood Pressure - drug effects | Blood Platelets - drug effects | Macrophages - immunology | Cytokines - immunology | CARD Signaling Adaptor Proteins - immunology | Cell Line | Vascular Stiffness - genetics | Cytokines - metabolism | Oxidative Stress - genetics | Interleukin-1beta - immunology | Adenine - pharmacology | Inflammation - immunology | Inflammasomes - genetics | Vascular Stiffness - immunology | Animals | Inflammasomes - immunology | Toll-Like Receptor 8 - genetics | Inflammation - genetics | Aged | Platelet Activation - drug effects | Genetic aspects | Immune response | Gene expression | Health aspects | Aging | Inflammation | Immune system | Index Medicus
Journal Article
Nature immunology, ISSN 1529-2916, 08/2014, Volume 15, Issue 10, pp. 938 - 946
We examined the role of innate cells in acquired resistance to the natural murine parasitic nematode, Nippostrongylus brasiliensis. Macrophages obtained from... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Oligonucleotide Array Sequence Analysis | Strongylida Infections - genetics | Interleukin-13 - immunology | Disease Resistance - immunology | Transcriptome - immunology | Nippostrongylus - immunology | Interleukin-4 Receptor alpha Subunit - genetics | Interleukin-13 - genetics | Flow Cytometry | Larva - immunology | Strongylida Infections - parasitology | Strongylida Infections - immunology | Female | Lung - metabolism | Adaptive Immunity - immunology | Cytokines - genetics | Neutrophils - metabolism | Macrophages - immunology | Cytokines - immunology | Interleukin-4 Receptor alpha Subunit - metabolism | Cytokines - metabolism | Lung - parasitology | Cells, Cultured | Neutrophils - immunology | Host-Parasite Interactions - immunology | Interleukin-13 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-4 Receptor alpha Subunit - immunology | Mice, Knockout | Cell Adhesion - immunology | Macrophages - metabolism | Animals | Nippostrongylus - physiology | Cell Adhesion - physiology | Mice, Inbred BALB C | Larva - physiology | Lung - immunology | Host-parasite relationships | Genetic aspects | Immune response | Properties | Macrophages | Neutrophils | Index Medicus | Parasite | macrophage | type 2 response | helminth | neutrophil | TH2 cytokines
Journal Article
Nature immunology, ISSN 1529-2916, 10/2013, Volume 14, Issue 12, pp. 1294 - 1301
Tissue-resident memory T cells (TRM cells) provide superior protection against infection in extralymphoid tissues. Here we found that CD103(+)CD8(+) TRM cells... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Receptors, Transforming Growth Factor beta - genetics | Receptors, Transforming Growth Factor beta - immunology | Oligonucleotide Array Sequence Analysis | Skin - metabolism | Antigens, CD - genetics | Antigens, CD - metabolism | Host-Pathogen Interactions - immunology | Lectins, C-Type - metabolism | Herpesvirus 1, Human - physiology | Integrin alpha Chains - immunology | CD8-Positive T-Lymphocytes - metabolism | Protein-Serine-Threonine Kinases - metabolism | Antigens, Differentiation, T-Lymphocyte - metabolism | Mice, Transgenic | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Herpes Simplex - immunology | Mice, Knockout | Cell Differentiation - immunology | Herpes Simplex - virology | Interleukin-15 - metabolism | Mice | CD8-Positive T-Lymphocytes - immunology | Receptors, Immunologic - genetics | Antigens, CD - immunology | Lectins, C-Type - immunology | Transcriptome - immunology | Lectins, C-Type - genetics | Interleukin-15 - immunology | Cell Differentiation - genetics | Signal Transduction - immunology | Flow Cytometry | Herpesvirus 1, Human - immunology | Receptors, Immunologic - immunology | Skin - virology | Immunologic Memory - immunology | Skin - immunology | Antigens, Differentiation, T-Lymphocyte - immunology | Mice, Inbred C57BL | Protein-Serine-Threonine Kinases - genetics | Integrin alpha Chains - metabolism | Transcriptome - genetics | Mice, Inbred Strains | Animals | Interleukin-15 - genetics | Receptors, Transforming Growth Factor beta - metabolism | CD8-Positive T-Lymphocytes - virology | Antigens, Differentiation, T-Lymphocyte - genetics | Protein-Serine-Threonine Kinases - immunology | Integrin alpha Chains - genetics | Receptors, Immunologic - metabolism | Index Medicus
Journal Article
Nature immunology, ISSN 1529-2916, 12/2015, Volume 16, Issue 12, pp. 1235 - 1244
Ectopic lymphoid-like structures (ELSs) are often observed in cancer, yet their function is obscure. Although ELSs signify good prognosis in certain... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Stem Cell Niche - immunology | Humans | Immunity, Innate - genetics | NF-kappa B - immunology | Neoplastic Stem Cells - immunology | Hepatocytes - pathology | Immunoblotting | NF-kappa B - metabolism | Transcriptome - immunology | Hepatocytes - metabolism | Adaptive Immunity - genetics | Lymphoid Tissue - immunology | In Situ Hybridization | I-kappa B Kinase - metabolism | Neoplastic Stem Cells - metabolism | T-Lymphocytes - metabolism | Carcinoma, Hepatocellular - genetics | Carcinoma, Hepatocellular - immunology | Adaptive Immunity - immunology | Cytokines - genetics | Stem Cell Niche - genetics | Cytokines - immunology | Disease Models, Animal | Cytokines - metabolism | Liver Neoplasms - genetics | Mice, Inbred C57BL | Lymphoid Tissue - metabolism | Liver Neoplasms - immunology | Mice, Transgenic | Transcriptome - genetics | I-kappa B Kinase - genetics | Hepatocytes - immunology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Immunity, Innate - immunology | Lymphoid Tissue - pathology | Animals | Comparative Genomic Hybridization | NF-kappa B - genetics | Liver Neoplasms - metabolism | I-kappa B Kinase - immunology | T-Lymphocytes - immunology | Carcinoma, Hepatocellular - metabolism | Molecular targeted therapy | Transcription factors | Oncology, Experimental | Genetic research | Development and progression | Genetic aspects | Hepatoma | Research | Health aspects | Methods | Cancer | Medical colleges | Prognosis | Cytokines | Analysis | Liver | Inflammation | B cells | T cells | Index Medicus
Journal Article
The journal of clinical endocrinology and metabolism, ISSN 1945-7197, 05/2017, Volume 102, Issue 5, pp. 1468 - 1477
Context: Increasing evidences suggest a correlation between gut and type 1 diabetes (T1D). Objective: The objective of this study is to evaluate the gut... 
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Receptors, CCR2 - genetics | Serum Amyloid P-Component - immunology | Receptors, CCR2 - immunology | Humans | Middle Aged | Tumor Necrosis Factor-alpha - genetics | Transcriptome | Child, Preschool | Male | Monocyte Chemoattractant Proteins - immunology | Vascular Endothelial Growth Factor A - genetics | Antigens, CD - genetics | Interleukin-4 Receptor alpha Subunit - genetics | Young Adult | Celiac Disease - microbiology | Cyclooxygenase 2 - genetics | Intestinal Mucosa - immunology | Diabetes Mellitus, Type 1 - microbiology | Tumor Necrosis Factor-alpha - immunology | Child | Real-Time Polymerase Chain Reaction | Duodenum - immunology | Vascular Endothelial Growth Factor A - immunology | C-Reactive Protein - genetics | Intestinal Mucosa - microbiology | Reverse Transcriptase Polymerase Chain Reaction | Monocyte Chemoattractant Proteins - genetics | Chemokine CCL22 - genetics | Chemokine CCL19 - genetics | Adolescent | RNA, Ribosomal, 16S - genetics | C-Reactive Protein - immunology | Antigens, CD - immunology | Infant | Case-Control Studies | Duodenum - microbiology | Chemokine CCL22 - immunology | Celiac Disease - immunology | Adult | Female | Diabetes Mellitus, Type 1 - immunology | Chemokine CCL19 - immunology | Cyclooxygenase 2 - immunology | Antigens, Differentiation, Myelomonocytic - immunology | Diabetes Mellitus, Type 1 - genetics | Gastrointestinal Microbiome - genetics | Interleukin-4 Receptor alpha Subunit - immunology | Antigens, Differentiation, Myelomonocytic - genetics | Serum Amyloid P-Component - genetics | Aged | Immunohistochemistry | CC chemokine receptors | rRNA 16S | CCL19 protein | Pathogenesis | Mucosa | Microbiomes | Diabetes mellitus (insulin dependent) | Macrophages | Small intestine | Gene sequencing | CCL22 protein | Microbiota | CCR2 protein | Intestine | Interleukin 4 receptors | Digestive tract | Duodenum | Digestive system | Abnormalities | Diabetes mellitus | Inflammation | Tumor necrosis factor-α | Gene expression | Ribonucleic acid--RNA | Disease control | Patients | Celiac disease | Biopsy | Infiltration | Diabetes | Cyclooxygenase-2 | Autoimmune diseases | Monocyte chemoattractant protein 1 | Index Medicus | Abridged Index Medicus
Journal Article
Hypertension (Dallas, Tex. 1979), ISSN 0194-911X, 2014, Volume 63, Issue 6, pp. 1241 - 1250
Connective tissue growth factor (CTGF) is involved in the pathogenesis of various fibrotic disorders. However, its role in the heart is not clear. To... 
Hypertension | Inflammation | S100 proteins | Angiotensin II | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Immunohistochemistry | Calgranulin B - metabolism | Oligonucleotide Array Sequence Analysis | Myocytes, Cardiac - immunology | Calgranulin A - genetics | Inflammation - metabolism | Myocardium - metabolism | Antibodies - immunology | Antigens, Ly - metabolism | Calgranulin A - immunology | Hypertension - genetics | Cytokines - genetics | Neutrophils - metabolism | Receptor for Advanced Glycation End Products | Fibroblasts - metabolism | Animals, Newborn | Angiotensin II - pharmacology | Neutrophils - drug effects | Toll-Like Receptor 4 - genetics | Hypertension - immunology | Toll-Like Receptor 4 - immunology | Reverse Transcriptase Polymerase Chain Reaction | Toll-Like Receptor 4 - metabolism | Myocytes, Cardiac - drug effects | Fibroblasts - drug effects | Myocytes, Cardiac - metabolism | Fibroblasts - immunology | Mice | Receptors, Immunologic - genetics | Myocardium - immunology | Calgranulin A - metabolism | Transcriptome - immunology | Calgranulin B - immunology | Hypertension - prevention & control | Calgranulin B - genetics | Receptors, Immunologic - immunology | Cytokines - immunology | CD11b Antigen - immunology | Cytokines - metabolism | Mice, Inbred C57BL | Cells, Cultured | Neutrophils - immunology | Myocardium - pathology | Inflammation - immunology | Transcriptome - drug effects | Angiotensin II - immunology | Antibodies - pharmacology | Animals | Antigens, Ly - immunology | Inflammation - genetics | CD11b Antigen - metabolism | Receptors, Immunologic - metabolism | Index Medicus
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 11/2015, Volume 212, Issue 12, pp. 2041 - 2056
Journal Article
Molecular immunology, ISSN 0161-5890, 12/2013, Volume 56, Issue 4, pp. 317 - 327
Journal Article