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ChemBioChem, ISSN 1439-4227, 05/2014, Volume 15, Issue 8, pp. 1200 - 1209
Journal Article
Nucleic acids research, ISSN 0305-1048, 08/2017, Volume 45, Issue 14, pp. e133 - e133
Journal Article
RNA Biology, ISSN 1547-6286, 05/2018, Volume 15, Issue 4-5, pp. 667 - 677
Inhibition of tRNA aminoacylation has proven to be an effective antimicrobial strategy, impeding an essential step of protein synthesis. Mupirocin, the... 
Aminoacylation | transfer RNA | translation inhibitors | drug development | drug targets | antibiotic targets | antimicrobials | aminoacyl tRNA synthetases | antibiotics | ACCEPTOR IN-VITRO | DISCRIMINATOR BASE | RIBONUCLEASE-P RIBOZYME | IDENTITY DETERMINANTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SYNTHETASE INHIBITORS | GENETIC-CODE | CONFORMATIONAL-CHANGES | PROTEIN-PROTEIN INTERACTIONS | SPECIES-SPECIFIC AMINOACYLATION | THERMUS-THERMOPHILUS | Thermus thermophilus - drug effects | Protein Synthesis Inhibitors - chemistry | Species Specificity | Escherichia coli - drug effects | Humans | Structure-Activity Relationship | Fatty Alcohols - chemistry | Fatty Alcohols - pharmacology | Thermus thermophilus - genetics | RNA, Transfer, Leu - metabolism | Isoleucine-tRNA Ligase - genetics | Piperidines - pharmacology | Anti-Bacterial Agents - chemistry | Protein Synthesis Inhibitors - pharmacology | Quinazolinones - pharmacology | RNA, Transfer, Leu - genetics | Thermus thermophilus - enzymology | Piperidines - chemistry | Escherichia coli - enzymology | Transfer RNA Aminoacylation - genetics | Mupirocin - pharmacology | Mupirocin - chemistry | Isoleucine-tRNA Ligase - metabolism | Escherichia coli - genetics | RNA, Transfer, Leu - antagonists & inhibitors | Anti-Bacterial Agents - pharmacology | Quinazolinones - chemistry | Transfer RNA Aminoacylation - drug effects | Isoleucine-tRNA Ligase - antagonists & inhibitors | Biochemistry & Molecular Biology
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 04/2018, Volume 46, Issue 7, pp. 3643 - 3656
Journal Article
Journal Article