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Science, ISSN 0036-8075, 05/2016, Volume 352, Issue 6288, pp. 986 - 990
Phosphorus is a macronutrient taken up by cells as inorganic phosphate ([P.sub.i]). How cells sense cellular [P.sub.i] levels is poorly characterized. Here, we... 
Eukaryotes | Ligands (Biochemistry) | Homeostasis | Physiological aspects | Cellular signal transduction | Properties | Observations | Phosphates | Proteins | Transcription factors
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 07/2013, Volume 49, Issue 1, pp. 6 - 17
Acute lung injury (ALI) attributable to sepsis or mechanical ventilation and subacute lung injury because of ionizing radiation (RILI) share profound increases... 
S1P lyase | Sepsis | Sphingosine kinase | Sphingolipids | S1P receptors | sphingolipids | PROTEASOMAL DEGRADATION | sphingosine kinase | BIOCHEMISTRY & MOLECULAR BIOLOGY | FINGOLIMOD FTY720 | SPHINGOSINE 1-PHOSPHATE | CELL BIOLOGY | SMOOTH-MUSCLE | IN-VITRO | PROTEIN-COUPLED RECEPTOR | RESPIRATORY SYSTEM | VASCULAR LEAK | BARRIER ENHANCEMENT | GROWTH-FACTOR | sepsis | DRUG FTY720 | Lysophospholipids - metabolism | Capillary Permeability | Transferases (Other Substituted Phosphate Groups) - genetics | Humans | Pneumonia - pathology | Transferases (Other Substituted Phosphate Groups) - metabolism | Sepsis - pathology | Sepsis - metabolism | Propylene Glycols - therapeutic use | Anti-Inflammatory Agents - therapeutic use | Acute Lung Injury - drug therapy | Membrane Proteins - metabolism | Sphingosine - metabolism | Receptors, Lysosphingolipid - metabolism | Biomarkers - metabolism | Acute Lung Injury - physiopathology | Membrane Proteins - genetics | Translational Medical Research | Fingolimod Hydrochloride | Phosphotransferases (Alcohol Group Acceptor) - genetics | Lung - physiopathology | Nerve Tissue Proteins - genetics | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Nerve Tissue Proteins - metabolism | Sphingosine - analogs & derivatives | Animals | Sphingosine - therapeutic use | Lung - blood supply | Pneumonia - metabolism | Translational Review
Journal Article
Nature Neuroscience, ISSN 1097-6256, 10/2012, Volume 15, Issue 10, pp. 1407 - 1413
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2013, Volume 110, Issue 5, pp. 1827 - 1832
CD1d-restricted natural killer T (NKT) cells include two major subgroups. The most widely studied are Vα14Jα18⁺ invariant NKT (iNKT) cells that recognize the... 
T lymphocytes | Antigens | Reactivity | Natural killer T cells | Hybridomas | Antigen presenting cells | Lipids | Infections | Phospholipids | T cell antigen receptors | CD1 antigen presentation | Innate immunity | Adaptive immunity | Type II natural killer T cell | SULFATIDE | REPERTOIRE | POPULATION | ACTIVATION | MULTIDISCIPLINARY SCIENCES | DISTINCT | type II natural killer T cell | RECEPTOR | adaptive immunity | CD1 | innate immunity | KILLER T-CELLS | INNATE-LIKE | GLYCOLIPIDS | Hybridomas - metabolism | Corynebacterium glutamicum - genetics | Antigens, CD1d - immunology | Transferases (Other Substituted Phosphate Groups) - genetics | Antigens, Bacterial - immunology | Mycobacterium tuberculosis - immunology | Transferases (Other Substituted Phosphate Groups) - immunology | Cardiolipins - immunology | Galactosylceramides - metabolism | Receptors, Antigen, T-Cell, alpha-beta - immunology | Corynebacterium glutamicum - metabolism | Transferases (Other Substituted Phosphate Groups) - metabolism | Natural Killer T-Cells - metabolism | Myeloid Differentiation Factor 88 - immunology | Antigens, CD1d - genetics | Bacterial Proteins - immunology | Phospholipids - metabolism | Toll-Like Receptors - metabolism | Mycobacterium tuberculosis - metabolism | Phosphatidylglycerols - metabolism | Macrophages - immunology | Macrophages - microbiology | Cell Line | Antigen-Presenting Cells - metabolism | Mice, Inbred C57BL | Phosphatidylglycerols - immunology | Phospholipids - immunology | Toll-Like Receptors - immunology | Bacterial Proteins - genetics | Cells, Cultured | Myeloid Differentiation Factor 88 - genetics | Cardiolipins - metabolism | Antigen-Presenting Cells - immunology | Antigens, CD1d - metabolism | Mice, Knockout | Macrophages - metabolism | Animals | Galactosylceramides - immunology | Hybridomas - immunology | Bacterial Proteins - metabolism | Mice | Receptors, Antigen, T-Cell, alpha-beta - metabolism | Corynebacterium glutamicum - immunology | Antigens, Bacterial - metabolism | Myeloid Differentiation Factor 88 - metabolism | Natural Killer T-Cells - immunology | Autoimmunity | Killer cells | Antigen receptors, T cell | Receptors | Research | Properties | T cells | Biological Sciences | glycolipids | KazuyoshiKawakami | distinct | Mikrobiologi inom det medicinska området | VictorNizet | population | MoriyaTsuji | cd1 | receptor | Gurdyal S.Besra | Microbiology in the medical area | killer t-cells | innate-like | sulfatide | repertoire | KNizet | VBesra | GSTsuji | activation | Kawakami
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2012, Volume 109, Issue 41, pp. 16504 - 16509
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2013, Volume 288, Issue 42, pp. 30309 - 30319
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2011, Volume 108, Issue 49, pp. 19569 - 19574
The mechanism of action of 2-hydroxyoleic acid (2OHOA), a potent antitumor compound, has not yet been fully elucidated. Here we show that human cancer cells... 
T lymphocytes | Cell cycle | Cell lines | Rafts | Lipids | Cell membranes | Phospholipids | Fatty acids | Apoptosis | Tumors | Membrane lipids | Anticancer | Lung cancer | Membrane-lipid therapy | CANCER-CELLS | APOPTOSIS | DIACYLGLYCEROL | membrane lipids | PROTEIN | membrane-lipid therapy | MULTIDISCIPLINARY SCIENCES | SPHINGOLIPIDS | CERAMIDE | MINERVAL | anticancer | lung cancer | ANTICANCER ACTIVITY | METABOLISM | LIPID RAFTS | Apoptosis - drug effects | Membrane Microdomains - metabolism | Transferases (Other Substituted Phosphate Groups) - genetics | Humans | Transferases (Other Substituted Phosphate Groups) - antagonists & inhibitors | ras Proteins - metabolism | Immunoblotting | fas Receptor - metabolism | Glioma - metabolism | Glioma - genetics | Transferases (Other Substituted Phosphate Groups) - metabolism | Glioma - pathology | Bridged-Ring Compounds - pharmacology | Cell Membrane - metabolism | Membrane Proteins - metabolism | Oleic Acids - pharmacology | Cell Membrane - drug effects | Cell Survival - drug effects | Nerve Tissue Proteins - antagonists & inhibitors | Sphingomyelins - metabolism | Jurkat Cells | Membrane Proteins - genetics | Phosphodiesterase Inhibitors - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Nerve Tissue Proteins - genetics | Cells | Gene Expression Regulation, Enzymologic | Nerve Tissue Proteins - metabolism | Membrane Proteins - antagonists & inhibitors | Cell Cycle Checkpoints - drug effects | Cell Differentiation - drug effects | Cell Transformation, Neoplastic | Membrane Microdomains - drug effects | Cell Line, Tumor | Thiones - pharmacology | Care and treatment | Gliomas | Oleic acid | Development and progression | Properties | Health aspects | Myelin proteins | Biological Sciences | Physical Sciences
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2012, Volume 287, Issue 21, pp. 17589 - 17597
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2011, Volume 286, Issue 32, pp. 28544 - 28555
Lipid microdomains or caveolae, small invaginations of plasma membrane, have emerged as important elements for lipid uptake and glucose homeostasis.... 
SYNTHASE 2 | RAFTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ATHEROSCLEROSIS | MICE | CELL-GROWTH | ACID SPHINGOMYELINASE | CERAMIDE | ENDOCYTOSIS | PLASMA-MEMBRANE | CAVEOLIN-1 | CD36 Antigens - genetics | Fatty Liver - pathology | Transferases (Other Substituted Phosphate Groups) - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Diabetes Mellitus, Type 2 - metabolism | Fatty Liver - chemically induced | Obesity - genetics | Caveolae - pathology | Transferases (Other Substituted Phosphate Groups) - metabolism | CD36 Antigens - metabolism | Dietary Fats - pharmacology | Membrane Proteins - metabolism | Fatty Liver - genetics | Dietary Fats - adverse effects | Ceramides - metabolism | Fatty Liver - metabolism | Obesity - chemically induced | Sphingomyelins - metabolism | Caveolae - metabolism | Membrane Proteins - genetics | Caveolin 1 - genetics | Insulin Resistance - radiation effects | Nerve Tissue Proteins - genetics | Hep G2 Cells | Mice, Knockout | Obesity - metabolism | Obesity - pathology | Caveolin 1 - metabolism | Nerve Tissue Proteins - metabolism | Sphingomyelins - genetics | Ceramides - genetics | Animals | Insulin Resistance - genetics | Mice, Obese | Mice | Diabetes Mellitus, Type 2 - chemically induced | Diabetes Mellitus, Type 2 - pathology | Lipid Raft | Caveolae | Metabolic Syndrome | Lipid Droplet | Sphingolipid | Ceramide | Sphingomyelin | Lipids | Membrane Lipids | Sphingomyelin Synthase
Journal Article
The EMBO Journal, ISSN 0261-4189, 2004, Volume 23, Issue 1, pp. 33 - 44
Journal Article