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Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2007, Volume 50, Issue 15, pp. 3716 - 3729
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 17932 - 11
Low effectiveness and resistance to treatments are commonplace in disorders of the central nervous system (CNS). These issues concern mainly the blood-brain... 
TAT PROTEIN | GOLD NANOPARTICLES | CELLS | TRANSFERRIN RECEPTOR | DRUG-DELIVERY | MEMBRANE | MULTIDISCIPLINARY SCIENCES | INTRACELLULAR DELIVERY | TRANSDUCTION | N-METHYLATION | BRAIN | Phage display | Shuttles | Peptides | Blood-brain barrier | Computational neuroscience | Computer applications | Central nervous system | Homeostasis | Exploration | Biological activity
Journal Article
Journal Article
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 05/2009, Volume 29, Issue 21, pp. 6794 - 6808
The dopamine transporter (DAT) mediates reuptake of dopamine from the synaptic cleft and is a target for widely abused psychostimulants such as cocaine and... 
PROTEIN-KINASE-C | GENE DELIVERY | MEMBRANE | LENTIVIRAL VECTOR | IN-VIVO | MEDIATED ENDOCYTOSIS | DEPENDENT ENDOCYTOSIS | SURFACE EXPRESSION | MONOAMINE TRANSPORTERS | NEUROSCIENCES | AMINOBUTYRIC-ACID TRANSPORTER | Dopamine Plasma Membrane Transport Proteins - metabolism | Tyrosine 3-Monooxygenase - metabolism | Cocaine - metabolism | Dynamins - metabolism | rab5 GTP-Binding Proteins - genetics | Mesencephalon - cytology | Vesicular Monoamine Transport Proteins - metabolism | Humans | Maleimides - pharmacology | Protein Transport - physiology | Green Fluorescent Proteins - genetics | Protein Transport - drug effects | Dopamine Uptake Inhibitors - metabolism | rab5 GTP-Binding Proteins - metabolism | Mutation - physiology | Transfection - methods | Alanine - genetics | Time Factors | Fluorescence Recovery After Photobleaching - methods | Phorbol Esters - pharmacology | Indoles - pharmacology | Neurons - metabolism | Receptors, Transferrin - genetics | Neurons - drug effects | Animals, Newborn | Cocaine - chemistry | Green Fluorescent Proteins - metabolism | Cells, Cultured | Dopamine - pharmacology | Enzyme Inhibitors - pharmacology | Dynamins - genetics | Rats | Cocaine - analogs & derivatives | Dopamine Plasma Membrane Transport Proteins - genetics | Receptors, Transferrin - metabolism | Lysine - genetics | Animals | Dopamine Uptake Inhibitors - chemistry | Index Medicus
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 06/2014, Volume 467, Issue 1-2, pp. 113 - 122
Artemisinin (ART) and its analogues, such as dihydroartesunate (DHA) and artesunate (ATS), are sesquiterpene lactones with anticancer activities. In order to... 
Transferrin | Drug delivery | Anticancer | Artesunate | Adduct | Artemisinin | Keywords | DIHYDROARTEMISININ | APOPTOSIS | RECEPTOR | INHIBITION | HOLOTRANSFERRIN | TARGETED DRUG | GROWTH | PHARMACOLOGY & PHARMACY | DERIVATIVES | CYTOTOXICITY | BINDING | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Artemisinins - toxicity | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Antineoplastic Agents - administration & dosage | Chromatography, High Pressure Liquid | Antineoplastic Agents - toxicity | Drug Carriers | Antineoplastic Agents - metabolism | Dose-Response Relationship, Drug | Adenocarcinoma - metabolism | Lactones - administration & dosage | Liver Neoplasms - pathology | Molecular Structure | Artemisinins - chemistry | Lactones - chemistry | Drug Stability | Artemisinins - administration & dosage | Spectrometry, Fluorescence | Technology, Pharmaceutical - methods | Antineoplastic Agents - chemistry | Lactones - metabolism | Spectrophotometry, Ultraviolet | Chemistry, Pharmaceutical | Hep G2 Cells | Lactones - toxicity | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Transferrin - chemistry | Artemisinins - metabolism | Protein Conformation | Cell Proliferation - drug effects | Molecular Docking Simulation | Transferrin - metabolism | Nanotechnology | Carcinoma, Hepatocellular - metabolism | Fluorescence | Analysis | Cancer cells | Cancer | Lactones | Index Medicus
Journal Article
Redox Biology, ISSN 2213-2317, 04/2015, Volume 4, Issue C, pp. 308 - 320
Oxidative stress plays a major part in the pathogenesis of drug-induced liver injury. Yet, overcoming it with other xenobiotics impose additional risks. In... 
Drug-induced liver injury | Tocotrienol | Tocopherol | Antioxidant | UNITED-STATES | OXIDATIVE STRESS | ALPHA-TOCOTRIENOL | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACETAMINOPHEN HEPATOTOXICITY | NRF2 KNOCKOUT MICE | NATURAL VITAMIN-E | ANTIOXIDANT PROPERTIES | CELL-DEATH | GLUTATHIONE | TOCOPHEROLS | Tumor Necrosis Factor-alpha - metabolism | Reactive Oxygen Species - metabolism | Tumor Necrosis Factor-alpha - genetics | Caspase 3 - metabolism | Tocopherols - pharmacology | bcl-X Protein - genetics | Hepatocytes - metabolism | Hepatocytes - cytology | Proliferating Cell Nuclear Antigen - genetics | Protective Agents - pharmacology | Caspase 3 - genetics | Lipid Peroxidation - drug effects | Interleukin-6 - metabolism | Hepatocytes - drug effects | Hydrogen Peroxide - toxicity | Cell Survival - drug effects | Interleukin-6 - genetics | Signal Transduction | Acetaminophen - toxicity | Acetaminophen - antagonists & inhibitors | Gene Expression Regulation | Mitochondria - metabolism | Antioxidants - pharmacology | Mitochondria - drug effects | Reactive Oxygen Species - antagonists & inhibitors | Animals | Nitric Oxide Synthase Type II - genetics | Mice | Oxidative Stress - drug effects | Proliferating Cell Nuclear Antigen - metabolism | bcl-X Protein - metabolism | Hydrogen Peroxide - antagonists & inhibitors | Cell Line, Transformed | Nitric Oxide Synthase Type II - metabolism | Vitamin E - pharmacology | Index Medicus
Journal Article
Journal Article
Toxicon, ISSN 0041-0101, 2009, Volume 53, Issue 4, pp. 460 - 465
Saxitoxin (STX) contaminates seafood and freshwater catchments worldwide. Conjugation of STX with biotin would enable new biochemical methods to quantitate STX... 
Saxitoxin | Biotin | Conjugation | Saxiphilin | Avidin | Streptavidin | SHELLFISH POISONING TOXINS | SODIUM-CHANNEL | RECEPTOR-BINDING ASSAY | BIOASSAY | BIOACCUMULATION | TRANSFERRIN | PHARMACOLOGY & PHARMACY | TOXICOLOGY | WATER | Biotin - chemistry | Protein Binding | Molecular Structure | Saxitoxin - chemistry | Biotinylation | Tetrodotoxin | Index Medicus
Journal Article