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Advanced Materials, ISSN 0935-9648, 07/2019, Volume 31, Issue 30, pp. 1970218 - n/a
In article number 1900928, Gang Han, Yuanjie Niu, and co‐workers develop a prostate‐cancer‐specific genetic approach toward amplified MRI nanoparticles tumor... 
genetic probes | transferrin | nanomedicine | magnetic resonance imaging | prostate cancer | tumor‐targeting | Genetic aspects | Magnetic resonance imaging | Prostate cancer | Investigations | Tumors | Nanoparticles | Homing | Amplification | Biomarkers | Lesions | Prostate | Cancer
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1121 - 8
Human transferrin receptor 1 (CD71) guarantees iron supply by endocytosis upon binding of iron-loaded transferrin and ferritin. Arenaviruses and the malaria... 
SYSTEM | ENTRY | MECHANISM | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | DOXORUBICIN | TUMOR | VALIDATION | MICROSCOPY | BINDING | DELIVERY | Receptors, Virus - metabolism | Humans | Arenaviruses, New World - genetics | Arenaviruses, New World - metabolism | Plasmodium vivax - genetics | Substrate Specificity | Hemochromatosis Protein - chemistry | Receptors, Virus - genetics | Protozoan Proteins - genetics | Antigens, CD - genetics | Transferrin - genetics | Apoferritins - metabolism | Antigens, CD - metabolism | Protozoan Proteins - metabolism | Cloning, Molecular | Escherichia coli - metabolism | Viral Envelope Proteins - metabolism | Protozoan Proteins - chemistry | Antigens, CD - chemistry | Protein Interaction Domains and Motifs | Receptors, Transferrin - genetics | Binding Sites | Recombinant Proteins - metabolism | Protein Conformation, alpha-Helical | Gene Expression | Plasmodium vivax - metabolism | Viral Envelope Proteins - genetics | Genetic Vectors - chemistry | Genetic Vectors - metabolism | Recombinant Proteins - chemistry | Apoferritins - chemistry | Apoferritins - genetics | Hemochromatosis Protein - metabolism | Recombinant Proteins - genetics | Receptors, Transferrin - metabolism | Cryoelectron Microscopy | Receptors, Virus - chemistry | Protein Conformation, beta-Strand | Escherichia coli - genetics | Hemochromatosis Protein - genetics | Viral Envelope Proteins - chemistry | Transferrin - chemistry | Protein Binding | HeLa Cells | Transferrin - metabolism | Receptors, Transferrin - chemistry | Binding | Vector-borne diseases | Transferrin | Endocytosis | Malaria | Ferritin | Iron | Epitopes | Electron microscopy | Cellular structure | Mimicry
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2012, Volume 7, Issue 6, p. e38339
The existence of multiple inherited disorders of iron metabolism suggests genetic contributions to iron deficiency. We previously performed a genome-wide... 
OVERLOAD SCREENING HEIRS | HOMEOSTASIS | ASSAY | TRANSFERRIN RECEPTOR | BIOLOGY | TMPRSS6 GENE | ANEMIA | MUTATIONS | HEREDITARY HEMOCHROMATOSIS | DEFICIENCY | GENOME-WIDE ASSOCIATION | Prognosis | Follow-Up Studies | Humans | Middle Aged | Asian Continental Ancestry Group - genetics | Hemochromatosis - blood | Hispanic Americans - statistics & numerical data | Male | Iron Overload - blood | Ethnic Groups - genetics | Serine Endopeptidases - genetics | Adult | Female | Hemochromatosis - genetics | Iron - blood | European Continental Ancestry Group - genetics | Hispanic Americans - genetics | Iron Overload - genetics | Membrane Proteins - genetics | California - epidemiology | Biomarkers - analysis | African Americans - genetics | European Continental Ancestry Group - statistics & numerical data | Genotype | African Americans - statistics & numerical data | Iron Overload - epidemiology | Polymorphism, Single Nucleotide - genetics | Hemochromatosis - epidemiology | Asian Continental Ancestry Group - statistics & numerical data | Receptors, Cell Surface - genetics | Analysis | Iron deficiency anemia | Genes | Genomics | Hispanic Americans | Ferritin | African Americans | Physiological aspects | Genetic research | Genetic aspects | Single nucleotide polymorphisms | Health sciences | Biomedical research | Populations | Laboratories | Iron | Genomes | Single-nucleotide polymorphism | Epidemiology | Toxicology | Chromosome 10 | Hemoglobin | Physiology | Public health | Deoxyribonucleic acid--DNA | Chromosome 18 | CUBN gene | Nutrient deficiency | Hemochromatosis | Anemia | Whites | Metabolism | Minority & ethnic groups | Hereditary diseases | Medicine | Studies | Mutation | Deoxyribonucleic acid | DNA
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 4/2009, Volume 185, Issue 2, pp. 305 - 321
Autophagy, an intracellular degradative pathway, maintains cell homeostasis under normal and stress conditions. Nascent double-membrane autophagosomes... 
Starvation | Transferrins | 3T3 cells | Small interfering RNA | HeLa cells | Antibodies | CHO cells | Endosomes | Golgi apparatus | P branes | CORE MACHINERY | TRANSPORT | UNFOLDED PROTEIN RESPONSE | MULTIVESICULAR BODIES | MEMBRANE | EPSILON-COP | ENDOCYTIC PATHWAYS | BETA-COP | CELL MUTANT | GOLGI-COMPLEX | CELL BIOLOGY | Mannose-Binding Lectins - metabolism | RNA, Small Interfering - genetics | Membrane Glycoproteins - metabolism | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Sequestosome-1 Protein | Humans | Ubiquitin - metabolism | Autophagy - physiology | Coat Protein Complex I - metabolism | Recombinant Fusion Proteins - metabolism | Endosomes - metabolism | Protein Subunits - metabolism | Lysosomal-Associated Membrane Protein 1 - genetics | Membrane Proteins - metabolism | Protein Subunits - genetics | Biomarkers - metabolism | Cell Line | Membrane Proteins - genetics | Lysosomal-Associated Membrane Protein 2 - genetics | Phagosomes - metabolism | Ubiquitin - genetics | Coat Protein Complex I - genetics | Membrane Glycoproteins - genetics | Animals | Mannose-Binding Lectins - genetics | Adaptor Proteins, Signal Transducing - genetics | Recombinant Fusion Proteins - genetics | Golgi Apparatus - metabolism | Lysosomal-Associated Membrane Protein 1 - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Transferrin - metabolism | Lysosomal-Associated Membrane Protein 2 - metabolism | RNA, Small Interfering - metabolism | Ubiquitin | Gas vesicles | Physiological aspects | Research | Phagocytosis
Journal Article
Human Gene Therapy, ISSN 1043-0342, 06/2008, Volume 19, Issue 6, pp. 589 - 600
Targeting viral entry is one of the major goals in the development of vectors for gene therapy. Ideally, the coupling of each new targeting motif would not... 
TRANSDUCTION EFFICIENCY | MEDICINE, RESEARCH & EXPERIMENTAL | GENE DELIVERY | RECOMBINANT BACULOVIRUS | ESCHERICHIA-COLI | VECTOR PURIFICATION | MAMMALIAN-CELLS | LENTIVIRAL VECTORS | NUCLEAR POLYHEDROSIS-VIRUS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IN-VIVO | PROTEIN-IX | GENETICS & HEREDITY | Genetic Therapy | Membrane Glycoproteins - metabolism | Baculoviridae - metabolism | Humans | Glycoproteins - metabolism | Peptides - genetics | Virion - genetics | Baculoviridae - genetics | Magnetics | Recombinant Fusion Proteins - metabolism | Transferrin - genetics | Carbon-Nitrogen Ligases - genetics | Virus Internalization | Peptides - metabolism | Escherichia coli Proteins - biosynthesis | Carbon-Nitrogen Ligases - biosynthesis | Viral Envelope Proteins - metabolism | Transduction, Genetic - methods | Glycoproteins - genetics | Streptavidin - chemistry | Viral Envelope Proteins - genetics | Biotinylation | Epidermal Growth Factor - genetics | Genetic Vectors - metabolism | Rats | Repressor Proteins - genetics | Baculoviridae - isolation & purification | Virion - metabolism | Genetic Vectors - genetics | Membrane Glycoproteins - genetics | Genetic Vectors - isolation & purification | Animals | Repressor Proteins - biosynthesis | Virion - isolation & purification | Cell Line, Tumor | Escherichia coli Proteins - genetics | Recombinant Fusion Proteins - genetics | Membrane Cofactor Protein - genetics | Usage | Genetic vectors | Baculoviruses | Physiological aspects | Genetic aspects | Biotin | Research | Gene therapy | Health aspects
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 12/2010, Volume 191, Issue 7, pp. 1381 - 1393
Clathrin-mediated endocytosis (CME) is the major pathway for concentrative uptake of receptors and receptor—ligand complexes (cargo). Although constitutively... 
Molecules | Receptors | Endocytosis | Internalization | Imaging | Fluorescence | Ligands | Physiological regulation | Freight | Transferrin receptors | MONOVALENT STREPTAVIDIN | BIOTIN LIGASE | MEMBRANE MICRODOMAINS | CARGO | SORTING SIGNAL | MEDIATED ENDOCYTOSIS | GROWTH-FACTOR | PROTEINS | ADAPTER COMPLEX | BINDING | CELL BIOLOGY | Coated Pits, Cell-Membrane - ultrastructure | Humans | Cercopithecus aethiops | Recombinant Fusion Proteins - metabolism | Carbon-Nitrogen Ligases - genetics | Adaptor Protein Complex sigma Subunits - metabolism | Coated Pits, Cell-Membrane - physiology | Epithelial Cells - physiology | Adaptor Protein Complex 2 - metabolism | Clathrin Light Chains - metabolism | Biotin - metabolism | Cell Membrane - metabolism | Receptors, Transferrin - genetics | Clathrin Light Chains - genetics | Epithelial Cells - cytology | Biotinylation - genetics | Cell Line | Transduction, Genetic | Rats | Repressor Proteins - genetics | Adaptor Protein Complex 2 - genetics | Adaptor Protein Complex sigma Subunits - genetics | Receptors, Transferrin - metabolism | Streptavidin - genetics | Endocytosis - physiology | Receptor Aggregation - physiology | Animals | Streptavidin - metabolism | Escherichia coli Proteins - genetics | Recombinant Fusion Proteins - genetics | Biotinylation - methods | Kinetics | Protein Binding - physiology | Transferrin | Cell receptors | Clathrin | Research | Properties
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 05/2017, Volume 26, Issue 10, pp. 1966 - 1978
Journal Article
Wiley Interdisciplinary Reviews: RNA, ISSN 1757-7004, 07/2011, Volume 2, Issue 4, pp. 582 - 600
Endonuclease cleavage was one of the first identified mechanisms of mRNA decay but until recently it was thought to play a minor role to the better‐known... 
ALBUMIN GENE-EXPRESSION | POLYSOMAL RIBONUCLEASE-1 | IN-VITRO | UNFOLDED PROTEIN RESPONSE | 3'-UNTRANSLATED REGION | CODING REGION | BINDING-PROTEIN | XENOPUS LIVER | MAMMALIAN-CELLS | ENDORIBONUCLEASE G3BP | CELL BIOLOGY | Interleukin-8 - genetics | Endonucleases - genetics | Endoribonucleases - genetics | Ribonucleases - genetics | Humans | Lipoproteins, VLDL - genetics | Male | Endonucleases - metabolism | RNA, Messenger - metabolism | Ribonucleases - metabolism | Poly-ADP-Ribose Binding Proteins | DNA-(Apurinic or Apyrimidinic Site) Lyase - genetics | RNA Helicases | Insulin-Like Growth Factor II - genetics | Telomerase - genetics | Apolipoproteins - genetics | Female | Telomerase - metabolism | Receptors, Transferrin - genetics | RNA Recognition Motif Proteins | Protein-Serine-Threonine Kinases - metabolism | RNA Stability - physiology | Endoribonucleases - metabolism | RNA, Messenger - genetics | Protein-Serine-Threonine Kinases - genetics | RNA Stability - genetics | Homeodomain Proteins - genetics | Carrier Proteins - genetics | DNA Helicases | Animals | Carrier Proteins - metabolism | DNA-(Apurinic or Apyrimidinic Site) Lyase - metabolism | Models, Biological | alpha-Globins - genetics | Mice | Cyclin-Dependent Kinase Inhibitor p27 - genetics | miRNA | Exonuclease | Surveillance | Endonuclease | mRNA turnover | endonuclease | cleavage | NMD | deadenylation | mRNA decay
Journal Article
IUBMB Life, ISSN 1521-6543, 06/2017, Volume 69, Issue 6, pp. 389 - 398
Journal Article
Journal Article