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2000, Methods in molecular biology, ISBN 0896036464, Volume 142., x, 175
The recent isolation and identification of the TGFß receptors, as well as their intracellular mediating proteins, has driven the development of many new... 
Transforming growth factors-beta | Laboratory manuals | Transforming growth factors | Cytology | Cell Biology | Life Sciences | Books | protocols | Transforming growth factor-^b
Book
Journal Article
Oncogene, ISSN 0950-9232, 12/2010, Volume 29, Issue 49, pp. 6485 - 6498
Transforming growth factor-beta (TGF-beta) and epidermal growth factor (EGF) have critical roles in regulating the metastasis of aggressive breast cancers, yet... 
FAK | breast cancer | TGF-b | invasion | metastasis | EGFR | ACTIVATION | MAMMARY-CARCINOMA CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR | FACTOR RECEPTOR INHIBITION | PROLIFERATION | LINES | CELL BIOLOGY | TGF-beta | ONCOLOGY | GENETICS & HEREDITY | GENE-EXPRESSION | FOCAL ADHESION KINASE | Animal models | Aggressive behavior | Epidermal growth factor receptors | Epithelial cells | Invasiveness | MAP kinase | Breast cancer | Transforming growth factor- beta | Metastases | E- double prime Cadherin | Epidermal growth factor | Veins | Mammary gland | Focal adhesion kinase | spheroids | Tumors | Cadherins - metabolism | Humans | Mammary Neoplasms, Experimental - metabolism | Breast Neoplasms - metabolism | Receptor, Epidermal Growth Factor - metabolism | Epithelial-Mesenchymal Transition | Mammary Neoplasms, Experimental - pathology | Female | Indoles - pharmacology | p38 Mitogen-Activated Protein Kinases - metabolism | Carcinoma - secondary | Mammary Neoplasms, Experimental - drug therapy | Carcinoma - drug therapy | Focal Adhesion Protein-Tyrosine Kinases - metabolism | Epidermal Growth Factor - metabolism | Sulfonamides - pharmacology | Breast Neoplasms - drug therapy | Transforming Growth Factor beta - pharmacology | Animals | Receptors, Transforming Growth Factor beta - metabolism | Breast Neoplasms - pathology | Cell Line, Tumor | Mice | Carcinoma - metabolism | Epidermal Growth Factor - pharmacology | Transforming Growth Factor beta - metabolism | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, ISSN 1073-449X, 07/2016, Volume 194, Issue 1, pp. 84 - 96
RATIONALE: Recent findings suggesting transforming growth factor (TGF)-beta(1) activation by mechanical stimuli in vitro raised the question of whether this... 
transforming growth factor -beta | TGF-BETA-1 ACTIVATION | mechanotransduction | ventilation | mechanical stress | LATENT TGF-BETA | FIBROBLASTS | MATRIX DEPOSITION | INHIBITION | EPITHELIAL-CELLS | STIFFNESS | INTEGRINS | RESPIRATORY SYSTEM | pulmonary fibrosis | MICE | CRITICAL CARE MEDICINE
Journal Article
EUROPEAN JOURNAL OF CELL BIOLOGY, ISSN 0171-9335, 09/2008, Volume 87, Issue 8-9, pp. 601 - 615
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 01/2016, Volume 291, Issue 1, pp. 382 - 392
TGF-beta is a pleiotropic cytokine that regulates a wide range of cellular actions and pathophysiological processes. TGF-beta signaling is spatiotemporally... 
PATHWAYS | DOMAIN | transforming growth factor beta (TGF-B) | TGF-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | CANCER | ubiquitylation (ubiquitination) | STRUCTURAL BASIS | NEGATIVE REGULATION | NUCLEUS | cell signaling | SMAD transcription factor | TUMOR-SUPPRESSOR | DEGRADATION | protein-protein interaction | signaling regulation | protein degradation | Smad7 | PROGRESSION
Journal Article
Journal Article
Hepatology, ISSN 0270-9139, 04/2019, Volume 69, Issue 4, pp. 1375 - 1378
Journal Article
KIDNEY INTERNATIONAL, ISSN 0085-2538, 08/2011, Volume 80, Issue 4, pp. 358 - 368
Enhanced transforming growth factor-beta 1 (TGF-beta 1) expression in renal cells promotes fibrosis and hypertrophy during the progression of diabetic... 
CANCER-CELLS | DIABETIC KIDNEY-DISEASE | INDUCED COLLAGEN EXPRESSION | E-CADHERIN | MIR-200 FAMILY | REPRESSORS ZEB1 | EPITHELIAL-MESENCHYMAL TRANSITION | TGF-beta | GROWTH-FACTOR-BETA | cell signaling | UROLOGY & NEPHROLOGY | fibrosis | GENE ACTIVATION | UP-REGULATION | diabetic nephropathy | gene expression | Circuits | Transforming growth factor- beta 1
Journal Article
Hepatology, ISSN 0270-9139, 02/2014, Volume 59, Issue 2, pp. 483 - 495
Transforming growth factor beta (TGF‐β) signaling activates Smad‐ and TGF‐β‐activated kinase 1 (TAK1)‐dependent signaling to regulate cell survival,... 
FIBROSIS | OBESITY | TGF-BETA | TAK1 | FATTY LIVER-DISEASE | KINASE | ANTIBODY | NONALCOHOLIC STEATOHEPATITIS | GASTROENTEROLOGY & HEPATOLOGY | PROGRESSION | Reactive Oxygen Species | Protein-Serine-Threonine Kinases | Lipids | Male | Choline Deficiency | Kinases | Rodents | Hepatology | Gene Deletion | Transforming Growth Factor beta | Disease Models, Animal | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Lipid Metabolism | Mice, Transgenic | Metabolism | Gene expression | Disease Progression | Fatty Liver | transforming growth factor-beta type II receptor | Animals | Hepatocytes | Smad Proteins | Receptors, Transforming Growth Factor beta | Mice | Apoptosis | Protein-Serine-Threonine Kinases - deficiency | Receptors, Transforming Growth Factor beta - genetics | Reactive Oxygen Species - metabolism | Fatty Liver - pathology | Hepatocytes - pathology | Receptors, Transforming Growth Factor beta - physiology | Choline Deficiency - metabolism | Hepatocytes - physiology | Protein-Serine-Threonine Kinases - physiology | Fatty Liver - physiopathology | Protein-Serine-Threonine Kinases - genetics | Transforming Growth Factor beta - physiology | Smad Proteins - physiology | Choline Deficiency - physiopathology | Signal Transduction - physiology | Apoptosis - physiology | Lipid Metabolism - physiology | Fatty Liver - etiology | Receptors, Transforming Growth Factor beta - deficiency | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, pp. e90353 - e90353
Background: In advanced cancers, transforming growth factor-beta (TGFb) promotes tumor growth and metastases and suppresses host antitumor immunity. GC1008 is... 
SURVIVAL | EPITHELIAL-MESENCHYMAL TRANSDIFFERENTIATION | INHIBITION | SOLID TUMORS | EFFICACY | VIVO | MULTIDISCIPLINARY SCIENCES | METASTATIC BREAST-CANCER | KERATOACANTHOMAS | T-CELLS | PROGRESSION | Intravenous administration | Toxicity | Transforming growth factor-b | Transforming growth factor-a | Immunity | Metastases | Anticancer properties | Renal cell carcinoma | Squamous cell carcinomas | Bioindicators | Safety | Lesions | Melanomas | Cancer treatment | Medical treatment | Melanoma | Pharmacology | Patients | Constraining | Isoforms | Monoclonal antibodies | Biomarkers | Antitumor activity | Pharmacokinetics | Clear cell-type renal cell carcinoma | Humans | Middle Aged | Antibodies, Monoclonal - therapeutic use | Male | Tomography, X-Ray Computed | Antineoplastic Agents - therapeutic use | Positron-Emission Tomography | Kidney Neoplasms - diagnosis | Aged, 80 and over | Transforming Growth Factor beta - antagonists & inhibitors | Adult | Female | Antineoplastic Agents - pharmacology | Carcinoma, Renal Cell - drug therapy | Carcinoma, Renal Cell - pathology | Antibodies, Monoclonal - pharmacology | Treatment Outcome | Melanoma - pathology | Transforming Growth Factor beta - blood | Carcinoma, Renal Cell - diagnosis | Melanoma - drug therapy | Kidney Neoplasms - pathology | Aged | Kidney Neoplasms - drug therapy | Neoplasm Staging | Oncology, Experimental | Clinical trials | Bone morphogenetic proteins | Research | Carcinoma, Renal cell | Metastasis | Transforming growth factors | Cancer | Index Medicus
Journal Article