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Hypertension, ISSN 0194-911X, 10/2009, Volume 54, Issue 4, pp. 877 - 884
Journal Article
Hepatology, ISSN 0270-9139, 12/2012, Volume 56, Issue 6, pp. 2255 - 2267
Liver cirrhosis is a predominant risk factor for hepatocellular carcinoma (HCC). However, the mechanism underlying the progression from cirrhosis to HCC... 
PROGENITOR CELLS | HEPATOCELLULAR-CARCINOMA | STEM-CELLS | HEPATOCYTES | TGF-BETA | EPIGENETIC REGULATION | PTEN | SELF-RENEWAL | TUMORIGENICITY | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | Rats, Wistar | TOR Serine-Threonine Kinases - metabolism | Humans | Glycoproteins - metabolism | Liver Neoplasms, Experimental - chemically induced | Male | MicroRNAs - metabolism | Proto-Oncogene Proteins c-akt - genetics | Antigens, CD - metabolism | Epithelial Cell Adhesion Molecule | Pluripotent Stem Cells - pathology | Liver Neoplasms, Experimental - metabolism | Peptides - metabolism | Neoplastic Stem Cells - metabolism | Diethylnitrosamine | Liver Cirrhosis - metabolism | Antigens, Neoplasm - metabolism | Biomarkers, Tumor - metabolism | Antigens, Differentiation - metabolism | Liver Neoplasms, Experimental - pathology | Proto-Oncogene Proteins c-akt - metabolism | STAT3 Transcription Factor - metabolism | Liver - metabolism | Mice, Inbred C57BL | PTEN Phosphohydrolase - metabolism | Rats | Mice, SCID | AC133 Antigen | Cell Adhesion Molecules - metabolism | Cell Transformation, Neoplastic - metabolism | Pluripotent Stem Cells - metabolism | Thy-1 Antigens - metabolism | Transforming Growth Factor beta - pharmacology | Animals | Pluripotent Stem Cells - drug effects | Liver Cirrhosis - pathology | Mice, Inbred NOD | Mice | Cell Transformation, Neoplastic - pathology | Transforming Growth Factor beta - metabolism | Proteins | Liver cancer | Liver cirrhosis | Hepatology | Index Medicus
Journal Article
Journal Article
NATURE MEDICINE, ISSN 1078-8956, 02/2015, Volume 21, Issue 2, pp. 150 - 158
Journal Article
Nature Immunology, ISSN 1529-2908, 12/2008, Volume 9, Issue 12, pp. 1347 - 1355
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 10/2010, Volume 207, Issue 11, pp. 2331 - 2341
Foxp3-expressing regulatory T (T reg) cells have been implicated in parasite-driven inhibition of host immunity during chronic infection. We addressed whether... 
B-CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | TH2 RESPONSES | PROTECTIVE IMMUNITY | TRANSCRIPTION FACTOR FOXP3 | IN-VIVO | AIRWAY INFLAMMATION | NEMATODE INFECTION | POLYGYRUS INFECTION | IMMUNOLOGY | ORAL ANTIGEN | AUTOIMMUNE-DISEASE | Receptors, Transforming Growth Factor beta - genetics | Strongylida Infections - metabolism | Receptors, Transforming Growth Factor beta - immunology | Smad3 Protein - immunology | Nematospiroides dubius - metabolism | Th2 Cells - immunology | T-Lymphocytes, Regulatory - immunology | Th1 Cells - metabolism | Host-Parasite Interactions - genetics | Phosphorylation - genetics | Smad2 Protein - genetics | Dioxoles - pharmacology | Phosphorylation - immunology | Protein-Serine-Threonine Kinases - metabolism | Smad2 Protein - metabolism | Mice, Transgenic | Signal Transduction - genetics | Antigens, Helminth - immunology | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Signal Transduction - drug effects | Mice | Mice, Inbred BALB C | Chronic Disease | Forkhead Transcription Factors - immunology | T-Lymphocytes, Regulatory - metabolism | Antigens, Helminth - metabolism | Strongylida Infections - genetics | Smad3 Protein - metabolism | Th1 Cells - immunology | Nematospiroides dubius - immunology | Signal Transduction - immunology | Smad3 Protein - genetics | Strongylida Infections - immunology | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Benzamides - pharmacology | Transforming Growth Factor beta - immunology | Forkhead Transcription Factors - biosynthesis | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Protein-Serine-Threonine Kinases - genetics | Host-Parasite Interactions - immunology | Forkhead Transcription Factors - genetics | Th2 Cells - metabolism | Gene Expression Regulation - drug effects | Host-Parasite Interactions - drug effects | Smad2 Protein - immunology | Animals | Transforming Growth Factor beta - genetics | Receptors, Transforming Growth Factor beta - metabolism | Protein-Serine-Threonine Kinases - immunology | Cell Proliferation - drug effects | Transforming Growth Factor beta - metabolism | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2013, Volume 288, Issue 42, pp. 30708 - 30719
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 508, Issue 1, pp. 118 - 122
Treatment of BRAF(V600E) mutant melanoma by small molecule drugs that target the BRAF or MEK kinases can be effective, but resistance develops invariably(1,2).... 
GROWTH-FACTOR RECEPTOR | BRAF INHIBITOR | RAF INHIBITION | CELLS | MULTIDISCIPLINARY SCIENCES | IMPROVED SURVIVAL | DIFFERENTIATION | C-JUN | CANCER | EXPRESSION | EGFR | Receptor, Epidermal Growth Factor - genetics | Humans | Receptor Protein-Tyrosine Kinases - biosynthesis | Cellular Senescence - drug effects | Melanoma - enzymology | Antineoplastic Agents - administration & dosage | Receptor, Platelet-Derived Growth Factor beta - genetics | Indoles - administration & dosage | Mitogen-Activated Protein Kinase Kinases - metabolism | Receptor, Epidermal Growth Factor - metabolism | Flow Cytometry | Melanoma - genetics | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | SOXE Transcription Factors - deficiency | Proto-Oncogene Proteins B-raf - metabolism | Receptor, Platelet-Derived Growth Factor beta - metabolism | Receptor, Epidermal Growth Factor - biosynthesis | Gene Library | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Melanoma - pathology | Receptor Protein-Tyrosine Kinases - metabolism | Sulfonamides - pharmacology | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Protein Kinase Inhibitors - administration & dosage | Transforming Growth Factor beta - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Receptor Protein-Tyrosine Kinases - genetics | Signal Transduction - drug effects | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | RNA, Small Interfering | Transforming Growth Factor beta - metabolism | Receptor, Platelet-Derived Growth Factor beta - biosynthesis | Sulfonamides - administration & dosage | Drug Resistance, Neoplasm - drug effects | SOXE Transcription Factors - genetics | Proteins | Biopsy | Rodents | Genes | Melanoma | Mutation | Kinases | Drug resistance | Patients | Tumors | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 05/2016, Volume 44, Issue 5, pp. 1127 - 1139
Journal Article
Oncogene, ISSN 0950-9232, 12/2010, Volume 29, Issue 49, pp. 6485 - 6498
Journal Article
NATURE MEDICINE, ISSN 1078-8956, 03/2012, Volume 18, Issue 3, pp. 429 - U192
Journal Article