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Oncogene, ISSN 0950-9232, 12/2012, Volume 31, Issue 50, pp. 5162 - 5171
Journal Article
ONCOGENE, ISSN 0950-9232, 09/2012, Volume 31, Issue 37, pp. 4150 - 4163
MicroRNAs (miRNAs) as modulators of gene expression have been described to display both tumor-promoting and tumor-suppressive functions. Although their role... 
ACTIVATION | ANGIOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | miR-520c | breast cancer | NF-kappaB | PROLIFERATION | MICRORNAS | ER-negative | CELL BIOLOGY | TGF-beta | INVASION | miR-373 | ONCOLOGY | EMBRYONIC STEM-CELLS | GENETICS & HEREDITY | BONE METASTASIS | GROWTH-FACTOR | UP-REGULATION | EXPRESSION | Receptors, Estrogen - metabolism | Receptors, Transforming Growth Factor beta - genetics | Humans | Gene Expression Regulation, Neoplastic | MicroRNAs - metabolism | NF-kappa B - metabolism | Gene Expression Profiling | Receptors, Estrogen - deficiency | Transcription Factor RelA - genetics | Breast Neoplasms - metabolism | Parathyroid Hormone-Related Protein - biosynthesis | Angiopoietin-like 4 Protein | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Female | Protein-Serine-Threonine Kinases - metabolism | Angiopoietins - biosynthesis | Signal Transduction | Interleukin-8 - biosynthesis | Protein-Serine-Threonine Kinases - genetics | Parathyroid Hormone-Related Protein - metabolism | Neoplasm Metastasis - genetics | Plasminogen Activator Inhibitor 1 - biosynthesis | Breast Neoplasms - genetics | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Receptors, Transforming Growth Factor beta - metabolism | Transcription Factor RelA - metabolism | Cell Line, Tumor | Interleukin-6 - biosynthesis | Transforming Growth Factor beta - metabolism | Index Medicus | Tumor cells | Estrogen receptors | Breast cancer | Genomes | Inflammation | Transforming growth factor- beta | Gene expression | Lymph nodes | Metastases | Parathyroid hormone-related protein | plasminogen | Signal transduction | NF- Kappa B protein | Tumor suppressor genes | miRNA | RelA protein | Interleukin 8 | Tumors
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2009, Volume 284, Issue 46, pp. 31523 - 31531
Journal Article
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 7/2009, Volume 58, Issue 7, pp. 1033 - 1045
Lenalidomide (Revlimid®; CC-5013) and pomalidomide (CC-4047) are IMiDs® proprietary drugs having immunomodulatory properties that have both shown activity in... 
Immunomodulatory drugs | Biomedicine | Immunology | Lenalidomide | T regulatory cells | Cancer Research | Oncology | Pomalidomide | IMiDs | MULTIPLE-MYELOMA | DENILEUKIN DIFTITOX | THERAPEUTIC IMPLICATIONS | IMiDs (R) | PERIPHERAL-BLOOD | IMMUNOLOGY | TUMOR-INFILTRATING LYMPHOCYTES | CANCER-PATIENTS | ONCOLOGY | IN-VIVO | THALIDOMIDE ANALOG | ANTITUMOR IMMUNITY | Forkhead Transcription Factors - immunology | Receptors, Nerve Growth Factor - immunology | Receptors, Transforming Growth Factor beta - immunology | Receptors, Nerve Growth Factor - drug effects | Humans | Receptors, Nerve Growth Factor - metabolism | Thalidomide - pharmacology | Colonic Neoplasms - metabolism | Receptors, OX40 - immunology | T-Lymphocytes, Regulatory - immunology | Thalidomide - analogs & derivatives | Receptors, OX40 - metabolism | Transforming Growth Factor beta - drug effects | Colonic Neoplasms - immunology | Forkhead Transcription Factors - metabolism | Interleukin-10 - metabolism | Female | Antineoplastic Agents - pharmacology | Forkhead Transcription Factors - antagonists & inhibitors | Immunosuppressive Agents - pharmacology | Receptors, Tumor Necrosis Factor - metabolism | Transforming Growth Factor beta - immunology | Glucocorticoid-Induced TNFR-Related Protein | T-Lymphocytes, Regulatory - drug effects | Animals | Receptors, Transforming Growth Factor beta - drug effects | Receptors, Transforming Growth Factor beta - metabolism | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Receptors, Tumor Necrosis Factor - immunology | Interleukin-10 - immunology | Transforming Growth Factor beta - metabolism | Receptors, Tumor Necrosis Factor - drug effects | Receptors, OX40 - antagonists & inhibitors | Care and treatment | Dexamethasone | Multiple myeloma | Angiogenesis inhibitors | Transforming growth factors | T cells | Cancer | Index Medicus
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2011, Volume 286, Issue 32, pp. 28097 - 28110
In the postnatal vasculature, fully differentiated and quiescent vascular smooth muscle cells (VSMCs) in a "contractile" phenotype are required for the normal... 
TRANSCRIPTION FACTORS | MYOCARDIN | SIGNALING PATHWAYS | BIOCHEMISTRY & MOLECULAR BIOLOGY | EMBRYONIC STEM-CELLS | CARDIAC-HYPERTROPHY | SERUM RESPONSE FACTOR | ZINC-FINGER PROTEIN | GENE-EXPRESSION | DIFFERENTIATION | SMAD | Oncogene Proteins, Fusion - metabolism | Muscle, Smooth, Vascular - metabolism | Active Transport, Cell Nucleus - physiology | Bone Morphogenetic Protein 4 - genetics | Humans | MicroRNAs - metabolism | Bone Morphogenetic Protein 4 - metabolism | DNA-Binding Proteins - metabolism | Cell Nucleus - metabolism | Muscle Proteins - metabolism | Trans-Activators - genetics | Myocytes, Smooth Muscle - cytology | Myocytes, Smooth Muscle - metabolism | Cell Line | Kruppel-Like Transcription Factors - biosynthesis | DNA-Binding Proteins - genetics | Muscle, Smooth, Vascular - cytology | Down-Regulation - physiology | Muscle Proteins - genetics | Transcription, Genetic - physiology | Animals | Cell Nucleus - genetics | Oncogene Proteins, Fusion - genetics | Muscle Contraction - physiology | Trans-Activators - metabolism | Mice | MicroRNAs - genetics | Kruppel-Like Transcription Factors - genetics | Transforming Growth Factor beta - metabolism | Index Medicus | Gene Transcription | Smad Transcription Factor | Bone Morphogenetic Protein (BMP) | Transcription Regulation | Transforming Growth Factor β (TGFbeta) | MicroRNA | Signal Transduction | RNA Silencing | Cell Differentiation | Transcription Factors | Smooth Muscle
Journal Article
Neuron, ISSN 0896-6273, 05/2017, Volume 94, Issue 4, pp. 759 - 773.e8
Microglia, the resident macrophages of the CNS, engage in various CNS-specific functions that are critical for development and health. To better study... 
CSF1R | phagocytosis | maturation | inflammation | neurodegeneration | TGF-β | cholesterol | transplant | microglia | astrocyte | IDENTITY | GROWTH-FACTOR-BETA | PROGENITOR-CELL | BRAIN-INJURY | RNA-SEQ | ASTROCYTE | MACROPHAGES | MOUSE | RAMIFICATION | EXPRESSION | NEUROSCIENCES | Microglia - metabolism | Transforming Growth Factor beta2 - metabolism | Humans | Transcriptome | Interleukins - metabolism | Microglia - immunology | Macrophage Colony-Stimulating Factor - pharmacology | Serum | Cell Culture Techniques | Interleukins - pharmacology | Microglia - cytology | Cell Survival - drug effects | Phagocytosis - drug effects | Microglia - drug effects | Phagocytosis - immunology | Rats | Macrophage Colony-Stimulating Factor - metabolism | Cholesterol - metabolism | Transforming Growth Factor beta2 - pharmacology | Transforming Growth Factor beta - pharmacology | Animals | Cholesterol - pharmacology | Mice | Transforming Growth Factor beta - metabolism | Astrocytes - metabolism | Culture Media, Conditioned - metabolism | Medical colleges | Bone morphogenetic proteins | Macrophages | Transforming growth factors | Gene expression | Neurophysiology | Genes | Cell culture | Cell survival | Macrophage colony-stimulating factor | Central nervous system | Homeostasis | Exposure | Survival | Cholesterol | Microglia | Phagocytes | Rodents | Morphology | Growth factors | Index Medicus
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 03/2018, Volume 26, Issue 5, pp. 1026 - 1034
Journal Article
Circulation, ISSN 0009-7322, 02/2009, Volume 119, Issue 4, pp. 566 - 576
Background-Recent genetic studies have highlighted the role of the bone morphogenetic protein (BMP)/transforming growth factor (TGF)-beta signaling pathways in... 
Pathology | Hypoxia | Hemodynamics | Vessels | Hypertension, pulmonary | FIBROSIS | hypoxia | CARDIAC & CARDIOVASCULAR SYSTEMS | pathology | BMPR2 | hypertension, pulmonary | SMOOTH | PROLIFERATION | MUSCLE-CELLS | hemodynamics | FEATURES | ARTERIAL-HYPERTENSION | II RECEPTOR | PERIPHERAL VASCULAR DISEASE | MUTATIONS | vessels | Monocrotaline | Male | RNA, Messenger - metabolism | Hypertension, Pulmonary - chemically induced | Cell Movement - physiology | Quinolines - pharmacology | Hypoxia - metabolism | Bone Morphogenetic Proteins - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Benzamides - pharmacology | Hypertension, Pulmonary - drug therapy | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Bone Morphogenetic Protein Receptors, Type II - genetics | Rats | Hypertension, Pulmonary - metabolism | Rats, Sprague-Dawley | Bone Morphogenetic Protein Receptors, Type II - metabolism | Disease Progression | Cell Movement - drug effects | Muscle, Smooth, Vascular - pathology | Animals | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Receptors, Transforming Growth Factor beta - metabolism | Hypoxia - pathology | Signal Transduction - physiology | Chronic Disease | Muscle, Smooth, Vascular - enzymology | Transforming Growth Factor beta - metabolism | Index Medicus | Abridged Index Medicus
Journal Article