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Gastroenterology, ISSN 0016-5085, 2010, Volume 139, Issue 2, pp. 418 - 429.e1
Background & Aims Eosinophilic esophagitis (EoE) is caused by immunologic reactions to ingested/inhaled allergens. The diagnosis is considered if ≥15... 
Gastroenterology and Hepatology | Lamina Propria Fibrosis | Topical Corticosteroids | Scoring Tools | Lansoprazole | ELIMINATION DIET | HISTOLOGIC-FINDINGS | ADULTS | SYMPTOMS | PREVALENCE | SKIN PRICK | FLUTICASONE PROPIONATE | PATCH TESTS | CYSTINOSIS | CORTICOSTEROIDS | GASTROENTEROLOGY & HEPATOLOGY | Budesonide - chemistry | Immunohistochemistry | Esophagus - drug effects | Proton Pump Inhibitors - pharmacology | Humans | Child, Preschool | Infant | Male | Esophagitis - pathology | Esophagoscopy | Eosinophilia - pathology | Esophagitis - genetics | 2-Pyridinylmethylsulfinylbenzimidazoles - therapeutic use | Eosinophilia - genetics | Esophagitis - drug therapy | Anti-Inflammatory Agents - administration & dosage | Female | Dosage Forms | Mucous Membrane - drug effects | Transforming Growth Factor beta1 - analysis | Drug Therapy, Combination | Eosinophilia - drug therapy | Child | Promoter Regions, Genetic | Double-Blind Method | Administration, Oral | Placebo Effect | Genotype | Treatment Outcome | Transforming Growth Factor beta1 - genetics | Esophagus - chemistry | Esophagus - pathology | Mucous Membrane - pathology | Phenotype | Anti-Inflammatory Agents - chemistry | Biopsy | Adolescent | Fibrosis | Polymorphism, Single Nucleotide | Budesonide - administration & dosage | Gastroesophageal reflux | Allergens | Budesonide | Antiasthmatic agents | Esophagitis | Clinical trials | Transforming growth factors | Steroids | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Journal of Clinical Periodontology, ISSN 0303-6979, 05/2009, Volume 36, Issue 5, pp. 396 - 403
Dutzan N, Gamonal J, Silva A, Sanz M, Vernal R. Over-expression of forkhead box P3 and its association with receptor activator of nuclear factor-kappa B... 
RANKL | Periodontitis | IL-17 | Treg | CTLA-4 | CD25 | Foxp3 | Regulatory T cells | RORC2 | CYTOKINES | TGF-BETA | SUBPOPULATIONS | MATRIX METALLOPROTEINASE-13 | DENDRITIC CELLS | LYMPHOCYTE | regulatory T cells | INFLAMMATION | DENTISTRY, ORAL SURGERY & MEDICINE | periodontitis | REGULATORY T-CELLS | PARADIGM | Forkhead Transcription Factors - immunology | GATA3 Transcription Factor - immunology | Humans | Interleukin-17 - analysis | Interleukin-17 - immunology | DNA-Binding Proteins - analysis | T-Box Domain Proteins - immunology | Th2 Cells - immunology | Th1 Cells - immunology | Lymphotoxin-alpha - immunology | T-Lymphocytes, Regulatory - immunology | RANK Ligand - immunology | Transforming Growth Factor beta1 - immunology | T-Lymphocytes, Helper-Inducer - immunology | Receptors, Retinoic Acid - immunology | Receptors, Retinoic Acid - analysis | Chronic Periodontitis - immunology | T-Box Domain Proteins - analysis | GATA3 Transcription Factor - analysis | Transforming Growth Factor beta1 - analysis | Interleukin-10 - analysis | Receptors, Thyroid Hormone - immunology | Cytokines - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 | Interleukin-1beta - analysis | DNA-Binding Proteins - immunology | Gene Expression Regulation - genetics | Interleukin-1beta - immunology | RANK Ligand - analysis | Reverse Transcriptase Polymerase Chain Reaction | Disease Progression | Alveolar Bone Loss - immunology | Interferon-gamma - analysis | Receptors, Thyroid Hormone - analysis | Lymphotoxin-alpha - analysis | Down-Regulation - immunology | Interferon-gamma - immunology | Forkhead Transcription Factors - analysis | Interleukin-10 - immunology | Index Medicus | Dentistry
Journal Article
Journal of Periodontology, ISSN 0022-3492, 08/2013, Volume 84, Issue 8, pp. 1180 - 1190
Background: Alveolar bone loss can be a major clinical concern affecting both functionality and esthetics. Osteoblasts are the main cells charged with the... 
intercellular signaling peptides and proteins | osteoblasts | Blood platelets | platelet‐rich plasma | regeneration | bone and bones | Regeneration | Intercellular signaling peptides and proteins | Bone and bones | Osteoblasts | Platelet-rich plasma | STEM-CELLS | DENTAL IMPLANTS | CHEMOTACTIC MIGRATION | MECHANISMS | MEDICINE | platelet-rich plasma | RESPONSES | IN-VITRO | PLATELETS | DENTISTRY, ORAL SURGERY & MEDICINE | MORPHOGENETIC PROTEIN-2 | FIBRIN MATRICES | Hepatocyte Growth Factor - therapeutic use | Intercellular Signaling Peptides and Proteins - analysis | Plasma | Platelet-Derived Growth Factor - therapeutic use | Proto-Oncogene Proteins c-sis - analysis | Humans | Middle Aged | Alveolar Process - drug effects | Male | Autocrine Communication - drug effects | Endothelial Growth Factors - analysis | Alveolar Process - cytology | Osteocalcin - therapeutic use | Platelet-Derived Growth Factor - analysis | Aged, 80 and over | Alkaline Phosphatase - analysis | Adult | Female | Cell Culture Techniques | Endothelial Growth Factors - therapeutic use | Transforming Growth Factor beta1 - analysis | Insulin-Like Growth Factor I - therapeutic use | Osteocalcin - analysis | Bone Regeneration - drug effects | Hepatocyte Growth Factor - analysis | Osteoblasts - drug effects | Vascular Endothelial Growth Factor A - therapeutic use | Cells, Cultured | Vascular Endothelial Growth Factor A - analysis | Chemotaxis - drug effects | Insulin-Like Growth Factor I - analysis | Cell Movement - drug effects | Transforming Growth Factor beta1 - therapeutic use | Proto-Oncogene Proteins c-sis - therapeutic use | Platelet-Rich Plasma | Aged | Cell Proliferation - drug effects | Collagen Type I - analysis | Intercellular Signaling Peptides and Proteins - therapeutic use | Collagen Type I - therapeutic use | Index Medicus | Dentistry
Journal Article
Journal of Pathology, ISSN 0022-3417, 2009, Volume 218, Issue 1, pp. 131 - 142
Common features such as elastic fibre destruction, mucoid accumulation, and smooth muscle cell apoptosis are co-localized in aneurysms of the ascending aorta... 
Decorin | Proteoglycans | LTBP-1 | TGF-/J | PAI-1 | Marfan syndrome | Bicuspid aortic valves | proteoglycans | VASCULAR DEVELOPMENT | MATRIX PROTEIN EXPRESSION | decorin | BINDING-PROTEIN | PATHOLOGY | SPATIAL-PATTERNS | TGF-beta | GROWTH-FACTOR-BETA | ONCOLOGY | bicuspid aortic valves | CONGENITAL BICUSPID VALVE | MARFAN-SYNDROME | TRANSFORMING GROWTH-FACTOR-BETA-1 | SMOOTH-MUSCLE-CELLS | EXTRACELLULAR-MATRIX | Immunohistochemistry | Aortic Aneurysm - metabolism | Humans | Middle Aged | Transforming Growth Factor beta1 - metabolism | RNA, Messenger - analysis | Aorta - metabolism | Case-Control Studies | Immunoblotting - methods | Latent TGF-beta Binding Proteins - analysis | Smad2 Protein - genetics | Statistics, Nonparametric | Aged, 80 and over | Adult | Cell Differentiation | Marfan Syndrome - complications | Transforming Growth Factor beta1 - analysis | Gene Expression | Biomarkers - analysis | Smad2 Protein - metabolism | Transforming Growth Factor beta1 - genetics | Reverse Transcriptase Polymerase Chain Reaction | Marfan Syndrome - genetics | Aorta - pathology | Aortic Aneurysm - complications | Latent TGF-beta Binding Proteins - genetics | Muscle, Smooth, Vascular - pathology | Marfan Syndrome - metabolism | Signal Transduction - physiology | Aged | Aortic Aneurysm - genetics | Smad2 Protein - analysis | Index Medicus
Journal Article
Journal Article
Cardiovascular Pathology, ISSN 1054-8807, 2015, Volume 24, Issue 6, pp. 359 - 367
Abstract Aims Dysregulation of the transforming growth factor beta (TGF-β) 1 pathway has been associated with either syndromic or isolated mitral valve (MV)... 
Pathology | Valvular interstitial cell | Mitral valve prolapse | TGF-β activation | Adherens junction | CARDIAC & CARDIOVASCULAR SYSTEMS | PLAKOPHILIN-2 | POLYMORPHISM | PATHOLOGY | TGF-beta activation | INTERSTITIAL-CELLS | GROWTH-FACTOR-BETA | GENE | MARFAN-SYNDROME | EXTRACELLULAR-MATRIX | VALVULAR DYSTROPHY | UP-REGULATION | CONNECTIVE-TISSUE | Phosphorylation | Mitral Valve - ultrastructure | beta Catenin - analysis | Humans | Middle Aged | Plakophilins - analysis | Male | Mitral Valve - surgery | Myofibroblasts - chemistry | Mitral Valve Prolapse - genetics | Case-Control Studies | Extracellular Matrix - chemistry | gamma Catenin | Collagen Type III - analysis | Actins - analysis | Adult | Cell Transdifferentiation | Female | Filamins - genetics | Transforming Growth Factor beta1 - analysis | Adherens Junctions - chemistry | Signal Transduction | Mitral Valve - chemistry | Mitral Valve Prolapse - metabolism | Mitral Valve Prolapse - pathology | Cadherins - analysis | Mitral Valve Prolapse - surgery | Transforming Growth Factor beta1 - genetics | Desmoplakins - analysis | Myofibroblasts - ultrastructure | Phenotype | Adherens Junctions - ultrastructure | Aged | Collagen Type I - analysis | Smad2 Protein - analysis | Heart valve diseases | Bone morphogenetic proteins | Transforming growth factors | Prolapse | Index Medicus
Journal Article
International Journal of Molecular Medicine, ISSN 1107-3756, 08/2017, Volume 40, Issue 2, pp. 347 - 356
The present study aimed to reveal the metabolic alterations of the extracellular matrix (ECM) in uterosacral ligament (USL) with pelvic organ prolapse (POP)... 
matrix metalloproteinase | transforming growth factor-β1 | tissue inhibitor of matrix metalloproteinases | pelvic organ prolapse | extracellular matrix | Extracellular matrix | Pelvic organ prolapse | Tissue inhibitor of matrix metalloproteinases | Matrix metalloproteinase | Transforming growth factor-β1 | UNITED-STATES | MEDICINE, RESEARCH & EXPERIMENTAL | TISSUE | transforming growth factor-beta 1 | FIBROBLASTS | WOMEN | VAGINAL WALL | GENE-EXPRESSION | UTERINE PROLAPSE | STRESS | EPIDEMIOLOGY | UTEROSACRAL LIGAMENT | Humans | Middle Aged | Transforming Growth Factor beta1 - metabolism | Smad Proteins - analysis | Extracellular Matrix - metabolism | Tissue Inhibitor of Metalloproteinase-2 - metabolism | Matrix Metalloproteinase 9 - metabolism | Pelvic Organ Prolapse - pathology | Proteolysis | Female | Matrix Metalloproteinase 2 - analysis | Transforming Growth Factor beta1 - analysis | Elastin - metabolism | Signal Transduction | Matrix Metalloproteinase 2 - metabolism | Cells, Cultured | Tissue Inhibitor of Metalloproteinase-2 - analysis | Matrix Metalloproteinase 9 - analysis | Pelvic Organ Prolapse - therapy | Elastin - analysis | Collagen - metabolism | Transforming Growth Factor beta1 - therapeutic use | Pelvic Organ Prolapse - metabolism | Collagen - analysis | Extracellular Matrix - pathology | Smad Proteins - metabolism | Proteins | Body mass index | Immunoglobulins | Pathogenesis | Biopsy | Collagen | Surgery | Metabolism | Growth factors
Journal Article
Gene Therapy, ISSN 0969-7128, 05/2007, Volume 14, Issue 10, pp. 790 - 803
Hepatic fibrosis is a dynamic process that involves the interplay of different cell types in the hepatic tissue. Connective tissue growth factor ( CTGF) is a... 
RNA INTERFERENCE | MEDICINE, RESEARCH & EXPERIMENTAL | dimethylnitrosamine | TGF-BETA | COLLAGEN | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIVER FIBROSIS | DOWN-REGULATION | siRNA | N-nitrosodimethylamine | HYALURONIC-ACID | CTGF | connective tissue growth factor | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | FACTOR CTGF | GENETICS & HEREDITY | GENE-EXPRESSION | hepatic fibrosis | SKIN FIBROBLASTS | Immunohistochemistry | Intercellular Signaling Peptides and Proteins - analysis | Liver - pathology | Rats, Wistar | Transforming Growth Factor beta1 - metabolism | Male | Immediate-Early Proteins - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Transfection - methods | RNA Interference | Actins - analysis | Dimethylnitrosamine | Immediate-Early Proteins - analysis | Liver Cirrhosis, Experimental - pathology | Transforming Growth Factor beta1 - analysis | Liver - metabolism | RNA, Small Interfering - pharmacology | Cells, Cultured | Gene Silencing | Intercellular Signaling Peptides and Proteins - genetics | Rats | Transforming Growth Factor beta1 - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Animals | Immediate-Early Proteins - genetics | Fibrosis | Liver Cirrhosis, Experimental - metabolism | Connective Tissue Growth Factor | Genetic Therapy - methods | Prevention | Care and treatment | Physiological aspects | Research | Gene expression | Growth factors | Risk factors | Index Medicus
Journal Article