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Journal Article
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 08/2010, Volume 207, Issue 8, pp. 1589 - 1597
Uncontrolled extracellular matrix production by fibroblasts in response to tissue injury contributes to fibrotic diseases, such as idiopathic pulmonary... 
MEDICINE, RESEARCH & EXPERIMENTAL | RESPONSES | PHOSPHATASE | INJURY | TENSIN HOMOLOG | MECHANISMS | GROWTH-FACTOR | IMMUNOLOGY | MYOFIBROBLAST DIFFERENTIATION | EXPRESSION | CANCER | MICRORNA | Oligonucleotides - genetics | Pulmonary Fibrosis - therapy | Idiopathic Pulmonary Fibrosis - genetics | Gene Expression - drug effects | Gene Expression - genetics | Humans | Actins - metabolism | MicroRNAs - metabolism | Pulmonary Fibrosis - genetics | Idiopathic Pulmonary Fibrosis - metabolism | Actins - genetics | Antisense Elements (Genetics) - therapeutic use | Collagen - genetics | Lung - metabolism | Phosphorylation - drug effects | Smad7 Protein - genetics | Extracellular Matrix Proteins - metabolism | Transforming Growth Factor beta1 - pharmacology | Fibroblasts - metabolism | Smad7 Protein - metabolism | Cell Line | Lung - pathology | Extracellular Matrix Proteins - genetics | Mice, Inbred C57BL | Smad2 Protein - metabolism | Mice, Transgenic | Pulmonary Fibrosis - pathology | Transforming Growth Factor beta1 - genetics | Fibroblasts - pathology | Fibronectins - metabolism | Collagen - metabolism | Animals | Fibroblasts - drug effects | Antisense Elements (Genetics) - genetics | Idiopathic Pulmonary Fibrosis - pathology | Pulmonary Fibrosis - chemically induced | Bleomycin - pharmacology | Fibronectins - genetics | Mice | MicroRNAs - genetics | Index Medicus | Brief Definitive Report
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 05/2009, Volume 219, Issue 2, pp. 449 - 458
Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 10/2008, Volume 317, Issue 1, pp. 43 - 50
Cardiac fibrosis represented as perivascular/interstial fibrosis occurs in patients with hypertension. Oxidative stress has been demonstrated to contribute to... 
Life Sciences | Biochemistry, general | Hypertension | Oxidative stress | Cardiac fibrosis | Oncology | Medical Biochemistry | Cardiology | Angiotensin II | SMOOTH MUSCLE ACTIN | ANGIOTENSIN-CONVERTING ENZYME | CELL BIOLOGY | HEART | PRESSURE OVERLOAD | MYOCARDIAL FIBROSIS | cardiac fibrosis | angiotensin II | TISSUE INHIBITOR | MYOFIBROBLASTS | ALDOSTERONE | hypertension | NF-KAPPA-B | oxidative stress | NADPH OXIDASES | Immunohistochemistry | Membrane Glycoproteins - metabolism | Transforming Growth Factor beta1 - metabolism | NADPH Oxidases - metabolism | Systole - drug effects | RNA, Messenger - metabolism | Tissue Inhibitor of Metalloproteinase-2 - genetics | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Tissue Inhibitor of Metalloproteinase-2 - metabolism | Collagen Type I - genetics | NADPH Oxidases - genetics | Blood Pressure - drug effects | Hypertension - genetics | Fibroblasts - metabolism | Angiotensin II - pharmacology | Collagen Type I - metabolism | RNA, Messenger - genetics | Rats | Myocardium - pathology | Transforming Growth Factor beta1 - genetics | Antioxidants - pharmacology | NADPH Oxidase 2 | Hypertension - physiopathology | Membrane Glycoproteins - genetics | Gene Expression Regulation - drug effects | Tissue Inhibitor of Metalloproteinase-1 - genetics | Myocardium - enzymology | Animals | Models, Biological | Fibroblasts - drug effects | Fibrosis | Hypertension - complications | Oxidative Stress - drug effects | Antioxidants | Proteins | Enzymes | Rodents | Cardiovascular disease | Biochemistry | Gene expression | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, pp. 2516 - 2516
Cancer and stromal cells actively exert physical forces (solid stress) to compress tumour blood vessels, thus reducing vascular perfusion. Tumour interstitial... 
INTERSTITIAL FLUID PRESSURE | BREAST-CANCER | GROWTH-FACTOR-BETA | PANCREATIC STELLATE CELLS | TGF-BETA | AORTIC-ANEURYSM | SOLID STRESS | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | GENE-EXPRESSION | II TYPE-2 RECEPTOR | Index Medicus
Journal Article
Circulation Research, ISSN 0009-7330, 07/2011, Volume 109, Issue 3, pp. e14 - e26
RATIONALE:Systemic sclerosis (SSc) is characterized by widespread microangiopathy, fibrosis, and autoimmunity. Despite the lack of angiogenesis, the expression... 
antiangiogenic agents | systemic sclerosis | peripheral vascular diseases | vascular endothelial growth factor A | angiogenesis | scleroderma | Phosphorylation - physiology | Gene Expression - drug effects | Humans | Transforming Growth Factor beta1 - metabolism | Culture Media, Conditioned - pharmacology | Ischemia - genetics | Vascular Endothelial Growth Factor A - metabolism | RNA-Binding Proteins | Phosphoproteins - metabolism | Vascular Endothelial Growth Factor A - genetics | Gene Expression - physiology | Scleroderma, Systemic - physiopathology | Dermis - blood supply | Neovascularization, Pathologic - physiopathology | Phosphorylation - drug effects | Nuclear Proteins - genetics | Vascular Endothelial Growth Factor A - pharmacology | Endothelial Cells - physiology | Transforming Growth Factor beta1 - pharmacology | Scleroderma, Systemic - metabolism | Cells, Cultured | Scleroderma, Systemic - genetics | Ischemia - metabolism | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Alternative Splicing - physiology | Nuclear Proteins - metabolism | Transforming Growth Factor beta1 - genetics | Ischemia - physiopathology | Phosphoproteins - genetics | Vascular Endothelial Growth Factor B - pharmacology | Signal Transduction - drug effects | Vascular Endothelial Growth Factor B - metabolism | Endothelial Cells - cytology | Serine-Arginine Splicing Factors | Neovascularization, Pathologic - genetics | Signal Transduction - physiology | Vascular Endothelial Growth Factor B - genetics | Neovascularization, Pathologic - metabolism | Index Medicus
Journal Article
Biotechnology and Bioengineering, ISSN 0006-3592, 09/2012, Volume 109, Issue 9, pp. 2357 - 2368
Bioprinting as a promising but unexplored approach for cartilage tissue engineering has the advantages of high throughput, digital control, and highly accurate... 
photoplymerization | cartilage tissue engineering | inkjet printing | chondrocyte | hydrogel | extracellular matrix | Cartilage tissue engineering | Extracellular matrix | Inkjet printing | Hydrogel | Chondrocyte | Photoplymerization | CELLS | SERUM-FREE MEDIUM | HUMAN ARTICULAR CHONDROCYTES | HUMAN EAR CHONDROCYTES | CARTILAGE | IN-VITRO | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | EXPANSION | POLY(ETHYLENE GLYCOL) HYDROGELS | GENE-EXPRESSION | PDGF-BB | Chondrocytes - cytology | Humans | Transforming Growth Factor beta1 - metabolism | Fibroblast Growth Factor 2 - pharmacology | Extracellular Matrix - metabolism | Polyethylene Glycols - chemistry | Methacrylates - chemistry | Photochemical Processes | Tissue Scaffolds - chemistry | Biotechnology - methods | Chondrocytes - drug effects | Hydrogel, Polyethylene Glycol Dimethacrylate | Fibroblast Growth Factor 2 - metabolism | Chondrocytes - metabolism | Transforming Growth Factor beta1 - pharmacology | Tissue Engineering - methods | Extracellular Matrix - drug effects | Cells, Cultured | Polymerization | Proteoglycans - metabolism | Transforming Growth Factor beta1 - genetics | Cartilage - metabolism | Analysis of Variance | Fibroblast Growth Factor 2 - genetics | Histocytochemistry | Biological products | Tissue engineering | Genes | Bone morphogenetic proteins | Fibroblast growth factors | Gene expression | Cartilage | Cell growth | Histology | Gender | Cells | Index Medicus | Human | Bioengineering | Nucleation | Three dimensional printing | Electrochemical machining | Differentiation | Density
Journal Article