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Nature Medicine, ISSN 1078-8956, 03/2012, Volume 18, Issue 3, pp. 441 - 445
Celiac disease is an immune-mediated disorder in which mucosal autoantibodies to the enzyme transglutaminase 2 (TG2)(1) are generated in response to the... 
MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | GERMINAL-CENTER | CELL BIOLOGY | MEMORY B-CELLS | PEPTIDES | AFFINITY | IMMUNE-RESPONSES | HUMAN MONOCLONAL-ANTIBODIES | TISSUE TRANSGLUTAMINASE | ASSOCIATION | RAPID GENERATION | ANTIGEN | Glutens - immunology | Immunoglobulin G - blood | Autoantibodies - blood | Humans | Transglutaminases - blood | Immunoglobulin M - immunology | HLA-DQ Antigens - immunology | Immunoglobulin D - immunology | Transglutaminases - immunology | Celiac Disease - immunology | Immunoglobulin G - immunology | Intestinal Mucosa - immunology | Intestinal Mucosa - enzymology | Escherichia coli - metabolism | Celiac Disease - blood | Plasma Cells - metabolism | Single-Cell Analysis | Somatic Hypermutation, Immunoglobulin | GTP-Binding Proteins - immunology | Autoantibodies - immunology | Immunoglobulin D - blood | Antibody-Producing Cells - immunology | B-Lymphocytes - immunology | Immunoglobulin M - blood | GTP-Binding Proteins - blood | Escherichia coli - genetics | Immunoglobulin A - immunology | Transglutaminases - metabolism | Immunoglobulin A - blood | Mutation | GTP-Binding Proteins - metabolism | Plasma Cells - immunology | Immune response | Gastrointestinal diseases | Colorectal diseases | Plasma cells | Physiological aspects | Genetic aspects | Research | Gluten | Health aspects | Risk factors | Celiac disease | Antigens | Enzymes | Cellular biology | Gene expression | Immune system | Index Medicus
Journal Article
PLoS Medicine, ISSN 1549-1277, 2006, Volume 3, Issue 9, pp. 1637 - 1653
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2017, Volume 199, Issue 2, pp. 782 - 791
Characterization of Ag-specific BCR repertoires is essential for understanding disease mechanisms involving humoral immunity. This is optimally done by... 
TRANSGLUTAMINASE 2-SPECIFIC AUTOANTIBODIES | SOMATIC HYPERMUTATION | AUTOIMMUNITY | LYMPHOCYTE RECEPTOR | REPERTOIRE SEQUENCING DATA | IMMUNOLOGY | HUMAN MONOCLONAL-ANTIBODIES | IMMUNOGLOBULIN HEAVY | RAPID GENERATION | GENE USAGE | ANTIGEN | Glutens - immunology | Humans | Transglutaminases - genetics | Immunoglobulin Variable Region - immunology | Receptors, Antigen, B-Cell - metabolism | Transglutaminases - blood | Autoantigens - genetics | GTP-Binding Proteins - genetics | Transglutaminases - immunology | Young Adult | Celiac Disease - immunology | Adult | Female | Single-Cell Analysis | Immunoglobulin Heavy Chains - immunology | GTP-Binding Proteins - immunology | Autoantigens - chemistry | Receptors, Antigen, B-Cell - immunology | Autoantibodies - immunology | B-Lymphocytes - immunology | GTP-Binding Proteins - blood | Autoantigens - immunology | Immunoglobulin A - immunology | Immunoglobulin Variable Region - genetics | Receptors, Antigen, B-Cell - genetics | High-Throughput Nucleotide Sequencing | Mutation | Immunoglobulin Heavy Chains - genetics | Plasma Cells - immunology | Autoantibodies | Amino acid sequence | Chains | B-cell receptor | Immunoglobulin A | Immunity | Patients | Transglutaminase 2 | Ingestion | Celiac disease | Next-generation sequencing | Lymphocytes B | Interrogation | Plasma cells | Immunity (humoral) | Autoimmune diseases | Gluten | Complementarity-determining region 3 | Index Medicus | Abridged Index Medicus
Journal Article
Molecular Immunology, ISSN 0161-5890, 02/2010, Volume 47, Issue 5, pp. 1010 - 1022
Transglutaminase II (TGase II) is a protein cross-linking enzyme with diverse biological functions. Here we report the role of TGase II in allergic... 
Reactive oxygen species | Allergic inflammation | Histone deacetylase 3 | Snail | Transglutaminase II | HISTONE DEACETYLASE 2 | CANCER-CELLS | FC-EPSILON-RI | TGF-BETA | PROSTAGLANDIN E-2 PRODUCTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CROSS-LINKING | AIRWAY INFLAMMATION | E-CADHERIN | IMMUNOLOGY | TISSUE-TRANSGLUTAMINASE | NF-KAPPA-B | Dinoprostone - secretion | Intramolecular Oxidoreductases - immunology | Reactive Oxygen Species - metabolism | Cadherins - metabolism | Dermatitis, Atopic - enzymology | NF-kappa B - immunology | rac GTP-Binding Proteins - metabolism | NF-kappa B - metabolism | Th2 Cells - immunology | Histone Deacetylases - immunology | Dinoprostone - immunology | Transglutaminases - immunology | Carcinogens - toxicity | rac1 GTP-Binding Protein - immunology | Dermatitis, Atopic - chemically induced | Cadherins - immunology | Anaphylaxis - chemically induced | Reactive Oxygen Species - immunology | Dermatitis, Atopic - immunology | Anaphylaxis - immunology | Transcription, Genetic | Intramolecular Oxidoreductases - metabolism | Matrix Metalloproteinase 2 - immunology | Cytokines - immunology | GTP-Binding Proteins - immunology | Cytokines - secretion | Rats | Histone Deacetylases - metabolism | Neuropeptides - metabolism | Antigens - metabolism | Inflammation - immunology | rac GTP-Binding Proteins - immunology | Anaphylaxis - enzymology | Animals | Tetradecanoylphorbol Acetate - toxicity | Prostaglandin-E Synthases | Transglutaminases - metabolism | Cell Line, Tumor | Antigens - immunology | Matrix Metalloproteinase 2 - secretion | Mice | Mice, Inbred BALB C | Neuropeptides - immunology | Inflammation - enzymology | Th2 Cells - enzymology | rac1 GTP-Binding Protein - metabolism | GTP-Binding Proteins - metabolism | Antigens | Promoters (Genetics) | Cytokines | Atopic dermatitis | Analysis | Prostaglandins E | Leukemia | Immunoglobulin E | Inflammation | Transglutaminases | Universities and colleges | Oxytocics | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, pp. e0134922 - e0134922
A hallmark of the gluten-driven enteropathy celiac disease is autoantibody production towards the enzyme transglutaminase 2 (TG2) that catalyzes the formation... 
AUTOANTIBODIES | ACTIVATION | SPECIFICITY | MULTIDISCIPLINARY SCIENCES | COMPLEXES | CROSS-LINKING | TRANSAMIDATION | TISSUE TRANSGLUTAMINASE | PLASMA-CELLS | CELIAC-DISEASE | ANTIGEN | Glutens - immunology | Autoantigens - metabolism | Humans | Protein Multimerization | Glutamine - metabolism | Transglutaminases - genetics | Receptors, Antigen, B-Cell - metabolism | GTP-Binding Proteins - genetics | Transglutaminases - immunology | Sf9 Cells | T-Lymphocytes - metabolism | Celiac Disease - immunology | Binding Sites - immunology | Lysine - metabolism | Catalysis | Epitopes, T-Lymphocyte - immunology | B-Lymphocytes - metabolism | Recombinant Proteins - metabolism | GTP-Binding Proteins - immunology | Electrophoresis, Polyacrylamide Gel | Models, Molecular | Recombinant Proteins - chemistry | Binding Sites - genetics | Receptors, Antigen, B-Cell - immunology | Lysine - genetics | Animals | B-Lymphocytes - immunology | Glutamine - immunology | Recombinant Proteins - immunology | Autoantigens - immunology | Transglutaminases - metabolism | Glutamine - genetics | Cell Line, Tumor | Protein Conformation | T-Lymphocytes - immunology | Mutation | GTP-Binding Proteins - metabolism | Lysine - immunology | Physiological aspects | Autoantigens | Transglutaminases | B cells | Research | Immunoprecipitation | Peptides | Antibodies | Lymphocytes T | Activation | Photon correlation spectroscopy | Immunoglobulin A | B-cell receptor | Proteins | Signal transduction | Cell activation | Immunology | Lymphocytes | Electrophoresis | Gluten | Recombinant | Enzymes | Antigens | Immunoglobulins | Autoantibodies | Gel electrophoresis | Light scattering | Mass spectroscopy | Crosslinking | Dietary intake | T cell receptors | Epitopes | Immunological tolerance | Transglutaminase 2 | Substrates | Allotypes | CD4 antigen | Celiac disease | Lymphocytes B | Diet | Breakage | Plasma cells | Avidity | Histocompatibility antigen HLA | Autoimmune diseases | Mass spectrometry | Index Medicus
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2016, Volume 72, pp. 33 - 46
Abstract Type 1 diabetes (T1D) is an autoimmune disease characterized by pancreatic β cell destruction induced by islet reactive T cells that have escaped... 
Allergy and Immunology | Post-translational modification | Autoimmunity | ER stress | β cell | Type 1 diabetes | beta cell | APOPTOTIC DEATH | INSULIN-SECRETION | CHROMOGRANIN-A | POSTTRANSLATIONAL MODIFICATIONS | ENDOPLASMIC-RETICULUM STRESS | IMMUNOLOGY | STATISTICAL-MODEL | UNFOLDED PROTEIN RESPONSE | MOUSE MODEL | TISSUE TRANSGLUTAMINASE | PARKINSONS-DISEASE | Calcium - metabolism | Humans | Autoimmunity - genetics | Calcium - immunology | Diabetes Mellitus, Type 1 - metabolism | Transglutaminases - genetics | Endoplasmic Reticulum Stress - genetics | Autoantigens - genetics | GTP-Binding Proteins - genetics | Endoplasmic Reticulum Stress - immunology | Transglutaminases - immunology | CD4-Positive T-Lymphocytes - immunology | Tandem Mass Spectrometry | Insulin-Secreting Cells - metabolism | Autoimmunity - immunology | Chromogranin A - metabolism | Chromogranin A - genetics | Diabetes Mellitus, Type 1 - immunology | Protein Processing, Post-Translational - immunology | Amino Acid Sequence | Cell Line | GTP-Binding Proteins - immunology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Diabetes Mellitus, Type 1 - genetics | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Insulin-Secreting Cells - immunology | Models, Immunological | Animals | Autoantigens - immunology | Transglutaminases - metabolism | Mice, Inbred NOD | Mice, Inbred BALB C | Chromogranin A - immunology | GTP-Binding Proteins - metabolism | Index Medicus | post-translational modification | autoimmunity
Journal Article
PLoS Pathogens, ISSN 1553-7366, 02/2010, Volume 6, Issue 2, pp. e1000763 - e1000763
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 4, pp. 1343 - 1354.e6
Journal Article
Immunity, ISSN 1074-7613, 2004, Volume 21, Issue 3, pp. 367 - 377
Journal Article
The Journal of Immunology, ISSN 0022-1767, 02/2009, Volume 182, Issue 4, pp. 2084 - 2092
Journal Article