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Journal of the National Cancer Institute, ISSN 0027-8874, 04/2011, Volume 103, Issue 8, pp. 645 - 661
Background Ionizing radiation (IR) is effectively used in cancer therapy. However, in subsets of patients, a few radioresistant cancer cells survive and cause... 
STEM-CELLS | IN-VITRO | ONCOLOGY | TYROSINE KINASE | HGF | CELL INVASION | RECEPTOR | EPITHELIAL-MESENCHYMAL TRANSITIONS | NF-KAPPA-B | SCATTER-FACTOR | PROTOONCOGENE | Humans | Neoplasm Invasiveness - prevention & control | Radiation Tolerance | Receptors, Growth Factor - antagonists & inhibitors | NF-kappa B - metabolism | RNA, Messenger - metabolism | NF-kappa B - radiation effects | Receptors, Growth Factor - genetics | Proto-Oncogene Proteins c-met - radiation effects | Signal Transduction - radiation effects | Protein-Serine-Threonine Kinases - metabolism | Radiation, Ionizing | Tumor Suppressor Proteins - metabolism | DNA-Binding Proteins - radiation effects | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Cell Cycle Proteins - metabolism | Cell Cycle Proteins - radiation effects | Receptors, Growth Factor - radiation effects | Proto-Oncogene Proteins c-met - drug effects | Ataxia Telangiectasia Mutated Proteins | Phosphorylation - radiation effects | Cell Line, Tumor | Mice | RNA, Small Interfering | Tumor Suppressor Proteins - radiation effects | Receptors, Growth Factor - metabolism | Neoplasms - metabolism | Proto-Oncogene Proteins c-met - metabolism | Apoptosis - radiation effects | Up-Regulation - radiation effects | Transcription, Genetic - radiation effects | Transplantation, Heterologous | Sulfones - pharmacology | DNA-Binding Proteins - metabolism | Chromatin Immunoprecipitation | Protein-Serine-Threonine Kinases - radiation effects | Tumor Suppressor Proteins - genetics | Polymerase Chain Reaction | Cell Cycle Proteins - genetics | Indoles - pharmacology | Neoplasms - radiotherapy | Gene Expression Regulation, Neoplastic - drug effects | In Situ Nick-End Labeling | Enzyme-Linked Immunosorbent Assay | Radiation-Sensitizing Agents - pharmacology | Gene Silencing | Protein-Serine-Threonine Kinases - genetics | DNA-Binding Proteins - genetics | Cell Survival - radiation effects | Cell Movement - radiation effects | Proto-Oncogene Proteins c-met - genetics | Blotting, Northern | Animals | NF-kappa B - genetics | Protein Kinase Inhibitors - pharmacology | Neoplasms - pathology | Receptors, Growth Factor - drug effects | DNA Damage - radiation effects | Mitogen-Activated Protein Kinases - metabolism | Ionizing radiation | Physiological aspects | Genetic aspects | Cancer invasiveness | Research | Gene expression | Radiotherapy | Health aspects
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2011, Volume 81, Issue 3, pp. 888 - 893
Purpose The purpose of this study was to quantify the relationship of bone marrow response to radiation dose, using 3’-deoxy-3’-[18 F]fluorothymidine ([18... 
Radiology | Hematology, Oncology and Palliative Medicine | Bone marrow | 3’-deoxy-3’-[18F]fluorothymidine | Radiation response | Toxicity | Dose | PET | F]fluorothymidine | 3'-deoxy-3'- | CONCURRENT CISPLATIN | CHEMORADIATION THERAPY | INTENSITY-MODULATED RADIOTHERAPY | PELVIC RADIOTHERAPY | CERVICAL-CANCER | NECK-CANCER | CHEMOTHERAPY | ACUTE HEMATOLOGIC TOXICITY | GYNECOLOGIC MALIGNANCIES | ONCOLOGY | F-18-FLT PET | 3 '-deoxy-3 '-[F-18]fluorothymidine | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Radiotherapy Dosage | Bone Marrow Cells - cytology | Radiotherapy Planning, Computer-Assisted - methods | Humans | Tomography, X-Ray Computed | Bone Marrow - radiation effects | Bone Marrow Cells - radiation effects | Positron-Emission Tomography - methods | Dideoxynucleosides | Bone Marrow Cells - diagnostic imaging | Head and Neck Neoplasms - radiotherapy | Bone Marrow - diagnostic imaging | Fluorine Radioisotopes | Dose-Response Relationship, Radiation | Cell Proliferation - radiation effects | Pets | Radiation | Index Medicus | TOMOGRAPHY | HEAD | HOURS LIVING RADIOISOTOPES | EMISSION COMPUTED TOMOGRAPHY | BONE MARROW | RADIATION DOSES | ANIMAL TISSUES | CAT SCANNING | SKELETON | ORGANIC HALOGEN COMPOUNDS | FLUORINE ISOTOPES | NANOSECONDS LIVING RADIOISOTOPES | POSITRON COMPUTED TOMOGRAPHY | VERTEBRAE | BETA DECAY RADIOISOTOPES | RADIOLOGY AND NUCLEAR MEDICINE | HEMATOPOIETIC SYSTEM | LIGHT NUCLEI | BETA-PLUS DECAY RADIOISOTOPES | DIAGNOSTIC TECHNIQUES | NEOPLASMS | ORGANIC FLUORINE COMPOUNDS | ISOMERIC TRANSITION ISOTOPES | ORGANIC COMPOUNDS | RADIOISOTOPES | TOXICITY | COMPUTERIZED TOMOGRAPHY | ISOTOPES | ORGANS | DISEASES | NUCLEI | DOSES | NECK | ODD-ODD NUCLEI | BODY | FLUORINE 18
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 11/2011, Volume 81, Issue 3, pp. 698 - 705
Purpose Our hypothesis was that pretreatment inflammation in the lung makes pulmonary tissue more susceptible to radiation damage. The relationship between... 
Radiology | Hematology, Oncology and Palliative Medicine | Radiation-induced lung toxicity (RILT) | Positron emission tomography (PET) | Pneumonitis | Dyspnea | Fluorodeoxyglucose (FDG) | Lung | MANAGEMENT | TISSUE DOSE CONSTRAINTS | INDUCED PNEUMONITIS | DISORDERS | RISK | CHEMOTHERAPY | POSITRON-EMISSION-TOMOGRAPHY | PRESCRIPTION | ONCOLOGY | INFECTION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET | Carcinoma, Non-Small-Cell Lung - radiotherapy | Fluorodeoxyglucose F18 - pharmacokinetics | Age Factors | Humans | Lung Neoplasms - metabolism | Middle Aged | Lung Neoplasms - radiotherapy | Male | Tomography, X-Ray Computed | Dyspnea - etiology | Lung - diagnostic imaging | Positron-Emission Tomography | Chemoradiotherapy | Radiation Pneumonitis - metabolism | Multimodal Imaging - methods | Aged, 80 and over | Adult | Female | Lung - radiation effects | Lung - metabolism | Retrospective Studies | Odds Ratio | Radiopharmaceuticals - pharmacokinetics | Carcinoma, Non-Small-Cell Lung - metabolism | Radiation Pneumonitis - diagnostic imaging | Logistic Models | Lung Neoplasms - diagnostic imaging | Aged | Carcinoma, Non-Small-Cell Lung - diagnostic imaging | Cancer patients | Lung cancer, Non-small cell | Radiotherapy | Developmental biology | Risk factors | Radiation | Toxicity | Lung cancer | Tomography | Inflammation | Respiration | Age | Tumors | Index Medicus | TOMOGRAPHY | HOURS LIVING RADIOISOTOPES | EMISSION COMPUTED TOMOGRAPHY | LUNGS | RADIATION EFFECTS | FLUORODEOXYGLUCOSE | RADIATION DOSES | MEDICINE | CAT SCANNING | ANTIMETABOLITES | FLUORINE ISOTOPES | THERAPY | NANOSECONDS LIVING RADIOISOTOPES | POSITRON COMPUTED TOMOGRAPHY | HYPOTHESIS | DRUGS | BETA DECAY RADIOISOTOPES | RADIOLOGY AND NUCLEAR MEDICINE | PNEUMONITIS | RADIOTHERAPY | LIGHT NUCLEI | RADIOLOGY | BETA-PLUS DECAY RADIOISOTOPES | DIAGNOSTIC TECHNIQUES | NEOPLASMS | ISOMERIC TRANSITION ISOTOPES | RADIOISOTOPES | TOXICITY | SYMPTOMS | COMPUTERIZED TOMOGRAPHY | NUCLEAR MEDICINE | ISOTOPES | ORGANS | DISEASES | NUCLEI | DOSES | RESPIRATORY SYSTEM | INFLAMMATION | ODD-ODD NUCLEI | BODY | PATHOLOGICAL CHANGES | FLUORINE 18 | HAZARDS
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e83392
MicroRNA (miRNA)-mediated regulation of the cellular transcriptome is an important epigenetic mechanism for fine-tuning regulatory pathways. These include... 
INDUCED DNA-DAMAGE | TARGET GENES | HEPATOCELLULAR-CARCINOMA | NONMELANOMA SKIN-CANCER | THYROID-HORMONE | MULTIDISCIPLINARY SCIENCES | BASAL-CELL CARCINOMA | MALIGNANT-MELANOMA | MESENCHYMAL TRANSITION | IDENTIFICATION | RADIATION | Keratinocytes - radiation effects | Humans | Neoplasms, Radiation-Induced - etiology | MicroRNAs - metabolism | Carcinogenesis - metabolism | Carcinogenesis - radiation effects | Neoplasms, Radiation-Induced - genetics | Computer Simulation | Signal Transduction - radiation effects | Promoter Regions, Genetic | Membrane Proteins - genetics | Carcinogenesis - genetics | Cells, Cultured | MicroRNAs - radiation effects | Monomeric GTP-Binding Proteins - genetics | Gene Expression - radiation effects | Neoplasms, Radiation-Induced - metabolism | Ultraviolet Rays - adverse effects | Skin Neoplasms - metabolism | Keratinocytes - metabolism | Regulatory Elements, Transcriptional | Skin Neoplasms - genetics | Gene Regulatory Networks - radiation effects | MicroRNAs - genetics | Skin Neoplasms - etiology | Epigenetic inheritance | Ionizing radiation | MicroRNA | Analysis | Development and progression | Skin | Skin cancer | Phosphorylation | Homology | Biology | Regulatory sequences | Metastasis | Carcinogenesis | Metastases | Liver cancer | Carcinogens | Pathways | Deoxyribonucleic acid--DNA | Medical research | Dermatology | U.V. radiation | MiRNA | Melanoma | Keratinocytes | Exposure | Gene expression | Ribonucleic acid--RNA | Signaling | Ultraviolet radiation | MicroRNAs | Irradiation | Cancer | Apoptosis | RNA | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2010, Volume 77, Issue 2, pp. 350 - 356
Purpose Clinical applicability of a multiple-threshold method for [18 F]fluoro-2-deoxyglucose (FDG) activity in radiation treatment planning was evaluated.... 
Radiology | Hematology, Oncology and Palliative Medicine | Threshold value | FDG | Radiation treatment planning | Positron emission tomography | FDG-PET | GROSS TUMOR VOLUME | PARAAORTIC LYMPH-NODES | CERVICAL-CARCINOMA | CT | TARGET VOLUME DELINEATION | NASOPHARYNGEAL CARCINOMA | NECK CANCERS | ONCOLOGY | CONFORMAL RADIOTHERAPY | IMAGE FUSION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Fluorodeoxyglucose F18 - pharmacokinetics | Pharyngeal Neoplasms - radiotherapy | Radiopharmaceuticals - pharmacokinetics | Humans | Middle Aged | Lung Neoplasms - radiotherapy | Tomography, X-Ray Computed - methods | Lung Neoplasms - pathology | Male | Pharyngeal Neoplasms - diagnostic imaging | Survival Rate | Positron-Emission Tomography - methods | Tumor Burden | Young Adult | Lymphatic Metastasis - diagnostic imaging | Aged, 80 and over | Adult | Female | Lung Neoplasms - diagnostic imaging | Pharyngeal Neoplasms - pathology | Aged | Radiotherapy Planning, Computer-Assisted | Lymph Nodes - diagnostic imaging | Medical colleges | CT imaging | Care and treatment | Analysis | Lung cancer | Radiation | Radiotherapy | Methods | Cancer | TOMOGRAPHY | HOURS LIVING RADIOISOTOPES | DIGESTIVE SYSTEM | EMISSION COMPUTED TOMOGRAPHY | LUNGS | FLUORODEOXYGLUCOSE | MEDICINE | LYMPHATIC SYSTEM | PLANNING | PHARYNX | ANTIMETABOLITES | FLUORINE ISOTOPES | THERAPY | NANOSECONDS LIVING RADIOISOTOPES | POSITRON COMPUTED TOMOGRAPHY | DRUGS | BETA DECAY RADIOISOTOPES | RADIOLOGY AND NUCLEAR MEDICINE | RADIOTHERAPY | LIGHT NUCLEI | RADIOLOGY | BETA-PLUS DECAY RADIOISOTOPES | DIAGNOSTIC TECHNIQUES | NEOPLASMS | LYMPH NODES | ISOMERIC TRANSITION ISOTOPES | RADIOISOTOPES | SIMULATION | COMPUTERIZED TOMOGRAPHY | NUCLEAR MEDICINE | ISOTOPES | ORGANS | DISEASES | NUCLEI | RESPIRATORY SYSTEM | ODD-ODD NUCLEI | BODY | FLUORINE 18
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2011, Volume 79, Issue 1, pp. 137 - 142
Purpose To evaluate changes in [18 F]fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) standardized uptake values (SUV) in uveal... 
Radiology | Hematology, Oncology and Palliative Medicine | Eye | FDG | Choroidal melanoma | PET | FDG-PET/CT | CERVICAL-CARCINOMA | TUMOR RESPONSE | CANCER | F-18-FDG PET | B-CELL LYMPHOMA | ONCOLOGY | RADIOTHERAPY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | SUV-BASED ASSESSMENT | Fluorodeoxyglucose F18 - pharmacokinetics | Melanoma - diagnostic imaging | Follow-Up Studies | Humans | Middle Aged | Tomography, X-Ray Computed - methods | Male | Choroid Neoplasms - pathology | Neoplasm Recurrence, Local - pathology | Choroid Neoplasms - radiotherapy | Neoplasm Recurrence, Local - diagnostic imaging | Aged, 80 and over | Adult | Female | Retrospective Studies | Uveal Neoplasms - diagnostic imaging | Choroid Neoplasms - diagnostic imaging | Radioisotopes - therapeutic use | Radiopharmaceuticals - pharmacokinetics | Uveal Neoplasms - pathology | Brachytherapy - methods | Melanoma - radiotherapy | Melanoma - pathology | Positron-Emission Tomography - methods | Tumor Burden | Palladium - therapeutic use | Aged | Uveal Neoplasms - radiotherapy | Neoplasm Staging | CT imaging | Care and treatment | PET imaging | Radiotherapy | Melanoma | Cancer | Scanning | Computed tomography | Lasers | Brachytherapy | Metabolism | Positron emission tomography | Plaques | Metastases | Tumors | TOMOGRAPHY | HEAD | HOURS LIVING RADIOISOTOPES | EYES | EMISSION COMPUTED TOMOGRAPHY | FLUORODEOXYGLUCOSE | MELANOMAS | MEDICINE | CAT SCANNING | ANTIMETABOLITES | FLUORINE ISOTOPES | THERAPY | NANOSECONDS LIVING RADIOISOTOPES | POSITRON COMPUTED TOMOGRAPHY | DRUGS | BETA DECAY RADIOISOTOPES | RADIOLOGY AND NUCLEAR MEDICINE | EPITHELIOMAS | LIGHT NUCLEI | RADIOLOGY | BETA-PLUS DECAY RADIOISOTOPES | DIAGNOSTIC TECHNIQUES | NEOPLASMS | ISOMERIC TRANSITION ISOTOPES | RADIOISOTOPES | COMPUTERIZED TOMOGRAPHY | SENSE ORGANS | NUCLEAR MEDICINE | ISOTOPES | ORGANS | DISEASES | NUCLEI | UPTAKE | CARCINOMAS | ODD-ODD NUCLEI | BRACHYTHERAPY | BODY | FACE | FLUORINE 18
Journal Article
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2011, Volume 81, Issue 3, pp. 615 - 622
Purpose Positron emission-tomography (PET) using 2-[18 F]fluoro-2-deoxyglucose (FDG-PET) increases sensitivity and specificity of disease detection in lymphoma... 
Radiology | Hematology, Oncology and Palliative Medicine | PET/CT radiation planning | Target volume definition | Lymphoma | [18F]FDG-PET | Involved field radiation | F]FDG-PET | FDG-PET | GROSS TUMOR VOLUME | INTENSITY-MODULATED RADIOTHERAPY | INVOLVED FIELD | [F-18]FDG-PET | NECK-CANCER | CELL LUNG-CANCER | POSITRON-EMISSION | ONCOLOGY | CLINICAL IMPACT | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | STAGE HODGKIN-LYMPHOMA | Hodgkin Disease - diagnostic imaging | Radiotherapy Planning, Computer-Assisted - methods | Humans | Middle Aged | Male | Tomography, X-Ray Computed | Positron-Emission Tomography | Lymphoma, Non-Hodgkin - diagnostic imaging | Tumor Burden | Cancer Care Facilities | Lymphoma, Non-Hodgkin - radiotherapy | Neoplasms, Plasma Cell - diagnostic imaging | Neoplasms, Plasma Cell - radiotherapy | New York City | Young Adult | Hodgkin Disease - radiotherapy | Multimodal Imaging - methods | Aged, 80 and over | Adult | Female | Fluorodeoxyglucose F18 | Aged | Retrospective Studies | Radiopharmaceuticals | CT imaging | Pets | Care and treatment | PET imaging | Radiation | Drug therapy | Radiotherapy | Cancer | alpha Radiation | Computed tomography | Plasma cells | Malignancy | Dosimetry | Hodgkin's disease | Tumors | TOMOGRAPHY | HOURS LIVING RADIOISOTOPES | EMISSION COMPUTED TOMOGRAPHY | IMMUNE SYSTEM DISEASES | SENSITIVITY | PLASMA CELLS | RADIATION DOSES | ANIMAL CELLS | CAT SCANNING | LYMPHOMAS | FLUORINE ISOTOPES | NANOSECONDS LIVING RADIOISOTOPES | POSITRON COMPUTED TOMOGRAPHY | BETA DECAY RADIOISOTOPES | RADIOLOGY AND NUCLEAR MEDICINE | SOMATIC CELLS | CONNECTIVE TISSUE CELLS | LIGHT NUCLEI | BETA-PLUS DECAY RADIOISOTOPES | DIAGNOSTIC TECHNIQUES | SPECIFICITY | NEOPLASMS | ISOMERIC TRANSITION ISOTOPES | RADIOISOTOPES | SIMULATION | COMPUTERIZED TOMOGRAPHY | ISOTOPES | DISEASES | NUCLEI | DOSES | ODD-ODD NUCLEI | DOSIMETRY | FLUORINE 18
Journal Article
CELL DEATH & DISEASE, ISSN 2041-4889, 10/2013, Volume 4, Issue 10, pp. e875 - e875
Radioresistance is a major challenge in prostate cancer (CaP) radiotherapy (RT). In this study, we investigated the role and association of... 
BEZ235 | RADIATION SENSITIVITY | IDENTIFICATION | EMT | PI3K/Akt/mTOR | CELL BIOLOGY | CSC | IN-VITRO | radiation therapy | PROTEASOME | RESISTANCE | INHIBITOR | Prostate cancer | radioresistance | Prostatic Neoplasms - radiotherapy | Epithelial-Mesenchymal Transition - radiation effects | TOR Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Apoptosis - radiation effects | Neoplastic Stem Cells - drug effects | Humans | Spheroids, Cellular - pathology | Epithelial-Mesenchymal Transition - drug effects | Male | Phosphatidylinositol 3-Kinases - metabolism | Spheroids, Cellular - radiation effects | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Quinolines - pharmacology | Radiation Tolerance - radiation effects | TOR Serine-Threonine Kinases - antagonists & inhibitors | Neoplastic Stem Cells - pathology | Spheroids, Cellular - drug effects | Imidazoles - therapeutic use | Signal Transduction - radiation effects | Proto-Oncogene Proteins c-akt - metabolism | Prostatic Neoplasms - drug therapy | Prostatic Neoplasms - pathology | Reproducibility of Results | Neoplasm Invasiveness | Imidazoles - pharmacology | Enzyme Activation - drug effects | Enzyme Activation - radiation effects | Radiation Tolerance - drug effects | Phenotype | Animals | Cell Cycle Checkpoints - radiation effects | Signal Transduction - drug effects | Cell Cycle Checkpoints - drug effects | Models, Biological | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Quinolines - therapeutic use | Neoplastic Stem Cells - enzymology | PI3K | mTOR | Akt | Original
Journal Article
Advanced Optical Materials, ISSN 2195-1071, 07/2019, Volume 7, Issue 14, pp. 1801666 - n/a
Journal Article
Astrophysical Journal Letters, ISSN 2041-8205, 04/2017, Volume 839, Issue 1, p. L10
Journal Article