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translatome (79) 79
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Cell Reports, ISSN 2211-1247, 10/2017, Volume 21, Issue 4, pp. 953 - 965
Genetic alterations impacting ubiquitously expressed proteins involved in RNA metabolism often result in neurodegenerative conditions, with increasing evidence... 
motor neuron disease | SMN | neurodegeneration | ribosome | translatome | spinal muscular atrophy | polysomal profiling | RNA-BINDING PROTEINS | UBIQUITIN HOMEOSTASIS | SURVIVAL | LOCALIZATION | DEFECTS | MESSENGER-RNA | GENE | MOUSE-MODEL | SCHWANN-CELLS | MOTOR-NEURON PROTEIN | CELL BIOLOGY
Journal Article
The EMBO Journal, ISSN 0261-4189, 07/2019, Volume 38, Issue 13, p. n/a
Loaded into ARGONAUTE(AGO) proteins, eukaryotic micro(mi)RNAs regulate gene expression via cleavage, translational repression, and/or accelerated decay of... 
miRoot | microRNA | translatome | targetome | AGO1 | ARABIDOPSIS ROOT | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRAFFICKING | TRANSLATION | CELL BIOLOGY | INHIBITION | REPRESSION | ANNOTATION | GENES | MESSENGER-RNA DECAY | EXPRESSION | Mosaics | Immunoprecipitation | Gene regulation | MiRNA | Organs | Genomes | Gene expression | Ribonucleic acid--RNA | Activity patterns | Data integration | Interrogation | Experimentation | Cell migration
Journal Article
Cell Reports, ISSN 2211-1247, 10/2018, Volume 25, Issue 4, pp. 1097 - 1108.e5
Ribosome profiling, or Ribo-seq, is based on large-scale sequencing of RNA fragments protected from nuclease digestion by ribosomes. Thanks to its unique... 
ribosome profiling | translation | puromycin | protein synthesis | ribosome | translatome | translational control | polysomal profiling | proteome | PUROMYCIN | MESSENGER-RNA TRANSLATION | NUCLEOTIDE RESOLUTION | ELONGATION | IN-VIVO | GENOME-WIDE ANALYSIS | DYNAMICS | PROTEIN-SYNTHESIS | LIVE CELLS | REVEALS | CELL BIOLOGY
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 05/2019, Volume 20, Issue 9, p. 2177
Glioblastoma (GBM) is one of the most aggressive cancers, with median survival of less than 2 years. Despite of considerable advance in molecular... 
Tumor heterogeneity | Translatome | Polysome | mTORC1 | Glioblastoma | Translation control | polysome | translatome | glioblastoma | translation control | tumor heterogeneity
Journal Article
2016, ISBN 9780444636010, Volume 49
Many diarylheptanoids were isolated from the galangal (rhizome of ). We are reported the antitumor-promoting, antiinflammatory, cytotoxic, antiinfluenza virus,... 
Bioactivity | Alpinia officinarum | Synthesis | Translatome | Diarylheptanoid
Book Chapter
Trends in Genetics, ISSN 0168-9525, 03/2019, Volume 35, Issue 3, pp. 186 - 198
The translatome can be defined as the sum of the RNA sequences that are translated into proteins in the cell by the ribosomal machinery. Until recently, it was... 
open reading frame | translatome | micropeptide | de novo protein | ribosome profiling | TRANSCRIPTS | PEPTIDES | LONG NONCODING RNAS | MESSENGER-RNA | GENE | RIBOSOME PROFILING REVEALS | LANDSCAPE | IN-VIVO | GENETICS & HEREDITY | MICROPEPTIDE | PROTEINS
Journal Article
Theranostics, ISSN 1838-7640, 2019, Volume 9, Issue 14, pp. 4141 - 4155
Despite the critical position of translation in the multilevel gene expression regulation program, high-resolution and genome-wide view of the landscape of RNA... 
Journal Article
Comptes Rendus - Biologies, ISSN 1631-0691, 02/2018, Volume 341, Issue 2, pp. 65 - 74
With the advent of next-generation sequencing technologies, identifying the translatome, which includes genome-wide ribosome-associated mRNAs, provides new... 
G protein-coupled receptor | Translatome | Polysome profiling | Ribosome profiling | Translating ribosome affinity purification
Journal Article
Journal of Proteome Research, ISSN 1535-3893, 01/2014, Volume 13, Issue 1, pp. 38 - 49
To estimate the potential of the state-of-the-art proteomics technologies on full coverage of the encoding gene products, the Chinese Human Chromosome Proteome... 
translatome | SAP | missing protein | transcriptome | chromosome | proteome | BIOCHEMICAL RESEARCH METHODS | GENE-EXPRESSION | PROTEINS | CANCER | STOMACH | Protein Biosynthesis | Humans | Mass Spectrometry | Transcriptome | Cell Line, Tumor | Proteome | Gene Expression Profiling
Journal Article
Biochemical Journal, ISSN 0264-6021, 11/2015, Volume 472, Issue 1, pp. 83 - 95
Staphylococcal alpha-hemolysin (AHL) is a clinically relevant toxin, whose effects on host translation are poorly understood. We characterized genome-wide... 
Bacterial toxins | RNA-binding protein | Translatome | HuR | Pore-forming toxins | Transcriptome | Polysomal profiling | Translational control
Journal Article
2018, ISBN 9782889454136
Plants, as sessile organisms, are exposed to a large array of challenging external and internal alterations that may restrict plant growth. These limiting... 
translatome | mRNA translation | translation factors | organellar gene expression | post-transcriptional regulation
eBook
Journal of experimental neuroscience, ISSN 1179-0695, 2019, Volume 13, p. 1179069519870182
The neuroplasticity hypothesis of depression proposes that major depressive disorders are related to decreased hippocampal and cortical neural plasticity,... 
Journal Article
CEREBRAL CORTEX, ISSN 1047-3211, 09/2019, Volume 29, Issue 9, pp. 3813 - 3827
Cortical D2 dopamine receptor (Drd2) have mostly been examined in the context of cognitive function regulation and neurotransmission modulation of medial... 
prefrontal cortex | MOUSE | claustrum | IN-SITU HYBRIDIZATION | binary reporter mouse | insula | NEUROSCIENCES | sensory cortices | orphan receptors | RiboTag | Dopamine D2 receptor | MESSENGER-RNA | GENE-EXPRESSION | ANTIPSYCHOTIC-DRUGS | LOCUS-COERULEUS | translatome | INTERNEURONS | MODULATION
Journal Article
Cell, ISSN 0092-8674, 06/2019, Volume 178, Issue 1, pp. 242 - 260.e29
Journal Article