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Journal Article
Genes and Development, ISSN 0890-9369, 03/2019, Volume 33, Issue 5-6, pp. 282 - 287
Here we show that translesion synthesis (TLS) opposite 1, N-6-ethenodeoxyadenosine (edA), which disrupts Watson-Crick base pairing, occurs via Pol iota/Pol... 
εdA lesion | DNA polymerase θ | Translesion synthesis | Hoogsteen base pairing | BYPASS | PROTEIN | DNA polymerase theta | MOUSE | DEVELOPMENTAL BIOLOGY | DAMAGE | CELL BIOLOGY | YEAST | ETA | edA lesion | GENETICS & HEREDITY | translesion synthesis | ERROR-FREE REPLICATION
Journal Article
Critical Reviews in Biochemistry and Molecular Biology, ISSN 1040-9238, 07/2018, Volume 53, Issue 4, pp. 382 - 402
Journal Article
NATURE STRUCTURAL & MOLECULAR BIOLOGY, ISSN 1545-9993, 12/2013, Volume 20, Issue 12, pp. 1383 - 1389
DNA replication forks that collapse during the process of genomic duplication lead to double-strand breaks and constitute a threat to genomic stability. The... 
DORMANT ORIGINS | HUMAN-CELLS | TOLERANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSLESION SYNTHESIS | EXCESS MCM2-7 | MECHANISMS | CELL BIOLOGY | BIOPHYSICS | POLYMERASES | INTEGRITY | RESTART | PROTEINS
Journal Article
The EMBO Journal, ISSN 0261-4189, 03/2013, Volume 32, Issue 5, pp. 742 - 755
Completion of DNA replication needs to be ensured even when challenged with fork progression problems or DNA damage. PCNA and its modifications constitute a... 
PCNA SUMOylation | genome stability | Srs2 | SUMO interacting motif | DNA repair synthesis | UBIQUITIN CONJUGATION | CELL NUCLEAR ANTIGEN | RAD51 PRESYNAPTIC FILAMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSLESION SYNTHESIS | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | POLYMERASE-DELTA | POSTREPLICATION REPAIR | HOMOLOGOUS RECOMBINATION | DAMAGED REPLICATION FORKS | MITOTIC RECOMBINATION | Genomic Instability | DNA Polymerase III - genetics | Saccharomyces cerevisiae - genetics | DNA Repair - radiation effects | Homologous Recombination | DNA Repair - genetics | DNA Polymerase II - metabolism | Saccharomyces cerevisiae - metabolism | Proliferating Cell Nuclear Antigen - genetics | SUMO-1 Protein - genetics | DNA Replication - radiation effects | DNA Damage - genetics | DNA Helicases - genetics | DNA Polymerase II - genetics | Rad51 Recombinase - metabolism | Rad51 Recombinase - genetics | Saccharomyces cerevisiae Proteins - genetics | Mutation - genetics | Ultraviolet Rays - adverse effects | DNA Helicases - metabolism | Saccharomyces cerevisiae Proteins - metabolism | DNA Replication - genetics | Sumoylation | SUMO-1 Protein - metabolism | DNA Polymerase III - metabolism | Proliferating Cell Nuclear Antigen - metabolism | DNA Damage - radiation effects | Molecular biology | Genetic recombination | DNA repair | Cell cycle
Journal Article
Cell, ISSN 0092-8674, 06/2019, Volume 178, Issue 1, pp. 152 - 159.e11
Intrinsic and acquired drug resistance and induction of secondary malignancies limit successful chemotherapy. Because mutagenic translesion synthesis (TLS)... 
REV7 | chemoresistance | REV1 | cisplatin | chemotherapy | translesion synthesis | POL ζ | COMPLEX | REPAIR | DNA-POLYMERASE DELTA | RECOGNITION | CISPLATIN | POL-ZETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | INHIBITOR | ACCESSORY SUBUNITS | CELL BIOLOGY | DNA polymerases | Development and progression | Chemotherapy | Drug resistance | Melanoma | Cancer
Journal Article
Molecular Cell, ISSN 1097-2765, 2010, Volume 37, Issue 5, pp. 714 - 727
Journal Article
NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 03/2019, Volume 47, Issue 5, pp. 2425 - 2435
DNA polymerase (pol ) is best known for its ability to bypass UV-induced thymine-thymine (T-T) dimers and other bulky DNA lesions, but pol also has other... 
REPLICATION | PCNA | CELL NUCLEAR ANTIGEN | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | POL-ETA | IN-VIVO | TRANSLESION SYNTHESIS | SACCHAROMYCES-CEREVISIAE | FRAGILE SITE STABILITY | LEADING-STRAND
Journal Article
Molecular Neurobiology, ISSN 0893-7648, 3/2018, Volume 55, Issue 3, pp. 2506 - 2515
In the peripheral nervous system (PNS) in the absence of tight blood barrier, neurons are at increased risk of DNA damage, yet the question of how effectively... 
Neurology | Neurosciences | Biomedicine | Translesion synthesis (TLS) | DNA damage | Neurobiology | Peripheral nervous system (PNS) | Dorsal root ganglion (DRG) | DNA polymerase kappa (Pol κ) | Cisplatin | Cell Biology | Nucleotide excision repair (NER) | ERROR-FREE BYPASS | POL-KAPPA | DNA polymerase kappa (Pol kappa) | MAMMALIAN-CELLS | NEUROSCIENCES | LESION BYPASS | NUCLEOTIDE-EXCISION-REPAIR | Y-FAMILY | GENOME INTEGRITY | PERIPHERAL NEUROPATHY | INTERSTRAND CROSS-LINKS | REGULATED EXPRESSION | DNA-Directed DNA Polymerase - biosynthesis | Gene Transfer Techniques | RNA, Small Interfering - genetics | DNA Repair - drug effects | Mice, Inbred C57BL | Cells, Cultured | DNA Repair - physiology | Male | Antineoplastic Agents - toxicity | Animals | Cisplatin - toxicity | Ganglia, Spinal - pathology | Mice | Ganglia, Spinal - drug effects | RNA, Small Interfering - administration & dosage | Ganglia, Spinal - metabolism | Neurons | Genetic transcription | Ganglion | DNA repair | Genetic polymorphisms | Neurophysiology | Chemotherapy | Analysis | DNA | DNA polymerases | Cancer | Drugs | Cell survival | Transcription | DNA polymerase | Attention | Nervous system | siRNA | Thymidine | Ganglia | DNA biosynthesis | Neurotoxicity | Dorsal root ganglia | Platinum | Immunoreactivity | Lesions | Deoxyribonucleic acid--DNA | DNA-directed DNA polymerase | Index Medicus | Nucleotide Excision Repair (NER) | Translesion Synthesis (TLS) | Peripheral Nervous System (PNS) | cisplatin | Dorsal Root Ganglion (DRG)
Journal Article
Cell Cycle, ISSN 1538-4101, 02/2010, Volume 9, Issue 4, pp. 729 - 735
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 11/2015, Volume 22, Issue 11, pp. 844 - 847
Journal Article
Molecular Cell, ISSN 1097-2765, 04/2014, Volume 54, Issue 1, pp. 107 - 118
Journal Article