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science & technology (189) 189
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humans (169) 169
transmembrane activator and caml interactor protein - metabolism (109) 109
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1. Full Text TNF receptor superfamily member 13b ( TNFRSF13B ) hemizygosity reveals transmembrane activator and CAML interactor haploinsufficiency at later stages of B-cell development
by Romberg, Neil, MD and Virdee, Manmeet, BS and Chamberlain, Nicolas, BS and Oe, Tyler, BA and Schickel, Jean-Nicolas, PhD and Perkins, Tiffany, MD and Cantaert, Tineke, PhD and Rachid, Rima, MD and Rosengren, Sally, MD and Palazzo, Regina, MD and Geha, Raif, MD, PhD and Cunningham-Rundles, Charlotte, MD, PhD and Meffre, Eric, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 136, Issue 5, pp. 1315 - 1325
Allergy and Immunology | B-cell tolerance | Smith-Magenis syndrome | transmembrane activator and CAML interactor | TNFRSF13B | common variable immune deficiency | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Autoimmunity | Common Variable Immunodeficiency - immunology | Humans | Middle Aged | Male | Mutation, Missense - genetics | Haploinsufficiency | Hemizygote | T-Lymphocytes, Regulatory - immunology | Transmembrane Activator and CAML Interactor Protein - metabolism | Young Adult | Transmembrane Activator and CAML Interactor Protein - genetics | Lymphocyte Activation - genetics | B-Lymphocytes - immunology | Smith-Magenis Syndrome - immunology | Adolescent | Aged, 80 and over | Adult | Female | Immunologic Memory | Aged | Child | Antibody Formation - genetics | Broadway theater | Medical colleges | Tumor necrosis factor | Analysis | Immunodeficiency | B cells | Studies | Medical research | Flow cytometry | Cell growth | Genes | Ear diseases | Ligands | Mutation | Index Medicus | Abridged Index Medicus
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2. Full Text Transmembrane activator and CAML interactor (TACI) haploinsufficiency results in B-cell dysfunction in patients with Smith-Magenis syndrome
by Chinen, Javier, MD, PhD and Martinez-Gallo, Monica, PhD and Gu, Wenli, PhD and Cols, Montserrat, PhD and Cerutti, Andrea, MD and Radigan, Lin and Zhang, Li, PhD and Potocki, Lorraine, MD and Withers, Marjorie, MS and Lupski, James R., MD, PhD and Cunningham-Rundles, Charlotte, MD, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2011, Volume 127, Issue 6, pp. 1579 - 1586
Allergy and Immunology | B cell | Smith-Magenis syndrome | transmembrane activator and CAML interactor | humoral immunity | common variable immunodeficiency | gene haploinsufficiency | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Immunopathology | Complex syndromes | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Medical genetics | Biological and medical sciences | Medical sciences | Immunodeficiencies. Immunoglobulinopathies | Immunodeficiencies | Chromosome Deletion | Cytidine Deaminase - genetics | Humans | RNA, Messenger - genetics | Child, Preschool | Infant | Male | Chromosomes, Human, Pair 17 - genetics | Haploinsufficiency | Young Adult | Smith-Magenis Syndrome - genetics | Transmembrane Activator and CAML Interactor Protein - genetics | B-Lymphocytes - immunology | Immunity, Humoral | Base Sequence | Smith-Magenis Syndrome - immunology | Adolescent | Adult | Female | Mutation | Toll-Like Receptor 9 - metabolism | Child | Cohort Studies | Fluorescence | Respiratory tract diseases | Care and treatment | Pyrimidines | Genetic disorders | Molecular genetics | Proteins | Lymphocytes | Rodents | Ligands | Protein expression | Infections | Chromosomes | Age | Immune system | Index Medicus | Abridged Index Medicus | CVID | Gene haploinsufficiency | Smith-Magenis Syndrome | TACI | Humoral immunity
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3. Full Text Cracking the BAFF code
by Schneider, Pascal and Mackay, Fabienne
Nature reviews. Immunology, ISSN 1474-1733, 07/2009, Volume 9, Issue 7, pp. 491 - 502
Life Sciences & Biomedicine | Immunology | Science & Technology | B-Cell Maturation Antigen - immunology | Tumor Necrosis Factor Ligand Superfamily Member 13 - immunology | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - immunology | Humans | Toll-Like Receptors - immunology | Tumor Necrosis Factor Ligand Superfamily Member 13 - metabolism | Tumor Necrosis Factor Receptor-Associated Peptides and Proteins - metabolism | Transmembrane Activator and CAML Interactor Protein - metabolism | Signal Transduction - immunology | Lymphocyte Activation - immunology | Animals | B-Cell Activating Factor - metabolism | B-Cell Maturation Antigen - metabolism | B-Lymphocyte Subsets - metabolism | Autoimmunity - immunology | Immune Tolerance - immunology | B-Cell Activating Factor - immunology | B-Lymphocyte Subsets - immunology | Ligands | Toll-Like Receptors - metabolism | Transmembrane Activator and CAML Interactor Protein - immunology | Autoimmunity | Physiological aspects | B cells | Research | Tumor necrosis factor | Risk factors | Index Medicus
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4. Full Text Primary B Cell Immunodeficiencies: Comparisons and Contrasts
by Conley, Mary Ellen and Dobbs, A. Kerry and Farmer, Dana M and Kilic, Sebnem and Paris, Kenneth and Grigoriadou, Sofia and Coustan-Smith, Elaine and Howard, Vanessa and Campana, Dario
Annual review of immunology, ISSN 0732-0582, 2009, Volume 27, Issue 1, pp. 199 - 227
Btk | Common variable immunodeficiency | TACI | X-linked agammaglobulinemia | Hyper-IgM syndrome | Inducible T-Cell Co-Stimulator Protein | CD79 Antigens - immunology | Protein-Tyrosine Kinases - metabolism | Humans | Precursor Cells, B-Lymphoid - metabolism | Precursor Cells, B-Lymphoid - immunology | Antigens, CD19 - genetics | Protein-Tyrosine Kinases - immunology | Transmembrane Activator and CAML Interactor Protein - metabolism | Protein-Tyrosine Kinases - genetics | Adaptor Proteins, Signal Transducing - immunology | Immunologic Deficiency Syndromes - immunology | B-Lymphocytes - metabolism | Antigens, CD19 - immunology | Antigens, Differentiation, T-Lymphocyte - immunology | Antigens, Differentiation, T-Lymphocyte - metabolism | CD79 Antigens - metabolism | Transmembrane Activator and CAML Interactor Protein - genetics | Animals | B-Lymphocytes - immunology | Adaptor Proteins, Signal Transducing - genetics | Antigens, Differentiation, T-Lymphocyte - genetics | Immunologic Deficiency Syndromes - genetics | Antigens, CD19 - metabolism | CD79 Antigens - genetics | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Transmembrane Activator and CAML Interactor Protein - immunology | Genetic aspects | B cells | Properties | Identification and classification | Immunodeficiency | Immunological research | Index Medicus
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5. Full Text TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts
by Bossen, Claudia and Cachero, Teresa G and Tardivel, Aubry and Ingold, Karine and Willen, Laure and Dobles, Max and Scott, Martin L and Maquelin, Aris and Belnoue, Elodie and Siegrist, Claire-Anne and Chevrier, Stéphane and Acha-Orbea, Hans and Leung, Helen and Mackay, Fabienne and Tschopp, Jürg and Schneider, Pascal
Blood, ISSN 0006-4971, 2008, Volume 111, Issue 3, pp. 1004 - 1012
Life Sciences & Biomedicine | Hematology | Science & Technology | Up-Regulation | Cell Proliferation | Spleen - immunology | Immunoglobulins - immunology | Humans | Molecular Sequence Data | Transmembrane Activator and CAML Interactor Protein - metabolism | Antibodies - immunology | Transmembrane Activator and CAML Interactor Protein - deficiency | Immunoglobulins - biosynthesis | B-Lymphocytes - metabolism | B-Cell Activation Factor Receptor - immunology | Amino Acid Sequence | Cell Line | Antibody Formation - immunology | B-Lymphocytes - cytology | Signal Transduction | Lymphocyte Activation | B-Cell Activating Factor - chemistry | Mice, Transgenic | Tumor Necrosis Factor Ligand Superfamily Member 13 - metabolism | Mice, Knockout | Transmembrane Activator and CAML Interactor Protein - genetics | B-Cell Activation Factor Receptor - metabolism | Sequence Alignment | Animals | B-Cell Activating Factor - metabolism | B-Lymphocytes - immunology | Histocompatibility Antigens Class II - immunology | B-Cell Activating Factor - genetics | Ligands | Tumor Necrosis Factor Ligand Superfamily Member 13 - genetics | Mice | Index Medicus | Abridged Index Medicus
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6. Full Text Signaling by the tumor necrosis factor receptor superfamily in B‐cell biology and disease
by Rickert, Robert C and Jellusova, Julia and Miletic, Ana V
Immunological reviews, ISSN 0105-2896, 11/2011, Volume 244, Issue 1, pp. 115 - 133
BAFF | B cell | CD40 | BCMA | NF‐κB | TACI | NF-κB | Life Sciences & Biomedicine | Immunology | Science & Technology | Cell Proliferation | Humans | NF-kappa B - immunology | NF-kappa B - metabolism | Transmembrane Activator and CAML Interactor Protein - metabolism | Signal Transduction - immunology | CD40 Antigens - metabolism | B-Cell Activating Factor - immunology | B-Lymphocyte Subsets - immunology | CD40 Antigens - genetics | B-Cell Activation Factor Receptor - genetics | B-Lymphocytes - metabolism | B-Cell Activation Factor Receptor - immunology | B-Cell Maturation Antigen - immunology | Tumor Necrosis Factor Ligand Superfamily Member 13 - immunology | Gene Expression | Mice, Transgenic | Cell Survival - immunology | Immunity, Innate | Tumor Necrosis Factor Ligand Superfamily Member 13 - metabolism | Transmembrane Activator and CAML Interactor Protein - genetics | B-Cell Activation Factor Receptor - metabolism | Animals | B-Cell Activating Factor - metabolism | B-Cell Maturation Antigen - metabolism | B-Lymphocytes - immunology | B-Lymphocyte Subsets - metabolism | NF-kappa B - genetics | B-Cell Activating Factor - genetics | Neoplasms - immunology | Autoimmune Diseases | Tumor Necrosis Factor Ligand Superfamily Member 13 - genetics | Mice | B-Cell Maturation Antigen - genetics | Transmembrane Activator and CAML Interactor Protein - immunology | CD40 Antigens - immunology | Autoimmunity | Antigens | Tumor necrosis factor | Tumors | Necrosis | Index Medicus
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7. Full Text Transmembrane activator and calcium-modulating cyclophilin ligand interactor mutations in common variable immunodeficiency: Clinical and immunologic outcomes in heterozygotes
by Zhang, Li and Radigan, Lin and Salzer, Ulrich, MD and Behrens, Timothy W., MD and Grimbacher, Bodo, MD and Diaz, George, MD, PhD and Bussel, James, MD and Cunningham-Rundles, Charlotte, MD, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2007, Volume 120, Issue 5, pp. 1178 - 1185
Allergy and Immunology | B cell | IgA | TACI | IgG |